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Fish oil Prostaglandin G/H synthase 1 and 2 anti-inflammatory Action Pathway
smpdb.ca/view/SMP0126563Drug actionFish oil is made of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA). … Fish oil is administered as an oral capsule or tablet, it can also be found as a parenteral emulsion when oral or enteral nutrition is not possible, insufficient, or contraindicated for different reasons
Castor Oil Action Pathway
smpdb.ca/view/SMP0174887Drug actionCastor Oil may also promote ulcer healing by increasing mucus and bicarbonate secretion and thickening the mucosal bilayer so the mucosa can generate new cells. … Castor Oil stimulates prostaglandin receptors on parietal cells in the stomach to reduce gastric acid secretion. Castor Oil activates prostaglandin EP3 receptors in parietal cells.
Drugs: ATP · Potassium cation · Magnesium cation · Zinc · Cyclic adenosine monophosphate · Pyrophosphoric acid +1 moreGlutaminolysis and Cancer
smpdb.ca/view/SMP0002298DiseaseThe glutaminolysis pathway catabolizes glutamine to generate ATP and lactate. … The transportation of glutamine in and out regulates mTOR activation to coordinate cell growth and proliferation.
Drugs: Pyridoxal phosphate · Pyruvic acid · Biotin · Aspartic acid · L-Glutamine · Succinic acid +9 moreNicotinate and Nicotinamide Metabolism
smpdb.ca/view/SMP0000048MetabolicNicotinate (niacin) and nicotinamide - more commonly known as vitamin B3 - are precursors of the coenzymes nicotinamide-adenine dinucleotide (NAD+) and nicotinamide-adenine dinucleotide phosphate (NADP … Nicotinamide mononucleotide adenylyltransferase then transfers an adenylate group to form nicotinic acid adenine dinucleotide (NaAD).
Fructose and Mannose Degradation
smpdb.ca/view/SMP0000064MetabolicFructose causes less of an insulin response compared to glucose and thus may be a preferred sugar for diabetics. … Fructose and mannose are monosaccharides that can be found in many foods. Fructose can join with glucose to form sucrose. Mannose can be converted to glucose. Both may be used as food sweeteners.
Androgen and Estrogen Metabolism
smpdb.ca/view/SMP0000068MetabolicMany steroid hormones are transformed by sulfatases, dehydrogenases and glucuronide transferases to enhance their solubility and to facilitate their elimination. … This pathway describes the inactivation and catabolism of male (androgen) and female (estrogen) hormones.
NAD+ Signalling and Aging
smpdb.ca/view/SMP0084271SignalingAn interesting link has emerged between NAD+ metabolism, SIRT1, SIRT3, and mitochondrial function. … NR and PARP inhibitors increased life span in worms via activation of the mitochondrial unfolded protein response UPRmt by sir2.1.
Glycine and Serine Metabolism
smpdb.ca/view/SMP0000004MetabolicSerine is central to the synthesis and breakdown of the other two amino acids. … then phosphoserine (via phosphoserine transaminase) and finally to serine (via phosphoserine phosphatase).
Drugs: Pyridoxal phosphate · Tetrahydrofolic acid · Ademetionine · Pyruvic acid · Arginine · Adenosine phosphate +26 moreTaurine and Hypotaurine Metabolism
smpdb.ca/view/SMP0000021Metabolicand returning them to the bile. … This includes acids such as chenodeoxycholic acid and cholic acid, and in turn the formation of bile salts occurs.
Pantothenate and CoA Biosynthesis
smpdb.ca/view/SMP0000027MetabolicPantothenic acid, pantetheine 4’-phosphate and pantetheine are all found in red blood cells. … It is a precursor of coenzyme A, which is an essential part of many reactions in the body, specifically important in the production of compounds like cholesterol and different fatty acids.