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Obstructive Hypertrophic Cardiomyopathy
go.drugbank.com/conditions/DBCOND0057747Paroxysmal Supraventricular Tachycardia (PSVT)
go.drugbank.com/conditions/DBCOND0075436Skin Irritation
go.drugbank.com/conditions/DBCOND0062614Tonsillitis
go.drugbank.com/conditions/DBCOND0014060Disulfiram Action Pathway
smpdb.ca/view/SMP0000429Drug actionDisulfiram is a drug used in the treatment of cocaine addiction and chronic alcoholism. … This causes more dopamine to accumulate in the axon terminal and more dopamine is released.
Drugs: Pyridoxal phosphate · Ademetionine · Ascorbic acid · Aspartic acid · Adenosine phosphate · Tyrosine +27 moreEthanol GABA Agonist Action Pathway
smpdb.ca/view/SMP0125151Drug actionThe main effects are seen by the binding to GABA receptors, glycine receptors, and glutamate receptors. … Hyperpolarization prevents depolarization and excitability of the neuron which causes a sedative effect in the brain.
Cocaine metabolism
smpdb.ca/view/SMP0125265MetabolicNorcocaine, benzoylecogonine, and cocaethylene all diffuse through the hepatic cell membrane into the blood where they travel to the kidney and are excreted renally. … However, cocaethylene is an active metabolite that is much more toxic than cocaine and has a higher affinity for dopamine re-uptake receptors, and therefore will activate similar pathways to cocaine.