NCT02424266
Three Dimension Tomography of Eye Structures by White Light Imaging Device No drug interventions Not Available Not Available unknown_status NCT06189456
Evaluation of Performance and Safety of Eye Drops With Hyaluronic Acid 0.30% and 0.15% No drug interventions treatment Not Available recruiting NCT04140227
Long-Term Safety and Tolerability of NOV03 (Perfluorohexyloctane) in Subjects Who Completed Trial NVU-003 (Kalahari Study) treatment 3 completed NCT01998802
Phase 3 Study of EBI-005 in Dry Eye Disease No drug interventions treatment 3 completed NCT04139798
Perfluorohexylcotane (NOV03) for the Treatment of Signs and Symptoms of Dry Eye Disease Associated With Meibomian Gland Dysfunction (Gobi Study) No drug interventions treatment 3 completed NCT05723770
Effects of NOV03 on the Tear Film No drug interventions treatment 4 completed NCT04523142
CyclASol for the Treatment of Signs and Symptoms of Dry Eye Disease in Subjects Who Completed CYS-004 No drug interventions treatment 3 completed NCT06573606
Ophthalmic Solution in Diabetic Corneal Alteration No drug interventions Not Available Not Available completed NCT04393441
Efficacy and Safety of a New Artificial Tear Formulation Compared With Systane Ultra Multidose in Participants With Dry Eye Disease No drug interventions treatment 3 completed NCT03333057
Perfluorohexyloctane (NOV03) for the Treatment of Signs and Symptoms of Dry Eye Disease (DED) No drug interventions treatment 2 completed NCT04036292
Evaluation of the Efficacy and Safety of OC-01 Nasal Spray on Signs and Symptoms of Dry Eye Disease No drug interventions treatment 3 completed NCT03467490
Self-care Management Program for Dry Eye Disease Patients Using the heiQ No drug interventions supportive_care Not Available unknown_status NCT04530864
Pre-Surgical Ocular Surface Treatment With Intracanalicular Dexamethasone Insert And Effect On Intraocular Lens Measurement Accuracy No drug interventions treatment 4 unknown_status NCT05629364
A Multi-Centre, Randomised, Controlled, Masked Phase 2 Study of the Safety and Efficacy of KIO-101 Ophthalmic Solution, Versus Vehicle Control in the Treatment of Dry Eye Disease in Patients With Autoimmune Disease No drug interventions treatment 2 terminated NCT04477421
Femtosecond Small Incision Lenticular Extraction in Comparison to Femtosecond Laser Insitu Keratomileusis Regarding Dry Eye Disease No drug interventions treatment Not Available completed NCT01650584
Evaluation of Ocular Comfort With ISTA Tears vs Systane No drug interventions treatment Not Available completed NCT06208384
Topical Statin Eye Drop in the Management of the Dry Eye No drug interventions treatment 1 / 2 active_not_recruiting NCT06178679
Safety and Efficacy of ST-100 (Vezocolmitide) Ophthalmic Solution 60 μg/ml Ophthalmic Solution in Subjects Diagnosed With Dry Eye Disease (DED) No drug interventions treatment 3 recruiting NCT05857579
Diamond Bur Microblepharoexfoliation, Intense Pulse Light and Meibomian Gland Expression for Evaporative Dry Eye No drug interventions treatment Not Available completed NCT06375343
Study to Evaluating PRO-240 Ophthalmic Solution Compared to Optive® No drug interventions treatment 1 not_yet_recruiting NCT00407043
Multicenter, Randomized, Controlled Study of the Effect of Lotemax on Initiation of Dry Eye Treatment With Restasis No drug interventions treatment 4 completed NCT02831387
Evaluation of P-321 Ophthalmic Solution Compared to Placebo in Subjects With Dry Eye Disease No drug interventions treatment 2 terminated NCT05187533
Sphenopalatine Ganglion Stimulation for Ocular and Oral Dryness No drug interventions treatment Not Available recruiting NCT06443554
Evaluation of the Effectiveness of a Community Health Management Program for Dry Eye Disease in Middle-Aged and Elderly Individuals No drug interventions treatment Not Available recruiting NCT05604651
Comparison of Mucin Levels at the Ocular Surface of Visual Display Users With and Without Dry Eye Disease No drug interventions Not Available Not Available completed NCT05758753
QST for Corneal Nerve Function No drug interventions treatment Not Available enrolling_by_invitation NCT05487547
Feasibility of IPL Combined With RF for Treatment of DED Due to MGD No drug interventions treatment Not Available completed NCT06221345
Hyaluronic Acid-containing Artificial Tears in Post-cataract Surgery Dry Eye Disease treatment 4 completed NCT01421498
Safety and Efficacy Study of SAR 1118 to Treat Dry Eye Conducted in a Controlled Adverse Environment (CAE) (OPUS-1) treatment 3 completed NCT03452397
Clinical Trial to Evaluate the Efficacy of OC-02 Nasal Spray on Signs and Symptoms of Dry Eye Disease (The PEARL Study) treatment 2 completed NCT04084483
A Study Assessing the Safety, Efficacy, and Optimum Dosage of K-161 in Subjects With Moderate to Severe Dry Eye Disease No drug interventions treatment 2 completed NCT05553561
Intense Regulated Pulse Light Therapy in Dry Eye Disease No drug interventions treatment Not Available recruiting NCT03636061
Evaluation of the Efficacy of OC-01 Nasal Spray on Signs and Symptoms of Dry Eye Disease treatment 2 completed NCT04785261
Effect of Traditional Chinese Medicine on Basic Tear Secretion and Tear Cytokines in Patients With Dry Eye Disease treatment 2 unknown_status NCT02111928
NovaTears® Eye Drops Observational Study No drug interventions Not Available Not Available completed NCT05486728
Phase II Study of SHJ002 Sterile Ophthalmic Solution Compared With Vehicle in Participants With Dry Eye Disease No drug interventions treatment 2 completed NCT05848128
Efficacy and Safety Evaluation of Tavilermide Ophthalmic Solution for the Treatment of Dry Eye treatment 3 completed NCT06122428
Efficacy of Riboflavin-Enhanced Hyaluronic Acid Eye Drops in Treating Dry Eye Disease Not Available Not Available completed NCT05957211
Improving Drop Instillation Comfort of a Cyclosporine A Solution supportive_care Not Available completed NCT06018571
Burden of Illness and Treatment Assessment of Patients With Dry Eye Disease: A Cross-Sectional Survey of Real-World Patients With Dry Eye Disease in the US No drug interventions Not Available Not Available completed NCT00600288
Study of the Effect of Diquafosol Tetrasodium Ophthalmic Solution, 2% Versus Placebo in Dry Eye Subjects (P08634) treatment 3 completed NCT05372107
A Study of AG-80308 in Dry Eye Patients No drug interventions treatment 1 completed NCT06544707
A Study Designed to Evaluate Tear Production treatment 3 not_yet_recruiting NCT05213156
Concentration of Ofloxacin Into the Aqueous Humour of Patients With Dry Eye Disease No drug interventions screening 4 completed NCT06349356
Prospective Evaluation of Efficacy and Safety of an Intense Pulsed Light Device to Treat Dry Eye Disease" No drug interventions treatment Not Available active_not_recruiting NCT06370585
Clinical Study to Evaluate the Safety and Tolerability of PRO-229 Ophthalmic Solution Compared to Lagricel® Ofteno PF treatment 1 not_yet_recruiting NCT00403715
Study of INS365 Ophthalmic Solution in Subjects With Dry Eye Disease treatment 3 completed NCT05576415
Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of OC-01 in Adult Chinese With Dry Eye Disease treatment 1 completed NCT02242032
Study of the Safety and Tolerability of P 321 Ophthalmic Solution in Subjects With Dry Eye Disease No drug interventions treatment 1 completed NCT05825352
PMCF Study to Evaluate Performance and Safety of "Ocular Drops Based Upon Carmellose" Used to Relieve Dry Eye Symptoms No drug interventions treatment Not Available completed NCT05586152
Study of INV-102 Ophthalmic Solution in Adults With Moderate Symptomatic Dry Eye Disease No drug interventions treatment 1 / 2 completed NCT04235400
Multimodal Screening of Dry Eye Disease No drug interventions Not Available Not Available unknown_status NCT05824000
PMCF Study to Evaluate Performance and Safety of "Optrex Double Action Soothing and Lubricating Drops" No drug interventions treatment Not Available completed NCT06058559
Effect of Sunflower Lecithin Supplementation on Meibomian Gland Function in Adults With Dry Eye Disease No drug interventions other Not Available completed NCT00395759
The Visual Effect of an Investigational Artificial Tear in the Tear Layer. supportive_care Not Available completed NCT06400459
IVW-1001 Phase 1/2 in Subjects With Dry Eye Disease treatment 1 / 2 recruiting NCT03660475
Effect of Topical Naltrexone Ophthalmic Solution on the Signs and Symptoms of Dry Eye in Diabetic Subjects treatment 2 completed NCT00403975
Study of Diquafosol Tetrasodium Ophthalmic Solution in Subjects With Dry Eye Disease treatment 3 completed NCT05896670
Safety and Efficacy of Licaminlimab Ophthalmic Suspension for the Treatment of Dry Eye Disease treatment 2 active_not_recruiting NCT04362670
Study to Evaluate the Safety, Tolerability, and Efficacy of OTX-CSI in Subjects With Dry Eye Disease. No drug interventions treatment 1 / 2 completed NCT05168670
Safety of Tinted Soft Scleral Eye Shields When IPL is Applied on Eyelids No drug interventions treatment Not Available completed NCT05241470
Study of ST-100 as Treatment for Dry Eye Disease No drug interventions treatment 2 completed NCT04608942
Refractory Meibomian Gland Dysfunction and Plasma Jet No drug interventions treatment Not Available unknown_status NCT06162442
Management of the Ocular Surface With Preservative-Free Lubricants in Patients With Dry Eye Not Available Not Available recruiting NCT01636206
Safety Study of Lifitegrast to Treat Dry Eye treatment 3 completed NCT02824913
Study of the Pharmacodynamic Activity of P-321 Ophthalmic Solution Compared to Placebo in Subjects With Dry Eye Disease No drug interventions treatment 2 terminated NCT00679718
A Study of INS365 Ophthalmic Solution in Patients With Moderate to Severe Dry Eye Disease treatment 2 completed NCT03492541
Study of Efficacy and Tolerability of SYSTANE Complete in Patients With Dry Eye Disease No drug interventions treatment Not Available completed NCT05136924
IIT Assessing OC-01Nasal Spray on Symptoms of DED Following CXL No drug interventions treatment 2 unknown_status NCT02284516
A Study to Evaluate Efficacy and Safety of Lifitegrast in Subjects With Dry Eye (OPUS-3) treatment 3 completed NCT00599716
Safety and Efficacy Assessment of Vismed® (Sodium Hyaluronate) for the Treatment of Dry Eye Syndrome treatment 3 completed NCT04683796
Comparison of Efficacy Between 100% Platelet-rich Plasma and 100% Serum Eye Drops in Dry Eye Disease treatment 3 completed NCT05203796
The Evaluation of the Transcutaneous Electrical Stimulation Medical Device's Safety and Effectiveness in Treating the Patients With Dry Eye Disease No drug interventions treatment Not Available completed NCT03216096
Assessing Safety and Efficacy of DE-089 Ophthalmic Solution in Patients With Dry Eye Disease No drug interventions treatment 1 completed NCT03287635
