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Displaying targets 251 - 275 of 6103 in total
TargetOrganismDescription# of Drugs
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrialHumansInhibits pyruvate dehydrogenase activity by phosphorylation of the E1 subunit PDHA1, and thereby regulates glucose me...  more5Details
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrialHumansKinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation o...  more4Details
A disintegrin and metalloproteinase with thrombospondin motifs 13HumansCleaves the vWF multimers in plasma into smaller forms thereby controlling vWF-mediated platelet thrombus formation4Details
A disintegrin and metalloproteinase with thrombospondin motifs 4HumansCleaves aggrecan, a cartilage proteoglycan, at the '392-Glu-|-Ala-393' site and may be involved in its turnover. Also...  more3Details
A disintegrin and metalloproteinase with thrombospondin motifs 5HumansMetalloproteinase that plays an important role in connective tissue organization, development, inflammation and cell ...  more6Details
A-type voltage-gated potassium channel KCND1HumansA-type voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes in the ...  more1Details
A-type voltage-gated potassium channel KCND2HumansVoltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in ...  more3Details
A-type voltage-gated potassium channel KCND3HumansPore-forming (alpha) subunit of voltage-gated A-type potassium channels that mediates transmembrane potassium transpo...  more11Details
Aac(6')-Ii proteinEnterococcus faeciumNot Available2Details
ABC multidrug transporter MDR2Trichophyton interdigitale (strain MR816)Pleiotropic ABC efflux transporter that may be involved in the modulation susceptibility to a wide range of unrelated...  more1Details
ABC transporter, periplasmic substrate-binding proteinRuegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3)Not Available1Details
ABC transportersOnchocerca volvulusNot Available1Details
ABM domain-containing proteinBacillus cereus (strain ATCC 14579 / DSM 31)Not Available1Details
Acetolactate synthase, catabolicKlebsiella pneumoniaeNot Available5Details
Acetyl transferaseSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)Not Available2Details
Acetyl-CoA acetyltransferaseZoogloea ramigeraNot Available8Details
Acetyl-CoA acetyltransferase, cytosolicHumansInvolved in the biosynthetic pathway of cholesterol2Details
Acetyl-CoA acetyltransferase, mitochondrialHumansThis is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic proce...  more5Details
Acetyl-CoA carboxylase 1HumansCytosolic enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the first and rate-limiting step of d...  more5Details
Acetyl-CoA carboxylase 2HumansMitochondrial enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA and plays a central role in fatty ...  more11Details
Acetyl-coenzyme A synthetaseSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic an...  more2Details
Acetyl-coenzyme A synthetase 2-like, mitochondrialHumansCatalyzes the synthesis of acetyl-CoA from short-chain fatty acids. Acetate is the preferred substrate. Can also util...  more1Details
Acetyl-coenzyme A synthetase, cytoplasmicHumansCatalyzes the synthesis of acetyl-CoA from short-chain fatty acids. Acetate is the preferred substrate. Can also util...  more4Details
Acetylcholine receptor subunit alphaHumansUpon acetylcholine binding, the AChR responds by an extensive change in conformation that affects all subunits and le...  more4Details
Acetylcholine receptor subunit alpha-type acr-16Caenorhabditis elegansAfter binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and l...  more2Details
Displaying targets 251 - 275 of 6103 in total