Bile Duct Cancer (DBCOND0032251)

Identifiers

Synonyms
Cancer of Bile Duct / Cancer of the Bile Duct / Biliary Cancer / Bile Duct Carcinoma / Biliary Cancers / Cancer, Bile Duct / Bile Ductus Cancer / Biliary Tract Cancer / Biliary Tract Cancers / Cancer of the Biliary Tract / Biliary Tract Cancer (BTC) / Bile duct cancer / Bile duct cancer NOS / Cholangiocarcinoma (morphologic abnormality) / Carcinoma bile duct / Malignant neoplasm of biliary tract, unspecified / Malignant tumor of biliary tract (disorder) / Malignant neoplasm of biliary tract, part unspecified / Bile duct adenocarcinoma / Intrahepatic bile duct carcinoma / Cholangiosarcoma / Cholangiocarcinoma NOS / Cholangiocarcinoma of biliary tract (disorder) / Cholangiocarcinoma

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Uracil
An antineoplastic agent used in combination with tegafur to treat various cancers, including breast, prostate, and liver cancer.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT06453590
Treatment of Distal Malignant Biliary Obstruction by Uncovered, Partially Covered, or Fully Covered Metal StentsNo drug interventionstreatmentNot Availablerecruiting
NCT04298021
DDR-Umbrella Study of DDR Targeting Agents in Advanced Biliary Tract CancerNo drug interventionstreatment2active_not_recruiting
NCT02954302
Proximal Roux-en-y Gastrojejunal Anastomosis on Delayed Gastric Emptying After Pylorus-resecting PancreaticoduodenectomyNo drug interventionspreventionNot Availableunknown_status
NCT02446379
Use of the EnLightTM and LightPathTM Imaging Systems in Gastrointestinal Tumour SurgeryNo drug interventionsNot AvailableNot Availablewithdrawn
NCT06274879
Safety of Biliary Intraductal Radiofrequency Ablation in Patients With Unresectable Extrahepatic Biliary Tract CancerNo drug interventionstreatment2not_yet_recruiting
NCT03602079
Study of A166 in Patients With Relapsed/Refractory Cancers Expressing HER2 Antigen or Having Amplified HER2 GeneNo drug interventionstreatment1 / 2completed
NCT04907643
Virtual Reality for GI Cancer Pain to Improve Patient Reported OutcomesNo drug interventionssupportive_careNot Availablerecruiting
NCT01256047
Effects of Preoperative Immunonutrition in Patients Undergoing HepatectomyNo drug interventionsprevention4completed
NCT04404647
Irreversible Electroporation of Unresectable Liver TumorsNo drug interventionstreatmentNot Availablewithdrawn
NCT06175845
Endoscopic Radiofrequency Ablation for Unresectable CholangiocarcinomaNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT01151761
Phase II SBRT & Chemo for Unresectable Cholangiocarcinoma Followed by Liver Transplantationtreatment2terminated
NCT04014478
A Clinical Trial to Evaluate Safety and Efficacy of Endovascualr Denervation in Treatment of Cancer PainNo drug interventionstreatmentNot Availableunknown_status
NCT00779688
A Registry of Patients Undergoing Cellvizio Endomicroscopy and Endoscopic Retrograde Cholangiopancreatography(ERCP) Imaging Procedures for Diagnosing Pancreatic and Bile Duct CancersNo drug interventionsNot AvailableNot Availablecompleted
NCT01438385
Interventional Endoscopy Database for Pancreatico-biliary, Gastrointestinal and Esophageal DisordersNo drug interventionsNot AvailableNot Availableunknown_status
NCT03111732
Pembrolizumab, a Monoclonal Antibody Against PD-1, in Combination With Capecitabine and Oxaliplatin (CAPOX) in People With Advanced Biliary Tract Carcinoma (BTC)treatment2completed
NCT06076252
Modified vs Conventional Blumgart Anastomosis of LPD for the Effects of Pancreatic Fistula of Periampullary CarcinomaNo drug interventionstreatmentNot Availableenrolling_by_invitation
NCT05655949
Y-90 With Durvalumab/Gem/Cis in Intrahepatic CholangioNo drug interventionstreatment2recruiting
NCT05858736
Safety, PK and Efficacy of AI-061 in Advanced Solid TumorsNo drug interventionstreatment1recruiting
NCT01755013
Photodynamic Therapy (PDT) for Palliation of CholangiocarcinomaNo drug interventionssupportive_care2 / 3unknown_status
NCT04152018
Study of PF-06940434 in Patients With Advanced or Metastatic Solid Tumors.No drug interventionstreatment1active_not_recruiting
NCT03951324
Volumetric Laser Endomicroscopy's (VLE) Diagnostic Accuracy Validation Study: Impact on Clinical Management StudyNo drug interventionsNot AvailableNot Availableunknown_status
NCT04104230
Quebec Pancreas Cancer StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT06043466
A Clinical Trial Targeting CEA Chimeric Antigen Receptor T (CAR-T) for CEA Positive Advanced Malignant Solid TumorsNo drug interventionstreatment1recruiting
NCT04596865
Recurrence After Whipple's (RAW) StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT05706974
Looking At Bile Duct Cancer Patient Experience Patterns in Medical TrialsNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT06340620
EUS Examination Using EndoSound Vision System vs. Standard EchoendoscopeNo drug interventionsdiagnosticNot Availablerecruiting
NCT04476082
Nutrition in Gastrointestinal TumorsNo drug interventionsNot AvailableNot Availablecompleted
NCT01522573
T-EUS for Gastrointestinal Disorders: A Multicenter RegistryNo drug interventionsNot AvailableNot Availableunknown_status
NCT01134276
Comparison Between Internal and External Preoperative Biliary Drainage in Periampullary CancersNo drug interventionstreatmentNot Availablecompleted
NCT05000294
Atezolizumab Plus Tivozanib in Immunologically Cold Tumor TypesNo drug interventionstreatment1 / 2recruiting
NCT02375880
Study of DKN-01 and Gemcitabine/Cisplatin in Patients With Carcinoma to Primary to the Intra- or Extra-Hepatic Biliary System or GallbladderNo drug interventionstreatment1completed
NCT05849480
A Study of CDX-1140, a CD40 Agonist, in Combination With Capecitabine and Oxaliplatin (CAPOX) and Keytruda in Subjects With Biliary Tract Carcinoma (BTC)No drug interventionstreatment1 / 2recruiting
NCT04660929
CAR-macrophages for the Treatment of HER2 Overexpressing Solid TumorsNo drug interventionstreatment1active_not_recruiting
NCT02628067
Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-158/KEYNOTE-158)No drug interventionstreatment2recruiting
NCT00183846
Study of Irinotecan Administered as a Continuous Infusion and Radiation Therapy for Upper Gastrointestinal Cancerstreatment1completed
NCT04383210
Study of Seribantumab in Adult Patients With NRG1 Gene Fusion Positive Advanced Solid TumorsNo drug interventionstreatment2active_not_recruiting