Clinical Efficacy of H.P. Acthar Gel 80 U/ml to Improve the Signs and Symptoms in Subjects With Dry Eye Disease treatment 4 completed NCT04670263
Evaluating the Efficacy of Dry Eye (DE) Disease Treatment Using Novel Tear Film Imager (TFI) No drug interventions diagnostic 2 / 3 completed NCT01880463
Dry Eye Disease in the Vitamin D and Omega-3 Trial (VITAL) prevention Not Available unknown_status NCT04633863
Study on Safety and Performance of an Artificial Tear in Dry Eye Treatment in Subjects With Ocular Surface Inflammation No drug interventions treatment Not Available completed NCT05825586
PMCF Study to Evaluate Performance and Safety of "Distilled Waters-based Eyedrops" Used to Relieve Dry Eye Symptoms No drug interventions treatment Not Available completed NCT06370039
Study of INV-102 Ophthalmic Solution in Adults With Moderate to Severe Dry Eye Disease No drug interventions treatment 2 completed NCT02848222
Pilot Study for Investigating the Effect of the Bruder Eye Hydrating Compress on Contact Lens Discomfort in Contact Lens Wearers No drug interventions treatment Not Available completed NCT04139122
Safety, PK and Efficacy Study of SJP-0132 in Subjects With Dry Eye Disease No drug interventions treatment 1 / 2 completed NCT06120348
Study of Application of Pulse Electrical Stimulation Around Eye in Dry Eye Disease Patients Who Are Scheduled for Laser Epithelial Keratomileusis (LASEK) Surgery No drug interventions treatment Not Available recruiting NCT05865457
Efficacy and Safety of BUFY02 Versus TRB02 in the Treatment of Dry Eye Disease No drug interventions treatment Not Available not_yet_recruiting NCT00718926
The Evaluation of Thiol Redox Status in Conjunctiva of Dry Eye Patients No drug interventions Not Available Not Available unknown_status NCT03048526
Influence of Perfluorohexyloctane (NovaTears) on Tear Film Thickness in Patients With Mild to Moderate Dry Eye Disease No drug interventions treatment Not Available completed NCT06016166
Eye Mask on Sleep Quality and Tear Layer Function in Patients With Dry Eye Disease No drug interventions supportive_care Not Available not_yet_recruiting NCT02254265
Phase 2/3 Dose-Ranging Study of the Safety and Efficacy of OTX-101 in the Treatment of Keratoconjunctivitis Sicca No drug interventions treatment 2 / 3 completed NCT05119920
Safety and Efficacy of Pilocarpine Ophthalmic Topical Cream for the Treatment of Dry Eye Disease treatment 2 completed NCT02042820
Ocular Surface Immune Response in Dry Eye Disease No drug interventions Not Available Not Available completed NCT06225973
A Study of TL-925 Ophthalmic Emulsion as a Treatment for Dry Eye Disease No drug interventions treatment 2 active_not_recruiting NCT06210373
Assessment of Efficacy and Safety of the Use of Two Eye Gel Products Containing 5% Dexpanthenol in Patients With Moderate to Severe Dry Eye Syndrome No drug interventions treatment Not Available recruiting NCT04548427
Study to Evaluate the Efficacy and Safety of CKD-352 treatment 3 completed NCT00520260
Bromfenac 0.09% vs Ketorolac 0.4% for Cyclosporine Induction Phase treatment 4 completed NCT06544694
A Study to Investigate the Effect of 0.003% AR-15512 on Subjects With Dry Eye Disease treatment 3 not_yet_recruiting NCT06329791
A Phase 3 Study to Evaluate AZR-MD-001 in Patients With Abnormal Meibomian Gland Function and Dry Eye Disease (DED) No drug interventions treatment 3 recruiting NCT04030962
A Study of the Drugs AGN-242428 and AGN-231868 in Participants With Dry Eye Disease treatment 2 completed NCT00610480
Tear Film Stability After Instillation of Over-the-Counter (OTC) Artificial Drops treatment Not Available completed NCT06560580
Ditefossol Sodium 3% Eye Drops in Patients With Dry Eye treatment Not Available completed NCT01743729
A Phase 3 Study to Evaluate the Efficacy of Lifitegrast in Subjects With Dry Eye treatment 3 completed NCT05738629
Safety and Efficacy of Pluripotent Stem Cell-derived Mesenchymal Stem Cell Exosome (PSC-MSC-Exo) Eye Drops Treatment for Dry Eye Diseases Post Refractive Surgery and Associated With Blepharospasm No drug interventions treatment 1 / 2 not_yet_recruiting NCT04970329
Corneal Thickness Changes in Patient Undergoing Dry Eye Managment treatment Not Available unknown_status NCT05995392
The Effects and Safety of Topical Spironolactone Ophthalmic Solution, 0.005 mg/cc in Subjects With Dry Eye Disease No drug interventions treatment 0 not_yet_recruiting NCT06218992
Corneal and Tear Film Changes in Chinese Patients With Type 2 Diabetes No drug interventions Not Available Not Available recruiting NCT05285644
Study Evaluating the Safety and Efficacy of AR-15512 No drug interventions treatment 3 completed NCT06493604
A Trial to Assess the Safety and Efficacy of Subjects With Dry Eye Disease No drug interventions treatment 3 recruiting NCT01468168
A Study Assessing the Safety and Efficacy of DE-101 Ophthalmic Suspension in Dry Eye Patients No drug interventions treatment 2 completed NCT04819269
Tivanisiran for Dry Eye in Subjects With Sjögren's Syndrome No drug interventions treatment 3 completed NCT04734210
Research Study To See How Well An Eye Drop (SURF-200) Works, What Side Effects There Are, And To Compare It With Vehicle In Subjects With An Episodic Flare-Up of Dry Eye Disease No drug interventions treatment 2 completed NCT06146881
Effectiveness of Diquafosol Prophylactic Therapy to Prevent Dry Eye Disease for Cataract Surgery Patients in Indonesia No drug interventions prevention 2 recruiting NCT05660681
Evaluation of the Tolerability and Efficacy of CWT-f-002 Lubricant Eye Drops No drug interventions treatment Not Available completed NCT05695781
Assessment of the Safety and Efficacy of BRM421 Ophthalmic Solutions in Dry Eye Subjects. No drug interventions treatment 3 completed NCT06323395
Vizol S Lipid Balance Efficacy and Safety Study in Patients With Dry Eye No drug interventions supportive_care 3 completed NCT04357795
Effect of Cequa™ in Subjects With Dry Eye Disease No drug interventions treatment 4 completed NCT02764814
In Vivo Confocal Microscopic Analysis of Corneal Nerve Changes After ProKera Slim® for Dry Eye No drug interventions Not Available Not Available completed NCT06389214
A Clinical Trial to Assess the Efficacy and Safety of Subjects With Dry Eye Disease No drug interventions treatment 3 completed NCT00827255
Physician's Evaluation of Cyclosporine Ophthalmic Emulsion 0.05% No drug interventions Not Available Not Available completed NCT01478555
A Dose-Finding Study Comparing InSite Vision, Inc. 101 to Vehicle and DuraSite Alone for Dry Eye Disease No drug interventions basic_science 2 withdrawn NCT06483750
Preoperative iLux on Cataract Surgery Derived Dry Eye Disease Due to Meibomian Gland Dysfunction No drug interventions treatment Not Available recruiting NCT01276223
Evaluation of Anti-Inflammatory Treatment in Dry Eye Patients No drug interventions treatment 2 completed NCT06023108
Assess the Effects of Spectacles or Orthokeratology on Dry Eye Parameters in Children and Adolescents. No drug interventions treatment Not Available not_yet_recruiting NCT05759208
The Study Evaluating the Efficacy and Safety of OK-101 in Subjects With Dry Eye Disease No drug interventions treatment 2 completed NCT05841043
Efficacy and Safety of SHR8028 Eye Drops for the Treatment of Dry Eye Disease No drug interventions treatment 3 completed NCT06298890
The Pattern of Dry Eye Disease After Cataract Surgery No drug interventions Not Available Not Available recruiting NCT05745064
A Study of TL-925 as a Treatment for Dry Eye Disease No drug interventions treatment 2 completed NCT03108664
HELIX, a Double-masked Study of SYL1001 in Patients With Moderate to Severe Dry Eye Disease (DED) No drug interventions treatment 3 completed NCT05743764
HU007 in Patients With Dry Eye Syndrome No drug interventions treatment 3 completed NCT04946721
2177GCCC:ID'Ing tx Targets and Biomarkers for Ocular Surface Disease in Pt w/ oGVHD No drug interventions Not Available Not Available recruiting NCT03688802
Efficacy of OC-01 Nasal Spray on Goblet Cell and Meibomian Gland Stimulation No drug interventions treatment 2 completed NCT02554084
Optical Coherence Tomography of Tear Film Dynamics In-Vivo No drug interventions diagnostic Not Available completed NCT00758784
Safety and Efficacy of an Ophthalmic Solution in Dry Eye Disease No drug interventions treatment 2 completed NCT02120079
The Utility of IVCM to Assess Cellular Response and Efficacy of Long-term Topical Steroid Treatment in Patients With DED No drug interventions treatment 4 completed NCT05497479
Study Evaluating Techniques for Measuring Tear Production No drug interventions treatment 1 completed NCT00553579
The Relationship of Residence Time and Visual Effect of Optive and Systane in Dry Eye Subjects No drug interventions Not Available Not Available completed NCT05865379
Efficacy and Safety of BUFY01 Versus SVS20 in the Treatment of Dry Eye Disease No drug interventions treatment Not Available not_yet_recruiting NCT05056233
Systane Hydration in Subjects Undergoing Cataract Surgery No drug interventions treatment Not Available completed NCT06176651
Evaluation of Miebo (Perfluorohexyloctane) Eyedrops in Habitual Contact Lens Wearers No drug interventions treatment 4 completed NCT00760045
Clinical Pharmacological Study of AL-43546 Ophthalmic Product in Subjects With Shortened Tear Film Break Up Time No drug interventions basic_science 2 completed NCT05378945
Clinical Trial to Evaluate the Efficacy and Safety of OC-01 (Varenicline) Nasal Spray on Signs and Symptoms of Dry Eye Disease No drug interventions treatment 3 completed NCT06271005
Neurological Dry Eye Study Stimulating Both Lacrimal and Vagus Nerves No drug interventions treatment Not Available not_yet_recruiting NCT05238597
A Study to Evaluate the Safety, Tolerability, and Efficacy of A197 in Subjects With Dry Eye Disease No drug interventions treatment 2 completed NCT04734197
A Research Study To See How Well an Eye Drop, SURF-100 (A Mycophenolic Acid/Betamethasone Sodium Phosphate Combination), Works and What Side Effects There Are in Subjects With Dry Eye Disease No drug interventions treatment 2 completed NCT04656197
The Ocular Microbiome in Patients With Dry Eye Disease No drug interventions Not Available Not Available completed NCT05823961
PMCF Study to Evaluate Performance and Safety of "CLHA-based Eyedrops" Used to Improve Lacrimal Abnormalities No drug interventions treatment Not Available completed NCT03633461
Evaluation of the Efficacy of OC-02 Nasal Spray on Signs and Symptoms of Dry Eye Disease (the RAINIER Study) No drug interventions treatment 2 completed NCT06525961
iTear Single-center, Open-label, Single-arm Study No drug interventions treatment 4 not_yet_recruiting NCT06329661
A Clinical Trial to Evaluate the Corneal Endothelial Health of DED Subjects Treated With Cyclosporine No drug interventions treatment 4 active_not_recruiting NCT05003128
