Graft-versus-host Disease (GVHD) (DBCOND0088786)

Identifiers

Synonyms
Graft vs. Host Disease / Graft vs. Host Disease (GvHD) / Graft-Versus-Host Disease / GvHD / Graft-Vs-Host Disease / Graft-vs-Host Disease (GVHD) / Graft Versus Host Disease (GVHD) / Graft vs Host Disease / Graft versus host disease / Graft-versus-host disease, unspecified / GVH disease / Graft-versus-host disease (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Antilymphocyte immunoglobulin (horse)
A primarily IgG immune globulin used to manage allograft rejection in renal transplant patients.
No drug targets
Cyclosporine
A steroid-sparing immunosuppressant used in organ and bone marrow transplants as well as inflammatory conditions such as ulcerative colitis, rheumatoid arthritis, and atopic dermatitis.
Etanercept
A protein therapy based on the binding fragment of the tumour necrosis factor alpha receptor used to treat severe rheumatoid arthritis and moderate to severe plaque psoriasis.
Methotrexate
An antineoplastic agent used the treatment of a wide variety of cancers as well as severe psoriasis, severe rheumatoid arthritis, and juvenile rheumatoid arthritis.
Posaconazole
A triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients.
Sirolimus
An mTOR inhibitor immunosuppressant used to prevent organ transplant rejections, treat lymphangioleiomyomatosis, and treat adults with perivascular epithelioid cell tumors.
Tacrolimus
A calcineurin inhibitor used to prevent organ transplant rejection and to treat moderate to severe atopic dermatitis.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT06598332
5-Azacytidine with Steroids for Gastrointestinal GVHD (5-AZA for GVHD)treatment0not_yet_recruiting
NCT02026934
CliniMACS® CD34+ Reagent System for Expanded Access UseNo drug interventionsNot AvailableNot Availableno_longer_available
NCT00128973
Evaluation of Patients With Immune Function AbnormalitiesNo drug interventionsNot AvailableNot Availablerecruiting
NCT06626737
Dapagliflozin in Allo-HCT for AGVHDprevention2not_yet_recruiting
NCT06615050
A Study of Tacrolimus/Methotrexate/Ruxolitinib Versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell Transplantationtreatment3not_yet_recruiting
NCT03064984
Blood Based Eyedrops From Different Sources in the Treatment of Severe KeratopathyNo drug interventionstreatmentNot Availableunknown_status
NCT03616184
Study of Ruxolitinib in Sclerotic Chronic Graft-Versus-Host Disease After Failure of Systemic Glucocorticoidstreatment2completed
NCT02953678
A Study of Ruxolitinib in Combination With Corticosteroids for the Treatment of Steroid-Refractory Acute Graft-Versus-Host Disease (REACH-1)treatment2completed
NCT03894488
Clinical Evaluation of the Application of the FilmArray GI Panel in Post-HSCT Diarrhea PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT03112603
A Study of Ruxolitinib vs Best Available Therapy (BAT) in Patients With Steroid-refractory Chronic Graft vs. Host Disease (GvHD) After Bone Marrow Transplantation (REACH3)treatment3completed
NCT03147742
An Expanded Access Program of Ruxolitinib for the Treatment of Graft-Versus-Host Disease Following Allogeneic Hematopoietic Stem Cell TransplantNot AvailableNot Availableapproved_for_marketing
NCT03139604
GRAVITAS-301: A Study of Itacitinib or Placebo in Combination With Corticosteroids for Treatment of Acute Graft-Versus-Host Diseasetreatment3completed
NCT02614612
Study of Itacitinib in Combination With Corticosteroids for the Treatment of Acute GVHDtreatment1completed
NCT05722912
Expanded Access of Ruxolitinib Cream to Treat a Single Patient With cGVHDNot AvailableNot Availableapproved_for_marketing
NCT05531786
Phase I/II Study of Pacritinib, A JAK2/IRAK1/CSF1R Inhibitor, in Refractory Chronic Graft-Versus-Host Disease (cGVHD) After Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)treatment1 / 2recruiting
NCT05621759
Cyclophosphamide, Abatacept, and Tacrolimus for the Prevention of GvHDprevention2recruiting
NCT04014790
RGI-2001 for the Prevention of Acute Graft-vs-Host Disease in Subjects Following Allogeneic Hematopoietic Stem Cell Transplantationprevention2completed
NCT02322190
Biomarkers in Acute Graft-Versus-Host Disease and Extracorporeal Photopheresis Added to Investigator Chosen Therapies of Steroid Refractory Acute GVHDtreatment2terminated
NCT03836690
Transfer of Effector Memory T Cells (Tem) Following Allogeneic Stem Cell TransplantationNo drug interventionstreatment1unknown_status
NCT00117702
Prevention of the Graft-Versus-Host-Disease in Patients After Stem Cell Transplantation With Tacrolimus and Everolimustreatment2 / 3terminated
NCT00810602
Vorinostat to Prevent Graft Versus Host Disease Following Reduced Intensity, Related Donor Stem Cell Transplanttreatment1 / 2completed
NCT02867384
Obinutuzumab in cGVHD After Allogeneic Peripheral Blood Stem Cell Transplantationtreatment2active_not_recruiting
NCT02876679
Cyclophosphamide Versus Anti-thymocyte Globulin for GVHD Prophylaxis After RIC Allo-SCTprevention2completed
NCT01940796
Phase I Trial of Brentuximab Vedotin for Refractory Chronic Graft-vs.-Host Disease (GVHD)treatment1terminated
NCT04448587
Sitagliptin for the Treatment of Grade 3-4 and Refractory Acute Graft-versus-host Diseasetreatment2unknown_status
NCT05780554
Post-transplantation Cyclophosphamide in Haploidentical Stem Cell Allografts Dose Reduction: 50 mg/kg vs 25 mg/kgpreventionNot Availableenrolling_by_invitation
NCT03369353
Precision Diagnostics in Inflammatory Bowel Disease, Cellular Therapy and Transplantation (The PREDICT Trial)No drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT01665677
Atorvastatin as GVHD Prophylaxis for Allogeneic Hematopoietic Cell Transplantationprevention2completed
NCT00350545
A Phase 2 Trial of Rituximab and Corticosteroid Therapy for Newly Diagnosed Chronic Graft Versus Host DiseasetreatmentNot Availablecompleted
NCT00314483
Evaluation of the Role of Mesenchymal Stem Cells in the Treatment of Graft Versus Host DiseaseNo drug interventionstreatment1 / 2unknown_status
NCT04473911
Haplo Peripheral Blood Sct In GVHD Preventiontreatment1active_not_recruiting
NCT01287078
Cyclosporine Inhalation Solution (CIS) in Lung Transplant and Hematopoietic Stem Cell Transplant Recipients for the Treatment of Bronchiolitis Obliterans Syndrometreatment2completed
NCT05333978
Optoacoustic Detection of Inflammation Using MSOT DeviceNo drug interventionsdiagnosticNot Availablerecruiting
NCT04558788
Cellular Stress Reactions During Graft-versus-host DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT04622956
GVHD Prophylaxis With Methotrexate in Haploidentical HCT Using Posttransplant Cyclophosphamideprevention1 / 2recruiting
NCT04337515
A Feasibility Study Using CLINIMACS® for Alpha/Beta T-Cell Depletion in Stem Cell TransplantNo drug interventionstreatmentNot Availablerecruiting
NCT02172937
Decidual Stromal Cells as Treatment for Acute Graft Versus Host Disease, a Phase 1-2 Studytreatment1 / 2unknown_status
NCT01393132
Comparative Study of Thymosin Beta 4 Eye Drops vs. Vehicle in the Treatment of Severe Dry Eyetreatment2completed
NCT01764100
Mesenchymal Stromal Cells (MSCs) for the Treatment of Graft Versus Host Disease (GVHD)No drug interventionstreatment1unknown_status
NCT02923375
A Study of CYP-001 for the Treatment of Steroid-Resistant Acute Graft Versus Host Diseasetreatment1completed
NCT00179075
Repository: Evaluation of Immunoregulatory Cells in Hematopoietic Stem Cell TransplantNo drug interventionsNot AvailableNot Availablecompleted
NCT05968170
TCRαβ/CD19 Depletion of Stem Cell Grafts for TransplantNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT00574470
Anti Cytokine Combination Therapy With Daclizumab and Infliximab for Treatment of Steroid Refractory Acute GVHDtreatment4completed
NCT00179049
Evaluation of Immunoregulatory Cells in Hematopoietic Stem Cell TransplantNo drug interventionsNot AvailableNot Availablecompleted
NCT01700036
A Pilot Study of Alpha-1-Antitrypsin (AAT) in Steroid Refractory Acute Graft vs Host Diseasetreatment2completed
NCT04922736
Patient Reported Outcomes With UVA-1 Therapy for Treatment of Sclerosing Skin DiseasesNo drug interventionstreatmentNot Availableenrolling_by_invitation
NCT01596218
Brentuximab Vedotin for Steroid Refractory GvHDtreatment1completed
NCT00759018
Prochymal Expanded Access Treatment for Pediatric Patients Who Have Failed Steroids for Acute GVHDNot AvailableNot Availableno_longer_available
NCT02385019
A Phase 1/2 Trial of Donor Regulatory T-cells for Steroid-Refractory Chronic Graft-versus-Host-DiseaseNo drug interventionstreatment1 / 2unknown_status
NCT00186641
High Dose Chemotherapy and Autologous Transplant for Breast CancerNo drug interventionstreatment2unknown_status
NCT05111834
IRENE-G Study: Impact of Resistance Exercise and Nutritional Endorsement on GvHD SymptomsNo drug interventionssupportive_careNot Availablerecruiting
NCT02478424
Extended Use of Cannabidiol for the Prevention of Graft-versus-host-diseaseprevention2unknown_status
NCT03731624
Diadenosine Polyphosphates and Mucin Associated With Ocular Surface DisordersNo drug interventionsNot AvailableNot Availableunknown_status
NCT00298324
Myfortic - Treatment for Extensive cGvHDtreatment3terminated
NCT03842696
Vorinostat for Graft vs Host Disease Prevention in Children, Adolescents and Young Adults Undergoing Allogeneic Blood and Marrow Transplantationprevention1 / 2recruiting
