Acute Lymphocytic Leukemia (ALL) (DBCOND0030518)

Identifiers

Synonyms
Lymphoid Leukemia, Acute / Acute Lymphatic Leukemia / Acute Lymphoid Leukemia (ALL) / Acute Lymphocytic Leukemia / Acute Lymphocytic Leukaemia / Acute Lymphoid Leukemia / Acute Leukemia Lymphoid / Acute Leukemia, Lymphocytic / Acute Leukemia, Lymphoid / Acute lymphoblastic leukemia not having achieved remission / Acute lymphoblastic leukemia [ALL] / Acute lymphoblastic leukaemia / Leukemia lymphoblastic acute / Acute lymphoblastic leukemia / Lymphoid leukaemia, acute / Acute lymphoid leukaemia / Acute lymphoid leukemia, disease (disorder) / Leukaemia lymphoblastic acute / Acute lymphatic leukaemia / Leukaemias acute lymphocytic / Precursor cell lymphoblastic leukemia (morphologic abnormality) / Precursor Cell Lymphoblastic Leukemia-Lymphoma / Leukemia, Lymphocytic, Acute, L2

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Cytarabine
A pyrimidine nucleoside analogue used to treat acute non-lymphocytic leukemia, lymphocytic leukemia, and the blast phase of chronic myelocytic leukemia.
Mitoxantrone
A chemotherapeutic agent used for the treatment of secondary progressive, progressive relapsing, or worsening relapsing-remitting multiple sclerosis.
Vincristine
A vinca alkaloid used to treat acute leukemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis.
Vindesine
A vinca alkaloid derived from vinblastine used for various types of malignancies, but mainly acute lymphocytic leukemia (ALL).
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT05350163
T-cell Receptor α/β Depleted Donor Lymphocyte InfusionNo drug interventionstreatment1active_not_recruiting
NCT01111396
Longitudinal Investigation of Hippocampal Function and Morphology in Acute Lymphatic Leukemia (ALL) Patients Treated With ChemotherapyNo drug interventionsNot AvailableNot Availableunknown_status
NCT06508775
Long-Term Follow-up of Patients Treated With Miltenyi Cell and Gene TherapiesotherNot Availablerecruiting
NCT05250869
Comparative Quantification of MTX and Its Metabolites Post GlucarpidaseNo drug interventionsNot AvailableNot Availablecompleted
NCT00313053
Study of mAb 216 With Chemotherapy for Treatment of Pediatric Relapsed or Refractory B-progenitor Acute Lymphoblastic Leukemiatreatment1terminated
NCT03615105
Donor Stem Cell Transplantation Using α/β+ T-lymphocyte Depleted Grafts From HLA Mismatched Donorstreatment2terminated
NCT04872595
A Modified Dose of Rabbit Anti-thymocyte Globulin (rATG) in Children and Adults Receiving Treatment to Help Prepare Their Bodies for a Bone Marrow Transplanttreatment2active_not_recruiting
NCT00185523
Allogeneic Transplantation for Patients With Acute Leukemia or Chronic Myelogenous Leukemia (CML)No drug interventionsNot AvailableNot Availableterminated
NCT01768845
Unrelated Umbilical Cord Blood (UBC)TransplantationNo drug interventionstreatmentNot Availablecompleted
NCT02071927
Study of the Glutaminase Inhibitor CB-839 in Leukemiatreatment1completed
NCT03592576
Expanded Access to NavitoclaxNot AvailableNot Availableno_longer_available
NCT00664677
Phase 1 Study of Terameprocol (EM-1421) in Patients With Leukemiatreatment1terminated
NCT01962636
Umbilical Cord Blood Transplantation Using a Myeloablative Preparative Regimen for Hematological DiseasestreatmentNot Availablerecruiting
NCT00566696
Mismatched Family Member Donor Transplantation for Children and Young Adults With High Risk Hematological Malignanciestreatment2completed
NCT02086773
Red Cell Transfusion Goals in Patients With Acute LeukemiasNo drug interventionssupportive_care1completed
NCT03291444
CAR-T Cells Combined With Peptide Specific Dendritic Cell in Relapsed/Refractory Leukemia/MDSNo drug interventionstreatment1recruiting
NCT00923910
