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Displaying drugs 126 - 150 of 14564 in total
Pegfilgrastim is a PEGylated form of the recombinant human granulocyte colony-stimulating factor (G-CSF) analogue, filgrastim. The drug is approved for use to decrease the incidence of infection, as manifested by febrile neutropenia, in susceptible patients with with non-myeloid cancer receiving myelosuppressive anti-cancer treatment. Although the risk of developing febrile neutropenia...
Approved
Matched Description: … [A187607] First developed by Amgen, pegfilgrastim was initially approved by the FDA in 2002 and marketed ... [A187601] The drug is approved for use to decrease the incidence of infection, as manifested by febrile ... Pegfilgrastim is a PEGylated form of the recombinant human granulocyte colony-stimulating factor (G-CSF …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Pelgraz 6 mg solution for injection in a pre-filled syringe ... NUFILONG SOLUTION FOR INJECTION IN A PRE-FILLED SYRINGE 6MG/0.6ML ... ENJEKSIYON ICIN KULLANIMA HAZIR SIRINGA, 1 ADET …
Oxybenzone is an organic compound used in sunscreens. It is a derivative of benzophenone. It forms colorless crystals that are readily soluble in most organic solvents. It is used as an ingredient in sunscreen and other cosmetics because it absorbs UV-A ultraviolet rays.
Approved
Investigational
Matched Description: … Oxybenzone is an organic compound used in sunscreens. It is a derivative of benzophenone. ... It is used as an ingredient in sunscreen and other cosmetics because it absorbs UV-A ultraviolet rays ... It forms colorless crystals that are readily soluble in most organic solvents. …
Matched Mixtures name: … Sun Of A Beach SPF 30 ... Hope In A Tinted Moisturizer ... Hope In A Jar SPF 25 …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Activation of the Raf-MEK-ERK signalling pathway is known to be implemented in several types of malignancies; thus, mitogen-activated protein kinase kinase (MEK) inhibitors such as selumetinib are important tools that can target the problematic overactivity of this pathway. Results from clinical trials investigating earlier developed MEK inhibitors were underwhelming. However,...
Approved
Investigational
Matched Iupac: … 5-[(4-bromo-2-chlorophenyl)amino]-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-1,3-benzodiazole-6-carboxamide …
Matched Description: … [A193608] It is a genetic, autosomal dominant condition resulting from mutations of the NF1 gene, which ... of Neurofibromatosis type 1 (NF-1) in a limited age group. ... [A193608] Luckily, the use of selumetinib in patients with NF-1 have shown efficacy in shrinking associated …
Matched Categories: … Mitogen-Activated Protein Kinase Kinase 1 Inhibitors …
Diethylamino hydroxybenzoyl hexyl benzoate is a UV filter with high absorption in the UV-A range. Minimizing the overexposure of human skin to ultraviolet radiation that may lead to acute and chronic photodamage, diethylamino hydroxybenzoyl hexyl benzoate is an oil-soluble UV filter that may be incorporated in the oil phase of...
Approved
Matched International brands: … Uvinul A Plus …
Matched Description: … Diethylamino hydroxybenzoyl hexyl benzoate is a UV filter with high absorption in the UV-A range. ... the oil phase of emulsions [F107]. ... Minimizing the overexposure of human skin to ultraviolet radiation that may lead to acute and chronic …
Matched Mixtures name: … The History of Whoo Jin Hae Yoon Sun ... Ohui The First Cell Revolution Age Control Sun Block ... D-one By Tamdoan Bb Light …
Also known as Ethylhexyl Salicylate. Octyl salicylate is an oil soluble chemical sunscreen agent that absorbs UVB radiation. It does not protect against UVA. Octyl salicylate is used to augment the UVB protection in a sunscreen. Salicylates are weak UVB absorbers and they are generally used in combination with other...
Approved
Investigational
Matched Description: … Octyl salicylate is used to augment the UVB protection in a sunscreen. ... The salicylate portion of the molecule absorbs ultraviolet light to protect skin from the harmful effects ... It covers wavelength in the range 295-315 nm, peak at 307-310 nm. …
Matched Mixtures name: … Hope In A Jar SPF 25 ... SIMPLI DAY All In One SmartCream SPF 42 ... Olay Total Effects 7-IN-1 Anti-aging Uv Moisturizer Plus Touch Of Foundation …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Encorafenib, also known as BRAFTOVI, is a kinase inhibitor. Encorafenib inhibits BRAF gene, which encodes for B-raf protein, which is a proto-oncogene involved in various genetic mutations. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which impacts cell division, differentiation, and secretion. Mutations in this gene,...
