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Displaying targets 4451 - 4475 of 6103 in total
TargetOrganismDescription# of Drugs
Propionyl-CoA carboxylase complex B subunitStreptomyces coelicolorNot Available1Details
Proprotein convertase subtilisin/kexin type 9HumansCrucial player in the regulation of plasma cholesterol homeostasis. Binds to low-density lipid receptor family member...  more12Details
ProsaposinHumansSaposins are specific low-molecular mass non-enzymatic glycoproteins that act as activator proteins for lysosomal sph...  more4Details
Prosaposin receptor GPR37HumansG protein-coupled receptor that plays a role in several physiological pathways such as resolution of inflammatory pai...  more1Details
Prostacyclin receptorHumansReceptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins whic...  more18Details
Prostacyclin synthaseHumansCatalyzes the biosynthesis and metabolism of eicosanoids. Catalyzes the isomerization of prostaglandin H2 to prostacy...  more3Details
Prostaglandin D2 receptorHumansReceptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulat...  more9Details
Prostaglandin D2 receptor 2HumansReceptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin-...  more23Details
Prostaglandin E synthaseHumansTerminal enzyme of the cyclooxygenase (COX)-2-mediated prostaglandin E2 (PGE2) biosynthetic pathway. Catalyzes the gl...  more5Details
Prostaglandin E synthase 3HumansCytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostag...  more3Details
Prostaglandin E2 receptor EP1 subtypeHumansReceptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a pho...  more19Details
Prostaglandin E2 receptor EP2 subtypeHumansReceptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adeny...  more18Details
Prostaglandin E2 receptor EP3 subtypeHumansReceptor for prostaglandin E2 (PGE2). The activity of this receptor can couple to both the inhibition of adenylate cy...  more17Details
Prostaglandin E2 receptor EP4 subtypeHumansReceptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adeny...  more13Details
Prostaglandin E2 ReceptorsHumansIncludes subtypes EP1 through 4.4Details
Prostaglandin F2-alpha receptorHumansReceptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activ...  more18Details
Prostaglandin G/H synthase 1HumansDual cyclooxygenase and peroxidase that plays an important role in the biosynthesis pathway of prostanoids, a class o...  more155Details
Prostaglandin G/H synthase 2Canis lupus familiarisNot Available6Details
Prostaglandin G/H synthase 2HumansDual cyclooxygenase and peroxidase in the biosynthesis pathway of prostanoids, a class of C20 oxylipins mainly derive...  more169Details
Prostaglandin reductase 1HumansNAD(P)H-dependent oxidoreductase involved in metabolic inactivation of pro- and anti-inflammatory eicosanoids: prosta...  more5Details
Prostaglandin reductase 2HumansFunctions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto...  more2Details
Prostaglandin-H2 D-isomeraseHumansCatalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a pote...  more2Details
ProstasinHumansPossesses a trypsin-like cleavage specificity with a preference for poly-basic substrates. Stimulates epithelial sodi...  more1Details
Prostate stem cell antigenHumansMay be involved in the regulation of cell proliferation. Has a cell-proliferation inhibition activity in vitro1Details
Prostate-specific antigenHumansHydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum7Details
Displaying targets 4451 - 4475 of 6103 in total