Changes in Tear Lipid Layer Thickness After Short Exposure to Light Emitting Diode Displays No drug interventions other Not Available completed NCT05356728
Comparison of Two Types of Artificial Tears No drug interventions treatment Not Available unknown_status NCT05493111
A Long-Term Safety Study Evaluating the Safety and Systemic Exposure of AR-15512 No drug interventions treatment 3 completed NCT04735393
A Multi-Center, Double-Masked, Randomized, Vehicle-Controlled, Parallel-Group Clinical Trial Evaluating the Safety of Reproxalap Ophthalmic Solution in Subjects With Dry Eye Disease No drug interventions treatment 3 completed NCT06064071
Clinical Study Evaluating Nordlys™ SWT IPL for Dry Eye Disease (DED) Due to MGD No drug interventions treatment Not Available recruiting NCT01014078
A Four Week Study of Azithromycin Ophthalmic Solution, 1% Versus Placebo in Subjects With Dry Eye Disease No drug interventions treatment 4 completed NCT03292809
CyclASol for the Treatment of Signs and Symptoms of Dry Eye Disease (DED) No drug interventions treatment 2 / 3 completed NCT06571656
Evaluation of the Safety and Tolerability of Ocular Lubricants No drug interventions treatment Not Available not_yet_recruiting NCT05724056
Idroflog® for Treatment of Dry Eye Disease (IDROFLOG) No drug interventions treatment Not Available not_yet_recruiting NCT06574685
Efficacy of Twinkle Eyez Supplementation in Improving Ocular Health and Immunity No drug interventions supportive_care Not Available completed NCT04711642
Comprehensive Study on Dry Eye and Ocular Surface Disease Prior and After Cataract Surgery No drug interventions treatment 3 unknown_status NCT05825599
PMCF Study to Evaluate Performance and Safety of "HPMC-based Eyedrops" Used to Relieve Dry Eye Symptoms No drug interventions treatment Not Available completed NCT05829499
PMCF Study to Evaluate Performance and Safety of "Xanoftal Next" No drug interventions treatment Not Available completed NCT05031806
Evaluation of the Safety, Tolerability and Efficacy of iNexin™ for the Treatment of the Signs and Symptoms Associated With Dry Eye Disease No drug interventions treatment 1 completed NCT01664949
A Study to Compare the Safety and Efficacy of A New Eye Drop Formulation With OPTIVE™ in Subjects With Dry Eye Disease No drug interventions treatment 3 completed NCT05888519
Evaluation of Safety and Tolerability of Investigational Ocular Lubricants No drug interventions treatment Not Available completed NCT05514041
A Randomized, Controlled, Double-masked, Investigator-initiated Trial to Evaluate Tear Film Quality and Stability in Subjects With Dry Eye Disease Using OC-01 (Varenicline Solution) Nasal Spray 0.03 mg as Compared to Vehicle Control Nasal Spray No drug interventions treatment 4 unknown_status NCT06565624
Evaluation of Reflex Tear Production No drug interventions basic_science Not Available not_yet_recruiting NCT01321424
Diurnal Variation in Tear Osmolarity No drug interventions Not Available Not Available completed NCT06244316
A Study to Evaluate Safety and Efficacy of a New Formulation of Recombinant Human Nerve Growth Factor (rhNGF) Eye Drop Solution in Patients With Dry Eye Disease No drug interventions treatment 2 recruiting NCT06444516
Study of Safety and Performance of a Novel Ocular Lubricant in Subjects With Dry Eye Disease No drug interventions treatment Not Available not_yet_recruiting NCT05310422
Safety Study of Tivanisiran to Treat Dry Eye No drug interventions treatment 3 completed NCT05271422
Application of Pulse Electrical Stimulation Around Eye in Dry Eye Disease Patients Scheduled for LASEK Surgery No drug interventions treatment Not Available completed NCT05857748
Examining the Clinical Characteristics, Treatment Patterns, Real-world Effectiveness, and Healthcare Resource Utilization of Patients With Dry Eye Disease No drug interventions Not Available Not Available withdrawn NCT05360966
Study Evaluating the Safety and Efficacy of AR-15512 (COMET-3) No drug interventions treatment 3 completed NCT05082974
Investigator Initiated Study to Assess the Efficacy of OC-01 (Varenicline) Nasal Spray on Signs and Symptoms of Dry Eye Disease Following Laser-assisted in Situ Keratomileusis (LASIK) No drug interventions treatment 3 completed NCT04201574
Phase 1/2a Safety and Efficacy of ALY688 Ophthalmic Solution in Subjects With Dry Eye Disease No drug interventions treatment 1 / 2 completed NCT04965974
Efficacy of Blue Wavelength in Managing Dry Eye No drug interventions treatment Not Available unknown_status NCT04498182
A Phase 2b Study Evaluating the Safety and Efficacy of AR-15512 Ophthalmic Solution for the Treatment of Dry Eye Disease No drug interventions treatment 2 completed NCT02943382
Fingerprick Autologous Blood (FAB) in Mebomian Gland Dysfunction (MGD) No drug interventions treatment Not Available unknown_status NCT00799682
Exploratory Study Comparing Signs and Symptoms in Patients With Ocular Hypertension or Glaucoma Using Xalatan R® or Travatan Z® No drug interventions supportive_care 4 completed NCT00404131
Study of INS365 Ophthalmic Solution in Subjects With Dry Eye Disease No drug interventions treatment 3 completed NCT05403827
A Study to Confirm the Efficacy and Safety of K-161 Ophthalmic Solution for Treatment of Moderate to Severe Dry Eye Disease No drug interventions treatment 3 completed NCT02260960
The Influence of PRN Dry Eye Omega-3 Nutritional Regimen on Tear Osmolarity In Cases Of Dry Eye Disease No drug interventions supportive_care 2 / 3 completed NCT05807360
PMCF Study to Evaluate Performance and Safety of "Hyaluronic Acid (HA)-Based Eyedrops" Used to Relieve Dry Eye Symptoms No drug interventions treatment Not Available completed NCT06120894
Strip Meniscometry in Dry Eye Evaluation No drug interventions Not Available Not Available completed NCT00831662
The Effects of Diquafosol Tetrasodium Ophthalmic Solution, 2% in Subjects With Dry Eye Disease (P08637) No drug interventions treatment 3 completed NCT04567329
Effect of NOV03 on Signs and Symptoms of Dry Eye Disease Associated With Meibomian Gland Dysfunction (Mojave Study) No drug interventions treatment 3 completed NCT04523129
ESSENCE 2: CyclASol for the Treatment of Signs and Symptoms of Dry Eye Disease (DED) No drug interventions treatment 3 completed NCT06424444
A Clinical Trial to Assess the Safety and Efficacy of Subjects With Dry Eye Disease No drug interventions treatment 3 recruiting NCT01775540
Systane Ultra Versus Maxidex Versus Saline No drug interventions treatment Not Available completed NCT05411367
A Study for Evaluation of the Efficacy and Safety of SI-614 Ophthalmic Solution in Patient With Dry Eye No drug interventions treatment 3 completed NCT00667004
Efficacy Study of Ecabet Ophthalmic Solution in Dry Eye Disease No drug interventions treatment 2 completed NCT03291704
Investigating the Effect of At Home Thermal Therapy on Dry Eye Patients With Meibomian Gland Dysfunction No drug interventions treatment Not Available unknown_status NCT04268069
Efficacy and Safety of PL9643 Ophthalmic Solution in Subjects With Dry Eye No drug interventions treatment 2 completed NCT03873246
Clinical Trial to Evaluate the Chronic Efficacy of OC-01 Nasal Spray on Signs of Dry Eye Disease (The MYSTIC Study) No drug interventions treatment 2 completed NCT04645446
Safety and Efficacy of Two Different Concentrations (0.5% and 1%) of Progesterone Topical Gel Compared to Placebo in Patients Diagnosed With Moderate to Severe Dry Eye Syndrome No drug interventions treatment 2 completed NCT02028312
A Phase IV, Randomized, Parallel Group, Investigator-Masked Evaluation of the Effect of Loteprednol Etabonate Ophthalmic Gel 0.5% on the Initiation of Dry Eye Treatment With Restasis® No drug interventions treatment 4 withdrawn NCT06016010
Efficacy and Safety of USL for Dry Eye Disease No drug interventions treatment 2 not_yet_recruiting NCT05370495
Study of SY-201 Ophthalmic Solution in Subjects With Dry Eye Disease No drug interventions treatment 1 / 2 completed NCT05056155
Systane Complete Multi-symptom Relief No drug interventions treatment Not Available completed NCT04762355
Study to Assess Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Doses of Palovarotene Ophthalmic Solution in Healthy Adult Subjects No drug interventions treatment 1 completed NCT00680108
A Study to Determine the Safety and Tolerability of Escalating Doses of INS365 Ophthalmic Solution No drug interventions treatment 2 completed NCT04658238
Ocular Microbiome and Immune System in Dry Eyes No drug interventions Not Available Not Available recruiting NCT02597803
Assessment of the Safety and Efficacy of RGN-259 Ophthalmic Solutions for Dry Eye Syndrome: ARISE-1 No drug interventions treatment 2 / 3 completed NCT03085290
Allogeneic Versus Autologous Serum Eye Drops No drug interventions treatment Not Available completed NCT02326090
Phase 2 Study With Cis-UCA Ophthalmic Solutions in Subjects With Dry Eye No drug interventions treatment 2 completed NCT01107964
Oral Omega-3 Fatty Acids in the Treatment of Dry Eye Syndrome No drug interventions treatment Not Available completed NCT06240364
Effects of AffronEye®/ Crocuvis+® on Dry Eye Syndrome No drug interventions supportive_care Not Available not_yet_recruiting NCT01252121
Residence Time Evaluation of Systane Ultra Lubricant Eye Drops vs. Hialid and Saline No drug interventions treatment Not Available completed NCT00344721
A Placebo Controlled Double Masked Clinical Assessment Study of Essential Fatty Acid Supplement and Its Effect on Patients With Apparent Aqueous Deficient Dry Eye Syndrome No drug interventions treatment Not Available completed NCT03569202
Piiloset Trehalose Emulsion Eye Drop Study in Moderate or Severe Dry Eye No drug interventions treatment Not Available completed NCT01850979
Treatment of Dry Eye Using 0.03% Tacrolimus Eye Drops No drug interventions treatment 4 completed NCT00991679
CXCL9, CXCL10, CXCL11, and CXCR3 in Dry Eye Syndrome No drug interventions Not Available Not Available completed NCT04343287
Safety and Efficacy of BRM421 for Dry Eye Syndrome Treatment treatment 2 / 3 completed NCT01745887
A Multi-Center Study Subjects With Dry Eye Syndrome treatment 1 completed NCT01162954
Phase I Study to Evaluate the Tolerability of Eye Drop DA-6034 in Healthy Volunteers treatment 1 completed NCT00535054
Study to Assess the Safety and Patients' Satisfaction of Tears Again* in the Treatment of Dry Eye Symptoms treatment Not Available completed NCT02066051
IPL and Meibomian Gland Expression to Treat Ocular Rosacea Ocular GVHD No drug interventions treatment Not Available completed NCT01013077
The Effect of a New Emulsion in Dry Eye Patients on Tear Layer Aberrometry, Contrast Sensitivity, and Reading Ability basic_science Not Available completed NCT02645045
Evaluation of Factors Affecting the Tear-film Lipid Layer Thickness No drug interventions Not Available Not Available completed NCT01733745
