advanced transitional cell carcinoma (DBCOND0103413)

Identifiers

Synonyms
Advanced Urothelial Carcinoma

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Vinflunine
A vinca alkaloid used to treat advanced or metastatic transitional cell carcinoma of the urothelial tract after a platinum containing treatment has failed.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT06639347
A Trial of SHR-A2102 With Antitumor Therapy in Advanced Urothelial CarcinomaNo drug interventionstreatment1 / 2not_yet_recruiting
NCT04514484
Testing the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIVtreatment1active_not_recruiting
NCT05544552
Safety and Preliminary Anti-Tumor Activity of TYRA-300 in Advanced Urothelial Carcinoma and Other Solid Tumors With FGFR3 Gene AlterationsNo drug interventionstreatment1 / 2recruiting
NCT06079112
9MW2821 Combined With Toripalimab Injection in Subjects With Local Advanced or Metastatic Urothelial Cancertreatment1 / 2recruiting
NCT06196736
A Study to Evaluate 9MW2821 Versus Chemotherapy in Subjects With Previously Treated Locally Advanced or Metastatic Urothelial CancerNo drug interventionstreatment3recruiting
NCT06598761
Postoperative Adjuvant Immunotherapy Combined with Radiotherapy Versus Surgery Alone in Locally Advanced UTUCNo drug interventionsNot AvailableNot Availablerecruiting
NCT02735252
PROMOTE: Identifying Predictive Markers of Response for Genitourinary CancerNo drug interventionsbasic_scienceNot Availableactive_not_recruiting
NCT04871334
Safety, Tolerability and Pharmacokinetics of TWP-101 in Patients With Advanced Melanoma and Urothelial CarcinomaNo drug interventionstreatment1unknown_status
NCT02599324
Study to Evaluate Ibrutinib Combination Therapy in Patients With Selected Gastrointestinal and Genitourinary Tumorstreatment1 / 2completed
NCT00365157
Eribulin Mesylate in Treating Patients With Locally Advanced or Metastatic Cancer of the Urothelium and Kidney Dysfunctiontreatment1 / 2active_not_recruiting
NCT04064190
Vactosertib With Durvalumab in Urothelial Carcinoma Failing Checkpoint Inhibitiontreatment2not_yet_recruiting
NCT05687721
Copanlisib and Avelumab as a Maintenance Therapy for Advanced Bladder Cancertreatment1 / 2not_yet_recruiting
NCT05738161
Magrolimab in Combination With Cytotoxic Chemotherapy in Advanced Urothelial Carcinomatreatment1withdrawn
NCT01487915
Gemcitabine-Carboplatin Versus Gemcitabine-Oxaliplatin in Cisplatin-unfit Urothelial CarcinomaNo drug interventionstreatment2unknown_status
NCT05733000
CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid Tumorstreatment2recruiting
NCT04491942
Testing the Addition of an Anti-cancer Drug, BAY 1895344, to the Usual Chemotherapy Treatment (Cisplatin, or Cisplatin and Gemcitabine) for Advanced Solid Tumors With Emphasis on Urothelial Cancertreatment1active_not_recruiting
NCT05929235
A Study of FX-909 in Patients With Advanced Solid Malignancies, Including Advanced Urothelial CarcinomaNo drug interventionstreatment1recruiting
NCT00942331
Gemcitabine Hydrochloride and Cisplatin With or Without Bevacizumab in Treating Patients With Advanced Urinary Tract Cancertreatment3completed
NCT05318573
A Study to Evaluate Safety, Efficacy of FF-10832 in Combo With Pembrolizumab in Urothelial & Non-small Cell Lung Cancertreatment2recruiting
NCT04856189
Selinexor and Pembrolizumab for the Treatment of Cisplatin-Ineligible or Cisplatin-Refractory Locally Advanced or Metastatic Urothelial Carcinomatreatment1 / 2recruiting
NCT04603846
A Study of Anti-PD-L1 Antibody ZKAB001 Combined With Albumin-bound Paclitaxel in Advanced Urothelial Carcinomatreatment1unknown_status