Approved
Investigational
Matched Iupac: … methyl N-[(2S)-1-({4-[3-(5-chloro-2-fluoro-3-methanesulfonamidophenyl)-1-(propan-2-yl)-1H-pyrazol-4-yl …
Matched Description: … Mutations in this gene, most frequently the V600E mutation, are the most commonly identified cancer-causing ... Encorafenib inhibits BRAF gene, which encodes for B-raf protein, which is a proto-oncogene involved in ... melanoma with a BRAF V600E or V600K mutation, as detected by an FDA-approved test. …
Matched Products: … BRAFTOVİ 75 MG SERT KAPSÜL, 42 ADET …
Dupilumab is a fully human monoclonal antibody of the immunoglobulin G4 subclass that binds to the interleukin-4 (IL-4) receptor, inhibiting the receptor signaling pathways. As an interleukin-4 receptor alpha antagonist, dupilumab inhibits the signaling of pro-inflammatory cytokines, called interleukins (IL), that induce inflammatory and immunological reactions in several atopic or...
Approved
Investigational
Matched Description: … Dupilumab is a fully human monoclonal antibody of the immunoglobulin G4 subclass that binds to the interleukin ... It was first approved by the FDA in 2017. ... [A180478] As an interleukin-4 receptor alpha antagonist, dupilumab inhibits the signaling of pro-inflammatory …
Matched Products: … DUPIXENT SOLUTION FOR INJECTION IN A PRE-FILLED SYRINGE 300 mg/2ml ... DUPIXENT SOLUTION FOR INJECTION IN A PRE-FILLED SYRINGE 200 mg/1.14ml ... Dupixent 300 mg Solution for Injection in Pre-filled Syringe …
Naphazoline is a rapid acting imidazoline sympathomimetic vasoconstrictor of ocular or nasal artierioles[L5804,L5807]. It acts to decrease congestion and is found in many over the counter (OTC) eye drops and nasal preparations[L5804,L5807]. Naphazoline was first developed in 1942 as a nasal formulation for congestion .
Approved
Investigational
Matched Iupac: … 2-[(naphthalen-1-yl)methyl]-4,5-dihydro-1H-imidazole …
Matched Description: … Naphazoline is a rapid acting imidazoline sympathomimetic vasoconstrictor of ocular or nasal artierioles ... It acts to decrease congestion and is found in many over the counter (OTC) eye drops and nasal preparations ... Naphazoline was first developed in 1942 as a nasal formulation for congestion[A176609]. …
Matched Mixtures name: … FENIXIL-OF ... Clear Eyes Acr By Murine ... Opcon-A
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Adrenergic alpha-1 Receptor Agonists …
Matched Products: … Clear Eyes By Murine Eye Dps ... NAFAZOLINA CLORHIDRATO 1 MG/ML. SOLUCIÓN OFTÁLMICA …
Homosalate is an organic compound that belongs to salicylates. It is an ester formed from salicylic acid and 3,3,5-trimethylcyclohexanol, a derivative of cyclohexanol. Salicylates prevent direct skin exposure to the sun’s harmful rays by absorbing ultraviolet (UV) light. Homosalate specifically absorbs short-wave UVB rays, which are associated with DNA damage...
Approved
Investigational
Matched Description: … It is a common ingredient in many commercially available sunscreens. ... Salicylates prevent direct skin exposure to the sun’s harmful rays by absorbing ultraviolet (UV) light ... It is an ester formed from salicylic acid and 3,3,5-trimethylcyclohexanol, a derivative of cyclohexanol …
Matched Mixtures name: … Hope In A Jar SPF 25 ... Gloves in a Bottle with SPF15 ... 4-IN-1 Broad Spectrum SPF 50 Sunscreen …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Ever since its discovery and availability for sale and use in the late 1940s, lidocaine has become an exceptionally commonly used medication . In particular, lidocaine's principal mode of action in acting as a local anesthetic that numbs the sensations of tissues means the agent is indicated for facilitating local...