NCT00632658
Development and Validation of a Symptom Scale for Children With Chronic Graft-versus-Host DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT06160986
Horizons Chronic Graft-Versus-Host-Disease StudyNo drug interventionssupportive_careNot Availablerecruiting
NCT00128739
Treatment of Gastro-Intestinal and/or Hepatic Graft Versus Host Disease With Budesonide in Patients Following Peripheral Blood Stem Cell Transplantationtreatment3completed
NCT00106925
Long-term Evaluation and Follow-up Care of Patients Treated With Stem Cell TransplantsNo drug interventionsNot AvailableNot Availablerecruiting
NCT00144430
Pentostatin for High Risk and Refractory Chronic Graft Versus Host Disease in Childrentreatment2completed
NCT01175148
Atorvastatin for the Prophylaxis of Acute GVHD in Patients Undergoing Matched Sibling Allogeneic Transplantationprevention2completed
NCT00001748
HLA-Mismatched Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Hematological MalignanciesNo drug interventionstreatment1completed
NCT03136757
Analysis of Transcriptomic Profile of Graft-versus-host Disease (GHVD) After Allogeneic Grafting of Hematopoietic Stem CellsNo drug interventionsNot AvailableNot Availableunknown_status
NCT01512498
Vulvovaginal Graft Versus Host Disease (VV-GVHD) in Women Who Underwent Transplantation Before and After MenarcheNo drug interventionsNot AvailableNot Availablecompleted
NCT00189761
A Study to Assess Efficacy, Safety and Pharmacokinetics of a Tacrolimus New Oral Formulation (MR4) in BMT Recipientstreatment2completed
NCT00032279
Research Study of Visilizumab for Treatment of Glucocorticoid- Refractory Graft Versus Host Diseasetreatment2unknown_status
NCT02105766
Nonmyeloablative Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease and Beta-thalassemia in People With Higher Risk of Transplant Failuretreatment2recruiting
NCT01688466
Pomalidomide for Chronic Graft-versus-Host Diseasetreatment2completed
NCT05132166
A Randomized Phase II Study to Compare the Potential Long-Lasting Positive Effect of Decidual Stromal Cells to the Best Available Treatment in Graft Versus Host DiseaseNo drug interventionstreatment2active_not_recruiting
NCT04044365
Pediatric cGVHD Symptom ScaleNo drug interventionsNot AvailableNot Availablerecruiting
NCT00224874
Treatment for Acute Graft-Versus-Host Disease (BMT CTN 0302)treatment2completed
NCT03591874
Study of Brimonidine Tartrate Nanoemulsion Eye Drops in Patients With Ocular Graft-vs-Host Diseasetreatment3terminated
NCT03774082
Activity, Safety and Pharmacokinetics in Pediatric Subjects With Moderate and Severe Chronic Graft vs. Host Disease After Allogeneic Stem Cell Transplanttreatment2active_not_recruiting
NCT01851382
Collection of Saliva and/ or Peripheral Blood From Healthy Volunteers for ResearchNo drug interventionsNot AvailableNot Availablecompleted
NCT02506231
The Effect of Folinic Acid Rescue Following MTX GVHD Prophylaxis on Regimen Related Toxicity and Transplantation Outcomeprevention2 / 3unknown_status
NCT00001873
The Role of Cyclosporine in Blood Cell Transplants With T-Cell Add-Back for Blood CancersNo drug interventionstreatment2completed
NCT00000591
T-Cell Depletion in Unrelated Donor Marrow TransplantationNo drug interventionstreatment3completed
NCT00025662
Selective T-Cell Depletion to Reduce GVHD (Patients) Receiving Stem Cell Tx to Treat Leukemia, Lymphoma or MDSNo drug interventionstreatment2completed
NCT00388362
Sirolimus as Treatment of Steroid-Refractory or Steroid-Dependent Chronic Graft-Versus-Host Diseasetreatment2completed
NCT05236062
Impact of Exercise on the Complications of Corticosteroids in Patients With GVHD: the RESTART TrialNo drug interventionssupportive_careNot Availablerecruiting
NCT00048789
Extracorporeal Photopheresis to Treat Chronic Graft-Versus-Host DiseaseNo drug interventionstreatment2completed
NCT00563589
Mycophenolate Mofetil for the Prophylaxis of Graft-versus-host Disease in High Risk Allogeneic Stem Cell TransplantationpreventionNot Availableunknown_status
NCT00001144
Modified Bone Marrow Stem Cell Transplantation for Chronic Myelogenous LeukemiaNo drug interventionstreatment2completed
NCT05333367
MORPHEE : Mechanisms of Cell Death Induced by Extracorporeal PhotochemotherapyNo drug interventionsbasic_scienceNot Availableunknown_status
NCT03575767
Characteristics and Dynamics of TCR Repertoire in Patients With Hematological Malignancies After Allo-HSCTNo drug interventionsNot AvailableNot Availablecompleted
NCT06143501
Alterations in Intestinal Microbiota, Metabolites, and Immune Cells in Allo-HSCTNo drug interventionsNot AvailableNot Availablerecruiting
NCT01788501
Tacrolimus/Methotrexate Versus Cyclosporine/Methotrexate for Prophylaxis of Graft Versus Host Diseaseprevention2 / 3completed
NCT00001872
Cell Selection for Bone Marrow Transplants to Prevent Graft-Versus-Host-DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT01790568
Vorinostat Plus Tacrolimus & Methotrexate to Prevent Graft vs Host Disease Following Unrelated Stem Cell Transplantprevention2completed
NCT04070781
Itacitinib and Tocilizumab for Steroid Refractory Acute Graft Versus Host Diseasetreatment1terminated
NCT00195481
Study Evaluating Sirolimus in Kidney Transplant Recipients in Indiatreatment4completed
NCT02337595
Memory T-cell Infusion to Improve Immunity After TCR-alpha/Beta Depleted Hematopoietic Stem Cell TransplantationNo drug interventionsprevention1 / 2completed
NCT00409695
Thymoglobulin (ATG) Dose Finding Studytreatment1 / 2terminated
NCT05238155
Evaluation of the Impact of Reduced ImmunosuppressionNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT00670423
A Study Using Tacrolimus, Sirolimus and Bortezomib as Acute Graft Versus Host Disease (GVHD) Prophylaxis in Allogeneic Peripheral Blood Stem Cell (PBSC) Transplantationtreatment1completed
NCT01234623
Cord Blood Serum in the Treatment of Ocular Surface DiseasesNo drug interventionsNot AvailableNot Availablecompleted
NCT00001623
Bone Marrow Transplant Studies for Safe and Effective Treatment of LeukemiaNo drug interventionstreatmentNot Availablecompleted
NCT04227938
ALPN-101 in Steroid-resistant or Steroid-refractory Acute GVHDtreatment1terminated
NCT01972438
A Randomized, Controlled, Double-Masked, Clinical Trial of Autologous Serum Eye Drops for Severe Ocular Chronic Graft-versus-Host Disease (GVHD) in Hematopoietic Stem Cell Transplant (HSCT) PatientsNo drug interventionstreatment2terminated
NCT04131738
Baricitinib for the Prophylaxis of Graft-Versus-Host Disease After Peripheral Blood Hematopoietic Cell Transplantationtreatment1completed
NCT00136903
Safety and Efficacy Study of Adult Human Mesenchymal Stem Cells to Treat Acute Graft Versus Host Disease (GVHD)treatment2completed
NCT02891603
A Phase I/II GVHD Prevention Trial Combining Pacritinib With Sirolimus-Based Immune Suppressionprevention1 / 2completed
NCT06080490
Tacrolimus Blood Concentration and Transplant-related Outcomes in Pediatric HSCT RecipientsNot AvailableNot Availablerecruiting
NCT02411084
Study of BEGEDINA® vs "Conventional Treatment" for Treating Steroid-Resistant Acute GvHDtreatment3terminated
NCT01282879
Evaluation of Antifungal Prophylaxis on Graft-versus-host Disease (GVHD) Patientsprevention4terminated
NCT03474679
A Study of the Bruton's Tyrosine Kinase (BTK) Inhibitor Ibrutinib in Participants With Steroid Dependent/Refractory Chronic Graft Versus Host Disease (cGVHD)treatment3completed
NCT05018754
Treatment of Oral Mucositis Using Platelet Rich Fibrin TREATMENT OF ORAL MUCOSITIS USING PRFNo drug interventionsNot AvailableNot Availablecompleted
NCT00130754
Thymoglobuline in Non-myeloablative Allogeneic Stem-cell Transplantationprevention3completed
NCT05170347
oGVHD After Bone Marrow Transplantation: a Territory-wide CohortNo drug interventionsNot AvailableNot Availablerecruiting
NCT00167947
Study Evaluating Sirolimus in Kidney Transplant Recipients.treatment3completed
NCT02027805
Safety and Efficacy Study of T-Guard to Treat Steroid-resistant Acute GVHDtreatment1 / 2completed
NCT03093805
Topical Vitamin D in Acute Graft Versus Host Disease of the SkinNo drug interventionstreatmentNot Availablecompleted
NCT04752397
The Influence of Extracorporeal Photopheresis on Skin SclerosisNo drug interventionsNot AvailableNot Availablecompleted
NCT00102583
Cyclosporine Implant for Ocular Graft-Versus-Host Diseasetreatment1completed
NCT00001561
Active Immunization of Sibling Bone Marrow Transplant Donors Against Purified Myeloma Protein of the Recipient Undergoing Allogeneic Bone Marrow Transplantationtreatment3completed
NCT02396628
Ruxolitinib In GvHDNo drug interventionstreatment2terminated
NCT06568328
Chimeric Natural Killer Receptor-Universal T Cells for Refractory GVHDNo drug interventionstreatment1recruiting
NCT00146978
Intra-Arterial Catheter Directed Therapy for Severe Graft vs. Host Disease (GVHD)No drug interventionsNot Available1 / 2completed
NCT05167188
Evaluation of GvHD Damage on Medullary Mesenchymal Stem CellsNo drug interventionsNot AvailableNot Availablerecruiting
NCT00517907
Safety Study of Preimplantation Factor (PIF-1) to Treat Acute Steroid-Resistant Graft-Versus-Host Disease (GVHD)treatment1unknown_status
NCT01950507
Evaluation of Budesonide and How It Interacts With Antifungal Drugs in People With Gastrointestinal Graft-Versus-Host Diseasetreatment1terminated