Wilm's Tumor 1 Protein Vaccine to Treat Cancers of the Bloodtreatment1 / 2completed
NCT00186823
Haploidentical Stem Cell Transplantation for Patients With Hematologic MalignanciesNo drug interventionstreatment3completed
NCT00088543
Thymoglobulin to Prevent Acute Graft vs. Host Disease (GvHD) in Patients With Acute Lymphocytic Leukemia (ALL) or Acute Myelogenous Leukemia (AML) Receiving a Stem Cell TransplantNot AvailableNot Availablecompleted
NCT03448393
CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory CD19/CD22-expressing B Cell Malignanciestreatment1recruiting
NCT05442515
CD19/CD22 Bicistronic Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory CD19/CD22-expressing B Cell Malignanciestreatment1 / 2recruiting
NCT05923112
BESPONSA Injection 1 mg Special InvestigationNo drug interventionsNot AvailableNot Availablecompleted
NCT04988555
A Study of DSP-5336 in Relapsed/refractory AML/ ALL with or Without MLL Rearrangement or NPM1 Mutationtreatment1 / 2recruiting
NCT06131801
Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a SolutionNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT06476665
A Study to Learn About the Safety of BESPONSA Injection in Pediatric Patients With Acute Lymphocytic Leukemia.No drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT01430390
In Vitro Expanded Allogeneic Epstein-Barr Virus Specific Cytotoxic T-Lymphocytes (EBV-CTLs) Genetically Targeted to the CD19 Antigen in B-cell Malignanciestreatment1active_not_recruiting
NCT03544021
CART-19 FOR Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL)treatment1 / 2unknown_status
NCT01338987
Pilot Study of Leuprolide to Improve Immune Function After Allogeneic Bone Marrow Transplantationtreatment2completed
NCT02043587
Chemotherapy With Liposomal Cytarabine CNS Prophylaxis for Adult Acute Lymphoblastic Leukemia & Lymphoblastic Lymphomatreatment2terminated
NCT00990587
Study Evaluating the Tolerance and Biologic Activity of Oral Ciclopirox Olamine in Patients With Relapsed or Refractory Hematologic Malignancytreatment1completed
NCT03110354
DS-3201b for Acute Myelogenous Leukemia (AML) or Acute Lymphocytic Leukemia (ALL)No drug interventionstreatment1terminated
NCT00352677
Safety and Tolerability Study of INNO-406 to Treat Chronic Myeloid Leukemia or Acute Lymphocytic Leukemiatreatment1completed
NCT05456698
Efficacy and Safety of Inotuzumab Ozogamicin in Treating Adult Patients With Ph Negative ALL With Minimal Residual Disease Positive After Induction Chemotherapytreatment2not_yet_recruiting
NCT05292898
A Triple-targeted Cell Preparation Targeting CD19/CD20/CD22 in Patients With Relapsed/Refractory B-cell Acute Lymphocytic LeukemiaNo drug interventionstreatment1active_not_recruiting
NCT05805605
Allo HSCT Using RIC and PTCy for Hematological Diseasestreatment2recruiting
NCT02765997
StemRegenin-1 Expanded vs Unexpanded UCB for High Risk Heme MalignanciesNo drug interventionstreatment2withdrawn
NCT00038883
Campath-1H and Allogeneic Blood Stem Cell Transplantation for Lymphoid MalignanciestreatmentNot Availableterminated
NCT05727683
CD19-targeted CAR T Cells for Patients With Relapsed or Refractory in B-cell Acute Lymphoblastic Leukemiatreatment1recruiting
NCT01500161
Pooled Unrelated Donor Umbilical Cord Blood Transplant For Hematologic Malignancy Needing Allogeneic Stem Cell Transplant Without Related HLA-Matchtreatment2terminated
NCT02141828
A Phase 1 Dose Escalation and Expanded Cohort Study of EPZ-5676 in the Treatment of Pediatric Patients With Relapsed/Refractory Leukemias Bearing a Rearrangement of the MLL Genetreatment1completed
NCT01965171
Transfusional Iron Overload Among Leukemia SurvivorsNo drug interventionsNot AvailableNot Availablecompleted
NCT01597778
