Primary Prevention of Cardiovascular Diseases (DBCOND0105014)

Identifiers

Synonyms

Cardiovascular Primary Prevention Strategy / Primary Cardiovascular Prevention / Cardiovascular Primary Prevention / Primary Prevention of Cardiovascular Disease / Primary prevention of cardiovascular disease (regime/therapy)

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Rosuvastatin	An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.	3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget Cytochrome P450 2C9enzyme ATP-binding cassette sub-family C member 4transporter Solute carrier organic anion transporter family member 1A2transporter Solute carrier organic anion transporter family member 1B3transporter Solute carrier organic anion transporter family member 2B1transporter Cystine/glutamate transportertransporter Solute carrier organic anion transporter family member 1B1transporter Bile salt export pumptransporter Broad substrate specificity ATP-binding cassette transporter ABCG2transporter Albumincarrier ATP-binding cassette sub-family C member 2transporter Organic anion transporter 3transporter Hepatic sodium/bile acid cotransportertransporter Integrin alpha-Ltarget

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT05431309	Role of Screening With Coronary Computed Tomography Angiography in Primary Prevention of Coronary Heart Disease	No drug interventions	prevention	Not Available	not_yet_recruiting
NCT03439267	Effectiveness of a Proactive Cardiovascular Primary Prevention Strategy, With or Without the Use of Coronary Calcium Screening, in Preventing Future Major Adverse Cardiac Events	Calcium	prevention	Not Available	recruiting
NCT01889030	Cardiovascular Risk Stratification of Ambulatory Patients in Primary Prevention	No drug interventions	Not Available	Not Available	completed
NCT06408493	Peer-led Digital Health Lifestyle Intervention for a Low Income Community at Risk for Cardiovascular Diseases (MYCardio-PEER)	No drug interventions	prevention	Not Available	recruiting
NCT03387384	Appropriateness of Aspirin Use in Medical Outpatients	No drug interventions	Not Available	Not Available	unknown_status
NCT01930149	Promoting Cholesterol Screening	No drug interventions	prevention	Not Available	completed
NCT03927196	Primary Prevention Program	No drug interventions	prevention	Not Available	completed