NCT00809081
Early Enteral Feeding After Pylorus Preserving PancreatoduodenectomyNo drug interventionstreatment3unknown_status
NCT05286814
M9241 in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer or Intrahepatic CholangiocarcinomaNo drug interventionstreatment2recruiting
NCT03763214
PTFE Stents for Treatment of Malignant Biliary StricturesNo drug interventionstreatmentNot Availableunknown_status
NCT00639314
Trial on the Evaluation of Pylorus-ring in PancreaticoduodenectomyNo drug interventionstreatmentNot Availablecompleted
NCT06256055
Phase 1 Study of UCMYM802 Injection in Mesothelin-positive Advanced Malignant Solid TumorsNo drug interventionstreatment1recruiting
NCT03788655
Metal Stents (Moving Cell Stent) for Inoperable Tumors of the Bile Duct TractNo drug interventionsNot AvailableNot Availableunknown_status
NCT04298008
AZD6738 Plus Durvalumab in Biliary Tract CancerNo drug interventionstreatment2recruiting
NCT05346484
A Study of CF33-hNIS (VAXINIA), an Oncolytic Virus, as Monotherapy or in Combination With Pembrolizumab in Adults With Metastatic or Advanced Solid TumorsNo drug interventionstreatment1recruiting
NCT04028479
The Registry of Oncology Outcomes Associated With Testing and TreatmentNo drug interventionsNot AvailableNot Availablerecruiting
NCT06048133
Study of Gemcitabine, Cisplatin, AB680 and AB122 During First Line Treatment of Advanced Biliary Tract Cancers (QUIC)No drug interventionstreatment2recruiting
NCT04566133
Combination of Trametinib (MEK Inhibitor) and Hydroxychloroquine (HCQ) (Autophagy Inhibitor) in Patients With KRAS Mutation Refractory Bile Tract Carcinoma (BTC).No drug interventionstreatment2terminated
NCT02821754
A Pilot Study of Combined Immune Checkpoint Inhibition in Combination With Ablative Therapies in Subjects With Hepatocellular Carcinoma (HCC) or Biliary Tract Carcinomas (BTC)No drug interventionstreatment2completed
NCT02028845
Loop-tipped Guidewire in Selective Biliary CannulationNo drug interventionstreatmentNot Availablecompleted
NCT01954745
Cabozantinib (XL-184) Monotherapy for Advanced CholangiocarcinomaNo drug interventionstreatment2completed
NCT01439698
Radio Frequency Ablation in the Management of Pancreatico-biliary Disorders: A Multicenter RegistryNo drug interventionsNot AvailableNot Availableunknown_status
NCT00356161
HAI Via Interventionally Implanted Port Catheter SystemsNo drug interventionstreatment2unknown_status
NCT04076761
Study of TRIFLURIDINE/TIPIRACIL in Previously Treated CholangiocarcinomaNo drug interventionstreatment2terminated
NCT03086993
Percutaneous Hepatic Perfusion vs. Cisplatin/Gemcitabine in Patients With Intrahepatic CholangiocarcinomaNo drug interventionstreatment2 / 3unknown_status
NCT05155878
Prognostic Factors in Periampullary Tumors and CystsNo drug interventionsNot AvailableNot Availablerecruiting
NCT05662488
FAPI PET for Response Evaluation and Prognosis Prediction in Liver and Biliary Cancer Patients Treated With PD-1 Combination TherapyNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT00280709
Biliary Metal Stent Study: Metal Stents for Management of Distal Malignant Biliary ObstructionNo drug interventionstreatment4completed
NCT05712356
A Study of LSTA1 When Added to Standard of Care Versus Standard of Care Alone in Patients With Advanced Solid TumorsNo drug interventionstreatment2recruiting
NCT00832637
Gemcitabine, Oxaliplatin, Tarceva &/or Cisplatin in HCC & Biliary Tree Cancerstreatment2terminated
NCT05266300
Implementation and Quality Assurance of DPYD-genotyping in Patients Treated With Fluoropyrimidines.No drug interventionsNot AvailableNot Availablecompleted
NCT02841800
Intra-luminal Radiofrequency Ablation for Inoperable Malignant Biliary StenosisNo drug interventionstreatmentNot Availablecompleted
NCT04763642
The Comparison of Miniinvasive and Open Pancreaticoduodenectomy for Cancer Pancreaticobiliary ZoneNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT02012699
Integrated Cancer Repository for Cancer ResearchNo drug interventionsNot AvailableNot Availablerecruiting
NCT05519319
Safety and Efficacy of PDT vs RFA vs PDT+RFA for the Treatment of Extrahepatic CholangiocarcinomaNo drug interventionstreatmentNot Availablerecruiting
NCT04853017
A Study of ELI-002 in Subjects With KRAS Mutated Pancreatic Ductal Adenocarcinoma (PDAC) and Other Solid TumorsNo drug interventionstreatment1active_not_recruiting
NCT01256034
Effects of Preoperative Immunonutrition in Patients Undergoing PancreaticoduodenectomyNo drug interventionsprevention4completed
NCT06028724
A Study on the Prevalence of Clinically Useful Mutations in Solid Tumor Characterized by Next Generation Sequencing Methods on Liquid Biopsy Analysis (POPCORN)No drug interventionsNot AvailableNot Availablerecruiting
NCT00628186
Randomized Controlled Trial on Pancreatic Stent Tube in PancreaticoduodenectomyNo drug interventionstreatmentNot Availablecompleted
NCT04937322
Radio Frequency Ablation in the Management of Pancreatico-biliary Disorders: A Multicenter Registry.No drug interventionsNot AvailableNot Availablecompleted
NCT01640522
Comprehensive Electronic Cancer Support System for the Treatment of Cancer Related SymptomsNo drug interventionssupportive_careNot Availablecompleted
NCT01915225
Obtaining Solid Tumor Tissue From People Having Biopsy or Surgery for Certain Types of CancerNo drug interventionsNot AvailableNot Availablerecruiting
NCT05911425
Combined Treatment of Treated Bile Duct CancerNo drug interventionstreatment2not_yet_recruiting
NCT02591030
Safety and Efficacy of Modified Folfirinox Versus Gemcis in Bile Duct TumoursNo drug interventionstreatment2 / 3completed
NCT05277766
Intraperitoneal Aerosolized Nanoliposomal Irinotecan (Nal-IRI) in Peritoneal Carcinomatosis From Gastrointestinal CancerNo drug interventionstreatment1recruiting
NCT03475966
Improving Outcomes in Cancer Patients With a Nutritional and Physical Conditioning Prehabilitation ProgramNo drug interventionssupportive_careNot Availableunknown_status
NCT00579865
Quality Of Life in Patients With Malignant Biliary ObstructionNo drug interventionsNot AvailableNot Availablecompleted
NCT02853474
Early Palliative Care in Patients With Metastatic Upper Gastrointestinal Cancers Treated With First-line ChemotherapyNo drug interventionssupportive_care3completed
