NCT05681598
Hydroxyurea Treatment for Adult Sickle Cell Anemia Patients in Kinshasa No drug interventions treatment Not Available completed NCT05660265
A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Oral GSK4172239D Compared With Placebo in Sickle Cell Disease Participants Aged 18 to 50 Years No drug interventions treatment 1 recruiting NCT05087303
Telemedicine for Children With Sickle Cell Disease No drug interventions health_services_research Not Available recruiting NCT02187003
Efficacy and Safety of Rivipansel (GMI-1070) in the Treatment of Vaso-Occlusive Crisis in Hospitalized Subjects With Sickle Cell Disease No drug interventions treatment 3 completed NCT00005703
Hemostasis in Sickle Cell Disease--Infancy to Adulthood No drug interventions Not Available Not Available completed NCT01566890
Microvascular Blood Flow in Sickle Cell Anemia No drug interventions diagnostic Not Available completed NCT05457790
Feasibility and Preliminary Efficacy of Acceptance and Commitment Therapy (ACT) for Sleep Disturbances in Adults With Sickle Cell Disease (SCD) No drug interventions supportive_care Not Available recruiting NCT02675790
Moderate Dose Hydroxyurea for Secondary Stroke Prevention in Children With Sickle Cell Disease in Sub-Saharan Africa No drug interventions prevention 3 completed NCT00538564
Tadalafil for Treatment of Priapism in Men With Sickle Cell Anemia No drug interventions prevention 2 withdrawn NCT00512564
Clinical and Laboratory Assessment of Iron Overload in Sickle Cell Anemia and Sickle Cell Thalassemia No drug interventions Not Available Not Available completed NCT01137721
State Of The Art Functional Imaging In Sickle Cell Disease No drug interventions Not Available Not Available completed NCT00456443
Invasive Infections in Children With Hemoglobinopathies No drug interventions Not Available Not Available completed NCT00004143
Allogeneic Mixed Chimerism Stem Cell Transplant Using Campath for Hemoglobinopathies & Bone Marrow Failure Syndromes No drug interventions treatment 2 completed NCT00094887
Nitric Oxide Inhalation to Treat Sickle Cell Pain Crises No drug interventions treatment 2 completed NCT02394587
MBSR for Pain Catastrophizing in SCD No drug interventions supportive_care Not Available completed NCT04400487
Actigraphy Improvement With Voxelotor (ActIVe) Study treatment 4 completed NCT01531387
Sparing Conversion to Abnormal TCD (Transcranial Doppler) Elevation (SCATE) prevention 3 terminated NCT02636387
Desmopressin as a Therapy for Bedwetting in Children With Sickle Cell Disease Not Available Not Available terminated NCT00360087
A Study of Patients Having Pulmonary Hypertension Associated With Sickle Cell Disease and Completing an ASSET Study No drug interventions treatment 3 terminated NCT00056433
Evaluation of Hydroxyurea Plus L-arginine or Sildenafil to Treat Sickle Cell Anemia No drug interventions treatment 1 completed NCT03380351
Specifying Interventions From the Sickle Cell Disease Implementation Consortium (SCDIC) No drug interventions Not Available Not Available completed NCT04476277
Red Cell Half Life Determination in Patients With and Without Sickle Cell Disease basic_science 0 completed NCT02372877
Evaluation of the AMICUS RBCx System in Sickle Cell Patients No drug interventions treatment Not Available completed NCT02843347
STRIDE Biorepository No drug interventions Not Available Not Available unknown_status NCT04351698
SMILES: Study of Montelukast in Sickle Cell Disease treatment 2 / 3 recruiting NCT02990598
Hydoxyurea Exposure in Lactation A Pharmacokinetics Study (HELPS) No drug interventions Not Available Not Available completed NCT00004797
Pilot Study of Fructose for Sickle Cell Crisis No drug interventions treatment Not Available completed NCT02326597
Decision Aid for Therapeutic Options In Sickle Cell Disease No drug interventions health_services_research Not Available completed NCT00072761