NCT01206309
Immune Mediated Disorders After Allogeneic Hematopoietic Cell TransplantationNo drug interventionsNot AvailableNot Availablecompleted
NCT01042509
Combination of Alemtuzumab and Rituximab at Low-doses in Refractory Chronic Graft-Versus-Host DiseasetreatmentNot Availablecompleted
NCT03546556
18-FLT PET/MR Imaging to Predict Graft Failure and GVHD in Bone Marrow Transplant Patientsdiagnostic0terminated
NCT00001637
Immunosuppressive Preparation Followed by Blood Cell Transplant for the Treatment of Blood Cancers in Older AdultsNo drug interventionstreatment2completed
NCT03229200
Extended Treatment Protocol for Subjects Continuing to Benefit From Ibrutinib.treatment4enrolling_by_invitation
NCT01713400
Tacrolimus, Sirolimus and Ustekinumab vs. Tacrolimus and Sirolimus for the Prevention of Acute Graft-Versus-Host Diseasetreatment2completed
NCT00391170
Dexamethasone to Prevent Oral Chronic Graft-versus-Host Diseaseprevention2completed
NCT02737306
A Study of Acute Graft-Versus-Host Disease (GVHD) in Patients Undergoing Allogeneic Stem-Cell Transplantationtreatment2terminated
NCT04235036
Ibrutinib and Rituxan for Chronic GVHDtreatment2terminated
NCT02409134
Cognitive Function and Patient-Reported Quality of Life Outcomes Investigation in Patients Taking VorinostatNo drug interventionsNot AvailableNot Availablecompleted
NCT01994824
Preemptive Therapy of GVHDprevention2terminated
NCT01318330
Safety Study of Homeo-GH (Bone Marrow Derived Clonal Mesenchymal Stem Cell) to Treat Acute/Chronic Graft Versus Host Disease (GVHD)No drug interventionsNot Available1completed
NCT00548717
Sirolimus, Mycophenolate Mofetil and Bortezomib as Graft-Versus-Host Disease (GVHD) Prophylaxis After Reduced Intensity Conditioning (RIC) Hematopoietic Stem Cell Transplantationprevention2terminated
NCT00189748
A Study to Assess the Safety and Efficacy of a Tacrolimus New Oral Formulation (MR4) in BMT Patients-Extension-treatment2completed
NCT00031148
Keratinocyte Growth Factor to Prevent Acute GVHDNo drug interventionsprevention1 / 2completed
NCT03315741
The Safety and Tolerability of Pirfenidone for BOS After HCTtreatment1completed
NCT02172924
A Phase 2 Study Using Placenta Derived Decidual Stromal Cells for Graft Versus Host DiseaseNo drug interventionstreatment1 / 2unknown_status
NCT03963024
Treosulfan-TMI Conditioning and Rapamycin GvHD Prophylaxis Before Allo-HSCTtreatment1terminated
NCT02829216
Graft-versus-host Disease Associated MyelosuppressionNo drug interventionsNot AvailableNot Availableunknown_status
NCT00136396
Rituximab Therapy for Steroid-Refractory Chronic Graft Versus Host Diseasetreatment1 / 2completed
NCT00233896
Randomized Study of Oral Beclomethasone Dipropionate With Ten Days of Prednisone for Treatment of Gastrointestinal GVHDtreatment3completed
NCT03207958
Belimumab for Prevention of Chronic Graft-versus-Host Disease Following Allogeneic Hematopoietic Cell Transplantationtreatment1completed
NCT00228839
GVH 022P: Study Using Anti Tumor Necrosis Factor Antibody (Infliximab) for Treatment of Acute Graft Versus Host Diseasetreatment1completed
NCT05617625
CD34+ Enriched Transplants to Treat Myelodysplastic Syndrometreatment2suspended
NCT06450925
Vitamin A Supplementation in Allogeneic Stem Cell Transplantation.prevention2not_yet_recruiting
NCT02683525
Sitagliptin for Prevention of Acute Graft Versus-Host Disease After Allogeneic Hematopoietic Stem Cell Transplantationtreatment2completed
NCT01327625
Efficacy Study of Azithromycin-based Therapy for Bronchiolitis ObliteranstreatmentNot Availableterminated
NCT00001830
Donor Th2 Cells to Prevent Graft-Versus-Host Disease in Bone Marrow TransplantsNo drug interventionstreatment1completed
NCT00023530
Blood and Marrow Transplant Clinical Research NetworkpreventionNot Availablecompleted
NCT02770430
Mesenchymal Stem Cells as First Treatment Line for Resistant Acute Graft Versus Host Diseasetreatment2unknown_status
NCT00770757
CC-4047 (Pomalidomide) for Graft vs. Host Diseasetreatment2completed
NCT02319226
Toward Immune Biomarkers for Tolerance and GvHD in HumansNo drug interventionsNot AvailableNot Availableunknown_status
NCT05153226
GvHD Prophylaxis in Unrelated Donor HCT: Randomized Trial Comparing PTCY Versus ATGprevention3recruiting
NCT01221766
Impact of Adnexal Involvement of the Severity and Prognosis of Chronic Graft-versus-Host DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT00248365
Theralux Extracorporeal Photochemotherapy (ECP) in Patients With Extensive Chronic Graft Versus Host Disease (GvHD)No drug interventionstreatment1 / 2completed
NCT05718674
Photopheresis in GvHD After Hematopoietic Transplantation: Characteristics of the Procedure and of the Cell ProductNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT00044720
Study Evaluating Sirolimus in End Stage Renal Disease in High Risk Kidney Transplant RecipientsNot Available4completed
NCT04687982
Feasibility and Efficacy of Modified Donor Lymphocytes Infusion (CD45RA Negative Selected) After Haploidentical Transplantation With Post-transplantation Cyclophosphamide in Patients With Hematological Malignancies (ONC-2016-002).No drug interventionspreventionNot Availablecompleted
NCT00037531
Study Evaluating Sirolimus (Rapamune™) in Solid Organ Transplant RecipientsNot Available3completed
NCT01743131
Abatacept as GVHD Prophylaxis Phase 2prevention2completed
NCT00195273
Study Evaluating Sirolimus in Kidney Transplant Recipientstreatment3completed
NCT02945176
Safety and Performance Study of the ARGOS-IO System in Patients Undergoing Boston Keratoprosthesis ImplantationNo drug interventionsdiagnosticNot Availablecompleted
NCT01902576
Chronic GVHD Response Measures ValidationNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT05152160
Umbilical Cord Mesenchymal Stem Cells in the Treatment of Moderate/Severe Chronic Graft-versus-host DiseaseNo drug interventionstreatment1 / 2unknown_status
NCT00023491
Potential of Transplanted Stem Cells to Mature Into Salivary Gland and Cheek CellsNo drug interventionsNot AvailableNot Availablecompleted
NCT00578591
Rituximab for GVHDtreatment2withdrawn
NCT00035880
Study Comparing ABX-CBL (Monoclonal Antibody) Versus Atgam in Patients With Steroid Resistant Acute Graft Versus Host Diseasetreatment2 / 3completed
NCT02997280
Ruxolitinib for Steroid-refractory GVHDtreatment2completed
NCT00195429
A Study Comparing the Withdrawal of Steroids or Tacrolimus in Kidney Transplant Recipientstreatment4completed
NCT02525029
Study of Pregnyl as Adjunct Therapy for High-Risk or Refractory Acute GVHDsupportive_care1 / 2completed
NCT06133192
Steroids Versus ECP and Steroids as First-line Treatment of Grade II Acute GVHDtreatment2not_yet_recruiting
NCT00207792
Trial of Filgrastim Versus Placebo Following Allogeneic Bone Marrow Transplantationtreatment3unknown_status
NCT00032292
Research Study of Visilizumab for Treatment of Acute Graft Versus Host Diseasetreatment1 / 2completed
NCT04380740
Extended vs Short-term Abatacept Dosing for Graft Versus Host Disease Prophylaxistreatment2recruiting
NCT00186667
Sirolimus as Primary Therapy for the Treatment of Chronic Graft Versus Host DiseaseNo drug interventionstreatment2completed
NCT04678401
IS-free Treg HaploHCTtreatment1recruiting
NCT03434704
Peripheral Blood Stem Cell Transplantation From Family Haploidentical Donors in Patients With Myelodysplastic Syndrome and Acute Leukemia Under Primary Prophylaxis With Posaconazoletreatment2completed
NCT02064972
CEC Count Changes to Support GvHD Diagnosis.No drug interventionsNot AvailableNot Availablecompleted
NCT00195468
Study Comparing Cyclosporine Dose Reduction vs. Cyclosporine Elimination in Kidney Transplant Recipients Taking Sirolimustreatment4completed
NCT04728646
Evaluation of Dextenza in Patients With Ocular GVHD and Effects on Ocular Surface Disease Outcomestreatment4withdrawn
NCT01699412
Clinical Trial With Clobetasol and Dexamethasone for Topical Treatment of Oral Lesions of Chronic Graft-versus-host Diseasetreatment3completed
NCT04738981
Efficacy and Safety of UC-MSCs for the Treatment of Steroid-resistant aGVHD Following Allo-HSCTtreatment3completed
NCT00760981
A Pilot Study of Imatinib Mesylate in Steroid Refractory Chronic Graft Versus Host Diseasetreatment1completed
NCT02841995
A Study to Evaluate the Safety, Tolerability, and Activity of KD025 in Subjects With Chronic Graft Versus Host Diseasetreatment2completed
NCT04479995
Multidisciplinary Intervention In Chronic GVHDNo drug interventionssupportive_careNot Availableactive_not_recruiting
NCT03340155
Mechanisms of Action of Photo(Chemo)Therapy in Skin DiseasesNo drug interventionsotherNot Availableunknown_status
NCT03172455
Early Access Program Using Alpha 1 Antitrypsin Infusion for Patients With Steroid Refractory Acute GvHD After Hematopoietic Stem Cell Transplantation (HSCT)Not AvailableNot Availableno_longer_available
NCT06008808
Ruxolitinib for the Prophylaxis of Graft-Versus-Host Disease and Cytokine Release Syndrome After T-cell Replete Haploidentical Peripheral Blood Hematopoietic Cell Transplantationprevention1recruiting
NCT00563108
Basiliximab for the Treatment of Acute Graft-versus-host Disease After Allogeneic Stem Cell TransplantationtreatmentNot Availableunknown_status
NCT02398708
Comparison of Gut Microbiota, Inflammation and Symptoms Following Allogeneic HSCTNo drug interventionsNot AvailableNot Availablecompleted