NCT00624182
Gemcitabine With Peptide Vaccine Therapy in Treating Patients With Bile Duct Cancertreatment1suspended
NCT06277531
Evaluation of diagnostiC Capacity of eccDNAs as Biomarkers in Indetermined biLiary Stricture(ECCBILE)No drug interventionsNot AvailableNot Availablerecruiting
NCT04993131
Liver Transplantation for Non-resectable Perihilar CholangiocarcinomaNo drug interventionstreatmentNot Availablerecruiting
NCT01111591
Cyclooxygenase-2 Inhibitor for Adjuvant Anticancer Effect in Patients With Biliary-pancreas Cancertreatment4unknown_status
NCT03058289
A Phase 1/2 Safety Study of Intratumorally Dosed INT230-6No drug interventionstreatment1 / 2completed
NCT03525067
Colonization of Bile Ducts and Postoperative Infectious Complications of PancreaticoduodenectomiesNo drug interventionsNot AvailableNot Availablecompleted
NCT04164069
Dasatinib for the Prevention of Oxaliplatin-Induced Neuropathy in Patients With Metastatic Gastrointestinal Cancer Receiving FOLFOX Chemotherapy With or Without BevacizumabNo drug interventionsprevention1active_not_recruiting
NCT01317069
A Randomized, Open, Prospective Clinical Research of Fluorouracil Implant to Improve Surgical Gallbladder Cancer and Bile Duct CancerNo drug interventionstreatment2unknown_status
NCT05418543
CH-EUS in Diagnosis of Inoperable Bile Duct TumorsNo drug interventionsdiagnosticNot Availableunknown_status
NCT01041612
Comparing Covered Self-expandable Metallic Stent (SEMS) Above/Across the Sphincter of OddiNo drug interventionssupportive_care4completed
NCT02115542
Single Agent Regorafenib in Refractory Advanced Biliary CancersNo drug interventionstreatment2completed
NCT05179824
Tempus Priority Study: A Pan-tumor Observational StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT00386516
Study to Test the Benefit and Safety of GM-CT-01 in Combination With 5-FU to Treat Bile Duct and Gall Bladder Cancertreatment2withdrawn
NCT03821025
Self-expandable Metal Stents Versus Multiple Plastic Stents for Palliation of Biliary ObstructionNo drug interventionstreatmentNot Availableunknown_status
NCT04480190
Neoadjuvant Therapy in Biliary AdenocarcinomaNo drug interventionstreatment1withdrawn
NCT02908451
A Study of AbGn-107 in Patients With Gastric, Colorectal, Pancreatic or Biliary CancerNo drug interventionstreatment1terminated
NCT00868998
GTX Regimen for Biliary Cancerstreatment2terminated
NCT01838109
Postoperative Oral Nutritional Supplementation After Major Gastrointestinal SurgeryNo drug interventionstreatmentNot Availablecompleted
NCT02930252
Covered Versus Uncovered SEMS for Palliation of Malignant Biliary Strictures.No drug interventionssupportive_careNot Availablecompleted
NCT02091141
My Pathway: A Study Evaluating Herceptin/Perjeta, Tarceva, Zelboraf/Cotellic, Erivedge, Alecensa, and Tecentriq Treatment Targeted Against Certain Molecular Alterations in Participants With Advanced Solid TumorsNo drug interventionstreatment2completed
NCT00948935
Study of Gemcitabine, Irinotecan and Panitumumab in Patients With Advanced and Metastatic Biliary Tract Adenocarcinomatreatment2completed
NCT01099631
IL-2 Expressing, Attenuated Salmonella Typhimurium in Unresectable Hepatic SpreadNo drug interventionstreatment1completed
NCT00924027
A Study of Patients Receiving High-Dose Rate BrachytherapyNo drug interventionstreatment2active_not_recruiting
NCT01401894
Perception Prognosis, Goals of Treatment, and CommunicationNo drug interventionsNot AvailableNot Availablecompleted
NCT06101277
Locally ablatIVe thErapy for oLigo-progressive gastrOintestiNal maliGnancies (LIVELONG)No drug interventionstreatmentNot Availablerecruiting
NCT01859728
GAMBIT Trial: Cisplatin Plus Irinotecan in the Treatment of Gallbladder or Biliary Tract CancerNo drug interventionstreatment2unknown_status
NCT05517811
Pre- and Post-operative TEG Indices in Patients With or Without Adenocarcinoma Undergoing Surgical ResectionNo drug interventionsNot AvailableNot Availablerecruiting
NCT01773785
Phase II Study of SPI-1620 in Combination With Docetaxel as a Second-Line to Treat Biliary CancerNo drug interventionstreatment2terminated
NCT01853618
Tremelimumab With Chemoembolization or Ablation for Liver CancerNo drug interventionstreatment1 / 2completed
NCT00551096
Gemcitabine/Capecitabine/ZD6474 in Advanced Solid Tumorstreatment1completed
NCT00626158
Gemcitabine and Capecitabine to Treat Patients With Advanced Pancreatic and Biliary Cancerstreatment1completed
NCT04517448
Quality of Life of Patients Over 75 Yars Undergoing Palliative ChemotherapyNo drug interventionsNot AvailableNot Availableunknown_status
NCT04644068
Study of AZD5305 as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid MalignanciesNo drug interventionstreatment1 / 2recruiting
NCT02626195
Preoperative Nutritional Support in Malnutritional Cancer PatientsNo drug interventionstreatmentNot Availablecompleted
NCT01661114
A Trial of Gemcitabine, Infusional 5-Fluorouracil and Cisplatin for Advanced Pancreatic and Biliary CancersNo drug interventionstreatment2completed
NCT02703714
Pembrolizumab and GM-CSF in Biliary CancerNo drug interventionstreatment2completed
NCT05462314
Intestinal Microbiome, Oral Microbiome, and Whole Blood Transcriptome Analyses in Gastrointestinal MalignanciesNo drug interventionsNot AvailableNot Availablerecruiting
NCT04740164
A Dual Channel Supraglottic Airway Device (LMA Gastro) for Oxygenation in Patients Undergoing ERCPNo drug interventionstreatmentNot Availablecompleted
NCT02611453
Cholangiography Using Carbon Dioxide Versus Iodinated Contrast in ERCPNo drug interventionsdiagnosticNot Availableactive_not_recruiting
NCT03507998
Phase 1 Dose Escalation Study of CGX1321 in Subjects With Advanced Gastrointestinal TumorsNo drug interventionstreatment1unknown_status
NCT00767234
Permission to Collect Blood Over Time for ResearchNo drug interventionsNot AvailableNot Availableterminated
NCT02451553
Afatinib Dimaleate and Capecitabine in Treating Patients With Advanced Refractory Solid Tumors, Pancreatic Cancer or Biliary CancerNo drug interventionstreatment1completed
NCT02204124
Whipple Procedure: Standard of Care vs. ThunderbeatNo drug interventionstreatmentNot Availableterminated
NCT03162510
Biweekly SOLAR, as First-line C/T in Pts With Gastric, Pancreatic and Biliary CancersNo drug interventionstreatment1completed
NCT03896958