SYSTANE® Family - Meibomian Deficiency No drug interventions treatment Not Available completed NCT04877483
To Evaluate the Short-term and Long Term Efficacy of Acupuncture in Ocular and Oral Dryness Symptoms of Dry Eye Syndrome No drug interventions treatment Not Available recruiting NCT02369861
Study of ST266 Eye Drops in Treating Dry Eye treatment 1 completed NCT06190028
Evaluation of Performance and Safety of Carbopol 980 NF 0.2%- Based Medical Device in the Management of Patients With Glaucomar or Ocular Hypertension and Concomitant Dry Eye Syndrome on Multiple Long-term Topical Hypotensive Therapy No drug interventions treatment Not Available recruiting NCT02849093
Optical Coherence Tomography of Ocular Structures in Epiphora and Dry Eye Syndrome. No drug interventions Not Available Not Available unknown_status NCT03937271
Objective Measurement Methods for Autoimmune Disease and Dry Eye Syndrome No drug interventions Not Available Not Available withdrawn NCT04747288
Objective Measurement With TCM Pattern for AIDDES No drug interventions Not Available Not Available recruiting NCT02774707
Comparing the Quality of Topical Autologous Serum in Different Etiologies of Dry Eye Syndrome No drug interventions Not Available Not Available unknown_status NCT03938207
Dry Eye Syndrome, Healthy Control, Sjögren's Syndrome and Other Inflammation Disease in Taiwan Biobank No drug interventions Not Available Not Available not_yet_recruiting NCT03223909
Efficacy and Safety of the Ophthalmic Solution PRO-087 Versus Systane ® Ultra and Ultra Preservative Free (087LATAMFIV) treatment 4 completed NCT02376556
The Effect of Eyelid Surgery on Dry Eye - a Prospective Study No drug interventions Not Available Not Available completed NCT03652415
DRy Eye Outcome and Prescription Study No drug interventions Not Available Not Available unknown_status NCT01753752
Evaluation of the Corneal Residence Time of Chitosan-N-acetylcysteine Eye Drops in Patients With Dry Eye Syndrome After Single and Multiple Instillation basic_science 2 completed NCT00799552
Safety and Efficacy Study of RX-10045 on the Signs and Symptoms of Dry Eye No drug interventions treatment 2 completed NCT03576300
Comparison of Ocular Surface Features in Patients With Diabetes and Dry Eye Syndrome No drug interventions Not Available Not Available completed NCT00355459
A Prospective Clinical Study Assessing the Effects of Tetracycline Antibiotic on Tear Film and Tear Lipid Composition Within a Population of Patients Diagnosed With Blepharitis and Dry Eye Disease treatment Not Available withdrawn NCT03830359
Efficacy, Safety of T2769 in Dry Eye Disease No drug interventions other Not Available completed NCT01957670
Pilot Study to Clinical Evaluate Device Prototypes in Dry Eye Patients No drug interventions treatment Not Available withdrawn NCT05136170
Study to Evaluate Safety and Efficacy of Cenegermin (Oxervate®) vs Vehicle in Severe Sjogren's Dry Eye Disease treatment 3 completed NCT02455999
Dose-finding Study to Assess the Safety and Effect of SYL1001 in Patients With Ocular Pain treatment 2 completed NCT01339936
Evaluation of the Effect of Repeated Usage on the Tear Film Characteristics of an Investigational Eye Drop in Dry Eye Sufferers No drug interventions basic_science 2 / 3 completed NCT01970917
Effect of Olixia Pure® Eye Drops on Tear Film Thickness in Healthy Subjects No drug interventions basic_science 4 completed NCT05656196
VGH-DESJS-1 in Ocular and Oral Dryness Symptoms of Dry Eye Syndrome and Sjögren's Syndrome No drug interventions other Not Available completed NCT03764735
Study of SkQ1 as Treatment for Dry-eye Syndrome treatment 3 completed NCT02510235
Tolerability, Safety and Efficacy of Lubricin Eye Drops vs Sodium Hyaluronate Eye Drops in Subjects With Mod. Dry Eye No drug interventions treatment Not Available completed NCT01917539
Efficacy of Pulsed Light Therapy for Meibomian Gland Dysfunction and Dry Eye Syndrome No drug interventions treatment Not Available withdrawn NCT01579539
The Effect of Intravenous Glucocorticoids on the Tearfilm in Eyes With Thyroid-associated Ophthalmopathy treatment 3 completed NCT03364322
Influencing Factors on Dry Eye Syndrome and Ocular Surface Disease No drug interventions Not Available Not Available completed NCT03803722
To Demonstrate the Non-inferiority of Eyestil Protection® Compared to Vismed® in Terms of Clinical Performance No drug interventions other Not Available terminated NCT01797822
Effects of Dry Eye Treatments on the Ocular Surface treatment 4 completed NCT01382225
Sodium Hyaluronate Ophthalmic Solution, 0.18% for Treatment of Dry Eye Syndrome treatment 3 completed NCT06172530
Observational Study on the Improvement of Dry Eye Syndrome, Treatment Satisfaction, and Intraocular Tolerance With Diquasol Eye Drops No drug interventions Not Available Not Available recruiting NCT01864330
Influence of Lachrymal Substitutes on Tear Film Thickness in Patients With Moderate Dry Eye Syndrome No drug interventions treatment 4 completed NCT01744457
Reproducibility of Tearfilm Osmolarity Measurements Using TearLab® in Patients With Dry Eye Syndrome and Healthy Subjects No drug interventions diagnostic Not Available completed NCT01670357
Phase II Study of DA-6034 Eye Drops in Dry Eye Syndrome treatment 2 completed NCT04206020
Vehicle-Controlled Study of SkQ1 as Treatment for Dry-eye Syndrome treatment 3 completed NCT06475027
Exosome-miRNA and Transcriptome Profiling of Dry Eye Syndrome and Sjogren's Syndrome No drug interventions Not Available Not Available not_yet_recruiting NCT02758327
Evaluation of Tear Osmolarity Over Time With Sustained Use of Thera Tears Lubricating Drops treatment 4 completed NCT01228929
Non-invasive Ocular Surface Measurements Before and After Interventions No drug interventions diagnostic Not Available terminated NCT02798289
Acute Tear Production Following Single Use of the Oculeve Intranasal Neurostimulator No drug interventions supportive_care Not Available completed NCT03923244
Dry Eye Syndrome Description During Cataract Surgery, With Multimodal Analysis of the Ocular Surface No drug interventions diagnostic Not Available completed NCT03074344
Cross-linked Hyaluronic Acid and Coenzyme Q10 in the Treatment of Dry Eye No drug interventions treatment Not Available completed NCT01561040
Oral Nutrition Impact on Tear Film No drug interventions treatment 4 unknown_status NCT05878067
A Study to Assess Symptom Relief and Product Tolerability of ABBV-444 Drops in Adult Participants No drug interventions treatment 3 completed NCT04025801
Heidelberg In Vivo Confocal Microscopy to Evaluate the Ocular Surface Disorders of Healthy and Diseased Individuals No drug interventions Not Available Not Available unknown_status NCT05245604
Evaluating the Efficacy and Safety of TJO-087 in Moderate to Severe Dry Eye Disease Patients No drug interventions treatment 3 unknown_status NCT00765804
Safety and Efficacy Study of Iontophoresis and Dexamethasone Phosphate to Treat Dry Eye No drug interventions treatment 2 completed NCT00565669
Evaluation of Blink Tears and Systane Concomitant With Restasis for the Treatment of Dry Eye Symptoms No drug interventions other Not Available completed NCT02617095
Comparison of the Efficacy and Safety of T2762 Versus Optive® in the Treatment of Moderate to Severe Dry Eye Syndrome No drug interventions treatment Not Available terminated NCT02958514
Efficacy Comparison of Two Kinds of Treatment in Treating Dry Eye Caused by Meibomian Gland Dysfunction No drug interventions treatment Not Available completed NCT02777723
Study to Evaluate the Efficacy and Safety of CKD-350 No drug interventions treatment 3 unknown_status NCT04938908
Probiotic in Dry Eye Syndromes No drug interventions treatment 2 completed NCT00812721
Tears Substitutions and Their Effects on Higher Order Aberrometery No drug interventions supportive_care Not Available withdrawn NCT03666884
The Comparison of 50% AS Versus PFAT+ 0.05 % COE in Severe Dry Eye Syndrome No drug interventions treatment 4 completed NCT02315079
Point of Care Testing of Inflammatory Markers in Tears No drug interventions Not Available Not Available completed NCT02100787
Changes in Tear Osmolarity Over Time With Sustained Use of TheraTears No drug interventions treatment Not Available completed NCT01753687
Correlation of Different Signs for Assessment of Dry Eye Syndrome No drug interventions basic_science Not Available completed NCT00932477
Safety and Tolerability of Artificial Tears in Dry Eye Subjects No drug interventions Not Available Not Available completed NCT01387347
Safety and Efficacy of Thymosin Beta 4 Ophthalmic Solution in Patients With Dry Eye No drug interventions treatment 2 completed NCT06288945
Effect of an Educational Program on Health-related Outcomes of Patients With Dry Eye Syndrome No drug interventions treatment Not Available completed NCT03723798
Clinical Study to Investigate the Efficacy and Safety of Orally Administered SA001 in Patients With Dry Eye Syndrome. No drug interventions treatment 2 completed NCT03088605
Safety and Efficacy of TOP1630 for Dry Eye Syndrome No drug interventions treatment 2 completed NCT02078661
Safety and Efficacy of PG101 for Dry Eye Syndrome No drug interventions treatment 1 / 2 completed NCT01212471
A Dose Ranging Study to Evaluate Safety and Efficacy of Bromfenac Ophthalmic Solution in Dry Eye Disease No drug interventions treatment 3 completed NCT03833388
Study of TOP1630 for Dry Eye Syndrome No drug interventions treatment 2 / 3 completed NCT02092207
Phase 2 Study to Evaluation the Safety and Efficacy of Orally Administered KL7016 in Patients With Dry Eye Syndrome No drug interventions treatment 2 completed NCT02974907
Assessment of the Safety and Efficacy of RGN-259 Ophthalmic Solutions for Dry Eye Syndrome : ARISE-2 No drug interventions treatment 3 completed NCT00818909
Systane Clinical Experience Study No drug interventions treatment 4 completed NCT03404115
A Multi-Center, Randomized, Double Masked, Parallel-Group, Vehicle-Controlled, Clinical Study to Assess the Safety and Efficacy of Reproxalap Ophthalmic Solution in Subjects With Dry Eye Disease No drug interventions treatment 2 completed NCT02446015
Clinical Evaluation Following Use of SYSTANE® ULTRA in the Management of Dry Eye No drug interventions treatment Not Available completed NCT01632137
Efficacy and Safety of Rebamipide in Subjects With Dry Eye Syndrome No drug interventions treatment 3 completed NCT01733732
SYSTANE® BALANCE Symptoms (OSDI) & Inflammatory Biomarkers No drug interventions treatment Not Available completed NCT00514852
Safety and Efficacy of an Artificial Tear for the Treatment of Dry Eye No drug interventions treatment Not Available completed NCT01614600
Clinical Evaluation of a Daily Disposable Contact Lens in Symptomatic Weekly/Monthly Lens Wearers No drug interventions treatment Not Available completed NCT00522600