Silent Cerebral Infarct Transfusion Multi-Center Clinical Trial No drug interventions treatment 3 completed NCT00034528
Stem Cell Transplantation After Reduced-Dose Chemotherapy for Patients With Sickle Cell Disease or Thalassemia No drug interventions treatment 2 terminated NCT00236093
Extension Study of ACTIQ Treatment for Children and Adolescents With Breakthrough Pain No drug interventions treatment 2 completed NCT00059293
Transcranial Doppler (TCD) Ultrasound of Subjects Enrolled in BABY HUG - Ancillary to BABY HUG No drug interventions Not Available Not Available completed NCT00037388
Pediatrics:Chlamydia, Sickle Cell Anemia and Stroke Risk - Ancillary to STOP II No drug interventions Not Available Not Available completed NCT00735488
Sickle Cell Anemia Screening and Prevention in Northern Israel No drug interventions Not Available Not Available completed NCT00125788
L-Glutamine Therapy for Sickle Cell Anemia and Sickle ß0 Thalassemia No drug interventions treatment 2 completed NCT01425307
Transcranial Doppler (TCD) With Transfusions Changing to Hydroxyurea prevention 3 terminated NCT04800809
The Afolabi Stroke Registry for Children and Young Adults With SCD in Northern Nigeria No drug interventions Not Available Not Available completed NCT00586209
L-Glutamine Therapy for Sickle Cell Anemia treatment 2 terminated NCT04420585
Desmopressin for Bedwetting in Children With SCD treatment 4 terminated NCT00004485
Bone Marrow Transplantation in Treating Children With Sickle Cell Disease No drug interventions treatment 1 / 2 completed NCT03128515
Optimizing Hydroxyurea Therapy in Children With SCA In Malaria Endemic Areas treatment 3 completed NCT02657837
Measures of Respiratory Health (MRH) No drug interventions Not Available Not Available recruiting NCT03114137
Heart Arteries and Sickle Cell Disease / Coeur Artères DREpanocytose No drug interventions Not Available Not Available unknown_status NCT01350232
Treatment of Sickle Cell Anemia With Stem Cell Transplant treatment Not Available terminated NCT04255875
Dose Escalation Study of PF-07209326 in Healthy Participants and Participants With Sickle Cell Disease No drug interventions basic_science 1 completed NCT01441375
Sickle Cell Disease: A Retrospective Chart Review No drug interventions Not Available Not Available completed NCT00981370
Clinical Importance of Treating Iron Overload in Sickle Cell Disease treatment 3 terminated NCT01758042
Bone Marrow and Kidney Transplant for Patients With Chronic Kidney Disease and Blood Disorders No drug interventions treatment Not Available recruiting NCT02530242
Carbon Monoxide Measurement to Screen for Sickle Cell Disease No drug interventions diagnostic Not Available completed NCT01178099
An Assessment of Prasugrel on Healthy Adults and Sickle Cell Adults basic_science 1 completed NCT02556099
EXTEND EXpanding Treatment for Existing Neurological Disease treatment 2 active_not_recruiting NCT06144749
A Safety, Efficacy, and Pharmacokinetic (PK) Study of HBI-002, an Oral Carbon Monoxide (CO) Therapeutic, in Subjects With Sickle Cell Disease (SCD) No drug interventions treatment 1 / 2 not_yet_recruiting NCT05675436
Investigating the Mechanistic Effects of Mitapivat in Subjects With Sickle Cell Disease No drug interventions Not Available Not Available enrolling_by_invitation NCT04406818
Metabolic and Hemodynamic Reserve in Pediatric SCA basic_science Not Available recruiting NCT03006718
SCD-PROMIS: A Software Platform to Enhance Self-efficacy and Patient-provider Engagement for Patients With Sickle Cell Pain No drug interventions other Not Available completed NCT00850018
Examining Cognitive Function and Brain Abnormalities in Adults With Sickle Cell Disease - Pilot Intervention Study No drug interventions treatment 1 completed NCT03926819
A Study to Assess the Safety and Pharmacokinetics of HBI-002, an Oral Carbon Monoxide Therapeutic, in Healthy Volunteers No drug interventions treatment 1 completed NCT02373241
