Severe Alopecia Areata (AA)

Drug	Drug Name	Drug Description
DB14924	Ritlecitinib	A kinase inhibitor used to treat severe alopecia areata in adults and adolescents 12 years and older.

Drug	Drug Name	Target	Type
DB14924	Ritlecitinib	Tyrosine-protein kinase JAK3	target
DB14924	Ritlecitinib	Tyrosine-protein kinase Tec	target
DB14924	Ritlecitinib	Tyrosine-protein kinase ITK/TSK	target
DB14924	Ritlecitinib	Tyrosine-protein kinase TXK	target
DB14924	Ritlecitinib	Tyrosine-protein kinase BTK	target
DB14924	Ritlecitinib	Cytoplasmic tyrosine-protein kinase BMX	target
DB14924	Ritlecitinib	Cytochrome P450 3A4	enzyme
DB14924	Ritlecitinib	Cytochrome P450 2C8	enzyme
DB14924	Ritlecitinib	Cytochrome P450 1A2	enzyme
DB14924	Ritlecitinib	Cytochrome P450 2C9	enzyme
DB14924	Ritlecitinib	Glutathione S-transferase A1	enzyme
DB14924	Ritlecitinib	Glutathione S-transferase A3	enzyme
DB14924	Ritlecitinib	Glutathione S-transferase Mu 1	enzyme
DB14924	Ritlecitinib	Glutathione S-transferase Mu 3	enzyme
DB14924	Ritlecitinib	Glutathione S-transferase Mu 5	enzyme
DB14924	Ritlecitinib	Glutathione S-transferase P	enzyme
DB14924	Ritlecitinib	Glutathione S-transferase theta-2	enzyme
DB14924	Ritlecitinib	Maleylacetoacetate isomerase	enzyme
DB14924	Ritlecitinib	Microsomal glutathione S-transferase 1	enzyme
DB14924	Ritlecitinib	Microsomal glutathione S-transferase 2	enzyme
DB14924	Ritlecitinib	Microsomal glutathione S-transferase 3	enzyme

Drug	Drug Name	Phase	Status	Count