Eye Drop Use in Glaucoma Patients Through Patient Surveys and Video Observations No drug interventions Not Available Not Available completed NCT03539159
Assessment of the Mu-Drop System for Serum Eye Drops No drug interventions treatment Not Available unknown_status NCT03461575
Efficacy and Safety of HU007 Eye Drops in Patients With Dry Eye Syndrome No drug interventions treatment 3 completed NCT01675570
A Study of RX-10045 in the Treatment of Dry Eye Disease No drug interventions treatment 2 completed NCT06375499
Comparison of the Performance and Safety of T2769 Versus Hylo-Forte® in the Treatment of Moderate to Severe Dry Eye Syndrome. No drug interventions treatment Not Available not_yet_recruiting NCT03396913
Effectiveness of Intense Pulsed Light for Improving Dry Eye Syndrome No drug interventions treatment Not Available completed NCT00544713
Evaluate the Safety and Efficacy of a New Artificial Tear for Use After LASIK Surgery No drug interventions treatment Not Available completed NCT03066219
Safety and Efficacy of BRM421 for Dry Eye Syndrome No drug interventions treatment 2 completed NCT03622619
The Effect of Manuka Eye Drops on Tear Film Properties No drug interventions treatment Not Available completed NCT04884217
Treatment of Dry Eye Disease Using Pro-ocular™ - A Proof of Concept, Safety, and Efficacy Study No drug interventions treatment 2 unknown_status NCT02507934
Tolerability, Safety and Efficacy of Lubricin (150 µg/ml) Eye Drops Versus Sodium Hyaluronate (HA) 0.18% Eye Drops in Patients With Moderate Dry Eye (DE) No drug interventions treatment Not Available completed NCT01747616
Assessment of Safety and Tolerability of Chitosan-N-acetylcysteine Eye Drops in Subjects While Wearing Contact Lenses and Before Insertion of Contact Lenses No drug interventions treatment 1 completed NCT01753596
Assessment of Tear Film Thickness by Optical Coherence Tomography in Healthy Subjects and Subjects With Dry Eye Disease No drug interventions basic_science 3 withdrawn NCT01776658
Pilot Study to Evaluate SYL1001 Safety and Effect in Patients With Ocular Pain No drug interventions treatment 1 / 2 completed NCT02680158
A Study to Evaluate the Safety and Effectiveness of Oculeve Intranasal Lacrimal Neurostimulator in Participants With Dry Eye Syndrome No drug interventions supportive_care Not Available completed NCT03464357
Functional MRI Study of Cortical Modifications to Light Stimulation in Patients With Photophobia No drug interventions other Not Available unknown_status NCT01688726
Evaluation of SYSTANE® BALANCE in Dry Eye Subjects With Lipid Deficiency No drug interventions treatment Not Available completed NCT01942226
Investigation on Medical Management of Dry Eye Patients No drug interventions Not Available Not Available completed NCT00735865
Lid Margin And Conjunctival Microbial Flora Following Punctum Occlusion No drug interventions treatment Not Available completed NCT01198782
Evaluating Safety and Efficacy of FID 112903 Post Discontinuation of Long-term Use of RESTASIS® (Cyclosporine Ophthalmic Emulsion) 0.05% No drug interventions treatment 4 completed NCT01010282
Safety and Efficacy of Two Artificial Tears in Dry Eye Subjects No drug interventions Not Available Not Available completed NCT00442273
Comparison of Autologous Serum and Umbilical Cord Serum Eyedrops for Dry Eye Syndrome No drug interventions treatment Not Available completed NCT01808560
Treatment of Meibomian Gland Dysfunction Prior to Cataract Surgery No drug interventions treatment Not Available completed NCT03162094
Assessing the Safety and Efficacy of AVX-012 in Subjects With Mild-to-moderate Dry Eye Syndrome No drug interventions treatment 1 / 2 unknown_status NCT01541891
Efficacy and Safety of PRO-148 Ophthalmic Solution Versus SYSTANE® in the Treatment of Patients With Dry Eye Syndrome No drug interventions treatment 2 completed NCT01483989
In Vivo Measurement of Corneal Epithelial Changes in Dry Eye Patients No drug interventions treatment Not Available completed NCT01223040
An Open-Label, Single-Center Study Evaluating the Effect of Systane Balance on Video Ocular Protection Index (OPI) and Blink Patterns in Patients Diagnosed With Dry Eye No drug interventions treatment Not Available completed NCT04198740
Proteomic and Metabolomic Lacrimal Fingerprint in Diverse Pathologies of the Ocular Surface No drug interventions Not Available Not Available recruiting NCT02023268
Efficacy and Safety of T2762 and Vismed® in Dry Eye Syndrome No drug interventions treatment 3 completed NCT03982368
A Study to Evaluate Safety and Efficacy of rhNGF Eye Solution vs Vehicle in Patients With Moderate to Severe Dry Eye No drug interventions treatment 2 completed NCT01863368
Clinical Evaluation of Systane® ULTRA Compared to OPTIVE® in Ocular Surface Staining No drug interventions treatment Not Available completed NCT02522312
A Retrospective Analysis of Restasis® Benefits in Dry Eye Contact Lens Patients No drug interventions Not Available Not Available completed NCT02492412
Efficacy and Safety of HE10 for Dry Eye Syndrome No drug interventions treatment 3 completed NCT02917512
Efficacy and Safety Study of HU00701/HU007 Eye Drops in Patients With Dry Eye Syndrome No drug interventions treatment 2 completed NCT02101281
Safety and Efficacy of rhNGF Eye Drops at Different Doses in Patients With Dry Eye No drug interventions treatment 2 completed NCT04147650
Dose Ranging Study to Assess the Efficacy and Safety of Voclosporin Ophthalmic Solution in Subjects With Dry Eye Syndrome No drug interventions treatment 2 / 3 completed NCT03403023
Corneal Tear Film Imaging of the Cornea Before and After Restasis Therapy No drug interventions diagnostic Not Available unknown_status NCT02715323
Exploring Immune Cell Signatures in Autoimmunity and Dry Eye Syndrome No drug interventions Not Available Not Available completed NCT00893243
Efficacy Comparative Study Between Tears Again®, Opticol® and Optive® No drug interventions Not Available Not Available completed NCT01163643
Study to Assess the Safety and Efficacy of BOL-303242-X Ophthalmic Suspension in Dry Eye Syndrome No drug interventions treatment 2 completed NCT02106377
Using in Vivo Confocal Microscopy to Assess Cellular Response and Efficacy of Steroid Treatment in Dry Eye Disease treatment Not Available unknown_status NCT00611403
Safety and Efficacy Study of Cyclosporine Ophthalmic Emulsion in Post-LASIK Patients No drug interventions treatment 2 completed NCT01479790
Repeatability and Agreement of Anterior Segment Optical Coherence Tomography (AS-OCT) and Thermography No drug interventions screening Not Available completed NCT06174064
BroadBand Light for the Treatment of Dry Eye Disease No drug interventions treatment Not Available not_yet_recruiting NCT03804502
Pilot Study of TearCare System - Long-Term Extension No drug interventions treatment Not Available unknown_status NCT01278784
Local Tolerability of Chitosan-N-acetylcysteine Eye Drops in Healthy Young Volunteers No drug interventions treatment 1 completed NCT01294384
Safety and Efficacy Study of New Eye Drop Formulations With Refresh Tears® in Patients With Dry Eye Disease No drug interventions treatment 3 completed NCT00885079
Confirmatory Study of OPC-12759 Ophthalmic Suspension No drug interventions treatment 3 completed NCT04413279
Lipiflow Treatment Alone vs. Lipiflow + Dextenza Treatment for Dry Eye Disease No drug interventions treatment 4 completed NCT03358979
Three-dimensional Analysis of EMMPRIN on Conjunctival Epithelial Cells Surface in Severe Dry Eye Syndrome (ALTESSE) No drug interventions Not Available Not Available recruiting NCT06209879
Dual-Polymer Hydroxypropyl Guar-and Hyaluronic Acid Lubricants in Rheumatoid Arthritis No drug interventions treatment 4 recruiting NCT01840787
A Pilot Study on the Use of a Sensory Panel to Assess Comfort Between Three Different Contact Lenses No drug interventions Not Available Not Available completed NCT04485533
Clinical Investigation to Assess the Efficacy and the Safety of VisuXL® Gel Administered in Patients Affected by Moderate DED No drug interventions treatment Not Available unknown_status NCT02851654
Interest of Eye Movement Measurements in the Comprehension of Dry Eyes Symptoms No drug interventions Not Available Not Available completed NCT02313454
Evaluation of the Safety and Effectiveness of the Oculeve Intranasal Lacrimal Neurostimulator in Patients With Dry Eye No drug interventions treatment Not Available completed NCT02533154
Effect of Benzalkonium Chloride Containing Eye Drops on the Conjunctival Bacterial Flora of Dry Eye Patients No drug interventions basic_science 4 unknown_status NCT04127851
Evaluating HA 0.15% Compared With Cyclosporine 0.05%, and Efficacy of Combination Therapy in Dry Eye Disease Patients treatment 4 completed NCT01211951
A Study of KCT-0809 in Patients With Dry Eye Syndromes treatment 2 completed NCT02585453
Influence of Lachrymal Substitute Gels on Tear Film Thickness in Patients With Moderate to Severe Dry Eye Syndrome No drug interventions basic_science 4 completed NCT06499753
Differences in Dry Eye Symptoms Related to Geographic Location in Spain and Impact of Artificial Tears Use No drug interventions Not Available Not Available completed NCT04649177
Pilot Study to Investigate the Feasibility, Reliability and Efficacy of Utilizing OCT to Automate PROSE Fitting No drug interventions treatment Not Available completed NCT01434277
Safety Evaluation of a New Preservative in a Lubricating Eye Drop No drug interventions Not Available Not Available completed NCT03502447
Randomized Study of the Safety and Effectiveness of the TearCare System for the Signs and Symptoms of Dry Eye Disease No drug interventions treatment Not Available terminated NCT02121847
Investigation of Maintaining Visual Performance Achieved With Cyclosporine Therapy treatment 4 completed NCT00370747
Efficacy and Safety Study for Ecabet Ophthalmic Solution for Treating Dry Eye Syndrome treatment 2 completed NCT01176045
TearLab Refractive Surgery Dry Eye Study No drug interventions Not Available Not Available completed NCT05741398
Evaluation of Optical System in the Treatment of - Dry Eye Disease No drug interventions treatment Not Available recruiting NCT03518398
Effectiveness and Safety of Intense Pulsed Light in Patients With Meibomian Gland Dysfunction No drug interventions treatment 3 completed NCT01854905
An Observational Study of Dry Eye Prior to Laser-Assisted in Situ Keratomileusis (LASIK) Therapy No drug interventions Not Available Not Available completed NCT04104997
A Clinical Trial to Evaluate the Safety, Tolerability and Pharmacokinetic Characteristics of GLH8NDE After Single and Mutiple Ocular Administrations in Healthy Korean and Caucasian Volunteers No drug interventions treatment 1 completed NCT02956083
The Effect of Tear Supplements on Contact Lens Comfort No drug interventions treatment Not Available completed NCT05346783