NCT00655343
Acute Graft-Versus-Host Disease (aGvHD) Prophylaxis With ATG-Fresenius in Matched Unrelated Donor-Stem Cell Transplantation (MUD-SCT)prevention3completed
NCT00088543
Thymoglobulin to Prevent Acute Graft vs. Host Disease (GvHD) in Patients With Acute Lymphocytic Leukemia (ALL) or Acute Myelogenous Leukemia (AML) Receiving a Stem Cell TransplantNot AvailableNot Availablecompleted
NCT03983850
Optimizing PTCy Dose and Timingtreatment1 / 2recruiting
NCT04144036
Neihulizumab for Standard-Risk Acute Graft Versus Host Disease (GVHD)treatment1completed
NCT05263999
A Study of Itolizumab in Combination With Corticosteroids for the First-Line Treatment of Acute Graft Versus Host Disease (EQUATOR)treatment3recruiting
NCT05622318
De-escalated Cyclophosphamide (PTCy) and Ruxolitinib for Graft-versus-Host Disease (GVHD) Prophylaxistreatment2recruiting
NCT06392711
Dose-Escalation Trial of Mesenchymal Stromal Cells in Patients With Medical Xerostomiatreatment1recruiting
NCT05675930
A Study of Photobiomodulation (PBM) Therapy in People with Oral Graft-Versus-Host Disease (GVHD) After Stem Cell TransplantNo drug interventionstreatment2recruiting
NCT00489203
Beclomethasone Dipropionate in Preventing Acute Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant for Hematologic Cancersupportive_care2completed
NCT00002790
Prevention of Graft-Versus-Host Disease in Patients With Hematologic Malignancies Who Are Receiving a Bone Marrow Transplantsupportive_care1 / 2withdrawn
NCT00716690
Multi Donor Mismatched Stem Cell Transplantation (MDT)No drug interventionstreatment1 / 2unknown_status
NCT00749164
Allogeneic Mesenchymal Stem Cell for Graft-Versus-Host Disease TreatmentNo drug interventionstreatment1 / 2unknown_status
NCT01233921
Palifermin in Preventing Chronic Graft-Versus-Host Disease in Patients Who Have Undergone Donor Stem Cell Transplant for Hematologic Cancersupportive_careNot Availablecompleted
NCT04688021
A Single-arm Trial of Prophylactic Tocilizumab for Acute GVHD Prevention After Haploidentical HSCT.prevention2recruiting
NCT00492921
High-Dose Cyclophosphamide for Steroid Refractory GVHDsupportive_care2completed
NCT03204721
Prevention of GVHD in Patients Treated With Allogeneic SCT: Possible Role of Extracorporeal PhotophoresisNo drug interventionspreventionNot Availablecompleted
NCT02483702
Irradiated Blood Versus Non Irradiated Blood Transfusions in Craniosynostosis RepairNo drug interventionspreventionNot Availablecompleted
NCT00255684
Fludarabine, Cyclophosphamide, and Total-Body Irradiation Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients Who Are Undergoing a Donor Umbilical Cord Blood Transplant for Hematologic CancertreatmentNot Availableterminated
NCT03846479
Itacitinib for Low Risk GVHDtreatment2completed
NCT00093587
Antithymocyte Globulin and Cyclosporine in Preventing Graft-Versus-Host Disease in Patients Undergoing Chemotherapy With or Without Radiation Therapy Followed By Donor Stem Cell Transplant for Acute Lymphoblastic Leukemia or Acute Myeloid Leukemiasupportive_careNot Availableunknown_status
NCT00824954
Extracorporeal Photopheresis in Children and Young Adults With Refractory Acute Graft Versus Host DiseaseNo drug interventionstreatment2unknown_status
NCT00006054
Allogeneic Bone Marrow Transplantation in Patients With Primary ImmunodeficienciestreatmentNot Availableterminated
NCT03361254
Cryopreservation of White Blood Cells Before Their UVA Irradiation for Graft Versus Host Disease TreatmentNo drug interventionstreatmentNot Availableunknown_status
NCT00006451
Bone Marrow Transplantation in Treating Patients With Leukemiatreatment3withdrawn
NCT02824653
Allogenic Bone Marrow Mesenchymal Stem Cells Infusion in Patients With Steroid-refractory GVHDNo drug interventionstreatment1 / 2completed
NCT00144677
Sirolimus With Tacrolimus for Graft-vs-Host Disease Prophylaxis After Un-Related Stem Cell Transplantationprevention2completed
NCT00043147
Beclomethasone Plus Prednisone in Treating Patients With Graft-Versus-Host Diseasesupportive_care3completed
NCT06238245
Combination of ATG-based Conditioning Regimen and PTCy for GVHD Prevention in Allo-HSCT After PD-1 Blockadeprevention2not_yet_recruiting
NCT00923845
Low-Intensity Stem Cell Transplantation With Multiple Lymphocyte Infusions to Treat Advanced Kidney Cancertreatment2completed
NCT00366145
Efficacy and Safety of Adult Human Mesenchymal Stem Cells to Treat Steroid Refractory Acute Graft Versus Host Disease (GVHD)treatment3completed
NCT00003398
Bone Marrow Transplantation in Treating Patients With Hematologic Cancertreatment4completed
NCT02248597
Donor Stem Cell Transplant Followed by Cyclophosphamide in Treating Patients With Hematological Diseasestreatment2completed
NCT01309997
Imatinib and Rituximab in Treating Cutaneous Sclerosis in Patients With Chronic Graft-Versus-Host Diseasetreatment2completed
NCT00450983
Donor Peripheral Stem Cell Transplant and Donor Natural Killer Cell Transplant After Total-Body Irradiation, Thiotepa, Fludarabine, and Muromonab-CD3 in Treating Patients With Leukemia or Other Blood Diseasestreatment2terminated
NCT00079183
Sirolimus as Secondary Therapy in Chronic Graft-Versus-Host Disease Not Responding To Prior Treatmentsupportive_care2completed
NCT00003661
Chemotherapy, Radiation Therapy, and Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancertreatment2completed
NCT00096161
Pentostatin and Lymphocyte Infusion in Preventing Graft Rejection in Patients Who Have Undergone Donor Stem Cell Transplanttreatment2completed
NCT00109993
Campath-1H + FK506 and Methylprednisolone for GVHDsupportive_care2completed
NCT00943293
Minor Histocompatibility Vaccination After Allogeneic Stem Cell Transplantation for Advanced Hematologic Malignanciestreatment1terminated
NCT03419078
Nutrition and Outcomes of Hematopoietic Cell Transplantation (HCT)No drug interventionsNot AvailableNot Availablecompleted
NCT00577278
A Phase II Study of Allo-HCT for B-Cell NHL Using Zevalin, Fludarabine and Melphalantreatment2completed
NCT02203578
Romidepsin in Treating Patients With Steroid-Refractory Graft-versus-Host Diseasesupportive_careNot Availableterminated
NCT00005988
Bone Marrow Transplantation With Specially Treated Bone Marrow in Treating Patients With Hematologic Cancer That Have Not Responded to Previous Therapytreatment1completed
NCT01273207
Extension Study (Extended Access) of Cyclosporine Inhalation Solution (CIS) in Lung Transplant and Hematopoietic Stem Cell Transplant Recipients for the Treatment of Bronchiolitis Obliteranstreatment2completed
NCT00382109
Tacrolimus and Methotrexate With or Without Sirolimus in Preventing Graft-Versus-Host Disease in Young Patients Undergoing Donor Stem Cell Transplant for Acute Lymphoblastic Leukemia in Complete Remissiontreatment3completed
NCT01379209
Intravenous Administration of RGI-2001 in Patient Undergoing Allogenic Hematopoietic Stem Cell Transplantation (AHSCT)treatment1 / 2completed
NCT00609609
Photopheresis for the Treatment of Acute Graft Versus Host Diseasetreatment2completed
NCT02109809
Low-Dose Total Lymphoid Irradiation in Treating Patients With Refractory Chronic Graft-versus-Host Disease After Donor Stem Cell TransplantNo drug interventionssupportive_careNot Availableterminated
NCT00002456
Graft-Versus-Host Disease Prevention in Treating Patients Who Are Undergoing Bone Marrow Transplantationsupportive_care3completed
NCT00006056
Pilot Study of Unrelated Donor Hematopoietic Stem Cell Transplantation in Patients With Life Threatening Hemophagocytic DisorderstreatmentNot Availableunknown_status
NCT00003056
Prevention of Graft-Versus-Host Disease in Patients With Advanced Leukemia or Lymphoma Who Are Eligible for Peripheral Stem Cell Transplantationsupportive_care3terminated
NCT00360685
Tacrolimus and Mycophenolate Mofetil (MMF) in GVHD Prophylactic Regimen Compared to Tacrolimus and Methotrexate (MTXtreatmentNot Availablecompleted
NCT00373815
Everolimus in Combination With Cyclosporine A and Prednisolone for the Treatment of Graft Versus Host Diseasetreatment1terminated
NCT00544115
Donor Peripheral Stem Cell Transplant in Treating Patients With Advanced Hematologic Cancer or Other Disorderstreatment2active_not_recruiting
NCT00089037
Sirolimus, Tacrolimus, and Methotrexate in Preventing Acute Graft-Versus-Host Disease in Patients With Hematologic Cancer Who Are Undergoing Donor Stem Cell Transplantationsupportive_care1 / 2completed
NCT00004232
Bone Marrow and Peripheral Stem Cell Transplantation in Treating Patients With Hematologic Cancersupportive_care1completed
NCT05694832
Expressive Writing in GVHDNo drug interventionstreatment0enrolling_by_invitation
NCT00005852
Bone Marrow Transplantation in Treating Patients With Severe Aplastic Anemia or Rejection of Previous Bone Marrow Transplanttreatment2terminated
NCT04231500
The Skin Microbiome in Graft Versus Host DiseaseNo drug interventionsNot AvailableNot Availablerecruiting
NCT00054600
Safety and Efficacy Study of Photopheresis With UVADEX to Prevent Graft-versus-Host Diseaseprevention2completed
NCT02867800
Abatacept for GVHD Prophylaxis After Hematopoietic Stem Cell Transplantation for Pediatric Sickle Cell Diseasetreatment1completed
NCT00346359
Fludarabine and Busulfan Followed by Donor Peripheral Stem Cell Transplant and Antithymocyte Globulin, Tacrolimus, and Methotrexate in Treating Patients With Myeloid Cancertreatment2completed
