Pleural Mesotheliomas (DBCOND0029910)

Identifiers

Synonyms
Mesothelioma of Pleura / Mesothelioma; Pleura / Pleura Mesothelioma / Mesotheliomas Pleural / Pleural Mesothelioma / Malignant Pleural Mesothelioma / Malignant mesothelioma of pleura (disorder) / Pleural mesothelioma malignant

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Raltitrexed
A folate analog thymidylate synthase inhibitor used in the treatment of advanced colorectal cancer.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT05598268
A Study of T3011 Administered Via Intravenously in Patients With Advanced Solid Tumors.treatment1 / 2recruiting
NCT03907852
Phase 1/2 Trial of Gavo-cel (TC-210) in Patients With Advanced Mesothelin-Expressing Cancertreatment1 / 2active_not_recruiting
NCT04300244
Nivolumab and Ipilimumab +/- UV1 Vaccination as Second Line Treatment in Patients With Malignant Mesotheliomatreatment2active_not_recruiting
NCT06477419
A Study of Sacituzumab Govitecan in People With Mesotheliomatreatment2recruiting
NCT04115111
Diadem to Investigate the Activity and Safety of Durvalumabtreatment2completed
NCT06581549
Immune Microenvironment and Gene Expression Profiling in MesotheliomaNo drug interventionsNot AvailableNot Availablerecruiting
NCT05500508
Oral AMXT 1501 Dicaprate in Combination with IV DFMOtreatment1 / 2active_not_recruiting
NCT04214015
A Pilot Study to Explore the Role of Gut Flora in Metastatic MesotheliomaNo drug interventionsNot AvailableNot Availableunknown_status
NCT04996017
Atezolizumab Versus Placebo for the Adjuvant Treatment of Malignant Pleural Mesothelioma (Atezomeso)treatment3unknown_status
NCT03475953
A Phase I/II Study of Regorafenib Plus Avelumab in Solid Tumorstreatment1 / 2recruiting
NCT03054298
CAR T Cells in Mesothelin Expressing CancersNo drug interventionstreatment1completed
NCT03760575
Pembrolizumab in Combination With Chemotherapy and Image-Guided Surgery for Malignant Pleural Mesothelioma (MPM)treatment1recruiting
NCT05278975
Study of RSO-021 in Patients With Malignant Pleural Effusion Due to Advanced/Metastatic Solid Tumors Including Mesotheliomatreatment1 / 2recruiting
NCT05451849
A Phase 1/2 Trial of TC-510 In Patients With Advanced Mesothelin-Expressing Cancertreatment1 / 2active_not_recruiting
NCT06451536
Ga-68 FAPI PET Before ImmunotherapyNo drug interventionsdiagnosticNot Availablerecruiting
NCT04400539
The IMmunotherapy Pleural 5-ALA PDTtreatment2recruiting
NCT04287829
Pembrolizumab Plus Lenvatinib In Second Line and Third Line Malignant Pleural mesotheLioma Patientstreatment2active_not_recruiting
NCT05304208
dENdritic Cell Therapy Combined With SURgEry in MesotheliomaNo drug interventionstreatment1recruiting
NCT00037817
Phase I Study of Gene Induction Mediated by Sequential Decitabine/Depsipeptide Infusion With or Without Concurrent Celecoxib in Subjects With Pulmonary and Pleural Malignanciestreatment1completed
NCT05538806
TTFields in General Routine Clinical Care in Patients with Pleural Mesothelioma StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT05714553
NUC-3373 in Combination With Other Agents in Patients With Advanced Solid Tumourstreatment1 / 2recruiting
NCT06155279
Induction Chemo+immunotherapy in Resectable Epithelioid and Biphasic Pleural Mesothelioma (CHIMERA Study)treatment2not_yet_recruiting
NCT06362369
A Study of Oral 7HP349 (Alintegimod) in Combination with Ipilimumab Followed by Nivolumab Monotherapytreatment1 / 2recruiting
NCT00165503
Pleurectomy/Decortication With Intraoperative Intrathoracic/Intraperitoneal Heated Cisplatin With Sodium Thiosulfatediagnostic2terminated
NCT02414945
TILs & Low-Dose IL-2 Therapy Following Cyclophosphamide and Fludarabine in Pleural Mesothelioma Patientstreatment1 / 2completed