Comparing Efficacy and Safety of TJO-083 in Dry Eye Disease Patients treatment 1 / 2 unknown_status NCT04679883
Phase 2 Clinical Trial to Evaluate the Efficacy and Safety of GLH8NDE in Patients With Dry Eye Disease No drug interventions treatment 2 unknown_status NCT05456061
Effect of ADDE on Tear Interferometry diagnostic Not Available completed NCT05162261
to Evaluate the Effectiveness and Safety of the Tixel® , VS LipiFlow® in the Treatment of Meibomian Gland Dysfunction No drug interventions treatment Not Available completed NCT01804361
Efficacy and Safety Study of Haporine-S for Treatment of Moderate to Severe Dry Eye Syndromes treatment 3 completed NCT02356328
NovaTears® Eye Drops Observational Study NT-003 No drug interventions Not Available Not Available completed NCT01364311
Treatment of Dry Eye With Supplements No drug interventions basic_science Not Available withdrawn NCT03140111
LAMELLEYE for the Treatment of Dry Eye Symptoms in pSS Patients No drug interventions treatment Not Available unknown_status NCT01135511
A Phase II, Dose Ranging Study Of CP-690,550 Eye Drops In Patients With Dry Eye Disease treatment 2 completed NCT03296111
Patients With Ocular Neuropathic Pain: Description of Pain and Impact on Their Quality of Life No drug interventions Not Available Not Available terminated NCT02815293
Topical Ophthalmic AGN-195263 for the Treatment of Evaporative Dry Eye No drug interventions treatment 3 terminated NCT04260893
Prospective Study To Assess The Safety And Effectiveness Of Tixel Treatment On Dry Eye Symptoms In Asian Patients No drug interventions treatment Not Available terminated NCT01471093
Safety Study of OPC-12759 Ophthalmic Solution treatment 1 completed NCT00234078
Dose-response Study of OPC-12759 Ophthalmic Suspension treatment 2 completed NCT04492878
Efficacy and Safety of Ikervis Under Controlled Environmental Conditions Environment treatment 4 completed NCT04342988
Effect of Cequa Treatment on Accuracy of Pre-operative Biometry & Higher Order Aberrations in Dry Eye Patients Undergoing Cataract Surgery treatment 4 completed NCT05148507
Optimization of the Ocular Surface Prior to Cataract Surgery Using PROKERA No drug interventions treatment Not Available unknown_status NCT04391907
Clinical Efficacy of Intense Pulsed Light(IPL) Procedure in Dry Eye Patient No drug interventions treatment Not Available withdrawn NCT03396809
Punctal Plugs and Iodine Related Discomfort No drug interventions supportive_care Not Available withdrawn NCT00721656
Phase 2 Study of KLS-0611 in Patients With Dry Eye Syndromes No drug interventions treatment 2 completed NCT04165785
Efficiency and Changes of Cytokines Expression in Tear After Intense Pulsed Light Treating Dry Eye Disease No drug interventions treatment Not Available completed NCT05201170
A Phase 3, Multi-Center Study Evaluating PL9643 in Patients With Dry Eye No drug interventions treatment 3 unknown_status NCT06388070
To Evaluate the Efficacy and Safety of HUC3-053 in Patients With Dry Eye Syndrome No drug interventions treatment 3 not_yet_recruiting NCT05017870
[KSR-001-P01]Clinical Trial to Evaluate the Safety, Tolerability and Pharmacokinetic Characteristic of KSR-001 No drug interventions treatment 1 completed NCT05778942
Investigation of Preservative-Free Ophthalmic Solution in Ocular Dryness No drug interventions Not Available Not Available completed NCT02970799
Tear Production by Nasal Neurostimulation Compared to Active Control No drug interventions other Not Available completed NCT03274999
Clinical Study to Evaluate Tear Characteristics Following Acute TrueTear™ Use No drug interventions treatment Not Available terminated NCT01558999
A Clinical Study Evaluating the Safety and Efficacy of SI-614 Ophthalmic Solution in Patients With Dry Eye No drug interventions treatment 2 completed NCT04184999
Effect of Intraoperative Dexamethasone on Post-op Dry Eye prevention 4 completed NCT02595606
0.3% Sodium Hyaluronate in the Treatment of Dry Eye of Diabetic Patients treatment 4 unknown_status NCT04730336
Assessing the Impact of Tixel Treatment of Periorbital Wrinkles on Dry Eye Symptoms and Signs No drug interventions treatment Not Available recruiting NCT05002036
Management of Dry Eye Disease After Cataract Surgery With Topical Hyaluronic Acid and Gingko Biloba No drug interventions treatment 4 completed NCT01027013
Safety and Efficacy Study of Rebamipide 2% Ophthalmic Suspension in Patients With Dry Eye treatment 2 completed NCT04668118
The Effect of 3% Diquafosol Ophthalmic Solution on Visual Display Terminal-associated Dry Eye treatment 4 unknown_status NCT00784719
A Prospective, Randomized, Placebo and Active Comparator Controlled Study of CP-690,550 in Subjects With Dry Eye. treatment 1 / 2 completed NCT04015219
Management of Signs and Symptoms Associated With Dry Eye Disease No drug interventions treatment Not Available terminated NCT05784519
Therapeutic Effect of Stem Cell Eye Drops on Dry Eye Disease No drug interventions treatment 0 not_yet_recruiting NCT04143841
Viveye Ocular Magnetic Neurostimulation System (OMNS) for the Management of Severe Dry Eye Disease No drug interventions treatment Not Available terminated NCT02356341
NovaTears® Eye Drops Observational Study NT-002 No drug interventions Not Available Not Available completed NCT00372034
The Effect of Punctal Plugs on Tear Volume and Osmolality No drug interventions treatment Not Available completed NCT03380624
Tear Lipid Layer Thickness With Emollient Eye Drops treatment 4 completed NCT03731624
Diadenosine Polyphosphates and Mucin Associated With Ocular Surface Disorders No drug interventions Not Available Not Available unknown_status NCT04637516
Evaluation of an Updated Version of the Program "BlinkBlink" for Alleviation of Dry Eye Symptoms Induced by Computer Work No drug interventions treatment Not Available completed NCT01427816
A Phase II Study of KCT-0809 in Patients With Dry Eye Syndrome treatment 2 completed NCT04674358
The TRANQUILITY Trial: Clinical Trial to Assess the Efficacy and Safety in Subjects With Dry Eye Disease treatment 2 / 3 completed NCT01268735
The Effect of Ocular Lubricant Eyedrops on Lid Parallel Conjunctival Folds and Other Signs and Symptoms of Dry Eye treatment 4 completed NCT04701086
3 Month Study of Cationorm Pro Versus Vismed in Adults With Dry Eye Disease Related to Keratitis or Keratoconjunctivitis No drug interventions treatment Not Available recruiting NCT02072122
Estrogen and the Outer Eye in Women During Fertility Treatment No drug interventions Not Available Not Available unknown_status NCT02420730
Safety, Tolerability and Systemic Pharmacokinetics of AGN-232411 in Healthy Participants and Participants With Dry Eye No drug interventions treatment 1 completed NCT02585648
Added Benefits of Lachrymal Substitute Gel During the Night in Patients With Moderate to Severe Dry Eye Syndrome No drug interventions basic_science Not Available completed NCT03524157
Safety and Tolerability of PRO-087 Versus Xyel Ofteno® and Systane Ultra®, on the Ocular Surface of Healthy Subjects treatment 1 completed NCT03318874
Optimization of the Treatment of Dry Eye Disease Caused by Meibomian Gland Dysfunction treatment 4 completed NCT02908282
Topical Omega-3 Fatty Acids (REMOGEN® OMEGA) in the Treatment of Dry Eye No drug interventions treatment Not Available completed NCT02683382
Effects of a Moisturizing Product on Dry Eye and Skin No drug interventions treatment Not Available completed NCT03968731
Meibomian Gland Dysfunction Management With ZEST Protocol No drug interventions treatment Not Available completed NCT02280473
A Safety and Efficacy Study of Refresh Optive® Gel Drops in Patients With Dry Eye Disease treatment 3 completed NCT03325673
Clinical Trial to Evaluate the Symptoms in Symptomatic Contact Lens Wearers Following Application of Intranasal Tear Neurostimulator Versus Control No drug interventions treatment Not Available completed NCT03302273
Corneal Epithelial Stem Cells and Dry Eye Disease No drug interventions treatment Not Available completed NCT01319773
Study of Two Formulations of Cyclosporine Ophthalmic Emulsion in Healthy Volunteers and in Patients With Dry Eye Not Available 1 completed NCT00502073
Study of Cyclosporine in the Treatment of Dry Eye Syndrome (ST-603-005) Not Available 3 completed NCT05825976
Omega-3 Fatty Acid Supplementation and Tear Film Quality in Celiac Patients No drug interventions treatment Not Available recruiting NCT02188160
Safety and Efficacy of KPI-121 in Subjects With Dry Eye Disease treatment 2 completed NCT06291194
Efficacy and Safety of AJU-S56 5% in Dry Eye Syndrome Patients No drug interventions treatment 3 recruiting NCT02013791
Phase 2 Study of a New Ophthalmic Formulation of Cyclosporine (Restasis® X) in Patients With Dry Eye Disease treatment 2 terminated NCT04147962
Intense Pulsed Light in Meibomian Gland Dysfunctions No drug interventions Not Available Not Available completed NCT00969280
Acupuncture for Dry Eye Syndrome No drug interventions treatment 3 completed NCT03874429
Efficacy of T2259 in DED No drug interventions treatment Not Available completed NCT05429229
Effect of Topical Antioxidants in Dry Eye Disease and Diabetic Retinopathy treatment 2 unknown_status NCT00549289
Study of Cyclosporine in the Treatment of Dry Eye Syndrome (ST-603-006) Not Available 3 completed NCT03399292
Effect of Lipid Based Eye Drops on Tear Film Lipid Layer Thickness No drug interventions Not Available Not Available unknown_status NCT04063644
Quality of Life and Visual Acuity of Visglyc Eye Drops on Dry Eye Patients No drug interventions supportive_care Not Available completed NCT05017844
[KSR-001-P02] Phase 2b/3 Study, Evaluate the Efficacy and Safety of KSR-001 in Patients With Dry Eye Syndrome No drug interventions treatment 2 / 3 completed NCT02871440
A Two Comparator, Controlled Phase 3 Study in Patients With and Without Evaporative Dry Eye No drug interventions treatment 3 completed NCT05763940
Efficacy of OmegaBoost to Increase Omega-3 Levels in Healthy Individuals No drug interventions supportive_care Not Available active_not_recruiting NCT03052140
Lamelleye vs Comparator for the Treatment of Dry Eye Disease No drug interventions treatment Not Available completed NCT02205840
A Clinical Study Evaluating the Safety and Efficacy of SI-614 Ophthalmic Solution in Patients With Dry Eye. No drug interventions treatment 2 / 3 completed NCT06543667
Limbal Stem Cell Derived Exosome (LSC-Exo) Eye Drop for Treatment of Dry Eye No drug interventions treatment 1 recruiting NCT00357201
Efficacy of T1675 Versus Placebo in Patients With Bilateral Treated Moderate Dry Eye Syndrome No drug interventions treatment 2 completed NCT03527212
A Study to Assess the Safety and Effectiveness of SJP-0035 for the Treatment of Patients With Dry Eye Disease No drug interventions treatment 3 completed NCT05990712