NCT00007059
Study of the Pharmacokinetics of Mycophenolate Mofetil in Patients Who Have Undergone Orthotopic Liver TransplantationtreatmentNot Availablecompleted
NCT00056875
Recombinant Human Keratinocyte Growth Factor in Unrelated and Related TransplantsNo drug interventionsprevention1 / 2completed
NCT01596075
Safety and Efficacy of Cannabidiol for Grade I/II Acute Graft Versus Host Disease (GVHD) After Allogeneic Stem Cell Transplantationtreatment1 / 2unknown_status
NCT02379442
Early Treatment of Acute Graft Versus Host Disease With Bone Marrow-Derived Mesenchymal Stem Cells and CorticosteroidsNo drug interventionstreatment1 / 2terminated
NCT04342442
Identification of Novel Targetable Kinases in SR-a GvHDNo drug interventionsNot AvailableNot Availablecompleted
NCT00900406
Collecting and Storing Tissue and DNA Samples From Patients Undergoing a Donor Stem Cell TransplantNo drug interventionsNot AvailableNot Availablecompleted
NCT04014413
Safety and Efficacy of Fecal Microbiota TransplantationNo drug interventionstreatmentNot Availablerecruiting
NCT00361413
Alefacept for Prevention of Graft Versus Host Disease (GVHD)prevention3terminated
NCT02086513
Phase I Trial of LDE225 for Steroid-refractory Chronic GVHD After Allogeneic HSCTtreatment1terminated
NCT00813618
Study of MEDI 507 in the Treatment of Pediatric Patientstreatment1completed
NCT00376519
Umbilical Cord Blood T-Regulatory Cell Infusion Followed by Donor Umbilical Cord Blood Transplant in Treating Patients With High-Risk Leukemia or Other Hematologic Diseasestreatment1terminated
NCT00005641
Removal of T Cells to Prevent Graft-Versus-Host Disease in Patients Undergoing Bone Marrow Transplantationtreatment2terminated
NCT00608517
Treatment of Single or Double Umbilical Cord Trans + Graft-versus-host Disease (GVHD) Prophylaxis w/ Tacrolimus & Mycophenolate MofetiltreatmentNot Availableterminated
NCT00639717
Addition of Etanercept and Extracorporeal Photopheresis (ECP) to Standard Graft-Versus-Host Disease (GVHD) Prophylaxis in Stem Cell Transplantprevention2completed
NCT03818334
Post Transplant Cyclophosphamide in Matched Unrelated Donor Stem Cell Transplantation for Hematological Malignanciesprevention2 / 3recruiting
NCT04503616
Cyclophosphamide, Abatacept, and Tacrolimus for GvHD Preventionprevention1 / 2active_not_recruiting
NCT00489216
Efalizumab in Treating Patients With Graft-Versus-Host Disease of the Skin That Did Not Respond to Previous Steroidssupportive_careNot Availableterminated
NCT01522716
Mesenchymal Stromal Cells as Treatment of Chronic Graft-versus-host Diseasetreatment1terminated
NCT02976558
The Influence of TaKeTiNa Music Therapy, Traditional Chinese Acupuncture and Clown Theatrical Performance on Quality of Life and the Therapeutic Process of Patients Undergoing Allogenic Stem Cell TransplantationNo drug interventionstreatmentNot Availableterminated
NCT00438958
Sibling Donor Peripheral Stem Cell Transplant or Sibling Donor Bone Marrow Transplant in Treating Patients With Hematologic Cancers or Other Diseasestreatment3completed
NCT00074035
Pentostatin in Treating Patients With Refractory Chronic Graft-Versus-Host Diseasesupportive_care2completed
NCT02174263
Tocilizumab for Chronic Graft-versus-Host Disease Treatmentsupportive_care2withdrawn
NCT00589563
Sirolimus, Tacrolimus, and Antithymocyte Globulin in Preventing Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant For Hematological Cancersupportive_care2completed
NCT02849886
T Lymphocytes (LT) Expressing iCASP9 and ΔCD19 in Allogeneic Haematopoietic Transplantation.prevention1 / 2unknown_status
NCT00201786
Phase II Trial of Pentostatin in Steroid Refractory Acute Graft Versus Host Diseasetreatment2completed
NCT02151539
Prospective Outcomes of Second-Line Therapy in Acute Graft-Versus-Host Study Including ECP (POSTAGE)No drug interventionsNot AvailableNot Availableterminated
NCT01222039
Multicenter Clinical Trial for the Evaluation of Mesenchymal Stem Cells From Adipose Tissue in Patients With Chronic Graft Versus Host Disease.No drug interventionstreatment1 / 2completed
NCT00141739
Study of Etanercept for the Prevention of Complications Resulting From Hematopoietic Stem Cell Transplantation (HSCT)treatment2completed
NCT02663622
Phase II Trial of Efprezimod Alfa (CD24Fc, MK-7110) for the Prevention of Acute Graft-Versus-Host Disease (GVHD) Following Myeloablative Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) (MK-7110-002)treatment2completed
NCT02956122
A Phase 2/3 Study of GLASSIA for the Treatment of Acute GvHDtreatment2 / 3terminated
NCT06304025
Sequential Administration of WJ-MSCs for the Treatment of GvHD Refractory to Second Line Treatmenttreatment1 / 2not_yet_recruiting
NCT02144025
Prevention of Ocular Graft-Versus-Host Disease With Topical Cyclosporine in Recipients of Allogeneic HSCTprevention2completed
NCT00555048
Alemtuzumab, Busulfan, and Cyclophosphamide Followed By a Donor Stem Cell Transplant in Treating Patients With Hematologic Cancertreatment1 / 2terminated
NCT05186857
Metabolome and Microbiome Impact on Acute GVHD in Recipients of Hematopoietic TransplantNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT00986557
T-Lymphocyte Infusion or Standard Therapy in Treating Patients at Risk of Cytomegalovirus Infection After a Donor Stem Cell Transplantsupportive_care2unknown_status
NCT03147157
The Effect of Human Leukocyte Antigen Macthing on Guiding Tacrolimus Regimen After Liver TransplantationNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT01810926
T&B Depletion Non Malignantprevention2unknown_status
NCT01111526
Histone Deacetylase Inhibitor LBH589 in Addition to Corticosteroids in Patients With Acute Graft Versus Host Disease (GVHD)treatment1 / 2completed
NCT00055666
Compassionate Use of Beclomethasone in Treating Patients With Graft-Versus-Host Disease of the Gastrointestinal Tractsupportive_careNot Availablecompleted
NCT01549665
Umbilical Cord Blood-derived Mesenchymal Stem Cells for the Treatment of Steroid-refractory Acute or Chronic Graft-versus-host-diseaseNo drug interventionstreatment1 / 2unknown_status
NCT00282282
Tacrolimus and Sirolimus as Prophylaxis After Allogenic Non-myeloablative Peripheral Blood Stem Cell Transplantationtreatment2completed
NCT02176031
Phase II Trial of Natalizumab + Prednisone for Initial Therapy of Acute GI GVHDtreatment2completed
NCT06423131
Prospective Clinical Trial for Children With TCRαβ Depleted vs Traditional Haplo Identicle HSCTNo drug interventionstreatmentNot Availablerecruiting
NCT02942173
CD45RA Depleted T-cell Infusion for Prevention of Infections After TCRab/CD19-depleted Allo-HSCTNo drug interventionsprevention2 / 3completed
NCT03605927
CD40-L Blockade for Prevention of Acute Graft-Versus-Host Diseaseprevention1completed
NCT03102060
Gluten Free Diet in Preventing Graft Versus Host Disease in Patients Undergoing Donor Stem Cell TransplantNo drug interventionspreventionNot Availableterminated
NCT03395860
Low Dose ATG Plus Low Dose PTCy as GVHD Prophylaxis in Haplo-HSCTNo drug interventionstreatment2unknown_status
NCT00725062
Donor T Cells in Treating Patients With High-Risk Hematologic Cancer Undergoing Donor Peripheral Blood Stem Cell TransplantNo drug interventionstreatment1terminated
NCT04792580
The Effects and Safety of 5% Lifitegrast Ophthalmic Solution in Subjects With Dry Eye Disease in Ocular Graft-versus-Host Diseasetreatment0completed
NCT01616680
Brentuximab Vedotin in Treating Patients With Steroid-Resistant Acute Graft-Versus-Host Diseasesupportive_care2withdrawn
NCT00720629
Visilizumab for the Prevention of Graft-versus-Host Disease After Allogeneic Hematopoietic Cell Transplantationprevention2terminated
NCT02359929
BMT Autologous MSCs for GvHDtreatment1completed
NCT01754389
Standard of Care vs. Bortezomib in Graft-Versus Host Disease After Hematopoietic Stem Cell Transplanttreatment2completed
NCT00914940
Selective Depletion of CD45RA+T Cells From Allogeneic Peripheral Blood Stem Cell Grafts for the Prevention of GVHDtreatment2terminated
NCT03395340
Topical Ruxolitinib for Cutaneous Chronic Graft Versus Host Disease (cGVHD)treatment2terminated
NCT02812940
Single-centre Study of Everolimus as GvHD Prophylaxis After Post-Transplantation Cyclophosphamide After Allogeneic SCTprevention2completed
NCT00912067
Ocular Graft Versus Host Disease After Hematopoietic Stem Cell Transplantation in AdultsNo drug interventionsNot AvailableNot Availableunknown_status
NCT01991301
Carfilzomib for the Prevention of Graft Versus Host DiseaseNo drug interventionstreatment1unknown_status
NCT04838704
Ruxolitinib With Calcineurin and Methotrexate vs. Calcineurin Plus Methotrexate and Mycophenolate Mofetil as Graft Versus Host Disease Prophylaxis for HLA-haploidentical Hematopoietic Stem Cell Transplantationprevention4recruiting
NCT00450268
Dendritic Cells in Patients Following Allogeneic Hematopoietic Stem Cell TransplantationNo drug interventionsNot AvailableNot Availableunknown_status
NCT00014469
Combination Chemotherapy Followed by Bone Marrow Transplantation in Treating Patients With Advanced Hematologic Cancertreatment2completed
NCT00623012
Rapamycin for Prevention of Chronic Graft-Versus-Host Diseasetreatment1 / 2terminated
NCT04669210
PTCy and Ruxolitinib vs PTCy, Tacrolimus and MMF in MUD and Haploidentical HSCTprevention2active_not_recruiting
