Metastatic Malignant Neoplasm in the Bone (DBCOND0043810)

Identifiers

Synonyms

Metastases to bone / Bone Metastases / Bony secondaries / Bone cancer metastatic / Bony metastases / Osteolytic bone metastases / Metastasis to bone / Secondary malignant neoplasm of bone (disorder) / Secondary malignant neoplasm of bone and bone marrow

Associated Data

Indicated Drugs and Targets

Not Available

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT04090398	Testing the Addition of Radium Therapy (Radium-223 Dichloride) to the Usual Chemotherapy Treatment (Paclitaxel) for Advanced Breast Cancer That Has Spread to the Bones	Paclitaxel	treatment	2	active_not_recruiting
NCT03858205	Low-Dose Radiotherapy in Treating Painful Bone Metastases in Patients With Multiple Myeloma	No drug interventions	treatment	Not Available	recruiting
NCT04071223	Testing the Addition of a New Anti-cancer Drug, Radium-223 Dichloride, to the Usual Treatment (Cabozantinib) for Advanced Renal Cell Cancer That Has Spread to the Bone, RadiCaL Study	Cabozantinib	treatment	2	recruiting
NCT02699697	Palliative Radiation Therapy in Reducing Pain in Patients With Bone Metastasis	No drug interventions	supportive_care	Not Available	active_not_recruiting
NCT06549478	Biology-Guided Radiation Therapy for the Treatment of Patients with Bone Metastases	No drug interventions	treatment	1	recruiting
NCT02099864	Genetic and Molecular Mechanisms in Assessing Response in Patients With Prostate Cancer Receiving Enzalutamide Therapy	Enzalutamide	treatment	2	active_not_recruiting
NCT02715856	Telemonitoring After Surgery to Preserve Limb Function in Optimizing Mobility in Cancer Survivors With Skeletal Metastases	No drug interventions	health_services_research	Not Available	terminated
NCT00936975	Fluorine F 18 Sodium Fluoride Positron Emission Tomography in Evaluating Response to Dasatinib in Patients With Prostate Cancer and Bone Metastases	No drug interventions	diagnostic	2	completed
NCT03649841	Antiandrogen Therapy, Abiraterone Acetate, and Prednisone With or Without Neutron Radiation Therapy in Treating Patients With Prostate Cancer	Abiraterone Cortisone Prednisone	treatment	2	terminated
NCT05010096	BAY1895344 and Copanlisib for the Treatment of Molecularly Selected Patients With Advanced Solid Tumors	Copanlisib Elimusertib	treatment	1	withdrawn
NCT02499835	Vaccine Therapy and Pembrolizumab in Treating Patients With Hormone-Resistant, Metastatic Prostate Cancer	Pembrolizumab	treatment	1 / 2	completed
NCT03012230	Pembrolizumab and Ruxolitinib Phosphate in Treating Patients With Metastatic Stage IV Triple Negative Breast Cancer	Pembrolizumab Ruxolitinib	treatment	1	completed
NCT02364557	Testing Whether Treating Breast Cancer Metastases With Surgery or High-Dose Radiation Improves Survival	No drug interventions	treatment	2 / 3	active_not_recruiting
NCT03796767	Salvage Oligometastasectomy and Radiation Therapy in Recurrent Prostate Cancer	No drug interventions	treatment	2	active_not_recruiting
NCT01050504	Collecting and Studying Blood and Tissue Samples From Patients With Locally Recurrent or Metastatic Prostate or Bladder/Urothelial Cancer	No drug interventions	Not Available	Not Available	recruiting
NCT02429804	NaF/FDG PET/MRI in Measuring Response to Radium Ra 223 Dichloride in Patients With Metastatic Hormone-Resistant Prostate Cancer	Fludeoxyglucose (18F) Fluoride ion F-18 Fluorine F-18	diagnostic	1	terminated
NCT04693377	Cryoablation Combined With Stereotactic Body Radiation Therapy for the Treatment of Painful Bone Metastases, the CROME Trial	No drug interventions	supportive_care	Not Available	recruiting
NCT04616547	Treatment of Cancer-Related Bone Pain by Using Bone-Targeted Radiation-Based Therapy (Sn-117m-DTPA) in Patients With Prostate Cancer That Has Spread to Bones	No drug interventions	treatment	2	terminated
NCT02306161	Combination Chemotherapy With or Without Ganitumab in Treating Patients With Newly Diagnosed Metastatic Ewing Sarcoma	Beta-D-Glucose Cyclophosphamide Daunorubicin Doxorubicin Etoposide Ganitumab Ifosfamide Sulfate ion Vincristine	treatment	3	active_not_recruiting
NCT03691493	Radiation Therapy, Palbociclib, and Hormone Therapy in Treating Breast Cancer Patients With Bone Metastasis	Anastrozole Exemestane Fulvestrant Letrozole Palbociclib Tamoxifen	treatment	2	completed
NCT04489719	Impact of DNA Repair Pathway Alterations on Sensitivity to Radium-223 in Bone Metastatic Castration-resistant Prostate Cancer	Radium Ra 223 dichloride	Not Available	Not Available	recruiting
NCT04513717	Two Studies for Patients With High Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a High Gene Risk Score, The PREDICT-RT Trial	Apalutamide Bicalutamide Buserelin Degarelix Flutamide Goserelin Histrelin Leuprolide Triptorelin Tryptophan	treatment	3	recruiting
NCT04754425	Erdafitinib for the Treatment of Patients With Castration-Resistant Prostate Cancer	Erdafitinib	treatment	2	active_not_recruiting
NCT05174026	18F-FDG PET-MRI for Planning and Follow-Up of Patients With Spine Tumors Treated With Spine Stereotactic Radiosurgery	No drug interventions	diagnostic	Not Available	completed
NCT03793166	Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer, The PDIGREE Study	Cabozantinib Ipilimumab Nivolumab	treatment	3	active_not_recruiting
NCT04928820	68Ga-PSMA-11 PET/CT for the Diagnosis of Bone Metastases in Patients With Prostate Cancer and Biochemical Progression During Androgen Deprivation Therapy	No drug interventions	diagnostic	2	terminated
NCT03749460	Nivolumab and Ipilimumab and Stereotactic Body Radiation Therapy in Treating Patients With Salivary Gland Cancers	Ipilimumab Nivolumab	treatment	1 / 2	completed
NCT02565901	Sirolimus, Docetaxel, and Carboplatin in Treating Patients With Metastatic Castration-Resistant Prostate Cancer	Carboplatin Docetaxel Sirolimus	treatment	1 / 2	terminated
NCT05924672	Efficacy of Ra-223 in PSMA PET Optimally Selected Patients	Medronic acid Radium Ra 223 dichloride Radium Ra-223 Technetium Tc-99m Technetium Tc-99m medronate	treatment	2	not_yet_recruiting
NCT03204812	Durvalumab and Tremelimumab in Treating Chemotherapy Naive Patients With Metastatic Castration-Resistant Prostate Cancer	Durvalumab Tremelimumab	treatment	2	completed
NCT01833208	Radiation Therapy in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer Receiving Sipuleucel-T	No drug interventions	treatment	Not Available	completed