Gram Positive Bacterial Infections (DBCOND0070817)

Identifiers

Synonyms
Gram Positive Bacterial Infection / Infections, Gram-Positive Bacterial / Gram-positive Bacterial Infection / Gram-Positive Bacterial Infections / Bacterial infection, unspecified / Bacterial infectious disease (disorder) / Bacterial infection / Bacterial Infections / Bacterial infection of unspecified site / Bacterial infectious disorders / Bacterial infection NOS / Infection bacterial

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Cefpirome
An antibiotic indicated in the treatment of a wide variety of infections in the body.
No drug targets
Dalbavancin
An antibacterial used to treat acute bacterial skin and skin structure infections (ABSSSI) caused by susceptible strains of Gram-positive bacteria.
Oritavancin
An antibacterial agent used to treat acute bacterial skin and skin structure infections caused by susceptible Gram-positive bacteria.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT01019395
Pharmacokinetics (PK) and Safety Evaluation of Daptomycin in Children Ages 3-24 Months With Proven or Suspected Gram-positive Infections or Peri-Operative Subjects Receiving Prophylactic Antibioticsbasic_science1completed
NCT02134301
Open-Label, Dose-Finding, Pharmacokinetics, Safety and Tolerability Study of Oritavancin in Pediatric Patients With Suspected or Confirmed Bacterial Infectionstreatment1recruiting
NCT00061633
Phase 2 Trial of TD 6424 (Telavancin) Versus Standard Therapy for Complicated Gram Positive Skin and Skin Structure Infections (Gram Positive cSSSI)treatment2completed
NCT00077675
Phase 2 Trial of TD-6424 (Telavancin) Versus Standard Therapy for Complicated Gram Positive Skin and Skin Structure Infections (Gram Positive cSSSI)treatment2completed
NCT01446289
Immune Response Induced by a Vaccine Against Group B Streptococcus and Safety in Pregnant Women and Their OffspringsNo drug interventionsprevention2completed
NCT06592586
A Follow-up Trial of GBS-NN/NN2 Vaccine in Healthy Pregnant WomenNo drug interventionsprevention2 / 3not_yet_recruiting
NCT03159403
A Retrospective Observational Study to Evaluate the Utilization, Outcomes, and Adverse Events in Participants Treated With Orbactiv® (Oritavancin) for Infections Caused by Gram Positive Bacteria in a Real World SettingNot AvailableNot Availablecompleted
NCT04847921
Substance Use Disorder (SUD)-Associated Infections' Treatment With Dalbavancin ENabling OUtpatient Transitiontreatment2 / 3terminated
NCT00736554
What is the Prevalence of Methicillin-Resistant Staphylococcus Aureus in Skin and Soft Tissue Infections Presenting to the Emergency Departments of a Canadian Academic Health Care Center?No drug interventionsNot AvailableNot Availablecompleted
NCT00055198
Daptomycin for the Treatment of Infections Due to Gram-Positive Bacteriatreatment3terminated
NCT03747497
Contezolid Acefosamil Versus Linezolid for the Treatment of Acute Bacterial Skin and Skin Structure Infectiontreatment2completed
NCT02750761
A Study of Oral and Intravenous (IV) Tedizolid Phosphate in Hospitalized Participants, Ages 2 to <12 Years, With Confirmed or Suspected Bacterial Infection (MK-1986-013)treatment1completed
NCT00147511
Time To Efficacy and Onset Of Action Of Linezolidtreatment4completed
NCT00167999
Study Evaluating Piperacillin-Tazobactam on Certain Bacteria in Hematology and Oncology UnitsNot AvailableNot Availablecompleted
NCT02013141
Telavancin Pediatric PK Study (Ages >12 Months to 17 Years)basic_science1terminated
NCT03361163
Controlled Human Infection for Vaccination Against Streptococcus PyogenesNo drug interventionsbasic_science1completed
NCT00167960