The PIONEER Initiative: Precision Insights On N-of-1 Ex Vivo Effectiveness Research Based on Individual Tumor Ownership (Precision Oncology)No drug interventionsNot AvailableNot Availableunknown_status
NCT01016639
Study of Capecitabine and Oxaliplatin in Combination With Radiotherapy in Patients With Unresectable Gastro-Intestinal CancerNo drug interventionstreatment1 / 2completed
NCT01530503
Second Line Therapy in Advanced Biliary Tract CancerNo drug interventionstreatment2completed
NCT05297903
XmAb20717 in Advanced Biliary Tract CancersNo drug interventionstreatment2active_not_recruiting
NCT04642664
Apatinib Plus Camrelizumab in Patients With Previously Treated Advanced Biliary Tract CancerNo drug interventionstreatment2completed
NCT00955721
A Study of Combination of Gemcitabine, Oxaliplatin (GEMOX)-Sorafenib in Patients With Advanced Biliary Tract Cancertreatment1 / 2terminated
NCT04871321
Biomarker Discovery in Patients With Advanced Biliary Tract CancerNo drug interventionsNot AvailableNot Availablerecruiting
NCT02966821
Study of Surufatinib as Second-line Treatment in Patients With Biliary Tract CarcinomaNo drug interventionstreatment2completed
NCT06171321
Circulating Tumor DNA Guided Adjuvant Chemotherapy for Biliary Tract CarcinomaNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT02102984
Covered Versus Uncovered Biliary Stents for Biliary MalignanciesNo drug interventionstreatmentNot Availablecompleted
NCT01713387
A Phase I Study of Adjuvant Chemotherapy With GS in Biliary Tract Cancer Undergoing Resection Without Major HepatectomyNo drug interventionstreatment1completed
NCT04492033
A Study of CTX-009 (ABL001) in Combination With Irinotecan or Paclitaxel in Advanced or Metastatic Solid Tumor PatientsNo drug interventionstreatment1 / 2active_not_recruiting
NCT00423254
Safety and Immune Response to a Multi-component Immune Based Therapy (MKC1106-PP) for Patients With Advanced Cancer.No drug interventionstreatment1completed
NCT04779151
Basket Trial Exploring the Efficacy and Safety of the Combination of Niraparib and DostarlimabNo drug interventionstreatment2suspended
NCT04692051
A Phase II Study for Nab-paclitaxel Plus Cisplatin vs Gemcitabine Plus Cispatin as First Line Chemotherapy in Advanced Biliary Tract CancerNo drug interventionstreatment2unknown_status
NCT01180153
Study of S-1 Oxaliplatin (SOX) for Biliary Tract Cancer (BTC) (Ampullary Adenocarcinoma)treatment2unknown_status
NCT01811277
SOX Sequential S-1 in Advanced Biliary Tract Carcinoma(BTC)and Pancreatic CancerNo drug interventionstreatment2unknown_status
NCT05998447
GEN-001 Plus Pembrolizumab for Patients With Advanced Refractory Biliary Tract CancerNo drug interventionstreatment2recruiting
NCT06178445
Efficacy and Safety of GemCis Plus Trastuzumab Plus Pembrolizumab in Previously Untreated HER2-positive Biliary Tract CancerNo drug interventionstreatment2recruiting
NCT05723705
Impact of a European Training Program for Robotic Liver Surgery (LIVEROBOT)No drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT06017297
Neoadjuvant Tremelimumab and Durvalumab With Gem/Cis in Intrahepatic CholangiocarcinomaNo drug interventionstreatment2recruiting
NCT03818997
Combination of Targeted and Immunotherapy for Advanced Biliary Tract and Esophagogastric Gastric CancerNo drug interventionstreatment2withdrawn
NCT05012397
Milademetan in Advanced/Metastatic Solid TumorsNo drug interventionstreatment2terminated
NCT06451497
Phase 1 Trial of ZM008 as Single Agent and in Combination With Pembrolizumab in Patients With Advanced Solid TumorsNo drug interventionsother1recruiting
NCT03833661
M7824 Monotherapy in Locally Advanced or Metastatic Second Line (2L) Biliary Tract Cancer (Cholangiocarcinoma and Gallbladder Cancer)No drug interventionstreatment2completed
NCT01589328
Effect of Early Management on PAin and DEpression in Patients With PancreatoBiliary Cancer, EPADE-PBNo drug interventionssupportive_careNot Availablecompleted
NCT03110328
Study of Pembrolizumab in Metastatic Biliary Tract Cancer as Second-line Treatment After Failing to at Least One Cytotoxic Chemotherapy Regimen: Integration of Genomic Analysis to Identify Predictive Molecular Subtypestreatment2completed
NCT05222971
Olaparib With or Without Durvalumab for DDR Gene Mutated Biliary Tract Cancer Following Platinum-based ChemotherapyNo drug interventionstreatment2recruiting
NCT05156788
Tislelizumab(Anti PD-1), Lenvatinib and GEMOX Transformation in the Treatment of Potentially Resectable, Locally Advanced Biliary Tract CancerNo drug interventionstreatment2active_not_recruiting
NCT05520788
Ambispective Cohort Study of Precision Medicine for Primary Hepatobiliary Cancer Based on Next-generation SequencingNo drug interventionsNot AvailableNot Availablerecruiting
NCT00380588
Randomized Phase 2 Study With Gemcitabine Alone and Combination Therapy for Patients With Advanced Biliary Tract Cancertreatment2completed
NCT01815307
Phase II Study of Gemcitabine Versus S-1 Adjuvant Therapy After Hemihepatectomy for Biliary Tract CancerNo drug interventionstreatment2completed
NCT05942807
Observational Monocentric Study on Biliary Tract Cancer (BABEL)No drug interventionsNot AvailableNot Availablerecruiting
NCT06490107
Durvalumab Combined With S-1 as Adjuvant Therapy of Resectable BTCNo drug interventionstreatment2active_not_recruiting
NCT06428409
A Clinical Study of MK-2870 Alone or With Chemotherapy to Treat Gastrointestinal Cancers (MK-9999-02A)No drug interventionstreatment1 / 2recruiting
NCT04401709
Gemcitabine+ Capecitabine Vs Capecitabine in Curatively Resected Biliary Tract CancerNo drug interventionstreatment3recruiting
NCT03144856
Apatinib as Second Line Therapy in Patients With Advanced Refractory Biliary Tract CancersNo drug interventionstreatment2unknown_status
NCT01294085
Case Series Study of Biliary Tract Cancer Patients in JapanNo drug interventionsNot AvailableNot Availablecompleted
NCT03873532
A Trial Evaluating Surufatinib Efficacy and Safety in Biliary Tract Carcinoma PatientsNo drug interventionstreatment2 / 3unknown_status
NCT02346032
Phase II Study of Refametinib, a MEK Inhibitor, as Second-line Treatment in Advanced Biliary Tract AdenocarcinomaNo drug interventionstreatment2completed
NCT03695952
A Prospective Cohort Study of Patients With Hepatobiliary Cancer Treated With Immune Checkpoint InhibitorsNo drug interventionsNot AvailableNot Availableunknown_status