Approved
Vet approved
Matched International brands: … Lidoject-1
Matched Description: … In particular, lidocaine's principal mode of action in acting as a local anesthetic that numbs the sensations ... It ultimately elicits its numbing activity by blocking sodium channels so that the neurons of local tissues ... In doing so, however, it can block or decrease muscle contractile, resulting in effects like vasodilation …
Matched Mixtures name: … Holy Water Mercy In A Bottle ... Mlp A-1 ... ANALGEN NF
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … Fruit of the Earth Sun Town City ... Fruit of the Earth Aloe Vera Cool Blue ... Fruit of the Earth Cool Blue Aloe Mist Continuous …
An isomer of 1-propanol. It is a colorless liquid having disinfectant properties. It is used in the manufacture of acetone and its derivatives and as a solvent. Topically, it is used as an antiseptic.
Approved
Investigational
Matched Description: … It is used in the manufacture of acetone and its derivatives and as a solvent. ... An isomer of 1-propanol. It is a colorless liquid having disinfectant properties. …
Matched Mixtures name: … Sooth-a-Sting ... Diclo Gel 1% Pak ... The New Parent First Aid …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … The Essence of Eva ... Coghlans Survival In A Can ... 2 in 1 Hand Sanitizer/Disinfectant …
Nalmefene, a 6-methylene analogue of naltrexone, is an opioid receptor antagonist. It acts as an antagonist at the mu (μ)-opioid and delta (δ)-opioid receptors and a partial agonist at the kappa (κ)-opioid receptor. In Europe, nalmefene oral tablets are used to reduce alcohol consumption in adults with alcohol dependence. Nalmefene...
Approved
Investigational
Withdrawn
Matched Description: … [L40684] The nasal spray formulation of nalmefene was approved by the FDA in May 2023.[L46511] ... Nalmefene, a 6-methylene analogue of [naltrexone], is an opioid receptor antagonist. ... [L40684] It acts as an antagonist at the mu (μ)-opioid and delta (δ)-opioid receptors and a partial agonist …
Matched Categories: … Drugs Used in Alcohol Dependence ... Drugs Used in Addictive Disorders …
Matched Products: … SELINCRO 18MG FILM KAPLI TABLET ,42 TABLET …
A colloidal system of semisolid hydrocarbons obtained from petroleum. It is used as an ointment base, topical protectant, and lubricant.
Approved
Investigational
Matched Description: … A colloidal system of semisolid hydrocarbons obtained from petroleum. …
Matched Mixtures name: … CARMEX Multi-Symptom 3 in 1 COLD Sore treatment External Analgesic Skin Protectant ... Nivea A Kiss of Intense Moisture Healing Medicated Lip Care ... Chapstick 12 Days of Christmas …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Care One Medicated Lip Balm in a Pot ... Procurevitamin A and D Vitamin A and D ... ProcureVITAMIN A AND D VITAMIN A AND D …
Omacetaxine mepesuccinate (formerly known as HHT or Homoharringtonine), is a cephalotaxine ester and protein synthesis inhibitor with established clinical activity as a single agent in hematological malignancies. Omacetaxine mepesuccinate is synthesized from cephalotaxine, which is an extract from the leaves of the plant, Cephalotaxus species. In October 2005, omacetaxine mepesuccinate...
Approved
Investigational
Matched Synonyms: … 1-[(1S,3aR,14bS)-2-Methoxy-1,5,6,8,9,14b-hexahydro-4H-cyclopenta[a][1,3]dioxolo[4,5-H]pyrrolo[2,1-b][ ... 3]benzazepin-1-yl] 4-methyl (2R)-2-hydroxy-2-(4-hydroxy-4-methylpentyl)butanedioate …
Matched Iupac: … (19)-tetraen-3-yl 1-methyl (3R)-3-hydroxy-3-(4-hydroxy-4-methylpentyl)butanedioate ... (2S,3S,6R)-4-methoxy-16,18-dioxa-10-azapentacyclo[11.7.0.0^{2,6}.0^{6,10}.0^{15,19}]icosa-1(20),4,13,15 …
Matched Description: … by the FDA. ... Then in March 2006, it received Orphan Drug status from the FDA for the treatment of CML. ... In November 2006, omacetaxine mepesuccinate, for the treatment of CML, was granted Fast Track designation …
Enasidenib is an orally available treatment for the treatment of adult patients with relapsed or refractory acute myeloid leukemia (AML) with specific mutations in the isocitrate dehydrogenase 2 (IDH2) gene, which is a recurrent mutation detected in 12-20% of adult patients with AML [A20344, A20345]. Patients eligible for this treatment...