Double Cord Versus Haploidentical (BMT CTN 1101)No drug interventionstreatment3completed
NCT00852709
Phase I Dose-Escalation Trial of Clofarabine Followed by Escalating Doses of Fractionated Cyclophosphamide in Children With Relapsed or Refractory Acute Leukemiastreatment1terminated
NCT01037556
PR104 in Treating Patients With Refractory/Relapsed Acute LeukemiaNo drug interventionstreatment1 / 2unknown_status
NCT01078337
T-cell Minimal Residual Disease (MRD) Evaluation Using Flow Cytometric AnalysisNo drug interventionsNot AvailableNot Availablecompleted
NCT03696537
IMRT-TMI With Fludarabine as Myeloablative Conditioning for Allogeneic HSCTtreatment1terminated
NCT03076437
Anti-CD19 Chimeric Antigen Receptor (CAR)-Transduced T Cell Therapy for Patients With B Cell MalignanciesNo drug interventionstreatment1 / 2completed
NCT02670252
BuCY vs TBICY Conditioning Regimen for Standard-risk ALL Undergoing Allo-HSCTtreatment3completed
NCT05021159
Assessing the Ontogeny of P-glycoprotein Expression in Blood of Pediatric Leukemic PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT04796675
Cord Blood Derived Anti-CD19 CAR-Engineered NK Cells for B Lymphoid Malignanciestreatment1unknown_status
NCT00975975
Basiliximab #2: In-Vivo Activated T-Cell Depletion to Prevent Graft-Versus_Host Disease (GVHD) After Nonmyeloablative Allotransplantation for the Treatment of Blood Cancertreatment2completed
NCT00309842
Myeloablative Umbilical Cord Blood Transplantation in Hematological Diseasestreatment2completed
NCT05775406
Safety and Clinical Activity of KT-253 in Adult Patients With High Grade Myeloid Malignancies, Acute Lymphocytic Leukemia, Lymphoma, Solid Tumorstreatment1recruiting
NCT00149136
Treatment of Philadelphia-Positive Acute Lymphocytic Leukemia (Ph+ ALL) in the Elderly With Imatinib Mesylate (STI571) and Chemotherapy.Not Available2unknown_status
NCT01745913
Randomized HaploCord Blood Transplantation vs. Double Umbilical Cord Blood Transplantation for Hematologic Malignanciestreatment2terminated
NCT01272817
Nonmyeloablative Allogeneic TransplantNo drug interventionstreatmentNot Availablecompleted
NCT00907517
Study of SCH 900776 (MK-8776) With and Without Cytarabine in Participants With Acute Leukemias (P05247)treatment1terminated
NCT01634217
Inducible Regulatory T Cells (iTregs) in Non-Myeloablative Sibling Donor Peripheral Blood Stem Cell TransplantationNo drug interventionstreatment1completed
NCT00905034
Methotrexate, Vincristine, Pegylated L-Asparaginase and Dexamethasone (MOAD) in Acute Lymphoblastic Leukemia (ALL) Salvagetreatment2completed
NCT05326516
A Study of Revumenib in Combination With Chemotherapy in Participants With R/R Acute Leukemiatreatment1completed
NCT00349596
A Study of Low-Dose Decitabine in Relapsed or Refractory Acute Lymphocytic Leukemia (ALL)treatment1completed
NCT01491958
Safety & Efficacy of Atorvastatin for Prophylaxis of Acute Graft Versus Host Disease in Patients With Hematological Malignancies HLA- Donor Hematopoietic Stem Cell Transplantationsupportive_care2completed
NCT02661035
Allo HSCT Using RIC for Hematological Diseasestreatment2completed
NCT00763763
Imatinib Mesylate With Vincristine and Dexamethasone in Acute Lymphoblastic Leukemias With BCR-ABL Positivetreatment2completed
NCT00271063
Study of Liposomal Annamycin in Patients With Refractory or Relapsed Acute Lymphocytic Leukemiatreatment1 / 2unknown_status
NCT01890486
The Prospective Collection, Storage and Reporting of Data on Patients Undergoing Hematopoietic Stem Cell Transplantation Utilizing a Standard Preparative RegimenNo drug interventionsNot AvailableNot Availablerecruiting
NCT05044039
Duvelisib Following Chimeric Antigen Receptor T-Cell Therapytreatment1recruiting
NCT03056339
