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Displaying targets 51 - 75 of 6103 in total
TargetOrganismDescription# of Drugs
2,5-diketo-D-gluconic acid reductase ACorynebacterium sp. (strain ATCC 31090)Catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG). 5-keto-D-fructose and ...  more1Details
2-amino-3-ketobutyrate coenzyme A ligaseEscherichia coli (strain K12)Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.1Details
2-amino-3-ketobutyrate coenzyme A ligase, mitochondrialHumansPyridoxal phosphate (PLP) dependent enzyme, which catalyzes the cleavage of 2-amino-3-oxobutanoate to glycine and ace...  more2Details
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinaseEscherichia coli (strain K12)Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an en...  more7Details
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinaseHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an en...  more1Details
2-aminobenzoylacetyl-CoA thioesterasePseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)Required for the biosynthesis of the quorum-sensing signaling molecules 2-heptyl-4(1H)-quinolone (HHQ) and 2-heptyl-3...  more1Details
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthaseShigella flexneriInvolved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major buildi...  more6Details
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthaseShewanella oneidensis (strain MR-1)Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major buildi...  more1Details
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthaseMycobacterium smegmatis (strain ATCC 700084 / mc(2)155)Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major buildi...  more1Details
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthaseThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major buildi...  more2Details
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthaseEscherichia coli (strain K12)Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major buildi...  more1Details
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferaseEscherichia coli (strain K12)Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphat...  more3Details
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferaseThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphat...  more1Details
2-Cys peroxiredoxinPlasmodium falciparum (isolate 3D7)Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and a...  more1Details
2-dehydro-3-deoxyphosphooctonate aldolaseAquifex aeolicus (strain VF5)Not Available8Details
2-dehydro-3-deoxyphosphooctonate aldolaseShigella flexneriNot Available4Details
2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolaseBurkholderia xenovorans (strain LB400)Catalyzes an unusual C-C bond hydrolysis of 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid (HOPDA) to produce benzoic ...  more4Details
2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolasePseudomonas fluorescensNot Available7Details
2-Hydroxyacid oxidase 1HumansBroad substrate specificity (S)-2-hydroxy-acid oxidase that preferentially oxidizes glycolate. The glyoxylate produce...  more11Details
2-Hydroxyacid oxidase 2HumansOxidase that catalyzes the oxidation of medium and long chain hydroxyacids such as 2-hydroxyhexadecanoate and 2-hydro...  more2Details
2-hydroxyacylsphingosine 1-beta-galactosyltransferaseHumansCatalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, whi...  more1Details
2-hydroxychromene-2-carboxylate isomerasePseudomonas putidaInvolved in the naphthalene catabolic pathway. Catalyzes the reversible glutathione-dependent isomerization of 2-hydr...  more3Details
2-hydroxymuconate tautomerasePseudomonas putidaCatalyzes the ketonization of 2-hydroxymuconate stereoselectively to yield 2-oxo-3-hexenedioate.1Details
2-iminobutanoate/2-iminopropanoate deaminaseEscherichia coli (strain K12)Accelerates the release of ammonia from reactive enamine/imine intermediates of the PLP-dependent threonine dehydrata...  more1Details
2-isopropylmalate synthaseMycobacterium tuberculosisCatalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (alpha-ketoisovalerate) to ...  more1Details
Displaying targets 51 - 75 of 6103 in total