Approved
Investigational
Matched Synonyms: … 2-Methyl-1-(4-(6-(trifluoromethyl)pyridin-2-yl)-6-(2-(trifluoromethyl)pyridin-4-ylamino)-1,3,5-triazin …
Matched Iupac: … 2-methyl-1-({4-[6-(trifluoromethyl)pyridin-2-yl]-6-{[2-(trifluoromethyl)pyridin-4-yl]amino}-1,3,5-triazin …
Matched Description: … Patients eligible for this treatment are selected by testing the presence of IDH2 mutations in the blood ... acute myeloid leukemia (AML) with specific mutations in the isocitrate dehydrogenase 2 (IDH2) gene, ... which is a recurrent mutation detected in 12-20% of adult patients with AML [A20344, A20345]. …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... UGT1A1 Substrates with a Narrow Therapeutic Index ... UGT1A3 Substrates with a Narrow Therapeutic Index ... UGT1A9 Substrates with a Narrow Therapeutic Index ... UGT2B7 Substrates with a Narrow Therapeutic Index …
Clostridium tetani toxoid antigen (formaldehyde inactivated) is a vaccine for intramuscular injection. It is used for active immunization of children 7 years of age or older, and adults, for prevention of tetanus. The toxoid in the Clostridium tetani culture is grown and detoxified followed by purification via ammonium sulfate filtration...
Approved
Matched Description: … The toxoid in the Clostridium tetani culture is grown and detoxified followed by purification via ammonium ... Clostridium tetani toxoid antigen (formaldehyde inactivated) is a vaccine for intramuscular injection ... It is used for active immunization of children 7 years of age or older, and adults, for prevention of
Matched Mixtures name: … FINAL BULK OF ADSORBED TD VACCINE ... Repevax Injektionssuspension in einer Fertigspritze ... Covaxis Injektionssuspension in einer Fertigspritze …
Matched Products: … TETAVAX single dose, suspension for injection in a prefilled syringe ... TETAVAX 0.5 ML IM/SC ENJEKSİYON İÇİN SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET …
Infliximab is a tumor necrosis factor (TNF-alpha or TNF-α) blocker and a chimeric monoclonal IgG1 antibody composed of human constant (75%) and murine variable (25%) regions . Infliximab is produced by a recombinant cell line cultured by continuous perfusion. Tumor necrosis factor-alpha (TNF-α) is a key proinflammatory cytokine involved in...
Approved
Matched Description: … In December 2017, Ixifi, a second biosimilar that was developed by Pfizer, was granted approval by the ... There are currently two biosilimars of infliximab available in the US market that demonstrate a high ... In clinical trials, multiple infusions of infliximab displayed in a reduction of signs and symptoms of
Matched Products: … REMSIMA SOLUTION FOR SUBCUTANEOUS INJECTION 120 MG/ML IN PRE-FILLED PEN ... REMSIMA SOLUTION FOR SUBCUTANEOUS INJECTION 120 MG/ML IN PRE-FILLED SYRINGE ... INFUZYON COZELTISI HAZIRLAMAK ICIN LIYOFILIZE TOZ ICEREN FLAKON, 1 ADET …
Interferon a (human leukocyte protein moiety reduced). A type I interferon consisting of 165 amino acid residues with lysine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent. An oral form is...
Approved
Investigational
Matched International brands: … Roferon A
Matched Description: … A type I interferon consisting of 165 amino acid residues with lysine in position 23. ... Interferon a (human leukocyte protein moiety reduced). ... This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes …
Matched Products: … ROFERON-A 3 MIU IU ENEJKSİYONA HAZIR ŞIRINGA, 1 ADET ... ROFERON-A 6 MIU IU ENEJKSİYONA HAZIR ŞIRINGA, 1 ADET ... ROFERON-A 9 MIU IU ENEJKSİYONA HAZIR ŞIRINGA, 1 ADET …
Onasemnogene abeparvovec is an adeno-associated virus vector-based gene therapy that has been approved by the FDA in May 2019 for the treatment of infant patients (less than 2 years of age) with spinal muscular atrophy (SMA) and a specific mutation in the survival motor neuron 1 (SMN1) gene. SMA is...