NCT03411200
Patient Activation Through Counseling, Exercise and MobilizationNo drug interventionssupportive_careNot Availablecompleted
NCT05743959
ctDNA Detection of MRD in Predicting Postoperative Recurrence in Biliary Tract Cancers:A Multicenter Prospective TrialNo drug interventionsNot AvailableNot Availablerecruiting
NCT03093870
Varlitinib in Combination With Capecitabine for Advanced or Metastatic Biliary Tract CancerNo drug interventionstreatment2 / 3completed
NCT06139042
Early-stage Detection of LIver, Biliary tRAct and pancReatic CancersNo drug interventionsNot AvailableNot Availablerecruiting
NCT05052099
Phase Ib/II Single-arm Study of mFOLFOX6, Bevacizumab and Atezolizumab in Advanced Biliary Tract CancerNo drug interventionstreatment1 / 2recruiting
NCT01284413
Gemcitabine/Cisplatin/S-1(GCS) Combination Therapy for Patients With Advanced Biliary Tract CancerNo drug interventionstreatment1 / 2completed
NCT06529718
Testing Ivonescimab Versus FOLFOX in Advanced Biliary Tract Cancer PatientsNo drug interventionstreatment2not_yet_recruiting
NCT02829918
Study of Nivolumab in Patients With Advanced Refractory Biliary Tract CancersNo drug interventionstreatment2completed
NCT04727541
Neoadjuvant Bintrafusp Alfa in Patients With Resectable Biliary Tract CancerNo drug interventionstreatment2terminated
NCT01917617
Oral Rehydration Therapy for Short Hydration in Chemotherapy With CDDP Plus GEM for Biliary Tract CancerNo drug interventionstreatment2completed
NCT04318834
Molecular Profiling of Advanced Biliary Tract CancersNo drug interventionsotherNot Availablerecruiting
NCT01572324
Study of Hepatic Arterial Infusion to Treat Biliary Tract CarcinomasNo drug interventionstreatment2completed
NCT03999658
A Study of STI-3031 (an Anti-PD-L1 Antibody) in Patients With Selected Relapsed/Refractory MalignanciesNo drug interventionstreatment2withdrawn
NCT04969835
A Study Evaluating the Safety, Pharmacokinetics and Early Efficacy of AVA6000 in Solid TumoursNo drug interventionstreatment1recruiting
NCT02350686
XELOX in Advanced Biliary Tract Carcinoma After Failure of Gemcitabine-based ChemotherapyNo drug interventionstreatment2unknown_status
NCT00123825
Gemcitabine and Cisplatin for Gallbladder and Biliary Tract Cancertreatment2completed
NCT02908048
Extracellular RNA Markers of Liver Disease and CancerNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT05065957
Study of Combination Therapy of D07001-Softgel Capsules and Xeloda/TS-1 in Subjects With Advanced Biliary Tract CancerNo drug interventionstreatment2 / 3recruiting
NCT02670265
Parenteral Nutrition in Patients With Biliopancreatic Mass LesionsNo drug interventionssupportive_careNot Availablecompleted
NCT04057365
Study of the Combination of DKN-01 and Nivolumab in Previously Treated Patients With Advanced Biliary Tract Cancer (BTC)treatment2terminated
NCT05327582
An Open-label, Phase I/II Study of PLENA Regimen in Patients With Unresectable Pancreatic Cancer or BTCNo drug interventionstreatment1 / 2unknown_status
NCT06202131
Prospective Single-center Study About the Use of ctDNA in the Management of Patients With Tumors of the Gastrointestinal TractNo drug interventionsNot AvailableNot Availablerecruiting
NCT04720131
Camrelizumab Combined With Apatinib and Capecitabine in Patients With Advanced Biliary Tract Cancer.No drug interventionstreatment2completed
NCT03631173
Monitoring of patIents With Microdialysis Following PancreaticoduodenectomyNo drug interventionsdiagnosticNot Availableactive_not_recruiting
NCT03231176
Varlitinib Plus Capecitabine in Chinese Patients With Advanced or Metastatic Biliary Tract CancerNo drug interventionstreatment2completed
NCT01899976
X-MAS Biliary Study With Covered Biliary StentNo drug interventionstreatmentNot Availablecompleted
NCT04203160
Gemcitabine and Cisplatin With or Without CPI-613 as First Line Therapy for Patients With Advanced Unresectable Biliary Tract Cancer (BilT-04)No drug interventionstreatment1 / 2completed
NCT00339560
A Population-Based Case-Control Study of Biliary Tract Cancers in Shanghai, ChinaNo drug interventionsNot AvailableNot Availablecompleted
NCT06255262
Durvalumab Combined With Surufatinib as Maintenance Therapy in Patients With Advanced Biliary Tract CancerNo drug interventionstreatment1 / 2not_yet_recruiting
NCT06037980
CisPlatin plUs Gemcitabine and Nabpaclitaxel (GAP) as pReoperative Chemotherapy Versus Immediate Resection in patIents With resecTable BiliarY Tract Cancers (BTC) at High Risk for RecurrenceNo drug interventionstreatment2 / 3recruiting
NCT00142480
Capecitabine, Oxaliplatin, Bevacizumab and Radiation Therapy in Patients With Biliary Tract and Gallbladder Cancertreatment2completed
NCT03796429
A Study of the Efficacy and Safety of Chemotherapy Combined With Toripalimab in Advanced Biliary Tract CancerNo drug interventionstreatment2completed
NCT06074029
Exploratory Study on the Therapeutic Effect Prediction Model of Advanced BTC ImmunotherapyNo drug interventionsdiagnostic1 / 2active_not_recruiting
NCT06084689
Targeting MDMD and PD1 in Tumors With Tertiary Lymphoid StructuresNo drug interventionstreatment2not_yet_recruiting
NCT03311789
Study of PD-1 Inhibitor in Combination With Gemcitabine/Cisplatin for Advancer BTCsNo drug interventionstreatment1 / 2unknown_status
NCT01308840
Gemcitabine, Oxaliplatin and Panitumumab in Kras/B-raf Wild-Type Biliary Track and Gallbladder CancerNo drug interventionstreatment2completed
NCT02720601
Irinotecan and Capecitabine as Second-line Treatment for Advanced/Metastatic Biliary Tract CancersNo drug interventionstreatment2withdrawn
NCT05994001
Candonilimab in Combination With LM-302 for Claudin 18.2 Positive-advanced Biliary Tract Cancer After Failure of Standard of Chemotherapy and PD1/PD-L1 AntibodyNo drug interventionstreatment1 / 2recruiting
NCT06320301
Adebrelimab and a TKI in Combination With GEMOX in First-line Treatment of Advanced Biliary Tract Cancers (BTC)No drug interventionstreatment2recruiting
NCT05220046
Palliadelic Treatment to Reduce Psychological Distress in Persons With Inoperable Pancreatobiliary CancerNo drug interventionstreatment1recruiting
NCT04571710
A Trial of SHR1258 in Patients With Biliary Tract CancerNo drug interventionstreatment2unknown_status
NCT03937895
Allogeneic NK Cell ("SMT-NK") in Combination With Pembrolizumab in Advanced Biliary Tract CancerNo drug interventionstreatment1 / 2completed