NCT00255710
Cyclophosphamide and/or Mycophenolate Mofetil With or Without Tacrolimus in Treating Patients Who Are Undergoing a Donor Bone Marrow or Peripheral Stem Cell Transplant for Hematologic Cancersupportive_care1completed
NCT02891395
Efficacy and Safety of Nilotinib in Patients With a Chronic Disease of the Graft Against the Hosttreatment2completed
NCT01369914
The Natural History of Graft-Versus-Host Disease in the EyesNo drug interventionsNot AvailableNot Availablecompleted
NCT00600314
Measurements of Resting Energy Expenditure in Patients With or at Risk of Developing Graft Versus Host DiseaseNo drug interventionsNot AvailableNot Availableunknown_status
NCT01460914
Outcomes of Cutaneous T-Cell Lymphoma and Graft-Versus-Host Disease With Extracorporeal Photopheresis TreatmentNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT00146614
Tacrolimus, Sirolimus and Methotrexate as Graft Versus Host Disease Prophylaxis After Blood Stem Cell Transplantationtreatment2completed
NCT00003414
Graft-Versus-Host Disease in Treating Patients With Recurrent or Refractory Lymphoma or Hodgkin's Diseasetreatment3completed
NCT00004255
Treatment of Bone Marrow to Prevent Graft-Versus-Host Disease in Patients With Acute or Chronic Leukemia Undergoing Bone Marrow Transplantationtreatment2 / 3completed
NCT00454155
Study of Opebacan in Patients Undergoing Myeloablative Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)prevention1 / 2terminated
NCT00006055
Autologous Peripheral Blood Stem Cell Transplantation in Patients With Life Threatening Autoimmune DiseasestreatmentNot Availableunknown_status
NCT00081055
OTI-010 for Graft-Versus-Host Disease Prophylaxis in Treating Patients Who Are Undergoing Donor Peripheral Stem Cell Transplantation for Hematologic Malignanciessupportive_care2withdrawn
NCT00179855
Extracorporeal Photopheresis for Acute Graft Versus Host DiseaseNo drug interventionstreatment2 / 3unknown_status
NCT00075023
Effectiveness of Topical Thalidomide to Treat Chronic Graft-Versus-Host-Disease Related Stomatitistreatment2terminated
NCT05158608
Comparison of PT-Cy at a Dose of 25 mg/kg/Day and PT-Cy at a Dose of 50 mg/kg/Day in GVHD Prophylaxisprevention3not_yet_recruiting
NCT00993343
Randomized Trial Comparing Sirolimus and Tacrolimus Versus Cyclosporine and Methotrexate as Graft-versus-host Disease (GVHD) Prophylaxis After Allogeneic Stem Cell Transplantationprevention3completed
NCT03438643
Dynamic of Immunocompetent Populations in Patients Treated With Extracorporeal Photopheresis in Chronic Graft Versus Host DiseaseNo drug interventionsNot AvailableNot Availablerecruiting
NCT02145403
Phase 1/2 Study of Carfilzomib for the Prevention of Relapse and GVHD in Allo-HCT for Hematologic Malignanciestreatment1 / 2completed
NCT06321003
SYsteMatical Trained learnIng aLgorithms for Oral carcInogenesiS Interpretation by Optical Coherence TomographyNo drug interventionsNot AvailableNot Availablerecruiting
NCT05866302
Parametric Response Mapping (PRM) for the Detection of Chronic Lung Injury in Hematopoietic Cell Transplant RecipientsNo drug interventionsNot AvailableNot Availablerecruiting
NCT00524784
Open-Label Study Designed to Evaluate the Safety and Preliminary Efficacy of ApoCell for the Prevention of Acute GvHDNo drug interventionsprevention1 / 2unknown_status
NCT02660684
Study to Assess the Safety and Efficacy of Tacrolimus (Prograf Capsule/Injection) and Methotrexate (MTX) Combination Therapy for Prevention of Graft Versus Host Disease (GVHD) in Patients Who Received Peripheral Hematopoietic Stem Cell Transplantation From a Sibling Donortreatment4completed
NCT04660487
Relationship Between "FODMAPs" and "GVHD"No drug interventionsNot AvailableNot Availablerecruiting
NCT05621733
A PMS of Jakavi® in Patients With Steroid-Refractory Graft-versus-Host Disease (SR-GvHD) in KoreaNo drug interventionsNot AvailableNot Availablerecruiting
NCT00002833
Peripheral Stem Cell Transplantation Plus Filgrastim in Treating Patients With Acute or Chronic Myelogenous Leukemiatreatment2completed
NCT00506233
Feasibility Study of Collecting Multicenter Chronic GVHD DataNo drug interventionsNot AvailableNot Availablecompleted
NCT00616954
A Study to Evaluate the Effect of ATG-F on Engraftment, Graft Versus Host Disease (GVHD) and Graft Versus Leukemia (GVL) Effect in Haplo-identical SCTNo drug interventionstreatment3terminated
NCT00017654
Study of Allogeneic Bone Marrow and T-Cell Depleted, CD34+ Peripheral Blood Stem Cell Transplantation in Patients With Aplastic AnemiatreatmentNot Availableunknown_status
NCT02707354
Early Detection of Mucosal Abnormalities in Graft-versus-host DiseaseNo drug interventionsdiagnosticNot Availablecompleted
NCT00611351
Busulfan, Cyclophosphamide, & Antithymocyte Globulin Followed by Stem Cell Transplant in Treating Hematologic Cancertreatment2completed
NCT00948753
Maraviroc in Patients Undergoing Non-Myeloablative Allogeneic Stem-Cell Transplantationtreatment1 / 2completed
NCT01487577
Pharmacokinetics-based Mycophenolate Mofetil Dosing for GVHD Preventiontreatment2completed
NCT01174277
Pilot Study: Patients With Chronic Active Graft Versus Host Disease That Have Failed or Not Tolerated Standard Therapy.No drug interventionsNot AvailableNot Availablecompleted
NCT00006747
Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Mantle Cell Lymphomatreatment2completed
NCT03414645
Topical Fibrinogen-Depleted Human Platelet Lysate in Patients With Dry Eye Secondary to Graft vs. Host Diseasetreatment1 / 2completed
NCT01044745
Rituximab in Preventing Acute Graft-Versus-Host Disease in a Donor Stem Cell Transplant for Hematologic Cancertreatment2terminated
NCT01066598
A Study of Rituximab Combined With Prednisone for the Initial Treatment of Chronic Graft Versus Host Disease (cGVHD)treatment2terminated
NCT00827398
Treatment of Steroid Resistant GVHD by Infusion MSCNo drug interventionstreatment1 / 2completed
NCT03148197
Changes in the Gut Microbiota of Patients Undergoing Allogeneic Stem Cell Transplantation (COLLECT)No drug interventionsNot AvailableNot Availableunknown_status
NCT03192397
Chemotherapy, Total Body Irradiation, and Post-Transplant Cyclophosphamide in Reducing Rates of Graft Versus Host Disease in Patients With Hematologic Malignancies Undergoing Donor Stem Cell Transplanttreatment1 / 2active_not_recruiting
NCT00562497
Efficacy and Safety of Prochymal® Infusion in Combination With Corticosteroids for the Treatment of Newly Diagnosed Acute Graft Versus Host Disease (GVHD)treatment3completed
NCT03339297
An Open-Label Study of Defibrotide for the Prevention of Acute Graft-versus-Host-Disease (AGvHD)treatment2completed
NCT02178683
Tacrolimus and Mycophenolate Mofetil as Post-Grafting Immunosuppressiontreatment3unknown_status
NCT00010283
Beclomethasone in Treating Patients With Graft-Versus-Host Disease of the Esophagus, Stomach, Small Intestine, or Colonsupportive_care1 / 2completed
NCT00408928
Study on the Safety and Effectiveness of VELCADE® in the Treatment of Graft-Versus-Host Diseasetreatment2completed
NCT00290628
Donor Umbilical Cord Blood Transplant in Treating Patients With Hematologic CancertreatmentNot Availableterminated
NCT00806728
Study of MEDI-507 in With Steroid-Resistant Acute Graft-Versus-Host Diseasetreatment1completed
NCT03297528
Chemotherapy and DLI for Prevention of Second Relapse in Patients With Relapsed Acute Leukemia After AllotransplantNo drug interventionsprevention2unknown_status
NCT00501228
Tissue Repair in Stem Cell Transplant RecipientstreatmentNot Availableterminated
NCT00723593
Natural History and Pathophysiology of Gastrointestinal Graft-versus-Host DiseaseNo drug interventionsNot AvailableNot Availablewithdrawn
NCT00004878
Donor Lymphocytes to Prevent Graft-Versus-Host Disease in Patients With Chronic Myeloid Leukemiasupportive_care2withdrawn
NCT00189488
Trial to Evaluate Palifermin in the Reduction of Acute Graft Versus Host Disease in Patients With Hematologic Malignancies Undergoing Allogeneic Marrow/Peripheral Blood Progenitor Cell (PBPC) Transplantationtreatment2completed
NCT02799888
Maraviroc-Based GVHD Prophylaxis in HLA-Unrelated and HLA-Mismatched Related Transplantationprevention2unknown_status
NCT03124056
Clinical and Biomarker Study of the Efficacy of Extracorporeal Photopheresis in Graft-versus-host DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT01616056
Bandage Lenses in Treating Patients With Ocular Graft-Versus-Host DiseaseNo drug interventionssupportive_care2completed
NCT05808985
Intestinal Microbiome-based Research for the Prevention of Acute GVHDprevention2recruiting
NCT00898885
Analysis of the Clinical and Histological Correlation of Oral Graft-Versus-Host-Disease (GVHD)No drug interventionsNot AvailableNot Availablecompleted
NCT06279585
Physical Therapy in Patients Undergoing Allo-HSCT With cGVHDNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT00265837
Laboratory-Treated Donor Bone Marrow in Treating Patients Who Are Undergoing a Donor Bone Marrow Transplant for Hematologic CancerNo drug interventionstreatment3completed
NCT00775632
Alemtuzumab and Cyclosporine for the Prevention of Graft vs Host Disease After Stem Cell Transplantstreatment2completed
NCT01116232
Sirolimus, Tacrolimus, Thymoglobulin and Rituximab as Graft-versus-Host-Disease Prophylaxis in Patients Undergoing Haploidentical and HLA Partially Matched Donor Hematopoietic Cell Transplantationsupportive_care2terminated