The Effect of a Pre-cataract Surgical Ocular Hygiene Regime on Microbial Load, Tear Osmolarity, Dry Eye, and Inflammatory Markers No drug interventions prevention 4 not_yet_recruiting NCT06351410
Assessment of Tear Production, Corneal Staining, and Comfort Level Wearing Different Types of Contact Lenses No drug interventions diagnostic Not Available not_yet_recruiting NCT01280110
The Effects of BAK on the Blood Aqueous Barrier of Pseudophakic Patients No drug interventions treatment 4 completed NCT01960010
A Safety and Efficacy Study of MIM-D3 Ophthalmic Solution for the Treatment of Dry Eye No drug interventions treatment 3 completed NCT02554981
Evaluation of Maintaining Visual Performance in Participants Who Engage in Electronic Visual Tasking While Using Restasis® No drug interventions treatment 4 completed NCT02298881
Ocular Surface Microbiome No drug interventions Not Available Not Available completed NCT05425914
Impact of Vitamin D3 Supplementation in Non-Sjogren Dry Eye Patients With Low Serum Vitamin D Level No drug interventions treatment 3 completed NCT03097614
Dry Eye Symptom Relief Assessment With Use of TrueTear in a Controlled Adverse Environment No drug interventions treatment Not Available completed NCT02435914
Safety, Efficacy, Tolerability and Pharmacokinetics of AGN-223575 Ophthalmic Suspension in Patients With Dry Eye Disease No drug interventions treatment 2 completed NCT02229955
Study of Tisporin Eye Drops Group and Restasis Eye Drops Group After Treatment, Each Treatment Group Comparisons for Evaluation of Efficacy and Safety in Moderate to Severe Dry Eye Disease No drug interventions treatment 3 completed NCT05292755
Effects of Carboxymethylcellulose Artificial Tears on the Eye Microbiome No drug interventions treatment 4 completed NCT02802150
The Effect of Oral Zanthoxylum Schinifolium Seed Oil in Individuals With Dry Eye Disease No drug interventions supportive_care Not Available completed NCT04889950
Clinical Study to Evaluate the Safety and Effectiveness of The Tixel Fractional System in the Treatment of Meibomian Gland Disfunction No drug interventions treatment Not Available completed NCT04835623
CEQUA for Sjogren's Syndrome Dry Eye No drug interventions treatment 4 completed NCT03706443
Tear Lipid Layer Thickness Changes With Use of Emollient and Non-Emollient Eye Drops No drug interventions treatment Not Available completed NCT02526290
Six Month Study to Evaluate the Safety and Effectiveness of the Intranasal Lacrimal Neurostimulator No drug interventions supportive_care Not Available completed NCT03827564
Goblet Cell Degranulation Produced by Intranasal Tear Neurostimulator (ITN) in Dry Eye Disease No drug interventions basic_science Not Available terminated NCT05653921
Prospective Study to Validate the Imaging Biomarker for NCP (R33) No drug interventions Not Available Not Available recruiting NCT00761202
Performance and Acceptance of Optive Versus Hylocomod Eyedrops in Patients With Dry Eye Symptoms No drug interventions treatment 4 completed NCT00731484
Validation of TearLab Osmometer - Human Factor Usability Report No drug interventions Not Available Not Available completed NCT02819284
Safety and Efficacy of KPI-121 Compared to Placebo in Subjects With Dry Eye Disease No drug interventions treatment 3 completed NCT04608084
Platelet Rich Plasma Eye Drops for Treatment of Ocular Surface Disease No drug interventions treatment 4 unknown_status NCT02117687
A Safety and Efficacy Study of OPTIVE FUSION™ With VISMED® Multi for the Management of Dry Eye No drug interventions treatment 4 completed NCT06406933
Salivary Conductivity Screening for Primary Sjögren's Syndrome No drug interventions Not Available Not Available recruiting NCT02028754
A Study of Sodium Carboxymethylcellulose for Post Cataract Surgery Dry Eye Symptoms No drug interventions treatment 4 completed NCT04425551
Effect of Micropulse Laser on Dry Eye Disease Due to Meibomian Gland Dysfunction No drug interventions treatment Not Available unknown_status NCT04413253
Xiidra vs. Xiidra + Dextenza Treatment for Dry Eye Disease No drug interventions treatment 4 terminated NCT04280653
An Open-Label, Multi-Center, Clinical Study Evaluating the Effect of the NDE L68 StableFit® Punctal Plug on the Tear Lake No drug interventions treatment Not Available completed NCT01202747
Evaluation of Screening Methods for Treatment of Meibomian Gland Dysfunction No drug interventions treatment 2 / 3 completed NCT01692145
A Parallel Group Phase II Study of KCT-0809 in Patients With Dry Eye Syndromes No drug interventions treatment 2 completed NCT05594745
Treatment Regimens in Meibomian Gland Dysfunction No drug interventions treatment 4 completed NCT03012698
Pilot Study for Testing Safety of Repetitive Magnetic Stimulation for Treatment of Dry Eye No drug interventions treatment Not Available completed NCT03417505
Tangible Hydra-PEG: A Promising Solution for Scleral Lens Wearers With Dry Eye No drug interventions supportive_care Not Available completed NCT04744805
Mask-associated Dry Eye Symptoms in China No drug interventions Not Available Not Available unknown_status NCT03162497
Effect of Topical Azithromycin on Tear Film Thickness in Patients With Meibomian Gland Dysfunction No drug interventions treatment 4 unknown_status NCT03162783
A Randomized, Double Masked, Clinical Study of Subjects With Dry Eye Syndrome No drug interventions other 2 completed NCT05219461
Pharmacokinetics, Safety, and Tolerability of rhEGF Eye Drops in Healthy Male Subjects No drug interventions screening 1 completed NCT03608761
Comparison Between Rebamipide 2% Versus Autologous Serum No drug interventions treatment 4 completed NCT05433428
Metabolomic Profile in Dry Eye Syndrome Patients. No drug interventions treatment 4 unknown_status NCT03723811
Clinical Study to Investigate the Efficacy and Safety of SJP002 Ophthalmic Solution in Patients With Dry Eye Syndrome. No drug interventions treatment 2 completed NCT00620893
Bilateral, Masked Comparison of PEG-400 Based Artificial Tear vs. Systane for Dry Eye Signs, Symptoms & Refractive Regression Associated With Myopic Laser in Situ Keratomilieusis (LASIK). No drug interventions treatment 4 completed NCT05121493
Study of Platelet Rich Plasma Drops to Moderate Clinically Significant Dry Eye No drug interventions treatment Not Available not_yet_recruiting NCT01568593
Comparison of the Efficacy and Safety of T2750 and Vismed® in the Treatment of Moderate to Severe Dry Eye Syndrome No drug interventions treatment 3 completed NCT02621593
Feasibility of IPL for Reducing Dry Eye Symptoms Caused by MGD No drug interventions treatment Not Available completed NCT03945071
The Effect of Punctal Plugs on Ocular Surface After Povidone-Iodine Preparation of Intravitreal Injection No drug interventions prevention Not Available completed NCT00756678
Efficacy and Acceptability of Two Lubricant Eye Drops No drug interventions treatment 4 completed NCT01459588
Safety, Efficacy, and Acceptability Study of an Eye Drop Formulation in Subjects With Dry Eye Disease No drug interventions treatment 3 completed NCT04685109
3 Month Study of Alocross Versus Vismed in Adults With Dry Eye Disease Related to Keratitis or Keratoconjunctivitis No drug interventions treatment Not Available recruiting NCT01015209
Safety and Tolerability of Chitosan-N-acetylcysteine Eye Drops in Healthy Young Volunteers No drug interventions basic_science 1 completed NCT04806256
CDSS of Traditional Chinese Medicine Intervention for Dry Eye Syndrome No drug interventions supportive_care Not Available unknown_status NCT03719885
TrueTear in Sjogren's Disease Patients No drug interventions treatment Not Available completed NCT04217785
Umbilical Cord Serum Versus Conventional Eyedrops No drug interventions treatment 1 / 2 unknown_status NCT06379685
Study to Evaluate the Safety and Tolerability of PRO-190 Ophthalmic Solution Compared to Systane Ultra® on the Ocular Surface. No drug interventions treatment 1 not_yet_recruiting NCT03617315
Crosslinked Hyaluronic Acid With Liposomes and Crocin in Dry Eye No drug interventions treatment Not Available completed NCT03821415
Effects of RP101 in Post-menopausal Women With Dry Eye Syndrome No drug interventions treatment 2 completed NCT05598437
Prevalence of Different Etiologies of Ocular Dryness in Patients Previously Diagnosed With Dry Eye Disease in A Sample of Egyptian Patients No drug interventions Not Available Not Available recruiting NCT05469932
Quantum Molecular Resonance Effects on Patients With Dry Eye Disease No drug interventions treatment Not Available unknown_status NCT01684852
Non Interventional Study to Evaluate the Efficacy and Tolerability of Ectoin Containing Ophthalmic Solution No drug interventions Not Available Not Available completed NCT06371300
Photobiomodulation With REd vs BluE Light (REBEL) No drug interventions treatment Not Available recruiting NCT06262100
Lubricating Effectiveness of Carragelose Eye Drops in Patients Affected by Mild to Moderate Dry Eye No drug interventions treatment Not Available recruiting NCT05618470
Wumeiwan Jiawei Fang Use in Patients With Blepharospasm No drug interventions treatment 2 / 3 recruiting NCT04863742
Evaluation Of Vision Recovery And Comfort Index In Patients With Borderline/Mild Dry Eyes Undergoing FLACS With Premium IOL No drug interventions treatment 4 unknown_status NCT05598242
Amniotic Membrane Treatment for Hyposecretory Dry Eye No drug interventions treatment 3 completed NCT00284999
Soothe Versus Refresh No drug interventions treatment 4 completed NCT05414799
Effect of Exercises on Computer Vision Syndrome No drug interventions treatment Not Available unknown_status NCT05424549
A Clinical Trial to Evaluate the Safety and Efficacy of Rreproxalap in Adults With Dry Eye Disease No drug interventions treatment 2 completed NCT05887336
Intra-Nasal Mechanical Stimulation (INMEST) as a Treatment Method for the Relief of Symptoms of Dry Eye No drug interventions treatment Not Available active_not_recruiting NCT00198536
Efficacy and Safety Study for Ecabet Ophthalmic Solution for Treating Dry Eye Syndrome No drug interventions treatment 2 / 3 completed NCT00739713
Effects of Sea Buckthorn Oil on Dry Eye No drug interventions treatment Not Available completed NCT01882413
A Study to Determine the Prevalence of Inflammatory Dry Eye Disease in Patients Prior to Cataract Removal No drug interventions Not Available Not Available completed NCT02980913
Difference in the Frequency of Use of Lachrymal Substitutes in Patients With Moderate to Severe Dry Eye Syndrome No drug interventions basic_science Not Available completed NCT02910713
Evaluation of Dry Eye Symptoms in CAE With Application of Intranasal Neurostimulation No drug interventions treatment Not Available completed NCT02403219
Paralysis of the Orbicularis Muscle of the Eye in the Treatment for Dry Eye No drug interventions treatment 1 completed NCT02461719
Efficacy and Safety Study of TJCS for Treatment of Moderate to Severe Dry Eye Syndromes No drug interventions treatment 3 completed NCT00475319
