Belladonna Alkaloids

Name
Belladonna Alkaloids
Accession Number
DBCAT000763
Description

Alkaloids obtained from various plants, especially the deadly nightshade (Atropa belladonna), variety acuminata; atropine, hyoscyamine and scopolamine are classical, specific antimuscarinic agents with many pharmacologic actions; used mainly as antispasmodics.

Drugs
DrugDrug Description
IpratropiumAn anticholinergic drug used in the control of symptoms related to bronchospasm in chronic obstructive pulmonary disease (COPD).
HyoscyamineAn anticholinergic indicated to treat functional gastrointestinal disorders, biliary and renal colic, and acute rhinitis.
AtropineA muscarinic antagonist used to treat poisoning by muscarinic agents, including organophosphates and other drugs.
ScopolamineA belladonna alkaloid with anticholinergic effects indicated for the treatment of nausea and vomiting associated with motion sickness and postoperative nausea and vomiting (PONV).
FentoniumFentonium is an atropine derivative.
MethylatropineNot Annotated
ButropiumA medication indicated to treat pain caused by gastrointestinal inflammation and ulcers, or diseases of the gallbladder.
Drugs & Drug Targets
DrugTargetType
IpratropiumMuscarinic acetylcholine receptor M1target
IpratropiumMuscarinic acetylcholine receptor M2target
IpratropiumMuscarinic acetylcholine receptor M3target
IpratropiumSolute carrier family 22 member 5transporter
IpratropiumSolute carrier family 22 member 4transporter
IpratropiumSerum albumincarrier
Ipratropiumalpha1-acid glycoproteincarrier
HyoscyamineMuscarinic acetylcholine receptor M1target
HyoscyamineMuscarinic acetylcholine receptor M2target
HyoscyamineMuscarinic acetylcholine receptor M3target
HyoscyamineMuscarinic acetylcholine receptor M4target
HyoscyamineAdenylate cyclase type 1target
AtropineMuscarinic acetylcholine receptor M2target
AtropineMuscarinic acetylcholine receptor M1target
AtropineMuscarinic acetylcholine receptor M4target
AtropineMuscarinic acetylcholine receptor M5target
AtropineMuscarinic acetylcholine receptor M3target
AtropineGlycine receptor subunit alpha-1target
AtropineNeuronal acetylcholine receptor subunit alpha-4target
AtropineNeuronal acetylcholine receptor subunit beta-2target
AtropineBile salt export pumptransporter
ScopolamineMuscarinic acetylcholine receptor M1target
ScopolamineSucrase-isomaltase, intestinaltarget
ScopolamineMuscarinic acetylcholine receptor M2target
ScopolamineMuscarinic acetylcholine receptor M3target
ScopolamineMuscarinic acetylcholine receptor M4target
ScopolamineMuscarinic acetylcholine receptor M5target
ScopolamineNeuronal acetylcholine receptor subunit alpha-4target
ScopolamineNeuronal acetylcholine receptor subunit beta-2target
ScopolamineCytochrome P450 3A4enzyme