Approved
Matched Description: … atrophy (SMA) and a specific mutation in the survival motor neuron 1 (SMN1) gene. ... [Nusinersen] is another gene therapy that is currently approved by the FDA for the treatment of SMA in ... by the FDA in May 2019 for the treatment of infant patients (less than 2 years of age) with spinal muscular …
Matched Categories: … Cellular and Gene Therapy …
Risdiplam is an orally bioavailable mRNA splicing modifier used for the treatment of spinal muscular atrophy (SMA). It increases systemic SMN protein concentrations by improving the efficiency of SMN2 gene transcription. This mechanism of action is similar to its predecessor nusinersen, the biggest difference being their route of administration: nusinersen...
Approved
Investigational
Matched Iupac: … 7-{4,7-diazaspiro[2.5]octan-7-yl}-2-{2,8-dimethylimidazo[1,2-b]pyridazin-6-yl}-4H-pyrido[1,2-a]pyrimidin …
Matched Description: … [L15351,A216871] Risdiplam was approved by the FDA in August 2020 for the treatment of spinal muscular ... [L12615] It increases systemic SMN protein concentrations by improving the efficiency of _SMN2_ gene ... route of administration: nusinersen requires intrathecal administration, as does the one-time gene therapy …
Matched Categories: … Survival of Motor Neuron 2 Splicing Modifier ... MATE 1 Inhibitors ... Heterocyclic Compounds, 1-Ring …
Lanolin is a yellow fat obtained from sheep's wool. It is used as an emollient, cosmetic, and pharmaceutic aid . The US federal code of regulations states that lanolin in the concentration range of 12-50% may be included in over the counter skin ointments . Lanolin is the purified, secreted...
Approved
Matched Description: … The US federal code of regulations states that lanolin in the concentration range of 12-50% may be included ... Lanolin is used in the protection, treatment, and cosmetic enhancement of human skin. ... Lanolin is a yellow fat obtained from sheep's wool. …
Matched Mixtures name: … Vitamin A D ... Vitamin A D ... Vitamin A D …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Lantiseptic by Dermarite Dry Skin Therapy ... Lantiseptic by DermaRite Original Skin Protectant …
A synthetic fluoroquinolone (fluoroquinolones) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA gyrase.
Approved
Matched Synonyms: … 1-Ethyl-6-fluor-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-chinolincarbonsäure ... 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid ... 1,4-Dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid …
Matched Iupac: … 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … A synthetic fluoroquinolone (fluoroquinolones) with broad-spectrum antibacterial activity against most …
Matched Categories: … Metabolic Side Effects of Drugs and Substances …
Matched Products: … S-ORIPOL® NF 400 MG …
Loperamide is an anti-diarrheal agent that is available as various over-the-counter products for treating diarrhea. The drug was first synthesized in 1969 and used medically in 1976. It is a highly lipophilic synthetic phenylpiperidine opioid that is structurally similar to opiate receptor agonists such as diphenoxylate and haloperidol. Due to...
Approved
Matched Iupac: … 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide …
Matched Description: … [L42785] The drug was first synthesized in 1969 and used medically in 1976. ... [A251610, A251625] However, loperamide is associated with a risk for experiencing a range of adverse ... Loperamide is an anti-diarrheal agent that is available as various over-the-counter products for treating …
Matched Mixtures name: … Doc in the Box All Day Supply ... Meds on the Go …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … PANGETAN NF TABLETAS ... DIATROL SYRUP 1 mg/5 ml ... A D …
Approved
Investigational
Matched Mixtures name: … FINAL BULK OF ADSORBED TD VACCINE ... Repevax Injektionssuspension in einer Fertigspritze ... Covaxis Injektionssuspension in einer Fertigspritze …
Matched Products: … Diphtheria Toxoid Immunization Of Reactors …
Extracted from the dried leaves of bearberry plant in the genus Arctostaphylos and other plants commonly in the Ericaceae family, arbutin is a beta-D-glucopyranoside of DB09526. It is found in foods, over-the-counter drugs, and herbal dietary supplements . Most commonly, it is an active ingredient in skincare and cosmetic products...
Approved
Matched Description: … in the _Ericaceae_ family, arbutin is a beta-D-glucopyranoside of [DB09526]. ... Arbutin is a competitive inhibitor of tyrosinase (E.C.1.14.18.1) in melanocytes [A27248], and the inhibition ... Extracted from the dried leaves of bearberry plant in the genus _Arctostaphylos_ and other plants commonly …
Matched Mixtures name: … The Prestige BB SPF25 PA 2Plus ... The Oriental Gold BB SPF25 PA 2Plus ... Dr G Whitening REFORMER by EGF …
Displaying drugs 126 - 150 of 14564 in total