Cutaneous Squamous Cell Carcinoma (CSCC) (DBCOND0168836)

Identifiers

Synonyms
Squamous Cell Carcinoma Skin / Carcinoma, Squamous Cell, Skin / Carcinoma, Cutaneous Squamous Cell / Cutaneous Squamous Cell Carcinoma / Squamous Cell Carcinoma of Skin / Skin Squamous Cell Carcinoma / Epidermoid Carcinoma / Squamous Cell Skin Carcinoma / Squamous Cell Carcinoma, Skin / Squamous Cell Carcinoma of the Skin / Squamous cell carcinoma of skin (disorder) / Planocellular carcinoma / Squamous cell carcinoma (morphologic abnormality) / Squamous cell carcinoma (disorder) / Carcinoma, Squamous Cell / Squamous cell carcinoma / Carcinoma epidermoid / Carcinoma squamous

Associated Data

Indicated Drugs and Targets
Not Available
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT06608511
Liquid Biomarker Study in Melanoma and Non-Melanoma Skin CancersNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT06585410
Study of Intralesional Cemiplimab in Adult Patients With Early Stage Cutaneous Squamous Cell Carcinomatreatment3not_yet_recruiting
NCT05620134
Study of JK08 in Patients with Unresectable Locally Advanced or Metastatic Cancertreatment1 / 2recruiting
NCT06384053
Skin Cancer and Hyperthermia and RadiotherapyNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT05845632
Time to Treatment and Disease-free Survival of Patients With High-risk Head-neck Cutaneous Squamous Cell CarcinomaNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT04362722
Intratumoral Administration of Daromun in Non-melanoma Skin Cancer Patientstreatment2recruiting
NCT04616248
In Situ Immunomodulation With CDX-301, Radiation Therapy, CDX-1140 and Poly-ICLC in Patients w/ Unresectable and Metastatic Solid Tumorstreatment1recruiting
NCT06036836
Study of Favezelimab Coformulated With Pembrolizumab (MK-4280A) in Participants With Selected Solid Tumors (MK-4280A-010)treatment2recruiting
NCT05108090
Sentinel Lymph Node Biopsy for Cutaneous Squamous Cell Carcinoma of the Head and NeckNo drug interventionsscreeningNot Availablerecruiting
NCT04329221
Immunotherapy Before Transplantation for Skin Cancer Prevention in Organ Transplant Recipientsprevention2not_yet_recruiting
NCT04853602
IFx-Hu2.0 Expanded Access ProgramNot AvailableNot Availableavailable
NCT04916002
A Trial To Find Out If Vidutolimod Together With Cemiplimab Is Safe And If It Works In Adult Participants With Advanced Cancer Or Metastatic Cancertreatment2active_not_recruiting
NCT04642287
Immunotherapy After Transplantation for Skin Cancer Prevention in Organ Transplant Recipientstreatment2not_yet_recruiting
NCT04632433
Neoadjuvant Plus Adjuvant Treatment With Cemiplimab in Cutaneaous Squamous Cell Carcinomatreatment2active_not_recruiting
NCT02672254
New Strategies Against Cutaneous Squamous Cell CarcinomaNo drug interventionsNot AvailableNot Availablecompleted
NCT06008977
Exercise to Boost Response to Checkpoint Blockade ImmunotherapyNo drug interventionsotherNot Availablerecruiting
NCT04710498
Neoadjuvant Atezolizumab in Surgically Resectable Advanced Cutaneous Squamous Cell Carcinomatreatment2active_not_recruiting
NCT03836105
CemiplimAb Survivorship EpidemiologyNot AvailableNot Availableactive_not_recruiting
NCT06014697
OCT and Invasion in Cutaneous Skin LesionsNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT04502888
Ph1 Study of SL-172154 Administered Intratumorally in Subjects With Squamous Cell Carcinoma of the Head and Neck or SkinNo drug interventionstreatment1terminated
NCT05878288
Deep sequencIng in Cutaneous Squamous CEll caRciNomasother2active_not_recruiting