Preventing Sickle Cell Kidney Disease treatment 2 terminated NCT06016634
Alendronate for Osteonecrosis in Adults With Sickle Cell Disease treatment 2 recruiting NCT01976416
Novel Use Of Hydroxyurea in an African Region With Malaria treatment 3 completed NCT02090296
Risk-based Therapy for Sickle Cell Anemia: A Feasibility Study prevention 2 withdrawn NCT00890396
Long-Term Effects of Hydroxyurea in Children With Sickle Cell Anemia (The BABY HUG Follow-up Study) Not Available Not Available completed NCT00023296
Nitric Oxide and Transfusion Therapy for Sickle Cell Patients With Pulmonary Hypertension No drug interventions treatment 1 completed NCT02065596
Hematopoietic Stem Cell Transplant for Sickle Cell Disease treatment 1 completed NCT02433158
Safety of Rivipansel (GMI-1070) in the Treatment of One or More Vaso-Occlusive Crises in Hospitalized Subjects With Sickle Cell Disease treatment 3 terminated NCT00578435
Allogeneic Bone Marrow Transplantation for the Treatment of Genetic Disorders of Erythropoiesis No drug interventions treatment 2 completed NCT00035763
Pain in Sickle Cell Epidemiologic Study No drug interventions Not Available Not Available completed NCT00313963
MAST - Magnesium for Sickle Cell Acute Crisis in Children No drug interventions treatment 3 completed NCT01479439
Losartan to Reverse Sickle Nephropathy treatment 2 completed NCT00542230
Blood Sampling for Research Related to Sickle Cell Disease No drug interventions Not Available Not Available recruiting NCT05283148
Sickle Cell Disease (SCD) Bone Pain Study No drug interventions diagnostic Not Available completed NCT04170348
Daily Vitamin D for Sickle-cell Respiratory Complications prevention 2 active_not_recruiting NCT02467257
Gum Arabic as Fetal Hemoglobin Agent in Sickle Cell Anemia No drug interventions treatment 1 / 2 completed NCT00512226
Iron Overload Assesment in Sickle Cell Anemia and Sickle Cell Thalassemia No drug interventions diagnostic Not Available completed NCT01589926
Bi-Level Positive Airway Ventilation for Acute Chest Syndrome No drug interventions supportive_care Not Available terminated NCT01800526
A Pilot Study of N-acetylcysteine in Patients With Sickle Cell Disease treatment 1 / 2 completed NCT00600665
Effectiveness of a Computerized Tool (PAINRelieveIt) to Help Manage Pain Related to Sickle Cell Disease No drug interventions supportive_care Not Available completed NCT00399074
Sulfadoxine- Pyrimethamine Versus Weekly Chloroquine for Malaria Prevention in Children With Sickle Cell Anemia No drug interventions prevention 3 completed NCT00599482
Far Infrared Radiation for Sickle Cell Pain Management No drug interventions supportive_care 1 unknown_status NCT00783627
Sickle Cell Disease and Endothelial Progenitor Cells (EPCs) No drug interventions Not Available Not Available completed NCT00005327
Prevention of Cerebral Infarction in Sickle Cell Anemia - Comprehensive Sickle Cell Center No drug interventions Not Available Not Available completed NCT01558076
Longitudinal Changes in Exercise Capacity in Children and Young Adults With Sickle Cell Anemia No drug interventions Not Available Not Available unknown_status NCT00736060
Clinical and Laboratory Characteristics of Sickle Cell Anemia Patients Admitted With Fever No drug interventions Not Available Not Available completed NCT01848691
Carbon Monoxide Monitor for the Measurement of End-Tidal Carbon Monoxide Levels in Children With or Without Hemolysis No drug interventions diagnostic Not Available completed NCT02022891
Systematic Psychological and Medical Care for Children With SCD No drug interventions Not Available Not Available completed NCT01482091
Intranasal Fentanyl for Initial Treatment of a Vaso-occlusive Crisis treatment 4 completed NCT00122980
Stroke With Transfusions Changing to Hydroxyurea No drug interventions prevention 3 terminated NCT00029380