Study Evaluating Vancomycin-Resistant Enterococci in a Hematology UnitNot AvailableNot Availablecompleted
NCT00081744
Study Comparing Tigecycline to Imipenem/Cilastatin in Complicated Intra-Abdominal Infections in Hospitalized Subjectstreatment3completed
NCT03560440
Evaluation of the Dosing Regimen of Vancomycin in Pediatric PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT00035269
New Antibiotic to Treat Patients With Community-acquired Pneumonia Due to a Specific Bacteria (S. Pneumoniae Pneumonia)No drug interventionstreatment3completed
NCT03438214
Effect of Intermittent Infusion Versus Continuous Infusion of Vancomycin on Kidney Failure in Critically Ill Patientstreatment4unknown_status
NCT00501150
Oral Antibiotic Treatment at Home Instead of Intravenous Treatment in Hospital for Resistant Gram Positive InfectionstreatmentNot Availablecompleted
NCT06444802
Model-informed Precision Dosing for Linezolidtreatment3not_yet_recruiting
NCT00108433
Linezolid in the Treatment of Hemodialysis Patients With Catheter-Related Gram-Positive Bloodstream Infectionstreatment3terminated
NCT00062647
Telavancin for Treatment of Uncomplicated Staphylococcus Aureus Bacteremiatreatment2completed
NCT00240747
Open-label, Multiple-dose, Phase III Study of the Population Pharmacokinetics of I.V. Synercid in 75 Pediatric Patientstreatment3terminated
NCT00406198
Impact of Continuous Venovenous Haemofiltration on Organ Failure During the Early Phase of Severe SepsisNo drug interventionssupportive_care4completed
NCT00835783
Validation Study of Combined Positron Emission Tomography/Computer Tomography to Diagnose Infection and InflammationNo drug interventionsNot AvailableNot Availableterminated
NCT03964493
TNP-2092 to Treat Acute Bacterial Skin and Skin Structure Infectiontreatment2completed
NCT05824988
Drug Exposure and Minimum Inhibitory Concentration in the Treatment of MAC Lung DiseaseNo drug interventionsNot AvailableNot Availablerecruiting
NCT03896685
Evaluating Newly Approved Drugs in Combination Regimens for Multidrug-Resistant TB With Fluoroquinolone Resistance (endTB-Q)treatment3active_not_recruiting
NCT01212432
Daptomycin Pharmacokinetics in Critically Ill Patients Undergoing Continuous Veno-venous Hemodiafiltration, a Dose Finding Studytreatment2unknown_status
NCT04911270
Clinical Decision Support Tool for Vancomycin Dosing in ChildrenNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT01564758
Post Marketing Surveillance Study on LinezolidNot AvailableNot Availablecompleted
NCT03982030
Dalbavancin Outpatient Pilottreatment4withdrawn
NCT00529282
A Study of Ceftobiprole in Patients With Fever and Neutropenia.treatment3terminated
NCT00079976
Study Evaluating Tigecycline in Selected Serious Infections Caused by Vancomycin-Resistant Enterococcus (VRE) or Methicillin-Resistant Staphylococcus Aureus (MRSA)treatment3completed
NCT04917380
The Clinical Character,Risk and Prognosis of Post-neurosurgical Intracranial Infection With Different Pathogens.No drug interventionsNot AvailableNot Availableunknown_status
NCT00136292
Study of Single Dose Daptomycin in Pediatric Patients With Gram-positive Infection for Which They Are Receiving Standard AntibioticsNot Available1completed
NCT00874367
Early-Onset Sepsis Surveillance StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT01412801
Magnitude of the Antibody Response to and Safety of a GBS Trivalent Vaccine in HIV Positive and HIV Negative Pregnant Women and Their OffspringsNo drug interventionsprevention2completed
NCT00037050
Antibiotic Treatment for Infections of Short Term In-dwelling Vascular Catheters Due to Gram Positive Bacteriatreatment3completed