Late Phase 2 Study of OPC-12759 Ophthalmic Suspension No drug interventions prevention 2 completed NCT01890941
A Late Phase II Study of KCT-0809 in Patients With Dry Eye Syndromes No drug interventions Not Available 2 completed NCT06404541
A Comparative Study Between Preservative With Benzalkonium Chloride vs Preservative Free Eye Drops on the Ocular Surface No drug interventions treatment 4 active_not_recruiting NCT06089317
Traditional Chinese Medicine Ultrasonic Atomization Treatment for Dry Eye Disease No drug interventions treatment Not Available recruiting NCT00761917
Diagnostic Evaluation of the Tear Film No drug interventions Not Available Not Available completed NCT05184517
A Feasibility Study to Evaluate the Tolerability of Oph1 Compared to Restasis in Healthy Volunteers No drug interventions other 0 completed NCT00818324
Long Term Administration Study of OPC-12759 Ophthalmic Suspension No drug interventions treatment 3 completed NCT05733624
Clinical Trial to Evaluate the Safety and Efficacy of SCAI-001 Compared to Restasis No drug interventions treatment 2 completed NCT01711424
An Observational Study of OPTIVE PLUS® for the Treatment of Dry Eye Disease No drug interventions Not Available Not Available completed NCT02767258
Effect of Nursing Care on Prevention of Dry Eye No drug interventions prevention Not Available unknown_status NCT04493658
Differential Diagnosis of Sjögren's Versus Non-Sjögren's Dry Eye No drug interventions Not Available Not Available completed NCT05992922
A Study to Assess the Safety and Efficacy of IC265 Ophthalmic Solution for Dry Eye in Adult Participants No drug interventions treatment 2 recruiting NCT02014922
A Study to Determine the Relief of Dry Eye Symptoms With the Use of TheraTears® Products (DUNLIN) No drug interventions treatment 4 completed NCT06317922
Evaluation of Dry Eye Disease's Signs in Patients Who Were Administered Intravitreal Anti-VEGF Injections No drug interventions treatment Not Available recruiting NCT00832130
Treatment of Meibomian Gland Dysfunction and Evaporative Dry Eye No drug interventions treatment Not Available completed NCT00797030
Topical Cyclosporine for the Treatment of Dry Eye in Patients Infected With the Human Immunodeficiency Virus No drug interventions treatment 4 unknown_status NCT03803748
A Non-inferiority Study of Eyestil® Plus Multidose Versus Vismed Multi® No drug interventions other Not Available completed NCT05814757
OTX-DED for the Short-term Treatment of the Symptoms of Dry Eye Disease (DED) No drug interventions treatment 2 completed NCT00469157
Refractive Surgery and Optive Compatibility Study No drug interventions supportive_care 4 completed NCT01102257
Dry Eye Assessment and Management: Feasibility Study No drug interventions treatment 2 / 3 completed NCT01072526
Pilot Study of a Homeopathic Therapy in Combination With Cyclosporin (Restasis) in the Treatment of Dry Eye Disease No drug interventions treatment 2 terminated NCT02813265
Safety and Efficacy of KPI-121 in Subjects With Dry Eye Disease No drug interventions treatment 3 completed NCT06220474
Therapeutic Efficacy and Safety of Non-Invasive RF Treatment in Refractory MGD No drug interventions treatment Not Available recruiting NCT03937882
Assessment of the Safety and Efficacy of RGN-259 Ophthalmic Solutions for Dry Eye Syndrome: ARISE-3 No drug interventions treatment 3 completed NCT01496482
Comparison of Evaporimetry With the Established Methods of Tear Film Measurement No drug interventions Not Available Not Available completed NCT06427031
Comparing Efficacy and Safety of TJO-083 in Dry Eye Diseases Patients No drug interventions treatment 3 recruiting NCT03395431
Fingerprick Autologous Blood (FAB) in Severe Dry Eye Disease (DED) No drug interventions treatment Not Available unknown_status NCT00987727
Safety and Efficacy of Carboxymethylcellulose for Ocular Surface Integrity in Symptomatic Dry Eye No drug interventions treatment 4 completed NCT03135327
Clinical Applications of Advanced Ophthalmic Imaging No drug interventions supportive_care Not Available recruiting NCT02011776
A Randomized, Parallel-Group Comparison Study of Topical Corticosteroids in Dry Eye Patients With Sjögren Syndrome No drug interventions Not Available Not Available completed NCT03697876
Safety and Tolerability of the Ophthalmic Gel PRO-165 Versus Artelac® Nightime Gel No drug interventions treatment 1 active_not_recruiting NCT06188260
Efficacy of a New Nanoemulsion Artificial Tear in Dry Eye Disease Management No drug interventions treatment 2 recruiting NCT05042960
Computer Screen Properties Study No drug interventions prevention Not Available completed NCT02782260
Assessment of the Efficacy of Ocular Dipyridamole in the Treatment of Dry Eye Symptomology in Subjects With Pterygium No drug interventions treatment 2 unknown_status NCT04384991
HU007 Eye Drops in Patients With Dry Eye Syndrome No drug interventions treatment 3 completed NCT04597762
Effect of Ciclosporin Eyedrops on Sjögren Syndrome No drug interventions treatment Not Available completed NCT03161080
Effect of Single Instillation of Three Different Topical Lubricants on Tear Film Thickness in Patients With Dry Eye Syndrome No drug interventions basic_science Not Available completed NCT00788229
Efficacy and Safety Study of ATs in Patients With Dry Eye Syndrome No drug interventions treatment 2 completed NCT03183089
Comparative Study of Rohto Dry-Aid® and Systane® Ultra in Patients With Dry Eye No drug interventions treatment 4 completed NCT04000789
The Effect of Combination of Vitamin A, Vitamin E, Sodium Hyaluronate 0.15% Eye Drop Compared With Sodium Hyaluronate 0.1% Eye Drop to Tear Film Stability and Conjunctival Goblet Cells Density in Patient With Non-Proliferative Diabetic Retinopathy (NPDR), and Proliferative Diabetic Retinopathy (PDR) No drug interventions treatment Not Available unknown_status NCT02608489
Clinical Effects and Safety of 3% Diquafosol After Cataract Surgery No drug interventions treatment Not Available completed NCT06163989
Protecting the Eyes of Gamers With Lubricating Eyedrops No drug interventions treatment Not Available not_yet_recruiting NCT02385292
Multicenter Trial Evaluating Quality of Tears Produced by Nasal Neurostimulation No drug interventions basic_science Not Available completed NCT02252744
Prevalence of Dry Eye Disease in Patients Diagnosed With Rheumatoid Arthritis No drug interventions Not Available Not Available completed NCT00349440
Efficacy of Cyclosporine for the Prevention and Treatment of Dry Eye Symptoms Following LASIK or Photorefractive Keratectomy No drug interventions treatment 4 completed NCT04426240
The Effect of Cyclosporin Before Cataract Surgery No drug interventions prevention 4 completed NCT02617667
CyclASol for the Treatment of Moderate to Severe Dry-eye Disease (DED) No drug interventions treatment 2 completed NCT00548301
Study of Cyclosporine in the Treatment of Dry Eye Syndrome (ST-603-007) No drug interventions Not Available 3 completed NCT00938704
Study to Compare the Efficacy and Safety of Two Non-Preserved Artificial Tears for the Treatment of Dry Eye Signs and Symptoms No drug interventions treatment 4 completed NCT02031172
Effects of Sustained Reading on the Ocular Surface No drug interventions Not Available Not Available terminated NCT02553772
A Safety and Efficacy Study of a New Eye Drop Formulation in Patients With Dry Eye Disease. No drug interventions treatment 3 completed NCT03226769
Safety and Efficacy of TrueTear™ for the Treatment of Meibomian Gland Disease No drug interventions treatment Not Available completed NCT04310969
Clinical Effect of MiboFlo in Dry Eye Patients No drug interventions treatment Not Available completed NCT05945069
Feasibility of Dynamic Muscle Stimulation + Radiofrequency for Improving Blink Quality in Subjects With Dry Eye Disease No drug interventions treatment Not Available recruiting NCT05096546
The Proportion of Patients Diagnosed With Dry Eye by the Asia Dry Eye Society (ADES) Criteria in Taiwan (DECS-TW) No drug interventions Not Available Not Available unknown_status NCT02965846
Topical Ophthalmic AGN-195263 for the Treatment of Evaporative Dry Eye No drug interventions treatment 3 terminated NCT00386646
Comparative Study of 0.5% Carboxymethylcellulose With 0.005% Stabilized Oxychlorocomplex (PURITE™) Versus 0.5% Carboxymethylcellulose in the Treatment of Dry Eye No drug interventions treatment 4 completed NCT01826812
Impairment of Reading Ability in Dry Eye Patients No drug interventions Not Available Not Available completed NCT04237012
ACCURATE Study for Subjects With Dry Eyes No drug interventions treatment 4 completed NCT01768312
Study of Cyclosporine Ophthalmic Soution Group and Cyclosporine Ophthalmic Suspension Group No drug interventions treatment 3 completed NCT01382810
Altaire Gel Forming Solution Versus Refresh Tears for the Treatment of Dry Eye Signs and Symptoms No drug interventions treatment 4 unknown_status NCT06174181
Preventive TREatment of Dry Eye in Patients Receiving Repeated Intravitreal Injections for Age-related Macular Degeneration No drug interventions prevention Not Available recruiting NCT06337981
Efficacy and Safety of AJU-S56 in Dry Eye Syndrome Patients No drug interventions treatment 2 completed NCT03952481
Effect of Lifitegrast 5% on Tear Film Markers No drug interventions diagnostic 4 withdrawn NCT04454281
Topical Naloxone to Diagnose Ocular Pain No drug interventions diagnostic 1 completed NCT06004895
Mechanisms of Light-based Therapies for Dry Eye Disease No drug interventions treatment Not Available recruiting NCT02585414
Assessment of TFT by OCT in Healthy Subjects and Subjects With DES No drug interventions Not Available Not Available unknown_status NCT03747614
Ocular Micro-vascular Research Base on Functional Slip Lamp Biomicroscopy No drug interventions health_services_research 4 unknown_status NCT05481450
Efficacy and Safety Safety of Nutritears® in Adults With Dry Eye Syndrome No drug interventions treatment Not Available completed NCT02986750
Influence of Three Different Formulations of Lachrymal Substitutes on Tear Film Thickness and Other Signs and Symptoms in Patients With Moderate to Severe Dry Eye Syndrome No drug interventions basic_science 4 completed NCT02455050
A Study to Compare a New Eye Drop Formulation With Systane® Gel Drops and Genteal® Lubricant Gel Drops for Moderate to Severe Dry Eye Relief No drug interventions treatment 3 completed NCT05304650
A Usability Study of External Neuromodulation With iTEAR100 Generation 2 No drug interventions other 4 unknown_status NCT06364943
Tear Ferning Test for Dry Eye Diagnosis No drug interventions diagnostic Not Available recruiting NCT03180047
Dry Eye Symptom Relief Assessment With Use of TrueTear in a Controlled Adverse Environment No drug interventions treatment Not Available completed