Cord Blood Transplantation for Sickle Cell Anemia and Thalassemia No drug interventions treatment 2 completed NCT05169580
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of FTX-6058 No drug interventions treatment 1 recruiting NCT00067080
Safety of ICL670 vs. Deferoxamine in Sickle Cell Disease Patients With Iron Overload Due to Blood Transfusions No drug interventions treatment 2 completed NCT04208529
A Long-term Follow-up Study in Participants Who Received CTX001 other 3 enrolling_by_invitation NCT02981329
Fetal Hemoglobin Induction Treatment Metformin treatment 0 completed NCT00000592
Stroke Prevention in Sickle Cell Anemia (STOP 1) No drug interventions prevention 3 completed NCT04705792
Physical Rehabilitation in Sickle Cell Anemia No drug interventions treatment Not Available unknown_status NCT04536792
A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AG-946 in Healthy Volunteers and in Participants With Sickle Cell Disease No drug interventions treatment 1 completed NCT00937144
Endothelial Function in Patients With Sickle Cell Anemia Before and After Sildenafil No drug interventions treatment 4 withdrawn NCT00618644
Ranibizumab for Neovascularization in Sickle Cell Retinopathy No drug interventions treatment Not Available withdrawn NCT01601340
Effects of HQK-1001 in Patients With Sickle Cell Disease No drug interventions treatment 2 terminated NCT02672540
A Study of SANGUINATE for the Treatment of Vaso-occlusive Crisis (VOC) in Adult Sickle Cell Disease Patients No drug interventions treatment 2 completed NCT00735540
Clinical Diagnosis of Teenagers Admitted to Pediatric Departments No drug interventions Not Available Not Available completed NCT00519701
Hydroxyurea in Young Children With Sickle Cell Anemia No drug interventions prevention Not Available completed NCT01419704
Phase I/II Pilot Study of Mixed Chimerism to Treat Hemoglobinopathies No drug interventions treatment 1 / 2 withdrawn NCT00004404
Study of Clotrimazole and Hydroxyurea in Patients With Sickle Cell Syndromes No drug interventions treatment Not Available completed NCT02065869
Safety Study of Gene Modified Donor T-cells Following TCRαβ+ Depleted Stem Cell Transplant No drug interventions treatment 1 / 2 terminated NCT00276146
Dipyridamole/Magnesium To Improve Sickle Cell Hydration No drug interventions Not Available 2 withdrawn NCT02712346
The Role of Endothelin-1 in Sickle Cell Disease No drug interventions treatment 1 completed NCT00948012
Exercise-induced Pulmonary Hypertension in Patients With Sickle-cell Anemia No drug interventions Not Available Not Available completed NCT00004412
Phase II Randomized Trial:Arginine Butyrate Plus Standard Local Therapy in Patients With Refractory Sickle Cell Ulcers No drug interventions treatment 2 completed NCT04201210
A Trial to Assess Haploidentical T-depleted Stem Cell Transplantation in Patients With SCD No drug interventions treatment 2 recruiting NCT00009581
Nitric Oxide to Improve Blood Flow in Sickle Cell Disease No drug interventions treatment 2 completed NCT06250595
European Rare Blood Disorders Platform (ENROL) No drug interventions Not Available Not Available recruiting NCT01801423
Sickle Cell Disease - Stroke Prevention in Nigeria Trial No drug interventions treatment Not Available completed NCT00005438
Neuropsychological Studies of Children With Sickle Cell No drug interventions Not Available Not Available completed NCT03653338
T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other Anemias No drug interventions treatment 1 / 2 recruiting NCT00495638
Pulmonary Hypertension, Hypoxia and Sickle Cell Disease No drug interventions Not Available Not Available completed NCT05347043
The Montreal Cognitive Assessment.Test in Adults With Sickle Cell Disease No drug interventions screening Not Available unknown_status NCT00528203
