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Displaying targets 101 - 125 of 6103 in total
TargetOrganismDescription# of Drugs
3-dehydroquinate dehydrataseStreptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)Catalyzes a trans-dehydration via an enolate intermediate.5Details
3-dehydroquinate dehydrataseHelicobacter pylori (strain ATCC 700392 / 26695)Catalyzes a trans-dehydration via an enolate intermediate.2Details
3-dehydroquinate dehydrataseMycobacterium tuberculosisCatalyzes a trans-dehydration via an enolate intermediate.2Details
3-dehydroquinate dehydrataseSalmonella typhiInvolved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Cataly...  more1Details
3-dehydroquinate synthaseStaphylococcus aureus (strain MRSA252)Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).1Details
3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsCHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) ...  more1Details
3-deoxy-manno-octulosonate cytidylyltransferaseEscherichia coliActivates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.5Details
3-deoxy-manno-octulosonate cytidylyltransferaseHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.1Details
3-hydroxy-3-methylglutaryl-coenzyme A reductasePseudomonas mevaloniiP.mevalonii can use mevalonate as sole carbon source. With this enzyme mevalonate is deacetylated to HMG-CoA.4Details
3-hydroxy-3-methylglutaryl-coenzyme A reductaseHumansCatalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in ...  more33Details
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZHelicobacter pyloriInvolved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and ...  more10Details
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZHelicobacter pylori (strain ATCC 700392 / 26695)Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and ...  more1Details
3-hydroxyacyl-CoA dehydrogenase type-2HumansMitochondrial dehydrogenase involved in pathways of fatty acid, branched-chain amino acid and steroid metabolism. Act...  more5Details
3-hydroxyanthranilate 3,4-dioxygenaseRalstonia metallidurans (strain CH34 / ATCC 43123 / DSM 2839)Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which sponta...  more1Details
3-hydroxydecanoyl-[acyl-carrier-protein] dehydrataseShigella flexneriNecessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecan...  more1Details
3-hydroxydecanoyl-[acyl-carrier-protein] dehydrataseEscherichia coli (strain K12)Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecan...  more1Details
3-hydroxyisobutyrate dehydrogenase, mitochondrialHumansNot Available1Details
3-hydroxyisobutyryl-CoA hydrolase, mitochondrialHumansHydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could b...  more1Details
3-isopropylmalate dehydrogenaseThiobacillus ferrooxidansCatalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopent...  more1Details
3-keto-L-gulonate-6-phosphate decarboxylase UlaDEscherichia coli (strain K12)Catalyzes the decarboxylation of 3-keto-L-gulonate-6-P into L-xylulose-5-P. Is involved in the anaerobic L-ascorbate ...  more5Details
3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7HumansBifunctional enzyme involved in steroid-hormone metabolism and cholesterol biosynthesis. Catalyzes the NADP(H)-depend...  more1Details
3-ketoacyl-CoA thiolasePseudomonas fragiCatalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid tw...  more1Details
3-ketoacyl-CoA thiolase, mitochondrialHumansIn the production of energy from fats, this is one of the enzymes that catalyzes the last step of the mitochondrial b...  more1Details
3-mercaptopyruvate sulfurtransferaseEscherichia coli (strain K12)Catalyzes the transfer of sulfur from 3-mercaptopyruvate to a thiol-containing acceptor to form an intramolecular dis...  more1Details
3-mercaptopyruvate sulfurtransferaseHumansTransfer of a sulfur ion to cyanide or to other thiol compounds. Also has weak rhodanese activity. Detoxifies cyanide...  more2Details
Displaying targets 101 - 125 of 6103 in total