NCT04975152
Neoadjuvant Cemiplimab in Newly Diagnosed or Recurrent Stage I-II Merkel Cell Carcinoma and Locoregionally Advanced Cutaneous Squamous Cell Carcinomatreatment1recruiting
NCT04620200
Neo-adjuvant Nivolumab or Nivolumab With Ipilimumab in Advanced Cutaneous Squamous Cell Carcinoma Prior to Surgerytreatment2recruiting
NCT05724875
FLASH Radiotherapy for Skin CancerNo drug interventionstreatmentNot Availablerecruiting
NCT04050436
Study Evaluating Cemiplimab Alone and Combined With RP1 in Treating Advanced Squamous Skin Cancertreatment2active_not_recruiting
NCT06014619
Complications and Recurrences After Mohs Micrographic Surgery and Slow MohsNo drug interventionsNot AvailableNot Availablerecruiting
NCT05729139
Cemiplimab/Peg-Interferon-α in Advanced CSCCtreatment1withdrawn
NCT05695222
Cutaneous Squamous Cell Carcinoma Staging StudyNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT03775525
Study Evaluating GZ17-6.02 in Patients With Advanced Solid Tumors or in Combination With Capecitabine in Metastatic Hormone Receptor Positive Breast Cancertreatment1active_not_recruiting
NCT06046625
Needs and Preferences of Patients With Head-neck Cutaneous SCCNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT06536257
Personalised Immunotherapy PlatformNo drug interventionsNot AvailableNot Availablerecruiting
NCT06090266
A Study of OR502, a Monoclonal Antibody Targeting LILRB2, Alone and in Combination With Anticancer Agentstreatment1 / 2recruiting
NCT04160065
Immunotherapy With IFx-Hu2.0 Vaccine for Advanced Non-melanoma Skin Cancerstreatment1active_not_recruiting
NCT06384820
Study of Cemiplimab Alone or in Combination With Fianlimab and/or Other Experimental Agents in Adult Participants With Peri-operative Stage III/IV Cutaneous Squamous Cell Carcinoma (CSCC)treatment2withdrawn
NCT04664582
Sentinel Lymph Node Biopsy for Cutaneous Squamous Cell Carcinoma of the Head and NeckNo drug interventionstreatmentNot Availableunknown_status
NCT03901573
High-Risk Skin Cancers With Atezolizumab Plus NT-I7treatment1 / 2terminated
NCT05076760
MEM-288 Oncolytic Virus Alone and in Combination With Nivolumab in Solid Tumors Including Non-Small Cell Lung Cancertreatment1recruiting
NCT05086692
A Beta-only IL-2 ImmunoTherapY Studytreatment1 / 2recruiting
NCT05888844
A Study to Evaluate INCB099280 in Participants With Advanced Cutaneous Squamous Cell CarcinomaNo drug interventionstreatment2active_not_recruiting
NCT06536946
B-catenin in Cutaneous Squamous Cell Carcinoma and Its MimickersNo drug interventionsNot AvailableNot Availablerecruiting
NCT03889912
Intralesional Cemiplimab for Adult Patients With Cutaneous Squamous Cell Carcinoma or Basal Cell Carcinomatreatment1recruiting
NCT04389112
Study of Metabolic Changes in the Transformation Malignant Precancerous Skin LesionsNo drug interventionsdiagnosticNot Availablerecruiting
NCT06020612
Interobserver Variability DesmoplasiaNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT05256381
A Study of SOT101 in Combination With Pembrolizumab to Evaluate the Efficacy and Safety in Patients With Selected Advanced Solid Tumorstreatment2active_not_recruiting
NCT06567314
Phase 2 Study of Ivonescimab in Patients With Cutaneous Squamous Cell Carcinomatreatment2not_yet_recruiting
NCT02076243
Treatment With Nab-paclitaxel in Cutaneous SCCtreatment2terminated
NCT04596033
TiTAN-1: Safety, Proliferation and Persistence of GEN-011 Autologous Cell Therapytreatment1terminated
NCT01500954
