Heart Failure With Reduced Ejection Fraction (HFrEF)

Also known as: Hearth Failure With Reduced Ejection Fraction (HFrEF) / Heart Failure With Reduced Ejection Fraction / Reduced ejection fraction heart failure / Systolic Heart Failure / Heart Failure and Reduced Ejection Fraction / Heart Failure, Reduced Ejection Fraction / Heart Failure With Reduced Ejection Fraction (HF-rEF) / Heart Failure With Reduced Ejection Fraction, HFrEF / Heart Failure Systolic / Heart Failure, Systolic / Systolic heart failure (disorder) / Unspecified systolic (congestive) heart failure / Heart failure with reduced ejection fraction (disorder) / Left ventricular failure / Left ventricular failures / LVF / Left ventricular insufficiency / Failure heart left / Left heart failure / Cardiac asthma / Heart Failure, Left-Sided / Left heart failure (disorder) / (Left ventricular: [failure] or [impaired function]) or (cardiac asthma) or (acute pulmonary oedema) / Cardiac failure left / Left cardiac failure / Pulmonary oedema cardiac cause / Pulmonary edema cardiac cause / Failure left heart

DrugDrug NameDrug Description
DB00178RamiprilAn ACE inhibitor used for the management of hypertension and the reduction of cardiovascular mortality following myocardial infarction in hemodynamically stable patients with clinical signs of congestive heart failure.
DrugDrug NamePhaseStatusCount
DB14933Nicotinamide riboside0Recruiting1
DB16130Dapansutrile1Completed1
DB15726Human Umbilical Cord Mesenchymal Stem Cells1 / 2Not Yet Recruiting1
DB15039ITI-2141 / 2Completed1
DB00026Anakinra2Recruiting1
DB00026Anakinra2Withdrawn1
DB06292Dapagliflozin2Not Yet Recruiting1
DB09038Empagliflozin2Completed1
DB09303Evolocumab2Active Not Recruiting1
DB08917Ferric carboxymaltose2Completed1
DB15763Iron polymaltose2Completed1
DB01065Melatonin2Recruiting1
DB00331Metformin2Completed1
DB00627Niacin2Recruiting1
DB11062Octisalate2Withdrawn1
DB09535Octocrylene2Withdrawn1
DB11816Omecamtiv Mecarbil2Completed1
DB01032Probenecid2Completed1
DB01220Rifaximin2Recruiting1
DB00073Rituximab2Not Yet Recruiting1
DB09292Sacubitril2Completed1
DB09321Zinc oxide2Withdrawn1
DB13257Ferrous sulfate anhydrous2 / 3Completed1
DB06292Dapagliflozin3Completed1
DB00584Enalapril3Completed2
DB00584Enalapril3Terminated1
DB11827Ertugliflozin3Recruiting1
DB08917Ferric carboxymaltose3Recruiting1
DB11816Omecamtiv Mecarbil3Active Not Recruiting1
DB09292Sacubitril3Completed2
DB09292Sacubitril3Terminated1
DB14048Sodium zirconium cyclosilicate3Not Yet Recruiting1
DB00052Somatotropin3Completed1
DB06267Udenafil3Terminated1
DB08907Canagliflozin4Completed1
DB01136Carvedilol4Unknown Status1
DB00880Chlorothiazide4Terminated1
DB00758Clopidogrel4Completed1
DB06292Dapagliflozin4Active Not Recruiting1
DB06292Dapagliflozin4Not Yet Recruiting1
DB06292Dapagliflozin4Recruiting1
DB00584Enalapril4Completed2
DB00584Enalapril4Withdrawn1
DB00700Eplerenone4Enrolling by Invitation1
DB08917Ferric carboxymaltose4Not Yet Recruiting1
DB01592Iron4Recruiting1
DB09083Ivabradine4Recruiting1
DB00922Levosimendan4Not Yet Recruiting1
DB00922Levosimendan4Recruiting1
DB00451Levothyroxine4Unknown Status1
DB00722Lisinopril4Unknown Status1
DB00331Metformin4Unknown Status1
DB00524Metolazone4Terminated1
DB06209Prasugrel4Completed1
DB09292Sacubitril4Completed4
DB09292Sacubitril4Recruiting1
DB09292Sacubitril4Withdrawn1
DB01261Sitagliptin4Completed1
DB14048Sodium zirconium cyclosilicate4Recruiting1
DB00421Spironolactone4Enrolling by Invitation1
DB00177Valsartan4Completed3
DB00177Valsartan4Recruiting1
DB00177Valsartan4Withdrawn1
DB00661Verapamil4Unknown Status1
DB11842Angiotensin IINot AvailableActive Not Recruiting1
DB08822Azilsartan medoxomilNot AvailableActive Not Recruiting1
DB00612BisoprololNot AvailableActive Not Recruiting1
DB00612BisoprololNot AvailableRecruiting1
DB00188BortezomibNot AvailableCompleted1
DB13919CandesartanNot AvailableActive Not Recruiting1
DB00876EprosartanNot AvailableActive Not Recruiting1
DB08917Ferric carboxymaltoseNot AvailableActive Not Recruiting1
DB01029IrbesartanNot AvailableActive Not Recruiting1
DB15763Iron polymaltoseNot AvailableActive Not Recruiting1
DB09083IvabradineNot AvailableActive Not Recruiting1
DB09083IvabradineNot AvailableRecruiting1
DB00678LosartanNot AvailableActive Not Recruiting1
DB00264MetoprololNot AvailableRecruiting1
DB00275OlmesartanNot AvailableActive Not Recruiting1
DB09292SacubitrilNot AvailableActive Not Recruiting1
DB09292SacubitrilNot AvailableCompleted2
DB09292SacubitrilNot AvailableNo Longer Available1
DB09292SacubitrilNot AvailableRecruiting2
DB09292SacubitrilNot AvailableUnknown Status1
DB00966TelmisartanNot AvailableActive Not Recruiting1
DB00966TelmisartanNot AvailableRecruiting1
DB00177ValsartanNot AvailableActive Not Recruiting1
DB00177ValsartanNot AvailableCompleted1
DB00177ValsartanNot AvailableRecruiting2
DB00177ValsartanNot AvailableUnknown Status1