Establishing a Repository of Blood and DNA Samples From People With Sickle Cell Disease (Comprehensive Sickle Cell Centers Collaborative Genotype-Phenotype Database and Sample Repository) No drug interventions Not Available Not Available terminated NCT01783990
Pediatric Hydroxyurea Phase III Clinical Trial (BABY HUG) Follow-up Observational Study II Protocol No drug interventions Not Available Not Available completed NCT00000602
Pediatric Hydroxyurea in Sickle Cell Anemia (PED HUG) No drug interventions treatment 2 completed NCT01905787
Sickle Cell Anemia - A Comparative Study Between Three Ethnical Communities, a Multicenter Study No drug interventions Not Available Not Available unknown_status NCT02286154
Therapeutic Response Evaluation and Adherence Trial (TREAT) No drug interventions treatment Not Available recruiting NCT00040677
A Study of the Efficacy and Safety of ICA-17043 (With or Without Hydroxyurea) in Patients With Sickle Cell Anemia. No drug interventions treatment 2 completed NCT00246077
Quality of Life of Children With Sickle Cell Disease Who Are Getting Chronic Transfusions With a Lifeport No drug interventions Not Available Not Available completed NCT00005277
Cooperative Study of The Clinical Course of Sickle Cell Disease No drug interventions Not Available Not Available completed NCT01522547
Study to Determine the Maximum Tolerated Dose, Safety and Effectiveness of Pomalidomide for Patients With Sickle Cell Disease No drug interventions treatment 1 completed NCT04011345
Folic Acid Supplementation in Children With Sickle Cell Disease No drug interventions supportive_care Not Available completed NCT02769845
SACRED A Prospective Research Study to Reduce Stroke in Children With Sickle Cell Anemia No drug interventions supportive_care Not Available active_not_recruiting NCT00971698
The Spleen in Sickle Cell Anemia and Sickle Cell Thalassemia No drug interventions Not Available Not Available completed NCT00669305
Bone Marrow for Hemoglobinopathy Research No drug interventions Not Available Not Available completed NCT02258997
Hepcidin Levels in Sickle Cell Disease (SCD) No drug interventions Not Available Not Available completed NCT00001197
Hydroxyurea for the Treatment of Patients With Sickle Cell Anemia No drug interventions treatment 2 completed NCT00005783
A Phase I/II Trial of Recombinant-Methionyl Human Stem Cell Factor (SCF) in Adult Patients With Sickling Disorders No drug interventions treatment 1 completed NCT00529061
Establishing a Database of People With Sickle Cell Disease (Comprehensive Sickle Cell Centers Collaborative Data Project [C-Data]) No drug interventions Not Available Not Available terminated NCT04584528
Implementing an Individualized Pain Plan (IPP) for ED Treatment of VOE's in Sickle Cell Disease No drug interventions treatment Not Available completed NCT00029393
Induction of Stable Chimerism for Sickle Cell Anemia No drug interventions treatment 2 completed NCT00005893
Study of Allogeneic Bone Marrow Transplantation Using Matched, Related Donors in Patients With Nonmalignant Hematologic Disorders No drug interventions treatment Not Available completed NCT01783093
Tricuspid Regurgitant Jet Velocity as an Independent Marker for Mortality in Sickle Cell Anemia No drug interventions Not Available Not Available completed NCT01547793
Carbon Monoxide Levels and Sickle Cell Disease Severity No drug interventions Not Available Not Available completed NCT03376893
Epidemiology of Silent and Overt Strokes in Sickle Cell Disease No drug interventions Not Available Not Available recruiting NCT04808778
Stroke Prevention in Young Adults With Sickle Cell Anemia No drug interventions Not Available Not Available active_not_recruiting NCT03634488
Management of Severe Acute Malnutrition in SCD, in Northern Nigeria No drug interventions treatment 2 completed NCT04001907
Effect of Exercise With and Without HMB on Body Composition and Muscle Strength in Sickle Cell Anaemia No drug interventions treatment Not Available unknown_status NCT04581356