Umbilical & Cord Blood (CB) Derived CAR-Engineered NK Cells for B Lymphoid Malignanciestreatment1 / 2completed
NCT00176839
Stem Cell Transplantation for Hematological Malignanciestreatment2 / 3terminated
NCT00176930
Stem Cell Transplant for Hematological MalignancytreatmentNot Availableterminated
NCT04629430
Effects of Prebiotics on Gut Microbiome in Patients Undergoing HSCTNo drug interventionstreatmentNot Availablecompleted
NCT00145626
HLA-Nonidentical Stem Cell and Natural Killer Cell Transplantation for Children Less the Two Years of Age With Hematologic Malignanciestreatment2completed
NCT03066466
Randomized Study: Standard of Care With or Without Atorvastatin for Prevention of GVHD for Matched Unrelated Donor BMTprevention3withdrawn
NCT01167166
Safety and Efficacy of 72-hour and 120-hour Infusion of Rigosertib in Acute Myeloid Leukemia (AML) and Acute Lymphoid Leukemia (ALL)treatment1 / 2completed
NCT05154474
Assessment of Sarcopenia at Diagnosis for Patients With Previously Untreated Metastatic Cancer or Hematologic MalignancyNo drug interventionsNot AvailableNot Availableunknown_status
NCT01853631
Activated T-Cells Expressing 2nd or 3rd Generation CD19-Specific CAR, Advanced B-Cell NHL, ALL, and CLL (SAGAN)No drug interventionstreatment1recruiting
NCT00548431
NOPHO ALL-2008 Pilot Study on Consolidation Therapy for Children and Adolescents With Acute Lymphoblastic Leukemiatreatment2completed
NCT01162031
Phase II Study of VELCADE for Relapsed or Refractory T-cell Prolymphocytic Leukemiatreatment2withdrawn
NCT03191773
A Study of Anti-CD19 CAR-T Cell Immunotherapy for Refractory /Relapsed B Cell MalignanciesNo drug interventionstreatment1 / 2unknown_status
NCT00586391
CD19 Chimeric Receptor Expressing T Lymphocytes In B-Cell Non Hodgkin's Lymphoma, ALL & CLLtreatment1active_not_recruiting
NCT01572662
Allogeneic Transplantation Using Timed Sequential Busulfan and Fludarabine Conditioningtreatment2completed
NCT00176462
CINJALL: Treatment for Children With Acute Lymphocytic Leukemiatreatment2completed
NCT00393380
Study of Parathyroid Hormone Following Sequential Cord Blood Transplantation From an Unrelated Donorprevention2terminated
NCT00001689
A Pharmacokinetic and Pharmacodynamic Study of Vincristine in Children With Leukemiatreatment1completed
NCT02851589
Study Evaluating the Efficacy and Safety of PCAR-019 in CD19 Positive Relapsed or Refractory Leukemia and LymphomaNo drug interventionstreatment1 / 2unknown_status
NCT00701844
Sharing Our Strength: A Research Study for Bone Marrow/Stem Cell Transplant SurvivorsNo drug interventionstreatmentNot Availablecompleted
NCT00155844
Studies on the Significance of CXCR4-CXCL12 on Leukemic Cells Passing Through"Marrow-Blood Barrier"No drug interventionsNot AvailableNot Availableunknown_status
NCT00167167
Donor Lymphocyte Infusion (DLI) for Relapsed (Post Transplant) LeukemiaNo drug interventionstreatmentNot Availablecompleted
NCT01163201
T-Regulatory Cell and CD3 Depleted Double Umbilical Cord Blood Transplantation in Hematologic Malignanciestreatment1 / 2withdrawn
NCT04771572
Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.No drug interventionstreatment1recruiting
NCT04940468
High- Fiber/ Low-fat Diet for Prevention of Recurrent Clostridioides Difficile Infection in OncologyNo drug interventionspreventionNot Availablerecruiting
NCT00251368
Multicenter Study of 9-Aminocamptothecin (9-AC) in Patients With Refractory Leukemiatreatment1completed
NCT01310946
Establishment of Acute Lymphocytic Leukemia Data Base in the Department of OncologyNo drug interventionsNot AvailableNot Availableunknown_status
NCT02315612
Anti-CD22 Chimeric Receptor T Cells in Pediatric and Young Adults With Recurrent or Refractory CD22-expressing B Cell MalignanciesNo drug interventionstreatment1active_not_recruiting