NCT03898895
COmbination of Radiotherapy With Anti-PD-1 Antibody for unREseCtable Biliary Tract CancerNo drug interventionstreatment2recruiting
NCT05487443
The Efficacy of Chemotherapy Combined With Immunocheckpoint Inhibitors in Advanced Biliary MalignanciesNo drug interventionstreatment2 / 3unknown_status
NCT05506943
A Study of CTX-009 in Combination With Paclitaxel in Adult Patients With Unresectable Advanced, Metastatic or Recurrent Biliary Tract Cancers (COMPANION-002)No drug interventionstreatment2 / 3active_not_recruiting
NCT05451043
Durvalumab and Tremelimumab in Combination With Propranolol and Chemotherapy for Treatment of Advanced Hepatopancreabiliary Tumors (BLOCKED)No drug interventionstreatment2recruiting
NCT06431490
A Study of TQB2102 for Injection in the Treatment of HER2-positive Biliary Tract CancerNo drug interventionstreatment1 / 2recruiting
NCT00630890
Cyberknife Radiosurgery Boost for Hilar Cholangiocarcinoma (Klatskin Tumor)No drug interventionstreatment1terminated
NCT04907864
Effect of Multi-modal Intervention Care on Cachexia in Patients With Advanced Cancer Compared to Conventional Management (MIRACLE)No drug interventionssupportive_care2unknown_status
NCT02189421
Multibending vs Conventional Endoscope for Direct Peroral CholangioscopyNo drug interventionsNot AvailableNot Availableunknown_status
NCT03482102
Durvalumab (MEDI4736) and Tremelimumab and Radiation Therapy in Hepatocellular Carcinoma and Biliary Tract CancerNo drug interventionstreatment2recruiting
NCT03110484
Pemetrexed in Combination With Erlotinib as a Salvage Treatment in Patients With Metastatic Biliary Tract Cancer (BTC) Who Failed Gemcitabine Containing Chemotherapy: A Phase II Single Arm Prospective StudyNo drug interventionstreatment2unknown_status
NCT06109779
Rilvegostomig + Chemotherapy as Adjuvant Therapy for Biliary Tract Cancer After Resection (ARTEMIDE-Biliary01)No drug interventionstreatment3recruiting
NCT02586987
A Study to Assess the Safety, Tolerability and Anti-tumour Activity of Ascending Doses of Selumetinib in Combination With MEDI4736 and Selumetinib in Combination With MEDI4736 and Tremelimumab in Patients With Advanced Solid TumoursNo drug interventionstreatment1completed
NCT03044587
Nal-IRI With 5-fluorouracil (5-FU) and Leucovorin or Gemcitabine Plus Cisplatin in Advanced Biliary-tract CancerNo drug interventionstreatment2active_not_recruiting
NCT01234051
Docetaxel and Oxaliplatin Combination With Locally Advanced or Metastatic Biliary Tract CancerNo drug interventionstreatment2unknown_status
NCT04561453
Feasibility Study of Multi-Platform Profiling of Resected Biliary Tract CancerNo drug interventionsNot AvailableNot Availablerecruiting
NCT04935853
Prognostic and Predictive Markers of Response to Treatment in Patients With Bile Duct Cancer: ACABi PRONOBIL StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT03475953
A Phase I/II Study of Regorafenib Plus Avelumab in Solid TumorsNo drug interventionstreatment1 / 2recruiting
NCT05253053
To Evaluate Efficacy and Safety of TT-00420 (Tinengotinib) as Monotherapy and Combination Therapy in Patients With Advanced Solid TumorsNo drug interventionstreatment1 / 2recruiting
NCT02711553
A Study of Ramucirumab (LY3009806) or Merestinib (LY2801653) in Advanced or Metastatic Biliary Tract CancerNo drug interventionstreatment2active_not_recruiting
NCT05512377
Brightline-2: A Study to Test Whether Brigimadlin (BI 907828) Helps People With Cancer in the Biliary Tract, Pancreas, Lung or BladderNo drug interventionstreatment2recruiting
NCT05254847
Capecitabine Combined With Lenvatinib and Tislelizumab as Adjuvant Treatment After Resection in Patients With BTCNo drug interventionstreatment2recruiting
NCT03419247
Molecular Profiling of Advanced Biliary Tract CancersNo drug interventionsdiagnosticNot Availablewithdrawn
NCT06293898
Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid TumorsNo drug interventionstreatment1recruiting
NCT01297998
A Phase I Study of Adjuvant Chemotherapy With GC in Biliary Tract Cancer Undergoing Resection Without Major HepatectomyNo drug interventionstreatment1completed
NCT05429697
Study of SMT-NK Inj. Plus Pembrolizumab vs Pembrolizumab Monotherapy in Patients With Advanced Biliary Tract CancerNo drug interventionstreatment2 / 3recruiting
NCT03718897
Identification of Prognostic Gene Mutations in Biliary Tract Cancer Using Whole Genome SequencingNo drug interventionsNot AvailableNot Availableunknown_status
NCT03801083
Adoptive Transfer of Tumor Infiltrating Lymphocytes for Biliary Tract CancersNo drug interventionstreatment2recruiting
NCT01861483
Vessel Resection and Reconstruction of Biliary Tract CancersNo drug interventionsNot AvailableNot Availablecompleted
NCT01657383
Surgical Outcomes Database For Faculty of Hepatopancreatic Biliary SurgeryNo drug interventionsNot AvailableNot Availablecompleted
NCT05489211
Study of Dato-Dxd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)No drug interventionstreatment2recruiting
NCT03778593
FOLFIRINOX for 2nd-line Treatment of BTCNo drug interventionstreatment2completed
NCT05835778
Imfinzi BTC Japan PMS_Japan Post-Marketing Surveillance (PMS) Study - CEI/SCEINo drug interventionsNot AvailableNot Availablerecruiting
NCT02182778
GEM/Cisplatin/S-1 vs GEM/Cisplatin for Biliary Tract CancerNo drug interventionstreatment3completed
NCT05509478
Lenvatinib Combined With PD-1 Inhibitors as First-line Treatment for Unresectable/Advanced Biliary Tract CarcinomaNo drug interventionstreatment2unknown_status
NCT03486678
SHR-1210 in Combination With GEMOX in Patients With Advanced BTCNo drug interventionstreatment2completed
NCT03185988
Anti-HER2 Therapy in Patients of HER2 Positive Metastatic Carcinoma of Digestive SystemNo drug interventionstreatment2unknown_status
NCT01543607
Endoscopic Therapy of Malignant Bile Duct StricturesNo drug interventionstreatmentNot Availableterminated
NCT04186156
A Study of Selective HDAC6 Inhibition With KA2507 in Advanced Biliary Tract CancerNo drug interventionstreatment2withdrawn
NCT04338685
A Study Evaluating Safety, Pharmacokinetics, Pharmacodynamics, And Clinical Activity Of RO7119929 (TLR7 Agonist) In Participants With Unresectable Advanced Or Metastatic Hepatocellular Carcinoma, Biliary Tract Cancer, Or Solid Tumors With Hepatic MetastasesNo drug interventionstreatment1completed