Microarray Analysis of microRNA Expression Profiles in Cutaneous Squamous Cell CarcinomaNo drug interventionsNot AvailableNot Availablecompleted
NCT05377905
Microneedle Array Plus Doxorubicin in Cutaneous Squamous Cell Cancer (cSCC)treatment1 / 2recruiting
NCT06342297
Dermatoscopy Guided Resection for Skin CancerNo drug interventionstreatmentNot Availablerecruiting
NCT06577311
Evaluating the Use of Photodynamic Therapy to Treat Facial Cutaneous Squamous Cell Carcinoma in Situ (SCCis)treatment2recruiting
NCT04301011
Study of TBio-6517 Given Alone or in Combination With Pembrolizumab in Solid Tumorstreatment1 / 2terminated
NCT04429542
Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid TumorsNo drug interventionstreatment1recruiting
NCT04242199
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099280 in Participants With Advanced Solid TumorsNo drug interventionstreatment1active_not_recruiting
NCT04349436
A Phase 1B/2 Study of RP1 in Solid Organ Transplant Patients With Advanced Cutaneous MalignanciesNo drug interventionstreatment1 / 2recruiting
NCT04925713
IFx-Hu2.0 for the Treatment of Patients With Skin Cancertreatment1completed
NCT05565417
Study of the Monoclonal Antibody IMT-009 in Patients With Advanced Solid Tumors or Lymphomastreatment1 / 2recruiting
NCT03082534
Pembrolizumab Combined With Cetuximab for Treatment of Recurrent/Metastatic Head & Neck Squamous Cell Carcinomatreatment2active_not_recruiting
NCT04272034
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Advanced Solid TumorsNo drug interventionstreatment1active_not_recruiting
NCT04616196
Study of NKTR 255 in Combination With Cetuximab in Solid Tumorstreatment1 / 2completed
NCT05238363
The Efficacy and Safety of HLX07 in Locally Advanced or Metastatic Cutaneous Squamous Cell Carcinoma (CSCC)No drug interventionstreatment2unknown_status
NCT04985825
Imgatuzumab in Patients With Advanced Cutaneous Squamous Cell Carcinomatreatment2withdrawn
NCT05220748
RM-1995 Photoimmunotherapy, as Monotherapy or Combined With Pembrolizumab, in Patients With Advanced CuSCC and HNSCCtreatment1withdrawn
NCT05493826
Real World Study on the Use of Cemiplimab in Adult Patients in UKNo drug interventionsNot AvailableNot Availablecompleted
NCT03524326
Testing Lenvatinib and Cetuximab in Patients With Advanced Head and Neck Squamous Cell Carcinoma and Cutaneous Squamous Cell Carcinomatreatment1completed
NCT05859074
A Study of MQ710 With and Without Pembrolizumab in People With Solid Tumor Cancertreatment1active_not_recruiting
NCT05741073
Outcome Research of a European Registry Platform on Real-world Treatment Data of Patients With Advanced NMSCNo drug interventionsNot AvailableNot Availablerecruiting
NCT04242173
Cemiplimab-rwlc for Unresectable Locally Recurrent and/or Metastatic CSCCtreatment2terminated
NCT05286294
Microbiota Transplant to Cancer Patients Who Have Failed Immunotherapy Using Faeces From Clinical Responderstreatment2recruiting
NCT06288191
Neoadjuvant Nivolumab and Relatlimab in Cutaneous Squamous Cell Carcinomatreatment2not_yet_recruiting
NCT04339062
Cemiplimab in AlloSCT/SOT Recipients With CSCCtreatment1 / 2active_not_recruiting
NCT05482880
Decisional Conflicts, Health-related QoL and Satisfaction With Care in High-risk cSCC in the Head-neck RegionNo drug interventionsNot AvailableNot Availablerecruiting
NCT03492489
Expanded Access Protocol for Cemiplimab in Metastatic or Locally Advanced Cutaneous Squamous Cell CarcinomaNot AvailableNot Availableno_longer_available
NCT05574101
A Study of Radiation Therapy and Cemiplimab for People With Skin Cancertreatment2recruiting
NCT03212404