NCT05811910
Genetic Polymorphisms in Drug Induced Neuropathy in Children With ALLNo drug interventionsNot AvailableNot Availablerecruiting
NCT00061581
Experimental Bone Marrow Transplant ProtocolNo drug interventionstreatment2completed
NCT00963495
Study Evaluating the Tolerance and Biological Activity of Oral Clioquinol in Patients With Relapsed or Refractory Hematological Malignancytreatment1terminated
NCT03755414
Study of Itacitinib for the Prophylaxis of Graft-Versus-Host Disease and Cytokine Release Syndrome After T-cell Replete Haploidentical Peripheral Blood Hematopoietic Cell Transplantationtreatment1completed
NCT01586455
Human Placental-Derived Stem Cell TransplantationNo drug interventionstreatment1completed
NCT04803123
Window Trial to Evaluate Molecular Response to PI3K Inhibition With Copanlisib in r/r Adult B-cell ALLtreatment0terminated
NCT00594308
In-Vivo Activated T-Cell Depletion to Prevent GVHDtreatmentNot Availableterminated
NCT01551043
Allo CART-19 Protocoltreatment1terminated
NCT00067002
Randomized Double Cord Blood Transplant Studytreatment2completed
NCT00697684
Reduced Intensity Conditioning With Clofarabine, Antithymocyte Globulin (ATG), Total Lymphoid Irradiation (TLI) Followed by Allogeneic Stem Cell Transplanttreatment1completed
NCT00526084
Functional Pharmacogenomics of Childhood Acute Lymphoblastic Leukemia in TaiwanNo drug interventionsNot AvailableNot Availableunknown_status
NCT00674479
INCB018424 in Patients With Advanced Hematologic Malignanciestreatment2completed
NCT00313079
Monoclonal Antibody (mAb) 216 With Chemotherapy in Adult Relapsed or Refractory B-Lineage Acute Lymphoblastic Leukemiatreatment1completed
NCT02374333
Pilot Study of Redirected Autologous T Cells Engineered to Contain Humanized Anti-CD19 in Patients With Relapsed or Refractory CD19+ Leukemia and Lymphoma Previously Treated With Cell TherapyNo drug interventionstreatment1completed
NCT00098033
Investigation of Clofarabine in Acute Leukemiastreatment2completed
NCT02750254
Azacitidine in Haploidentical Donor Hematopoietic Cell Transplantationtreatment1terminated
NCT00968253
RAD001 Study in Treatment of Relapsed or Refractory Acute Lymphocytic Leukemiatreatment1 / 2completed
NCT02914977
Low-Dose Daunorubicin in Relapsed/Refractory Acute Leukemiatreatment1completed
NCT01350245
Bone Marrow Transplantation of Patients in Remission Using Partially Matched Relative Donortreatment2completed
NCT05565105
CD34+ Transplants for Leukemia and Lymphomatreatment2not_yet_recruiting
NCT01363297
Study Evaluating Inotuzumab Ozogamicin In Acute Lymphocytic Leukemiatreatment2completed
NCT05201183
A Dose Escalation Study of Intensity Modulated Total Marrow Irradiation (IMRT-TMI) Followed by Fludarabine as a Myeloablative Conditioning Regimen for Allogeneic Hematopoietic Stem Cell Transplantation for Patients With Relapsed and Refractory Hematologic Malignanciestreatment1 / 2withdrawn
NCT02819583
CAR-T Cell Immunotherapy in CD19 Positive Relapsed or Refractory Leukemia and LymphomaNo drug interventionstreatment1 / 2unknown_status
NCT00467961
Stem Cell Transplantation for Patients With Cancers of the BloodNo drug interventionstreatment2completed
NCT05170828
Cryopreserved MMUD BM With PTCy for Hematologic Malignanciestreatment1withdrawn
NCT03674411
Trial Evaluating MGTA-456 in Patients With High-Risk Malignancytreatment2active_not_recruiting
NCT00406393
Sirolimus/Tacrolimus Versus Tacrolimus/Methotrexate for Preventing Graft-Versus-Host Disease (GVHD) (BMT CTN 0402)treatment3completed
NCT02581007
Reduced Intensity Conditioning Transplant Using Haploidentical Donorstreatment2completed
NCT03088709
Haploidentical Stem Cell Transplantation Using Post-Transplant Cyclophosphamideprevention2terminated
