refractory, metastatic Breast cancer (DBCOND0023213)
Identifiers
- Synonyms
- Refractory Metastatic breast cancer / Refractory, metastatic Breast Cancer
Associated Data
- Indicated Drugs and Targets
Drug Description Targets Eribulin A microtubule inhibitor used to treat metastatic breast cancer and metastatic or unresectable liposarcoma.- Apoptosis regulator Bcl-2target
- Tubulin beta-1 chaintarget
Lapatinib An antineoplastic agent and tyrosine kinase inhibitor used for the treatment of advanced or metastatic HER-positive breast cancer in patients who received prior chemotherapeutic treatments.- Epidermal growth factor receptortarget
- Receptor tyrosine-protein kinase erbB-2target
- Cytochrome P450 3A4enzyme
- Cytochrome P450 2C8enzyme
- ATP-dependent translocase ABCB1transporter
- Antigen peptide transporter 1transporter
- Cytochrome P450 3A5enzyme
- Cytochrome P450 2C19enzyme
Palbociclib An endocrine-based chemotherapeutic agent used in combination with other antineoplastic agents to treat HER2-negative and HR-positive advanced or metastatic breast cancer.- Cyclin-dependent kinase 4target
- Cyclin-dependent kinase 6target
- Cytochrome P450 3A4enzyme
- Sulfotransferase 2A1enzyme
- ATP-dependent translocase ABCB1transporter
- Broad substrate specificity ATP-binding cassette transporter ABCG2transporter
- Albumincarrier
- Solute carrier family 22 member 1transporter
- Clinical Trials
- Not Available