Phase 1 Study of CK-301 (Cosibelimab) as a Single Agent in Subjects With Advanced Cancerstreatment1recruiting
NCT03969004
Study of Adjuvant Cemiplimab Versus Placebo After Surgery and Radiation Therapy in Patients With High Risk Cutaneous Squamous Cell Carcinomatreatment3recruiting
NCT04252612
Biological Outcomes of Pramlintide in Resectable Cutaneous Squamous Cell Carcinoma: A Pilot Studytreatment0withdrawn
NCT03982212
A Window of Opportunity Trial of Intratumoral Injection of Copaxone® in Patients With Percutaneously Accessible Tumorstreatment1active_not_recruiting
NCT05358938
Exercise to Boost Response to Checkpoint Blockade Immunotherapytreatment0active_not_recruiting
NCT04154943
Study of Cemiplimab in Patients With Type of Skin Cancer Stage II to IV Cutaneous Squamous Cell Carcinomatreatment2active_not_recruiting
NCT02218164
Capecitabine or 5-FU With Pegylated Interferon Alpha-2b in Unresectable/Metastatic Cutaneous Squamous Cell Carcinomatreatment2completed
NCT04913220
A Study of SAR444245 Combined With Cemiplimab for the Treatment of Participants With Various Advanced Skin Cancers (Pegathor Skin 201)treatment1 / 2active_not_recruiting
NCT02321982
Same-day Versus Separate-day Preoperative Consultation for Mohs SurgeryNo drug interventionshealth_services_researchNot Availablewithdrawn
NCT06610071
NIFR Image-guided Surgery for Malignant Soft Tissue Tumor With Low-dose SWIG TechniqueNo drug interventionstreatment1not_yet_recruiting
NCT03353077
Alpha Radiation Emitters Device for the Treatment of Squamous Cell Carcinoma (DaRT)No drug interventionstreatmentNot Availablecompleted
NCT03822988
ACCEPTABILITY AND WRITING FREQUENCY OF ADVANCED DIRECTIVES IN ONCO-DERMATOLOGY PATIENTSNo drug interventionsNot AvailableNot Availableunknown_status
NCT02964559
Pembrolizumab in Patients With Locally Advanced or Metastatic Skin Cancertreatment2completed
NCT00954226
Phase Ib Study of Erlotinib Prior to Surgery in Patients With Head and Neck Cancertreatment1active_not_recruiting
NCT05269381
Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumorstreatment1 / 2recruiting
NCT06223659
EMLA Topical Cream for Treatment of Pain in Patients Receiving Intra-Dermal Technetium 99 Injections for Lymphoscintigraphy for Skin Cancerstreatment2recruiting
NCT04234113
Study of SO-C101 and SO-C101 in Combination With Pembro in Adult Patients With Advanced/Metastatic Solid Tumorstreatment1active_not_recruiting
NCT03944941
Avelumab With or Without Cetuximab in Treating Patients With Advanced Skin Squamous Cell Cancertreatment2active_not_recruiting
NCT02978625
Talimogene Laherparepvec and Nivolumab in Treating Patients With Refractory Lymphomas or Advanced or Refractory Non-melanoma Skin Cancerstreatment2active_not_recruiting
NCT03108131
Cobimetinib and Atezolizumab in Treating Participants With Advanced or Refractory Rare Tumorstreatment2completed
NCT01807546
Oral Rigosertib for Squamous Cell Carcinomatreatment2completed
NCT03546998
Epidermoid Cancer Development in Esophageal AchalasiaNo drug interventionsNot AvailableNot Availablerecruiting
NCT01581840
Radiochemotherapy With Panitumumab in the Localised Epidermoid Carcinoma of the Anustreatment1 / 2completed
NCT04583605
The Aim of This Study is to Demonstrat That Vacuum-assisted Closure Versus Conventional Wound Closure Enables to Diminish Local Complications After Lymph Node Dissection in Patients With Metastatic Skin TumorsNo drug interventionsNot AvailableNot Availableunknown_status
NCT03773744