NCT03263637
Study to Assess Safety, Tolerability, Pharmacokinetics and Antitumor Activity of AZD4573 in Relapsed/Refractory Haematological Malignanciestreatment1completed
NCT04004637
CD7 CAR-T Cells for Patients With R/R CD7+ NK/T Cell Lymphoma,T-lymphoblastic Lymphoma and Acute Lymphocytic LeukemiaNo drug interventionstreatment1unknown_status
NCT00483132
Study of Treatment High Risk and/or Low Risk Acute Lymphoblastic leukémia(ALL) Adults Stage IIItreatment3completed
NCT00516152
Phase II Study Evaluating Busulfan and Fludarabine as Preparative Therapy in Adults With Hematopoietic Disorders Undergoing MUD SCTtreatment2completed
NCT02410252
Use Feasibility of the iThermonitor in Pediatrics Patients on Myelosuppresive TherapiesNo drug interventionsotherNot Availablecompleted
NCT00773149
Alemtuzumab (CAMPATH 1H) Associated to G-CSF in Adult Patients With Refractory Acute Lymphocytic Leukemiatreatment1 / 2completed
NCT01049113
Safety Study of ON 013105 in Lymphoma and Acute Lymphoid Leukemiatreatment1terminated
NCT05410041
Anti-CD19 CAR-Engineered NK Cells in the Treatment of Relapsed/Refractory B-cell MalignanciesNo drug interventionstreatment1unknown_status
NCT03840317
Senl_1904A and Senl_1904B Chimeric Antigen Receptor (CAR) T-Cell in the Treatment of r/ r Acute B Lymphocytic LeukemiaNo drug interventionstreatment1unknown_status
NCT00089596
Infusion of Specially Treated Umbilical Cord Stem Cells After Chemoradiation Treatment for Blood CancersNo drug interventionstreatment1 / 2completed
NCT01100658
Effects of Methylphenidate on Attention Deficits in Childhood Cancer SurvivorstreatmentNot Availableterminated
NCT06481735
TCR Reserved and Power3 Gene Knock-out Allogeneic CD19-targeting CAR-T Cell Therapy in r/r B-ALLtreatment1 / 2recruiting
NCT02007863
Umbilical Cord Blood (UCB) Transplantation in Pediatric Patients With High Risk Leukemia and MyelodysplasiatreatmentNot Availablecompleted
NCT01075425
Belinostat and Bortezomib in Treating Patients With Relapsed or Refractory Acute Leukemia or Myelodysplastic Syndrometreatment1completed
NCT00304720
Tacrolimus and MMF as Post Grafting Immunosuppression After Conditioning With Flu TBI for HLA Matched Family Donortreatment2unknown_status
NCT02129582
Targeted Marrow Irradiation, Fludarabine Phosphate, and Busulfan Before Donor Progenitor Cell Transplant in Treating Patients With Hematologic Malignanciestreatment1completed
NCT00412360
Single vs Double Umbilical Cord Blood Transplants in Children With High Risk Leukemia and Myelodysplasia (BMT CTN 0501)treatment3completed
NCT03104491
Inotuzumab Ozogamicin Post-Transplant For Acute Lymphocytic Leukemiatreatment1 / 2recruiting
NCT01930162
Safety and Tolerability of HSC835 in Patients With Hematological Malignancies Undergoing Single Umbilical Cord Blood Transplantbasic_science2completed
NCT00246662
Safety Assessment of Two Schedules of Intravenous Infusions of SNS-595 for the Treatment of Hematologic Malignanciestreatment1completed
NCT00571662
Safety and Efficacy of Pentostatin and Low Dose TBI With Allogenic Peripheral Blood Stem Cell Transplanttreatment2completed
NCT00167180
Post Transplant Donor Lymphocyte Infusiontreatment2terminated
NCT00005892
Study of Allogeneic Bone Marrow Transplantation Following Cyclophosphamide and Radiotherapy in Patients With Myelodysplastic Syndrome and Acute Leukemia Related to Fanconi's AnemiatreatmentNot Availablecompleted
NCT03934372
Safety and Efficacy of Ponatinib for Treatment of Pediatric Recurrent or Refractory Leukemias, Lymphomas or Solid Tumorstreatment1 / 2recruiting
NCT00854646
Phase I Study of ON 01910.Na in Refractory Leukemia or Myelodysplastic Syndrome (MDS)treatment1completed
NCT01050946