NCT00253552
G-CSF-Treated Donor Bone Marrow Transplant in Treating Patients With Hematologic DisorderstreatmentNot Availableterminated
NCT02386800
CINC424A2X01B Rollover Protocoltreatment4recruiting
NCT03357159
Anti T-lymphocyte Immunoglobulin With Post Transplant Cyclophosphamide to Prevent GVHD Post Allogeneic Transplantationtreatment2recruiting
NCT03128359
High Dose Cyclophosphamide, Tacrolimus, and Mycophenolate Mofetil in Preventing Graft Versus Host Disease in Patients With Hematological Malignancies Undergoing Myeloablative or Reduced Intensity Donor Stem Cell Transplantsupportive_care2completed
NCT00003270
Chemotherapy, Radiation Therapy, and Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancertreatment2completed
NCT06252870
Study Testing Two Conditioning Regimen With a Single Prophylaxis of GVHD by Cyclophosphamide and Methotrexate Post-transplant in Patients Eligible for Matched-donor Allograft Transplantationtreatment2recruiting
NCT01002742
Acute Graft-versus-Host Disease Treatment (BMT CTN 0802)treatment3completed
NCT03602599
Chronic Graft-versus-Host Disease in the Oral Cavity of Patients Following Allogeneic Hematopoietic Stem Cell Transplant and Including Healthy ControlsNo drug interventionsNot AvailableNot Availablerecruiting
NCT00201799
Infliximab for the Prevention of Graft-versus-Host Disease Following Allogenic Hematopoietic Stem Cell Transplantationprevention2completed
NCT00353106
Experience of Having Chronic Graft-Versus-Host DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT01857336
G-CSF Moblized Peripheral Harvest for Poor Engraftment After Stem Cell TransplantationNo drug interventionstreatmentNot Availablecompleted
NCT00141713
The Use of Etanercept (Enbrel®) in the Treatment of Acute Graft-Versus-Host Diseasetreatment2completed
NCT03727113
Optimization of Antibiotic Treatment in Hematopoietic Stem Cell ReceptorsNo drug interventionsNot AvailableNot Availablecompleted
NCT02342613
Adoptive Immunotherapy With Activated Marrow Infiltrating Lymphocytes and Cyclophosphamide Graft-Versus-Host Disease Prophylaxis in Patients With Relapse of Hematologic Malignancies After Allogeneic Hematopoietic Cell TransplantationNo drug interventionstreatment1completed
NCT00054613
Safety and Efficacy Study of Photopheresis Plus Standard Therapy to Treat Chronic Graft-versus-Host Diseasetreatment2completed
NCT00675441
Lenalidomide (Revlimid®) as Second Line Therapy in Patients With Chronic Graft-Vs-Host Disease (GVHD)treatment2terminated
NCT06200441
Correlation of Serum Gasdermin-D and NLRP-3 Inflammasome Levels With GVHD Biomarkers and Endothelial Damage Markers in Graft-Versus-Host DiseaseNo drug interventionsNot AvailableNot Availablerecruiting
NCT01135641
Study of First Line Treatment of Chronic Graft Versus Host Disease With the Association of Ciclosporine, Corticosteroids and Rituximab (Protocol R-GVHD)treatment2completed
NCT03456817
HIgh Dose Thymoglobulin Instead of Cyclosporine With a Low Dose of Thymoglobulin for GVHD Prophylaxistreatment2recruiting
NCT01385124
Cannabidiol for Graft Versus Host Disease (GVHD) Prophylaxis in Allogeneic Stem Cell Transplantationprevention1 / 2unknown_status
NCT00031824
Hydroxychloroquine in Treating Patients With Newly Diagnosed Chronic Graft-Versus-Host Diseasesupportive_care3completed
NCT00096096
Tacrolimus and Mycophenolate Mofetil in Preventing Acute Graft-Versus-Host Disease in Patients With Advanced Hematologic Cancer Who Are Undergoing Donor Stem Cell Transplantationsupportive_care2completed
NCT05856058
To Assess SHR0302 Oral Solutions and Tablets in Healthy Subjects Clinical Studies of Relative Bioavailabilitybasic_science1completed
NCT00529035
Ultra-Low Dose Interleukin-2 for Refractory Chronic Graft Versus Host Diseasetreatment1completed
NCT00003335
Umbilical Cord Blood Transplantation in Treating Patients With High-Risk Hematologic Cancertreatment2completed
NCT00284986
Safety and Efficacy of Prochymal® for the Salvage of Treatment-Refractory Acute GVHD Patientstreatment2completed
NCT02588339
Panobinostat (LBH589): Acute Graft Versus Host Disease (aGVHD) Preventionprevention2completed
NCT02194439
Bridging Pediatric and Adult Biomarkers in Graft-Versus-Host DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT01911039
Phase 1 Infused Donor T Regulatory Cells in Steroid Dependent/Refractory Chronic GVHDNo drug interventionstreatment1completed
NCT03771222
Prophylactic Donor Lymphocyte Infusion After Allo-PBSCT for Patients With Very High-risk Hematologic Malignanciestreatment2unknown_status
NCT01240525
Donor Lymphocyte Infusion After Stem Cell Transplant in Treating Patients With Haematological CancersNo drug interventionstreatment2unknown_status
NCT02055625
Mesenchymal Stem Cells as a Treatment for Oral Complications of Graft-versus-host Diseasetreatment1 / 2withdrawn
NCT00248430
Donor White Blood Cell Infusions and Interleukin-2 in Treating Patients Who Are Undergoing an Autologous Stem Cell Transplant for Relapsed Advanced Lymphoid Cancertreatment1 / 2completed
NCT00603330
Mesenchymal Stem Cell Infusion as Treatment for Steroid-Resistant Acute Graft Versus Host Disease (GVHD) or Poor Graft FunctionNo drug interventionstreatment2recruiting
NCT00410657
Alemtuzumab and Glucocorticoids in Treating Newly Diagnosed Acute Graft-Versus-Host Disease in Patients Who Have Undergone a Donor Stem Cell Transplantsupportive_care2completed
NCT00462657
Early Diagnosis of Aspergillosis in Patients at High Risk of Fungal Infection Caused by Treatment for Hematologic Cancer or Other DiseaseNo drug interventionsdiagnosticNot Availableunknown_status
NCT00053157
Sargramostim in Reducing Graft-Versus-Host Disease in Patients Who Are Undergoing Donor Stem Cell Transplantation for Hematologic Cancer or Aplastic Anemiasupportive_careNot Availablecompleted
NCT04886726
PTCY Plus uhCG/EGF for Graft Versus Host Disease ProphylaxisNo drug interventionsprevention1recruiting
NCT00513474
Rasburicase in Preventing Graft-Versus-Host Disease in Patients With Hematologic Cancer or Other Disease Undergoing Donor Stem Cell Transplantsupportive_care1completed
NCT02561520
Safety and Efficacy of Autologous PRP and PPP Eye Drops in the Treatment of Ocular GVHDtreatment1withdrawn
NCT01927120
In Vivo Treg Expansion and Graft-Versus-Host Disease Prophylaxisprevention2completed
NCT02511782
Transdermal Patch to Monitor Inflammatory Biomarkers of GVHDNo drug interventionsotherNot Availablecompleted
NCT02877082
Tacrolimus, Bortezomib, & Thymoglobulin in Preventing Low Toxicity GVHD in Donor Blood Stem Cell Transplant Patientsprevention2terminated
NCT01428973
Minitransplants With HLA-matched Donors : Comparison Between 2 GVHD Prophylaxis Regimensprevention2active_not_recruiting
NCT01795573
Ex-vivo Expanded Donor Regulatory T Cells for Prevention of Acute Graft-Versus-Host DiseaseNo drug interventionsprevention1completed
NCT00948727
Cyclosporine Dose Adjustment According to Calcineurin Activity After Allogeneic Hematopoietic Stem-cell Transplantationprevention2completed
NCT05276076
A Prospective, Open Label, Dose-escalation, SAD/MAD, Multicenter, 24weeks, Phase I/IIa Clinical Trial to Evaluate the Safety, Tolerability and Pharmacodynamics of Investigational Product (VM-001) in Patients With Graft-versus-host Disease(GvHD)No drug interventionstreatment1 / 2not_yet_recruiting
NCT00053976
Methylprednisolone With or Without Daclizumab in Treating Patients With Acute Graft-Versus-Host Diseasetreatment3completed
NCT00972660
Safety and Efficacy Study of Allogenic Mesenchymal Stem Cells to Treat Extensive Chronic Graft Versus Host Diseasetreatment2unknown_status
NCT00004194
Fludarabine in Treating Patients With Steroid-Resistant Chronic Graft- Versus-Host Diseasesupportive_care1 / 2unknown_status
NCT01941394
Mesenchymal Stem Cells Infusion for aGVHD Prophylaxis TransplantationNo drug interventionsprevention2unknown_status
NCT00003894
Thalidomide in Treating Patients With Chronic Graft-Versus-Host Disease Following Bone Marrow Transplantsupportive_care2completed
NCT03367962
Detection of Graft Versus Host Disease With [18F]F-AraGNo drug interventionsdiagnostic1recruiting
NCT00003662
Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer or Other Hematologic or Metabolic Diseasestreatment2completed
NCT02193880
Safety of Post-transplant Alpha-beta Depleted T-cell Infusion Following Haploidentical Stem Cell Transplant (Haplo SCT)No drug interventionstreatmentNot Availablecompleted
NCT00001529
Improved Methods of Cell Selection for Bone Marrow Transplant AlternativesNot AvailableNot Availablerecruiting
NCT01633229
Bone Marrow Stromal Cell Infusions for Stem Cell Transplant ComplicationsNo drug interventionstreatment1completed
NCT05333029
Extracorporeal Photopheresis and Mesenchymal Stem Cell Infusion for GVHDtreatment2not_yet_recruiting
NCT02526329
Donor Regulatory T Cells in Treating Patients With Visceral Acute Graft-versus-Host Disease After Stem Cell TransplantNo drug interventionstreatment1withdrawn
NCT04290429
Treatment of Patients With Teduglutide (GLP-2) for GVHD and Analysis of Paneth Cells of GVHD Patientstreatment0completed
NCT01672229
Bortezomib in Patients With Chronic Graft Versus Host Diseasetreatment1completed
NCT00180089
Budesonide for Prevention of Acute Gastrointestinal GVHD Following Allogenic Stem Cell Transplantationprevention3completed