Voxelotor Sickle Cell Exercise Study No drug interventions treatment 4 completed NCT01356485
Safety Study of MP4CO in Adult Sickle Cell Patients No drug interventions Not Available 1 completed NCT00000585
Penicillin Prophylaxis in Sickle Cell Disease (PROPS) No drug interventions prevention 3 completed NCT03020615
Hydroxyurea Management in Kids: Intensive Versus Stable Dosage Strategies No drug interventions treatment 2 completed NCT02149537
Risk Clinical Stratification of Sickle Cell Disease in Nigeria, Assessment of Efficacy/Safety of Hydroxyurea Treatment No drug interventions treatment 4 completed NCT04091737
CSL200 Gene Therapy in Adults With Severe Sickle Cell Disease No drug interventions treatment 1 terminated NCT00113152
Heart Disease in Sickle Cell Anemia No drug interventions Not Available Not Available completed NCT00006400
Hydroxyurea to Prevent Organ Damage in Children With Sickle Cell Anemia No drug interventions prevention 3 completed NCT00005300
Investigation of Selected Patient Groups From The Cooperative Study of Sickle Cell Disease No drug interventions Not Available Not Available completed NCT00448370
Role of Placenta Growth Factor in Sickle Acute Chest Syndrome No drug interventions Not Available Not Available completed NCT00530270
Dexamethasone to Treat Acute Chest Syndrome in People With Sickle Cell Disease No drug interventions treatment 3 terminated NCT01527799
Exercise Capacity in Pediatric Sickle Cell Anemia No drug interventions Not Available Not Available completed NCT04134299
To Assess Safety, Tolerability and Physiological Effects on Structure and Function of AXA4010 in Subjects With Sickle Cell Disease No drug interventions basic_science Not Available completed NCT06481306
A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease No drug interventions treatment 1 / 2 recruiting NCT02565849
Study of Ventilatory Mechanics in Patients With Sickle Cell Anemia No drug interventions Not Available Not Available completed NCT03733249
Long Term Follow-up Study for Patients Enrolled on the BP-004 Clinical Study No drug interventions treatment 1 / 2 terminated NCT00115336
Ketorolac Versus Ibuprofen to Treat Painful Episodes of Sickle Cell Disease No drug interventions treatment 4 terminated NCT02186418
Gene Transfer for Patients With Sickle Cell Disease No drug interventions supportive_care 1 / 2 terminated NCT02961218
Study of Efficacy, Safety and Tolerability of ACZ885 (Canakinumab) in Pediatric and Young Adult Patients With Sickle Cell Anemia No drug interventions treatment 2 completed NCT00294541
A Study Evaluating the Long-Term Safety of ICA-17043 in Sickle Cell Disease Patients With or Without Hydroxyurea Therapy No drug interventions treatment 3 terminated NCT00040417
Bone Marrow Transplant From Donor Using Less Toxic Conditioning for Patient With High Risk Hemoglobinopathies No drug interventions treatment 2 terminated NCT00513617
Effectiveness of Arginine as a Treatment for Sickle Cell Anemia No drug interventions treatment 2 completed NCT03397017
Transfusion Treatment in Patients With SCD No drug interventions Not Available Not Available completed NCT01179217
A Phase III Safety and Efficacy Study of L-Glutamine to Treat Sickle Cell Disease or Sickle βo-thalassemia No drug interventions treatment 3 completed NCT02497924
A Study of the Absorption, Metabolism, and Excretion of GBT440 in Healthy Male Subjects No drug interventions other 1 completed NCT00001716
Effects of Nitric Oxide and Nitroglycerin in Patients With Sickle Cell Anemia No drug interventions treatment 2 completed NCT06078696
Siplizumab for Sickle Cell Disease Transplant No drug interventions treatment 1 / 2 recruiting NCT01316796
Topical Sodium Nitrite for Chronic Leg Ulcers in Adult Patients With Blood Disorders No drug interventions treatment 1 completed NCT06503458