Hematopoietic Stem Cell Transplantation (HSCT) Using CD34 Selected Mismatched Related Donor and One Umbilical Cord UnitNo drug interventionstreatment2terminated
NCT01474681
Safety and Tolerability of HSC835 in Patients With Hematological Malignanciestreatment1 / 2completed
NCT01600781
Effect of Oral Supplementation With a Fibre Enriched Paediatric Sip Feed For Children With Acute Lymphocytic LeukemiaNo drug interventionssupportive_careNot Availablecompleted
NCT02892695
PCAR-119 Bridge Immunotherapy Prior to Stem Cell Transplant in Treating Patients With CD19 Positive Leukemia and Lymphomatreatment1 / 2unknown_status
NCT01702155
Phase I/II Study of DFP-10917 in Patients With Acute LeukemiaNo drug interventionstreatment1 / 2completed
NCT03633955
Pilot Imaging Study of LeukemiaNo drug interventionsdiagnostic1recruiting
NCT03555955
A Trial to Evaluate the Potential Impact of Renal Impairment on the Pharmacokinetics and Safety of CPX-351treatment1completed
NCT00537550
Adult ALL Treatment at DiagnosistreatmentNot Availablecompleted
NCT02456350
Anti-CD19 Chimeric Antigen Receptor (CAR)-Transduced T Cell Therapy for Patients With B Cell Malignanciestreatment1unknown_status
NCT02593123
Adoptive Immunotherapy in Relapsed Hematological Malignancy: Early GVHD Prophylaxistreatment2completed
NCT00430443
Liposomal Annamycin in Children and Young Adults With Refractory or Relapsed ALL or AMLtreatment1terminated
NCT00475384
Haploidentical Transplantation in Patients With Acute Leukemia and Myelodysplasiatreatment1completed
NCT05086315
First-in-human Study of SAR443579 Infusion in Male and Female Children and Adult Participants With Relapsed or Refractory Acute Myeloid Leukemia (R/R AML), B-cell Acute Lymphoblastic Leukemia (B-ALL), High Risk-myelodysplasia (HR-MDS), or Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)No drug interventionstreatment1 / 2recruiting
NCT01440179
SAR3419 in Acute Lymphoblastic Leukemiatreatment2terminated
NCT03760237
Cardiovascular Function in Acute LeukemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT05322850
Phase I/II Trial: Engineered Donor Graft (Orca Q) for Pediatric Hematopoietic Cell Transplant (HCT)No drug interventionstreatment1 / 2suspended
NCT05535855
UCD19 CAR T Therapy in Adults with B-ALL and MRD Positivity in CR1No drug interventionstreatment1recruiting
NCT05827549
Evaluation of Treatment Efficacy According to Risk Group in Relapsed Childhood Acute Lymphoblastic Leukemiahealth_services_research2recruiting
NCT03977103
Irradiation-based Myeloablative Conditioning Followed by Treg/Tcon Immunotherapy in HSCTNo drug interventionstreatment2unknown_status
NCT01720264
Multicenter Phase II of CD26 Using Sitagliptin for Engraftment After UBC Transplanttreatment2completed
NCT01037764
Donor-specific Allogeneic Hematopoietic Cell Transplantation for Acute Lymphoblastic Leukemia (ALL)No drug interventionstreatment2terminated
NCT02413021
The Effect of Deferasirox on Response Rate of Acute Leukemia Patients Not Treated by Standard Chemotherapy Regimenstreatment1unknown_status
NCT04778579
Study of the Infusion of ARI-0001 Cells in Patients With CD19 + Acute Lymphoid Leukemia Resistant or Refractory to Therapytreatment2active_not_recruiting
NCT04167683
Muscle Dysfunction in Patients With Hematological Diseases Referred to Stem Cell TransplantNo drug interventionsNot AvailableNot Availablerecruiting
NCT01749111
Comparison Between Cyclophosphamide and Combination of Methotrexate + Calcineurin Inhibitor for GVHD Prophylaxisprevention3terminated
NCT02767388
Electrophysiological Biomarkers of Chemotherapy-related Cognitive Impairment and RecoveryNo drug interventionsNot AvailableNot Availablecompleted
NCT02294552
Post-transplantation Cyclophosphamide as GVHD Prophylaxis After HSCTtreatment2completed