NCT01291615
Phase I Study of Gemcitabine or S-1 Adjuvant Therapy After Hemihepatectomy for Biliary Tract CancerNo drug interventionstreatment1completed
NCT04776837
Predicting Disease Progression and/or Recurrence in CancerNo drug interventionsNot AvailableNot Availablecompleted
NCT04445532
Hepatobiliary Tumors Tissue Samples AcquisitionNo drug interventionsNot AvailableNot Availablerecruiting
NCT06389500
HAIC+Adebrelimab+Lenvatinib for Conversion Treatment of Potentially Resectable, Locally Advanced Biliary Tract CancerNo drug interventionstreatment2not_yet_recruiting
NCT04163900
Comparing NUC-1031 Plus Cisplatin to Gemcitabine Plus Cisplatin in Patients With Advanced Biliary Tract CancerNo drug interventionstreatment3terminated
NCT05184400
Identification of New Biomarkers for Patients With Cholangiocarcinoma and Gallbladder CancerNo drug interventionsNot AvailableNot Availablerecruiting
NCT02773459
MEK162 in Combination With Capecitabine in Advanced Biliary Tract CancerNo drug interventionstreatment1 / 2completed
NCT04300959
Anlotinib in Combination With PD1 With Gemcitabine Plus(+)Cisplatin for Unresectable or Metastatic Biliary Tract CancerNo drug interventionstreatment2unknown_status
NCT05775159
Study of Novel Immunomodulators as Monotherapy and in Combination With Anticancer Agents in Participants With Advanced Hepatobiliary CancerNo drug interventionstreatment2recruiting
NCT00753675
Vandetanib Gemcitabine Or Placebo Plus Gemcitabine Or Vandetanib Monotherapy In Advanced Biliary Tract Cancertreatment2completed
NCT06282575
Efficacy and Safety of Zanidatamab With Standard-of-care Therapy Against Standard-of-care Therapy for Advanced HER2-positive Biliary Tract CancerNo drug interventionstreatment3recruiting
NCT03291899
Trial of Infusional FOLFIRINOX in First Line Treatment of Advanced Biliary Tract CancersNo drug interventionstreatment2terminated
NCT03830606
The Efficacy and Safety of Nab-paclitaxel Plus S-1 in First-line Treatment of Advanced Biliary Tract AdenocarcinomaNo drug interventionstreatment2completed
NCT02002806
Surgery Plus Celiac Nerve Block for Long-term Pancreatic Cancer Pain ControlNo drug interventionstreatmentNot Availablecompleted
NCT04656249
Lenvatinib in Patients With Previously Treated Advanced Biliary Tract CancerNo drug interventionstreatment2completed
NCT01926236
Active Symptom Control Alone or With mFOLFOX Chemotherapy for Locally Advanced/ Metastatic Biliary Tract CancersNo drug interventionstreatment3completed
NCT04234113
Study of SO-C101 and SO-C101 in Combination With Pembro in Adult Patients With Advanced/Metastatic Solid TumorsNo drug interventionstreatment1active_not_recruiting
NCT03668418
Xenotransplantation of Primary Cancer Samples in Zebrafish EmbryosNo drug interventionsNot AvailableNot Availableunknown_status
NCT06222619
Effect of PVE on Surgical Outcomes and Long-term Survival in Perihilar CholangiocarcinomaNo drug interventionsNot AvailableNot Availablecompleted
NCT04801719
Endoluminal Radiofrequency Ablation for the Treatment of Malignant Biliary StenosisNo drug interventionstreatmentNot Availablecompleted
NCT02443324
A Study of Ramucirumab Plus Pembrolizumab in Participants With Gastric or GEJ Adenocarcinoma, NSCLC, Transitional Cell Carcinoma of the Urothelium, or Biliary Tract CancerNo drug interventionstreatment1completed
NCT05056116
A Safety and Efficacy Study of Surufatinib Combination With Toripalimab in Patients With Recurrent Biliary Tract CancerNo drug interventionstreatmentNot Availableunknown_status
NCT02579616
Study of Lenvatinib (E7080) in Unresectable Biliary Tract Cancer (BTC) Who Failed Gemcitabine-based Combination ChemotherapyNo drug interventionstreatment2completed
NCT04584996
CIRcular and Non-coding RNAs as Clinically USeful Biomarkers in Pancreaticobiliary CancersNo drug interventionsNot AvailableNot Availableunknown_status
NCT05357196
PT-112 (Phosplatin's Platinum) Combine With Gemcitabine Injection for Advanced Solid TumorsNo drug interventionstreatment1 / 2unknown_status
NCT03639935
Rucaparib in Combination With Nivolumab in Patients With Advanced or Metastatic Biliary Tract Cancer Following Platinum TherapyNo drug interventionstreatment2active_not_recruiting
NCT02988635
Early Palliative Care on Quality of Life of Advanced Cancer PatientsNo drug interventionssupportive_care3completed
NCT06465563
Adebrelimab With or Without SHR-8068 in Combination With Cisplatin Plus Gemcitabine as First-line Treatment in Patients With Advanced Biliary Tract CancerNo drug interventionstreatment2recruiting
NCT01494363
Phase II Study of FOLFOXIRI in Patients With Locally Advanced or Metastatic Biliary Tract CancerNo drug interventionstreatment2unknown_status
NCT04608786
A Clinical Study of PD-L1 Antibody ZKAB001 Combined With Capecitabine in Resected Biliary Tract CancerNo drug interventionstreatment1unknown_status
NCT02433639
Study of TH-302 Monotherapy as Second-line Treatment in Advanced Biliary Tract CancerNo drug interventionstreatment2completed
NCT04683939
Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy Trial of BNT141 in Patients With Unresectable or Metastatic CLDN18.2-positive Gastric, Pancreatic, Ovarian and Biliary Tract TumorsNo drug interventionstreatment1 / 2terminated
NCT02489422
Programs To Support You During ChemotherapyNo drug interventionssupportive_careNot Availablecompleted
NCT00090025
XL119 Versus 5-Fluorouracil (5-FU) Plus Leucovorin (LV) in Subjects With Advanced Biliary Tumorstreatment3terminated
NCT05417230
RC48-ADC Combinatioed Envolizumab in Locally Advanced or Metastatic Biliary Tract Cancer With Positive HER-2No drug interventionstreatment2not_yet_recruiting
NCT04637048
Observational Study on Patients With Hepatobiliary TumorsNo drug interventionsNot AvailableNot Availableunknown_status
NCT01821248
A Phase II Trial of Preoperative Chemotherapy for Biliary Tract Cancer (BTC) With Node MetastasisNo drug interventionstreatment2unknown_status
NCT06467357
Phase 3 Study of T-DXd and Rilvegostomig Versus SoC in Advanced HER2-expressing Biliary Tract CancerNo drug interventionstreatment3not_yet_recruiting
NCT03924466
Repeatability of 68-GaNOTA-Anti-HER2 VHH1 PET/CT in Breast Carcinoma PatientsNo drug interventionsdiagnostic2recruiting
NCT02351765