NCT04430842
Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072SNo drug interventionstreatment1completed
NCT00165516
Extrapleural Pneumonectomy With Intraoperative Intrathoracic/Intraperitoneal Heated Cisplatin With Amifostine and Sodium Thiosulfatetreatment2completed
NCT01160458
Phase II Study of IMC-A12 in Patients With Mesothelioma Who Have Been Previously Treated With Chemotherapytreatment2completed
NCT00895648
Pemetrexed (ALIMTA) Plus Cisplatin Followed by Surgery and Radiation Therapy for Mesotheliomatreatment2terminated
NCT02707666
A Pilot Window-Of-Opportunity Study of the Anti-PD-1 Antibody Pembrolizumab in Patients With Resectable Malignant Pleural Mesotheliomatreatment1terminated
NCT05930665
Study of Cadonilimab Combined With Bevacizumab and Standard Chemotherapy as First Line Therapy in Unresectable Pleural Mesotheliomatreatment2recruiting
NCT04040231
Using a Targeted Cancer Vaccine (Galinpepimut-S) With Immunotherapy (Nivolumab) in Mesotheliomatreatment1active_not_recruiting
NCT02585362
Whey Protein Supplement in Combination With Physical Exercise and Nutrition ProgramNo drug interventionssupportive_careNot Availablecompleted
NCT05086692
A Beta-only IL-2 ImmunoTherapY Studytreatment1 / 2recruiting
NCT05910112
Prospective Data Collection on Clinical, Radiological and Patient Reported Outcomes After Pleural InterventionNo drug interventionsNot AvailableNot Availablerecruiting
NCT02899195
Phase II MEDI4736 in Combination With Chemotherapy for First-Line Treatment of Unresectable Mesotheliomatreatment2completed
NCT00859495
Trimodal Lung-Sparing Treatment of Pleural Mesotheliomatreatment2terminated
NCT03210298
International Registry of Patients Treated With Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC)No drug interventionsNot AvailableNot Availableunknown_status
NCT04914897
A Study of SAR444245 Combined With Other Anticancer Therapies for the Treatment of Participants With Lung Cancer or Mesothelioma (Pegathor Lung 202)treatment2active_not_recruiting
NCT05077111
A Comparative Study Between Regional Anesthesia in Thoracoscopes and the Conventional General AnesthesiaNo drug interventionssupportive_care4unknown_status
NCT04324437
eRAPID: Online Symptom Reporting in Lung CancerNo drug interventionsotherNot Availablecompleted
NCT04334759
DuRvalumab With chEmotherapy as First Line treAtment in Advanced Pleural Mesotheliomatreatment3active_not_recruiting
NCT04823741
Molecular, Pathologic Intra Tumoral Heterogeneity in Malignant Pleural MesotheliomaNo drug interventionsNot AvailableNot Availablerecruiting
NCT05337735
A Phase II Clinical Trial to Evaluate Safety and Efficacy of XmAb20717 in Advanced Rare Cancerstreatment2suspended
NCT06410625
Evaluation of Response by FLT PET in MesotheliomaNo drug interventionsdiagnosticNot Availablerecruiting
NCT06416930
Study of Cadonilimab Combined With Chemotherapy in Recurrent / Refractory Pleural Mesotheliomatreatment2not_yet_recruiting
NCT02588131
A Study of Tremelimumab Combined With the Anti-PD-L1 MEDI4736 Antibody in Malignant Mesothelioma (NIBIT-MESO-1)treatment2unknown_status
NCT04106973
Mesothelioma Early Detection by VOCsNo drug interventionsNot AvailableNot Availableterminated
NCT05628376
TRAcking Thoracic Cancer Evolution Through Therapy (Rx) EVONo drug interventionsNot AvailableNot Availablerecruiting
NCT00299962
Gene Therapy for Pleural Malignanciestreatment1completed
NCT04042480
A Study of SGN-CD228A in Advanced Solid TumorsNo drug interventionstreatment1terminated
NCT00165555
Pleurectomy/Decortication Followed by Intrathoracic/Intraperitoneal Heated Cisplatin for Malignant Pleural Mesotheliomatreatment1completed