NCT00824889
Exploratory Study of Natural Killer Cells in Human SkinNo drug interventionsNot AvailableNot Availablecompleted
NCT00185692
Allogeneic Transplantation From Related Haploidentical Donorstreatment2completed
NCT01174940
Test Extracorporeal Photopheresis (ECP) Treatment Before/After Allogeneic Bone Marrow Transplant (BMT) or Peripheral Blood Stem Cell (PBSC) Transplant to Prevent Graft Versus Host DiseaseNo drug interventionstreatment0completed
NCT00054340
Combination Chemotherapy and Antithymocyte Globulin in Reducing Graft-Versus-Host Disease in Patients Undergoing Donor Stem Cell Transplantation For Myelodysplastic Syndrome or Myeloproliferative Disordersupportive_care1 / 2completed
NCT00755040
Cyclosporine Eye Drops in Preventing Graft-Versus-Host Disease of the Eye in Patients Who Have Undergone Donor Stem Cell Transplant for Hematologic Cancer or Bone Marrow Failure Disorderprevention3completed
NCT03459040
A Proof of Concept Pilot Trial of Alpha-1-Antitrypsin for Pre-Emption Of Steroid-Refractory Acute GVHDprevention2completed
NCT01453140
In-vivo Regulatory T Cell Enhancement With Cyclophosphamide and Sirolimustreatment1 / 2terminated
NCT00740467
Stem Cell Transplant in Treating Patients With Hematological Cancer or Other Disorderstreatment2unknown_status
NCT05289167
High-Dose Post-Transplant Cyclophosphamide, Bortezomib and Abatacept for the Prevention of Graft-versus-Host-Disease (GvHD) Following Allogenic Hematopoietic Stem Cell Transplantation (HSCT) Studytreatment1 / 2recruiting
NCT03263767
Post Transplant Cyclophosphamide (PTCY) as Sole Graft Versus Host Disease (GVHD) Prophylaxis for Matched Allotransplant: CYRICtreatment2terminated
NCT02144701
Lactobacillus Rhamnosus GG in Reducing Incidence of Graft-Versus-Host Disease in Patients Who Have Undergone Donor Stem Cell TransplantNo drug interventionssupportive_careNot Availablecompleted
NCT00813501
Immunologic Diagnostic Blood Test in Predicting Side-Effects in Patients Undergoing a Donor Stem Cell Transplant for Hematologic Cancer or Other DiseasesNo drug interventionsNot AvailableNot Availableterminated
NCT03924401
Acute GVHD Suppression Using Costimulation Blockade to Expand Non-malignant Transplantprevention2active_not_recruiting
NCT01988701
Lymphocyte Profiles and Activation Status in Patients With Graft-Versus-Host DiseaseNo drug interventionsNot AvailableNot Availablewithdrawn
NCT00004904
Stem Cell Transplantation in Treating Patients With Hematologic Cancertreatment1completed
NCT02195869
Study of the Bruton's Tyrosine Kinase Inhibitor in Subjects With Chronic Graft Versus Host Diseasetreatment1 / 2completed
NCT00792246
Voriconazole Pharmacokinetics in Children With Gastrointestinal Graft Versus Host Diseasetreatment1completed
NCT05655546
ImmunoCARE: Rapid, Accurate COVID Testing to Reduce Hospitalization of Immunocompromised IndividualsNo drug interventionsotherNot Availableactive_not_recruiting
NCT00826046
Prochymal® Expanded Access for Adults Who Have Failed Steroid Treatment for Acute Graft Versus Host Disease (GVHD)Not AvailableNot Availableno_longer_available
NCT00781781
Alemtuzumab Use (MabCampath®) in Hematopoietic Transplant of Unrelated Donor With Reduced Intensity Conditioningtreatment2terminated
NCT02080195
Nonmyeloablative Conditioning and Transplantation for Patients With Refractory Systemic Lupus Erythematosus (SLE)treatment1 / 2terminated
NCT00929695
Low-Dose Prednisone or Methylprednisolone in Treating Patients With Newly Diagnosed Acute Graft-versus-Host Diseasesupportive_care3completed
NCT00423514
Clofarabine, Melphalan, and Thiotepa Followed By a Donor Stem Cell Transplant in Treating Patients With High-Risk and/or Advanced Hematologic Cancer or Other Diseasetreatment1 / 2completed
NCT03880214
Prevalence of Chronic Oral Graft Versus Host Disease Risk Factors in Pediatric PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT01789255
Vorinostat, Tacrolimus, and Methotrexate in Preventing GVHD After Stem Cell Transplant in Patients With Hematological Malignanciessupportive_care2completed
NCT01485055
Infliximab and Basiliximab for Treatment of Steroid Refractory Acute Graft Versus Host Diseasetreatment2terminated
NCT00806208
Trial for Evaluation of Safety of Escalating Dose Levels of MEDI-507 in Patients for Treatment of at Least Grade II Graft-Versus-Host Disease (GvHD)treatment1completed
NCT05969743
Letermovir Prophylaxis for Cytomegalovirus (CMV) in Patients With Graft-versus-host Diseaseprevention2not_yet_recruiting
NCT01463475
University of Wisconsin hMSC Cell Bank: Bone Marrow Donor ProtocolNo drug interventionsNot AvailableNot Availablecompleted
NCT04167514
Treatment of GVHD in Hematopoietic Stem Cell Transplant (HSCT) Recipients Using AAT Plus Corticosteroids (CS) Compared With Corticosteroids Alone (BMT CTN 1705)treatment3active_not_recruiting
NCT02167451
Maraviroc as GVHD Prophylaxis in Transplant Recipientsprevention1 / 2terminated
NCT01324908
Biomarkers in Predicting Response in Patients With Graft-Versus-Host Disease Undergoing Extracorporeal PhotophoresisNo drug interventionstreatmentNot Availableterminated
NCT03680092
Comparing Cyclophosphamide and Abatacept With Standard of Care Treatment Following Stem Cell Transplantationtreatment2active_not_recruiting
NCT06590285
Diagnostic Refinement and Educational Approaches in Managing Bone Marrow TransplantationNo drug interventionssupportive_careNot Availablenot_yet_recruiting
NCT02156479
Clinical Validation of Lophius Biosciences Kit T-Track® CMV in Allo-HSCT RecipientsNo drug interventionsNot AvailableNot Availablecompleted
NCT02066051
IPL and Meibomian Gland Expression to Treat Ocular Rosacea Ocular GVHDNo drug interventionstreatmentNot Availablecompleted
NCT06469411
Effect of PMSCs and Their Secretome for the Treatment of GvHDNo drug interventionstreatment3completed
NCT02490163
Comparison of Two Automated Mononuclear Collection Systems in Patients Undergoing Extracorporeal Photochemotherapy. A Cross-over Equivalence Study. (MNC_CMNC)No drug interventionsNot Available3completed
NCT05544448
In Vitro Effect Study of Interleukin-2 Muteins on Regulatory T Cells of Patients With Different Autoimmune, Allo-immune or Inflammatory DiseasesNo drug interventionsbasic_scienceNot Availableunknown_status
NCT06462365
Prevention of GvHD in Participants With Hematological Malignancies Undergoing Hematopoietic Stem Cell Transplant (HSCT)No drug interventionsprevention1recruiting
NCT06000982
Comparison of Different Dose of Post-transplantation Cyclophosphamide as Graft Versus Host Disease ProphylaxisNo drug interventionsprevention3not_yet_recruiting
NCT06083129
Phase III Study Comparing GVHD Prophylaxis With ATG-thymoglobulin to ATLG-grafalon in Elderly Patients With Acute Myeloid Leukemia or Myelodysplasic Syndrome and Receiving an Allogeneic Hematopoietic Stem Cell Transplantation With a 10/10 HLA Matched Unrelated Donorprevention3not_yet_recruiting
NCT03851601
Immuno-regulatory Profiling of T Cells in GVHD Treated With Extracorporeal PhotopheresisNo drug interventionsNot AvailableNot Availablecompleted
NCT01295710
Study of US-ATG-F to Prevent Chronic Graft Versus Host Disease (GVHD)No drug interventionsprevention3completed
NCT06411184
Safety and Efficacy of Treg Cell in the Treatment of GVHDNo drug interventionstreatment1 / 2not_yet_recruiting
NCT04015947
Allogeneic Skin GraftingNo drug interventionsdevice_feasibilityNot Availablewithdrawn
NCT02338232
Study of TelmisartanFor the Prevention of Acute GVHD Post Allogeneic Hematopoietic Stem Cell TransplantationtreatmentNot Availableterminated
NCT03233659
Immune Monitoring After Allogeneic Hematopoietic Stem Cell TransplantationNo drug interventionsNot AvailableNot Availablecompleted
NCT02441075
70% Ethanol for Decontamination of CVL Exposed to Calcineurine Inhibitors Version 1.0, 1/9/2014No drug interventionstreatmentNot Availablecompleted
NCT03763318
A Study to Evaluate the Safety, Tolerability, PK, PD, and Clinical Activity of EQ001 in Subjects With aGVHDtreatment1 / 2completed
NCT04945096
Outcomes of Patients After Allo-HSCT With Decitabine and NACtreatment3not_yet_recruiting
NCT06075225
MAP-guided Preemptive Therapy of aGvHD by Ruxolitinibprevention2not_yet_recruiting
NCT05094765
Fecal Microbiota Transplant (FMT) Capsule for Improving the Efficacy of GI-aGVHDNo drug interventionstreatment0unknown_status
NCT03945591
High-Dose Post-Transplant Cyclophosphamide and Bortezomib (CyBor) for the Prevention of Graft-versus-Host Disease Following Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)treatment2completed
NCT02712762
Ocular Surface Disease in Chronic Graft-Versus-Host Disease (GVHD) PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT06334367
Prophylaxis of Graft-versus-host Disease With Anti-CD25 Antibody in Patients Underwent HSCTNo drug interventionsprevention2not_yet_recruiting
NCT03188601
α1-antitrypsin (AAT) Levels and Functions in Allogeneic Bone Marrow Transplantation and Throughout Progression Into GVHDNo drug interventionsNot AvailableNot Availablecompleted
NCT05415410
Proof-of-concept Trial of Apraglutide in GVHDtreatment2active_not_recruiting
NCT00447460
Treatment of Refractory (Acute or Chronic) Graft-Versus-Host Disease by the Infusion of Expanded in-Vitro Allogenic Mesenchymal Stem CellNo drug interventionstreatment1 / 2unknown_status