ABC-08: Phase Ib Trial of Acelarin in Combination With Cisplatin in Locally Advanced/ Metastatic Biliary Tract CancersNo drug interventionstreatment1completed
NCT05044065
Blood Flow Restriction Exercise in Patients With Pancreatic, Biliary Tract, and Liver Cancer (PREV-Ex)No drug interventionssupportive_careNot Availablerecruiting
NCT04731220
A Questionnaire Survey for Biliary Tract CancersNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT04784520
A Study of HA121-28 Tablets in Advanced Biliary Tract CancerNo drug interventionstreatment2terminated
NCT03531320
Study of D07001-Softgel Capsules in Subjects With Gastrointestinal Cancer in Dose-Escalation Phase and in Subjects With Biliary Tract Cancer in Dose-Expansion PhaseNo drug interventionstreatment1 / 2completed
NCT04896931
New Prospective Expanded German Registry of Incidental Gallbladder Carcinoma (PERSUASION)- a Permanent Platform Including All Kind of Biliary Tract Cancers (BTC)No drug interventionsNot AvailableNot Availablerecruiting
NCT00361231
Gemcitabine, Oxaliplatin in Combination With Bevacizumab in Biliary Tract and Gallbladder Cancertreatment2completed
NCT03785873
Phase Ib/II Trial of Nal-Irinotecan and Nivolumab as Second-Line Treatment in Patients With Advanced Biliary Tract CancerNo drug interventionstreatment1 / 2active_not_recruiting
NCT04333927
Adjuvant Immunotherapy Combined With Chemoradiation for Patients With High-risk reseCtable Extrahepatic chOlangiocaRcinoma and gallblaDder CancerNo drug interventionstreatment2unknown_status
NCT03079427
Adjuvant Capecitabine vs Gemcitabine Plus Cisplatin in Resected Extrahepatic CholangiocarcinomaNo drug interventionstreatment2completed
NCT06239194
Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid TumorsNo drug interventionstreatment1 / 2recruiting
NCT04066491
Gemcitabine Plus Cisplatin With or Without Bintrafusp Alfa (M7824) in Participants With 1L BTCtreatment2 / 3terminated
NCT06531291
Surufatinib Combined With Serplulimab and Standard Chemotherapy as First-line Treatment in Advanced Solid Tumors With Neuroendocrine DifferentiationNo drug interventionstreatment2not_yet_recruiting
NCT05116891
A Phase 1/2 Study of CAN04 in Combination With Different Chemotherapy Regimens in Subjects With Advanced Solid TumorsNo drug interventionstreatment1 / 2completed
NCT06502080
Consolidative Radiotherapy (CSRT) in Patients With Oligometastatic/Locally Advanced Unresectable Bilary Tract Cancer (BTC)No drug interventionstreatment2not_yet_recruiting
NCT05771480
Durvalumab With Chemotherapy as First Line Treatment in Patients With Advanced Biliary Tract Cancers (aBTCs)No drug interventionstreatment3recruiting
NCT04329429
A Study of RC48-ADC in Subjects With HER2 Overexpressed Metastatic Biliary Tract CancerNo drug interventionstreatment2active_not_recruiting
NCT00832689
Irinotecan, Gemcitabine, Chemotherapy for Biliary Tract Cancertreatment2completed
NCT02992340
Varlitinib in Combination With Gemcitabine and Cisplatin for Treatment naïve Advanced or Metastatic BTCNo drug interventionstreatment1 / 2terminated
NCT00881504
A Study of FOLFOX6 With Bevacizumab for Biliary System Carcinomatreatment2terminated
NCT04677504
A Study of Atezolizumab With or Without Bevacizumab in Combination With Cisplatin Plus Gemcitabine in Patients With Untreated, Advanced Biliary Tract CancerNo drug interventionstreatment2completed
NCT03673072
Neoadjuvant Chemotherapy With Gemcitabine Plus Cisplatin Followed by Radical Liver Resection Versus Immediate Radical Liver Resection Alone With or Without Adjuvant Chemotherapy in Incidentally Detected Gallbladder Carcinoma After Simple Cholecystectomy or in Front of Radical Resection of BTCNo drug interventionstreatment3recruiting
NCT03613168
Trastuzumab in HER2-positive Biliary Tract CancerNo drug interventionstreatment2completed
NCT06546969
Chemoimmunotherapy Combined With Hyperthermia and Spatially-Fractionated Radiotherapy in Advanced Biliary Tract CancerNo drug interventionstreatment1not_yet_recruiting
NCT03260712
Pembrolizumab in Biliary Tract CancerNo drug interventionstreatment2completed
NCT03110510
FOLFIRI as Salvage Treatment in Metastatic Biliary Tract Cancer (BTC) Patients Who Were Failed After Gemcitabine Containing Chemotherapy: A Phase II Single Arm Prospective StudyNo drug interventionstreatment2withdrawn
NCT01171755
Phase II Study of Gemcitabine and TS-1 in Biliary Trat Cancertreatment2terminated
NCT03440450
A Phase 1 Dose-escalation Study of FF-10832 for Treatment of Solid Tumors Including Biliary Tract CancerNo drug interventionstreatment1recruiting
NCT05667350
AssesSment of Early-deteCtion basEd oN liquiD Biopsy in Biliary Tract Cancer (ASCEND-BTC)No drug interventionsNot AvailableNot Availablerecruiting
NCT00414843
Storage of Bile From Routine Procedures to Study Risk FactorsNo drug interventionsNot AvailableNot Availableterminated
NCT03797326
Efficacy and Safety of Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) in Previously Treated Participants With Select Solid Tumors (MK-7902-005/E7080-G000-224/LEAP-005)No drug interventionstreatment2active_not_recruiting
NCT05924880
A Phase 3b, Open-label, Multi-center Study on Durvalumab in Combination With Gemcitabine-based Chemotherapy as 1L Treatment for the Chinese Patients With Unresectable Biliary Tract Cancers (BTC)No drug interventionstreatment3active_not_recruiting
NCT06084481
Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Select Advanced Solid Tumor Indications Receiving Intravenous (IV) ABBV-400No drug interventionstreatment1recruiting
NCT00338988
Oxaliplatin and Capecitabine in Patients With Unresectable Cholangiocarcinomatreatment2completed
NCT04004234
A Phase I/II Study of the Pan-immunotherapy in Patients With Local Advanced/Metastatic BTCNo drug interventionstreatment1 / 2unknown_status
NCT03314935
A Phase 1/2 Study of INCB001158 in Combination With Chemotherapy in Subjects With Solid TumorsNo drug interventionstreatment1 / 2completed
NCT05036486
The Registry of Genetic Alterations of Taiwan Biliary Tract CancerNo drug interventionsNot AvailableNot Availablerecruiting
NCT05239169
Immunotherapy With Durva and Treme With or Without Capecitabine in Adjuvant Treatment for Biliary Tract CancerNo drug interventionstreatment2active_not_recruiting
NCT03790111
A Safety and Efficacy Study of XERMELO® + First-line Chemotherapy in Patients With Advanced Biliary Tract CancerNo drug interventionstreatment2terminated