MG1-MAGEA3 With Ad-MAGEA3 and Pembrolizumab in Patients With Previously Treated Metastatic Melanoma or Cutaneous Squamous Cell Carcinomatreatment1withdrawn
NCT01764607
Sirolimus in Kidney Transplant Patients With Squamous Cell Skin Carcinomatreatment2terminated
NCT02997553
Fluorescence for Sentinel Lymph Node Identification in Cancer Surgerydiagnostic3completed
NCT01017185
Study of HF10 in Patients With Refractory Head and Neck Cancer or Solid Tumors With Cutaneous and/or Superficial LesionsNo drug interventionstreatment1completed
NCT00563290
Dasatinib in Treating Patients With Unresectable or Metastatic Squamous Cell Skin Cancer or RAI Stage 0-I Chronic Lymphocytic Leukemiatreatment2completed
NCT01823679
Capecitabine in Treating Patients With Advanced or Recurrent Squamous Cell Carcinoma of the Skintreatment2terminated
NCT04480645
CivaDerm(TM) Surface Therapy Pilot StudyNo drug interventionstreatment0unknown_status
NCT03370861
How Microbes and Metabolism May Predict Skin Cancer Immunotherapy OutcomesNo drug interventionsNot AvailableNot Availableterminated
NCT05246228
Immune System Modulation and Outcome in High-risk cSCC Treated With Surgery and RadiotherapyNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT06327971
Enhanced Outcome Prediction in Cutaneous Squamous Cell Carcinoma Using Deep-learning and Computational HistopathologyNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT01465815
Phase I/II Study of Postoperative Adjuvant Chemoradiation for Advanced-Stage Cutaneous Squamous Cell Carcinoma of the Head and Neck (cSCCHN)treatment1 / 2withdrawn
NCT04204837
Nivolumab for Treatment of Squamous Cell Carcinoma of the Skintreatment2recruiting
NCT02347813
Preventing Squamous Cell Skin Cancerprevention2completed
NCT06014086
Intratumoral PH-762 for Cutaneous CarcinomaNo drug interventionstreatment1recruiting
NCT00089180
T4N5 Liposomal Lotion in Preventing The Recurrence of Nonmelanoma Skin Cancer in Patients Who Have Undergone a Kidney Transplantprevention2completed
NCT03737721
The UNSCARRed Study: UNresctable Squamous Cell Carcinoma Treated With Avelumab and Radical Radiotherapytreatment2active_not_recruiting
NCT03291002
Study of Intratumoral CV8102 in cMEL, cSCC, hnSCC, and ACCtreatment1unknown_status
NCT05490485
Camrelizumab Combined With Cisplatin in the Treatment of Advanced Cutaneous Squamous Cell Carcinomatreatment2recruiting
NCT04892849
Clinical Benefit and Biomarker Analysis of Combination of PD-1/PD-L1 Immune Checkpoint Inhibitors and RadiotherapyNo drug interventionsNot AvailableNot Availablerecruiting
NCT02717936
Investigation of Desmoplastic Squamous Cell CarcinomaNo drug interventionsdiagnosticNot Availableunknown_status
NCT03894618
SL-279252 (PD1-Fc-OX40L) in Subjects With Advanced Solid Tumors or LymphomasNo drug interventionstreatment1completed
NCT02507076
Isolated Limb Perfusion With Melphalan in Treating Patients With Stage IIIB-IV Melanoma or SarcomatreatmentNot Availablewithdrawn
NCT03621462
Elucid Labs AIDA™ - Labelled Image Acquisition ProtocolNo drug interventionsdiagnosticNot Availableunknown_status
NCT01984892
Treatment of Solid Tumors With Intratumoral Hiltonol® (Poly-ICLC)treatment2terminated
NCT05886140
Carrilizumab Combined With White Purple for Squamous Cell Carcinoma of SkintreatmentNot Availablerecruiting
NCT00126555
Gefitinib in Treating Patients Who Are Undergoing Surgery and/or Radiation Therapy for Locally Advanced or Recurrent Squamous Cell Skin Cancertreatment2completed
NCT02324608
Cetuximab Before Surgery in Treating Patients With Aggressive Locally Advanced Skin CancertreatmentNot Availablecompleted