NCT05166135
Latin American Real-world Study in Acute LeukemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT02458235
Donor Lymphocyte Infusion With Azacitidine to Prevent Hematologic Malignancy Relapse After Stem Cell Transplantationtreatment2completed
NCT02953730
The Study on the Pharmacokinetics of PEG-rhG-CSF in Children and AdolescentsNo drug interventionstreatment4completed
NCT06427330
Phase II Study of Post-Transplant Low-Dose Inotuzumab Ozogamicin to Prevent Relapse of Acute Lymphoblastic Leukemiaprevention2recruiting
NCT05587088
Evaluation of the Safety and Efficacy of Esperanza Extract (PA001)No drug interventionstreatment1 / 2not_yet_recruiting
NCT05959720
Adult Acute Lymphoblastic Leukemia Treated With Pediatric Regimen in BrazilNot AvailableNot Availablerecruiting
NCT01344876
Phase I Study of OPB-51602 in Patients With Hematologic MalignanciesNo drug interventionstreatment1completed
NCT02605460
Chemo Sensitization Before Hematopoietic Stem Cell Transplantation in Patients With Acute Leukemia in Complete Remissiontreatment2unknown_status
NCT03833180
A Study of Zilovertamab Vedotin (MK-2140) (VLS-101) in Participants With Hematologic Malignancies (MK-2140-001)treatment1completed
NCT05316701
Precision-T: A Randomized Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic MalignanciesNo drug interventionstreatment3active_not_recruiting
NCT04669210
PTCy and Ruxolitinib vs PTCy, Tacrolimus and MMF in MUD and Haploidentical HSCTprevention2active_not_recruiting
NCT02435550
iCare for Cancer PatientsNo drug interventionsdiagnosticNot Availableterminated
NCT00983138
Efficacy and Safety of Recombinant Asparaginase in Infants With Previously Untreated Acute Lymphoid Leukemia (ALL)treatment2completed
NCT06551584
Phase I Trial for Patients w/ Advanced Hematologic Malignancies Undergoing Allogeneic HCTtreatment1not_yet_recruiting
NCT02933333
G-CSF Alone or Combination With GM-CSF on Prevention and Treatment of Infection in Children With Malignant Tumortreatment4unknown_status
NCT03792633
Study of huCART19 for Very High-Risk (VHR) Subsets of Pediatric B-ALLNo drug interventionstreatment2active_not_recruiting
NCT05150561
Muscle Dysfunction in Patients With Haematological DiseasesNo drug interventionsNot AvailableNot Availableunknown_status
NCT05943093
H19 in Acute Lymphoblastic Leukemia.No drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT05792007
Study of the Medullary Microenvironment in Acute Childhood LeukemiaNo drug interventionsdiagnosticNot Availablerecruiting
NCT04013685
Precision-T: A Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic MalignanciesNo drug interventionstreatment1active_not_recruiting
NCT02345915
Evaluation of Adverse Long-term Effects in Young Adult Survivors of Acute LeukemiaNo drug interventionsbasic_scienceNot Availableunknown_status
NCT00590915
Erwinase Master Treatment ProtocolNot AvailableNot Availableno_longer_available
NCT03367299
Sequential Chemotherapy and Blinatumomab to Improve MRD Response and Survival in Acute Lymphoblastic Leukemiatreatment2unknown_status
NCT02523976
Dasatinib Combined With Chemotherapy in Philadelphia Chromosome-positive Acute Lymphoblastic Leukemiatreatment2completed
NCT04464889
HA-1H TCR T Cell for Relapsed/Persistent Hematologic Malignancies After Allogeneic Stem Cell TransplantationNo drug interventionstreatment1withdrawn
NCT02419755
Bortezomib and Vorinostat in Younger Patients With Refractory or Relapsed MLL Rearranged Hematologic Malignanciestreatment2terminated
NCT01461538
Brentuximab Vedotin in Patients With CD30-positive Nonlymphomatous Malignanciestreatment2completed
NCT03610438
Feasibility and Effectiveness of Inotuzumab Ozogamicin in B-Cell Acute Lymphoblastic Leukemiatreatment2unknown_status