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Solute carrier organic anion transporter family member 4C1
go.drugbank.com/bio_entities/BE0003653TransporterTargetHumansCapable of transporting cAMP and pharmacological substances such as digoxin, ouabain and methotrexate (PubMed:14993604). Transport is independent of sodium, chloride ion, and ATP (PubMed:14993604). … The role of hydrogencarbonate (HCO3(-), bicarbonate) as the probable counteranion that exchanges for organic anions is still not well defined (PubMed:19129463).
Carbonic anhydrase
go.drugbank.com/bio_entities/BE0009965TargetEnzymeHumansMay stimulate the sodium/bicarbonate transporter activity of SLC4A4 that acts in pH homeostasis (PubMed:15563508). … Stimulates the chloride-bicarbonate exchange activity of SLC26A6 (PubMed:15990874). Essential for bone resorption and osteoclast differentiation (PubMed:15300855).
Osteoporosis
go.drugbank.com/conditions/DBCOND0015928Drugs: Abaloparatide · Alendronic acid · Boron · Calcium · Calcium carbonate · Calcium citrate +20 moreDevelop NSAID-induced gastric ulcers
go.drugbank.com/conditions/DBCOND0106145Dry Eyes
go.drugbank.com/conditions/DBCOND0054254Drugs: Acrylic Acid · Carbomer · Carbomer homopolymer type C · Carbopol 974P · Carboxymethylcellulose · Chamomile +12 moreOsteodystrophy
go.drugbank.com/conditions/DBCOND0016488Osteomalacia
go.drugbank.com/conditions/DBCOND0002028Drugs: Alfacalcidol · Calcium · Calcium carbonate · Calcium gluconate · Calcium lactate gluconate · Cholecalciferol +1 moreCalcium Deficiency
go.drugbank.com/conditions/DBCOND0052248Drugs: Calcium · Calcium Phosphate · Calcium carbonate · Calcium citrate · Calcium glubionate anhydrous · Calcium gluconate +4 moreDry Eye Syndrome (DES)
go.drugbank.com/conditions/DBCOND0074986Drugs: Benzalkonium · Carbomer · Diquafosol · Hydroxypropyl cellulose · Lifitegrast · Loteprednol etabonate +4 more