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Displaying targets 151 - 175 of 6103 in total
TargetOrganismDescription# of Drugs
4-hydroxy-3-methylbut-2-enyl diphosphate reductaseEscherichia coli (strain K12)Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diph...  more2Details
4-hydroxy-tetrahydrodipicolinate reductaseMycobacterium tuberculosisCatalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. Can use both NADH and ...  more1Details
4-hydroxy-tetrahydrodipicolinate reductaseEscherichia coli (strain K12)Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. Can use both NADH and ...  more2Details
4-hydroxy-tetrahydrodipicolinate synthaseThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolin...  more1Details
4-hydroxybenzoyl-CoA thioesterasePseudomonas sp. (strain CBS-3)Hydrolyzes 4-hydroxybenzoate-CoA, and to a lesser extent benzoyl-CoA and 4-chlorobenzoate-CoA. Not active against ali...  more3Details
4-hydroxybenzoyl-CoA thioesteraseArthrobacter sp.Not Available4Details
4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomeraseClostridium aminobutyricumCatalyzes the reversible conversion of 4-hydroxybutyryl-CoA to crotonyl-CoA. The mechanism of the reaction seems to g...  more1Details
4-hydroxymandelate synthaseAmycolatopsis orientalisRequired to synthesize hydroxyphenylglycine, a recurring skeletal component of nonproteinogenic macrocyclic peptide a...  more1Details
4-hydroxyphenylpyruvate dioxygenaseStreptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680)Not Available1Details
4-hydroxyphenylpyruvate dioxygenaseHumansCatalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid, one of the steps in tyrosine catabolism...  more4Details
4-hydroxythreonine-4-phosphate dehydrogenaseEscherichia coli (strain K12)Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric...  more1Details
4-trimethylaminobutyraldehyde dehydrogenaseHumansConverts gamma-trimethylaminobutyraldehyde into gamma-butyrobetaine with high efficiency (in vitro). Can catalyze the...  more1Details
40S ribosomal protein S19Plasmodium falciparum (isolate 3D7)Not Available1Details
40S ribosomal protein S21Plasmodium falciparum (isolate 3D7)Not Available1Details
40S ribosomal protein S3Plasmodium falciparum (isolate 3D7)Not Available1Details
40S ribosomal protein S5, putativePlasmodium falciparum (isolate 3D7)Not Available1Details
45 kDa immediate-early protein 2Human cytomegalovirus (strain Towne)Activates the E1.7 promoter. This activation is augmented by the IE1 protein. It down-regulates the transcription of ...  more1Details
5'(3')-deoxyribonucleotidase, cytosolic typeHumansDephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides, with a preference for dUMP (Ref.12). Also deph...  more1Details
5'(3')-deoxyribonucleotidase, mitochondrialHumansDephosphorylates preferentially the 5'- and 2'(3')-phosphates of uracil and thymine (deoxy)ribonucleotide monophospha...  more2Details
5'-AMP-activated protein kinaseRatNot Available5Details
5'-AMP-activated protein kinaseHumansNot Available19Details
5'-AMP-activated protein kinase catalytic subunit alpha-1HumansCatalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in re...  more9Details
5'-AMP-activated protein kinase subunit beta-1HumansNon-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role i...  more9Details
5'-AMP-activated protein kinase subunit gamma-1HumansAMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role...  more6Details
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidaseEscherichia coli (strain K12)Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocys...  more5Details
Displaying targets 151 - 175 of 6103 in total