A Low-Interventional Study of an Electronic Sickle Cell Disease Patient Reported Outcomes in Sickle Cell Participants No drug interventions Not Available Not Available terminated NCT00300235
Priapism in Boys and Men With Sickle Cell Disease - Demographics, Characteristics and Prevalence No drug interventions Not Available Not Available completed NCT05477563
Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease No drug interventions treatment 3 recruiting NCT00000586
Multicenter Study of Hydroxyurea in Patients With Sickle Cell Anemia (MSH) No drug interventions treatment 3 completed NCT04093986
Hydroxyurea Exposure Limiting Pregnancy and Follow-Up Lactation No drug interventions Not Available Not Available recruiting NCT02162225
Study of Beet Juice for Patients With Sickle Cell Anemia No drug interventions treatment 2 withdrawn NCT00006130
Decompression Coring Versus Conservative Therapy in Patients With Avascular Necrosis of the Hip Related to Sickle Cell Disease No drug interventions treatment Not Available completed NCT03069430
A Self-Management Intervention for Youth With Sickle Cell Disease and Their Families: Phase I No drug interventions Not Available Not Available completed NCT00011648
Secondary Pulmonary Hypertension in Adults With Sickle Cell Anemia No drug interventions Not Available Not Available completed NCT00005326
Cerebrovascular Involvement in Sickle Cell Disease - Comprehensive Sickle Cell Center No drug interventions Not Available Not Available completed NCT00480974
Long Term Follow up in Sickle Cell Patients Treated by Hydroxyurea No drug interventions Not Available Not Available completed NCT06529874
Pressure Pain Tolerance in Relation to Balance and Strength in Children No drug interventions other Not Available recruiting NCT00006182
Stroke Prevention in Sickle Cell Anemia (STOP 2) No drug interventions prevention 3 completed NCT00860782
Parent Educational Program for Children With Sickle Cell Disease No drug interventions supportive_care Not Available completed NCT05357482
Addition of JSP191 (C-kit Antibody) to Nonmyeloablative Hematopoietic Cell Transplantation for Sickle Cell Disease and Beta-Thalassemia No drug interventions treatment 1 / 2 recruiting NCT00029731
Arginine Treatment of Acute Chest Syndrome (Pneumonia) in Sickle Cell Disease Patients No drug interventions treatment 2 completed NCT03249831
A Blood Stem Cell Transplant for Sickle Cell Disease No drug interventions treatment 1 active_not_recruiting NCT01788631
A Phase II Trial of Regadenoson in Sickle Cell Anemia No drug interventions treatment 2 completed NCT01894594
Efficacy, Safety Study and Benefit of Alkali Therapy in Sickle Cell Disease No drug interventions treatment 1 terminated NCT03789591
Hydroxyurea Optimization Through Precision Study No drug interventions prevention 3 recruiting NCT00977691
Haploidentical PBMC Transplant for Severe Congenital Anemias No drug interventions treatment 1 / 2 active_not_recruiting NCT00971880
Blood Transfusions in Thalassemia Patients, Complications and Adverse Effects No drug interventions Not Available Not Available completed NCT02813629
tDCS Associated With Peripheral Electrical Stimulation for Pain Control in Individuals With Sickle Cell Disease No drug interventions treatment 2 unknown_status NCT00672789
Adherence to Hydroxyurea in Children With Sickle Cell Anemia No drug interventions health_services_research Not Available completed NCT00004492
Phase I/II Randomized Study of Hydroxyurea With or Without Clotrimazole in Patients With Sickle Cell Anemia No drug interventions treatment 1 / 2 completed NCT01931644
At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions No drug interventions Not Available Not Available completed NCT02445144
Establishment of Functional MRI Imaging Parameters for Use in the Evaluation of Sickle Cell Disease No drug interventions Not Available Not Available terminated NCT01506544
Pharmacokinetics (PK) of Liquid Hydroxyurea in Pediatric Patients With Sickle Cell Anemia No drug interventions Not Available 1 completed NCT05451940
Hydroxyurea and EPO in Sickle Cell Disease No drug interventions treatment 1 / 2 recruiting NCT00005467
Indices of Severity and Prognosis for Sickle Cell Disease No drug interventions Not Available Not Available completed NCT00840567
Skin and Blood Research Samples From Healthy Volunteers and Patients With Hematologic Diseases No drug interventions basic_science Not Available terminated NCT03062501
Hydroxyurea in the Emergency Room to Lessen Pain in Sickle Cell Crisis No drug interventions treatment 2 unknown_status NCT00528801
Examining Cognitive Function and Brain Abnormalities in Adults With Sickle Cell Disease No drug interventions Not Available Not Available completed NCT01925001
Phase 2 Study of MP4CO to Treat Vaso-occlusive Sickle Crisis No drug interventions treatment 2 withdrawn NCT06290401
A Socio-ecological Approach for Improving Self-management in Adolescents With SCD No drug interventions treatment 2 not_yet_recruiting NCT01703104
The Efficacy of Jobelyn (Sorghum Bicolor Extract)in the Treatment of Sickle Cell Anemia No drug interventions treatment 1 / 2 completed NCT01340404
Allogeneic Genoidentical Stem Cell Transplantation in Children With Sickle-cell Anemia and Cerebral Vasculopathy No drug interventions treatment Not Available completed NCT00874172
Effectiveness of New Analgesic Strategy Compared to the Usal Antalgic Strategy No drug interventions treatment Not Available completed NCT00143572
Use of Hydroxyurea and Magnesium Pidolate for Treatment of Sickle Cell Disease No drug interventions treatment 1 completed NCT00095472
Therapeutic Application of Intravascular Nitrite for Sickle Cell Disease No drug interventions treatment 1 completed NCT02072668
The Effect of Rivaroxaban in Sickle Cell Disease No drug interventions treatment 2 completed NCT01054768
Antioxidant Therapy to Reduce Inflammation in Sickle Cell Disease No drug interventions treatment 2 completed NCT01092169
Prevalence Of Microalbuminuria Among Children Suffering From Sickle Cell Nephropathy and Sickle Cell/Beta-Thalassemia No drug interventions Not Available Not Available unknown_status NCT01322269
A Study of HQK-1001 in Patients With Sickle Cell Disease No drug interventions treatment 2 completed NCT00040469
Bone Marrow Transplant From Related Donor for Patients With High Risk Hemoglobinopathies No drug interventions treatment 2 terminated NCT02561312
Comparison of Two Methods of Transfusion for Stroke Prevention in Sickle Cell No drug interventions Not Available Not Available completed NCT03442114
Shared-Decision Making for Hydroxyurea No drug interventions health_services_research Not Available unknown_status NCT01000155
Efficacy of Vorinostat to Induce Fetal Hemoglobin in Sickle Cell Disease No drug interventions treatment 2 terminated NCT01167023
Prasugrel Versus Placebo in Adult Sickle Cell Disease No drug interventions treatment 2 completed NCT02857023
Feasibility and Efficacy of a Home-based, Computerized Cognitive Training Program in Pediatric Sickle Cell Disease No drug interventions treatment Not Available completed NCT02411708
Study of SANGUINATE™ In the Treatment of Sickle Cell Disease Patients With Vaso-Occlusive Crisis No drug interventions treatment 2 completed NCT00131508
Trial of Oral Glutamine in Patients With Sickle Cell Anemia No drug interventions prevention 2 terminated NCT00004408
Phase III Randomized Study of Poloxamer 188 for Vaso-Occlusive Crisis of Sickle Cell Disease No drug interventions treatment 3 completed NCT02004808
Neutrophil Extracellular Traps and Sickle Cell Disease No drug interventions Not Available Not Available unknown_status NCT00415727
Prevention Of Morbidity In Sickle Cell Disease Pilot Phase No drug interventions Not Available 2 unknown_status NCT02844673
Mobile-Directly Observed Therapy on Adherence to Hydroxyurea No drug interventions treatment 2 completed