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Displaying drugs 276 - 300 of 6215 in total
Humanized monoclonal antibody (IgG1k) produced by recombinant DNA technology, directed to an epitope in the A antigenic site of the F protein of respiratory syncytial virus (RSV). Synagis is a composite of human (95%) and murine (5%) antibody sequences. The human heavy chain sequence was derived from the constant domains...
Approved
Investigational
Matched Description: … 2% carbohydrate by weight and has a molecular weight of 147.7 kDa +/- 1 kDa (MALDI-TOF) ... and Cess (2). ... antigenic site of the F protein of respiratory syncytial virus (RSV). …
Matched Categories: … Respiratory Syncytial Virus Anti-F Protein Monoclonal Antibody …
Matched Products: … SYNAGIS 100 MG/1 ML IM ENJEKSIYONLUK ÇÖZELTI IÇEREN FLAKON,1 ADET ... SYNAGIS 100 MG/1 ML IM ENJEKSIYONLUK ÇÖZELTI IÇEREN FLAKON, 1 ADET ... SYNAGIS 100 ML IM ENJEKSIYONLUK ÇÖZELTI IÇEREN FLAKON,1 ADET …
Infection with pathogenic filoviruses, such as Zaire ebolavirus (Ebola virus, EBOV), can cause severe hemorrhagic fever in humans, resulting in frequent outbreaks with case fatality rates as high as 90%.[A225933, A225938] Virtually all steps of the EBOV lifecycle have been targeted for therapeutic development. However, to date, the most successful...
Approved
Investigational
Matched Description: … virus disease (EVD) in the Democratic Republic of Congo during a previous outbreak that began in 2018 ... EBOV outbreak 11 years after infection, which displays strong glycan-independent binding to a conserved ... Infection with pathogenic filoviruses, such as _Zaire ebolavirus_ (Ebola virus, EBOV), can cause severe …
Matched Categories: … Treatments for Ebola Virus Disease …
Berotralstat is a selective inhibitor of plasma kallikrein used in the prophylaxis of attacks of hereditary angioedema (HAE). It works by blocking the enzymatic activity of plasma kallikrein in releasing bradykinin, the major biologic peptide that promotes swelling and pain associated with attacks of HAE. Berotralstat is strictly used to...
Approved
Matched Synonyms: … (+)-1-(3-(aminomethyl) phenyl)-N-(5-((3-cyanophenyl)(cyclopropylmethylamino)methyl)-2-fluorophenyl)-3 ... (R)-1-(3-(aminomethyl) phenyl)-N-(5-((3- cyanophenyl)(cyclopropylmethylamino)methyl)-2-fluorophenyl)- ... 2-[3-(aminomethyl)phenyl]-N-[5-[(R)-(3-cyanophenyl)-(cyclopropylmethylamino)methyl]-2-fluorophenyl]-5 …
Matched Iupac: … 1-[3-(aminomethyl)phenyl]-N-{5-[(R)-(3-cyanophenyl)[(cyclopropylmethyl)amino]methyl]-2-fluorophenyl}- ... 3-(trifluoromethyl)-1H-pyrazole-5-carboxamide …
Matched Description: … Berotralstat is a selective inhibitor of plasma kallikrein used in the prophylaxis of attacks of hereditary ... [A225106] Berotralstat was first approved by the FDA on December 3, 2020, as the first once-daily oral …
Matched Salts cas: … 1809010-52-3
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Pantethine is a naturally occurring compound synthesized in the body from pantothenic acid (vitamin B5) via addition of cysteamine. It consists of two molecules of pantetheine that form a dimer via disufide linkages, and acts as an intermediate in the production of Coenzyme A. Coenzyme A plays an essential role...
Approved
Investigational
Matched Synonyms: … D-Bis(N-pantothenyl-beta-aminoethyl) disulfide …
Matched Iupac: … (2R)-N-[2-({2-[(2-{3-[(2R)-2,4-dihydroxy-3,3-dimethylbutanamido]propanamido}ethyl)disulfanyl]ethyl}carbamoyl …
Matched Description: … in the production of Coenzyme A. ... Coenzyme A plays an essential role as a cofactor in the metabolism of lipids and carbohydrates including ... Pantethine is a naturally occurring compound synthesized in the body from pantothenic acid (vitamin B5 …
Matched Categories: … Vitamin B Complex …
Trypan blue is a diazo dye used in ophthalmic cataract surgery to stain the anterior capsule in the presence of a mature cataract. This is done to aid in visualization before creating the continuous curvilinear capsulorhexis.
Approved
Matched Iupac: … 5-amino-3-[(E)-2-{4'-[(E)-2-(8-amino-1-hydroxy-3,6-disulfonaphthalen-2-yl)diazen-1-yl]-3,3'-dimethyl- ... [1,1'-biphenyl]-4-yl}diazen-1-yl]-4-hydroxynaphthalene-2,7-disulfonic acid …
Matched Description: … of a mature cataract. ... Trypan blue is a diazo dye used in ophthalmic cataract surgery to stain the anterior capsule in the presence …
Matched Salts cas: … 72-57-1
Matched Categories: … Compounds used in a research, industrial, or household setting …
Tetracycline is a broad spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria. It exerts a bacteriostatic effect on bacteria by binding reversible to the bacterial 30S ribosomal subunit and blocking incoming aminoacyl tRNA from binding to the ribosome acceptor site. It also binds to some extent to the...
Approved
Vet approved
Withdrawn
Matched Synonyms: … 12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2- …
Matched Iupac: … dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2- …
Matched Description: … Tetracycline is a broad spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria ... It exerts a bacteriostatic effect on bacteria by binding reversible to the bacterial 30S ribosomal subunit ... for the use of all liquid oral drug products formulated for pediatric use containing tetracycline in a
Matched Products: … Tetracycline 3 percent a First Aid Antibiotic ... Achromycin Ont Oph 1% ... Tetracycline 1% Ophthalmic Ointment …
Baricitinib is a Janus kinase (JAK) inhibitor. JAKs are tyrosine protein kinases that play an important role in pro-inflammatory signaling pathways. Overactive JAKs have been implicated in autoimmune disorders, such as rheumatoid arthritis. By inhibiting the actions of JAK1 and JAK2, baricitinib attenuates JAK-mediated inflammation and immune responses. Baricitinib was...
Approved
Investigational
Matched Iupac: … 2-[1-(ethanesulfonyl)-3-(4-{7H-pyrrolo[2,3-d]pyrimidin-4-yl}-1H-pyrazol-1-yl)azetidin-3-yl]acetonitrile …
Matched Description: … Baricitinib is a Janus kinase (JAK) inhibitor. ... for the treatment of rheumatoid arthritis in adults [A248395] and was later approved by the FDA in 2018 ... [A248405] While baricitinib was granted emergency use as a treatment for COVID-19 in combination with …
Matched Categories: … MATE 2 Substrates with a Narrow Therapeutic Index ... Heterocyclic Compounds, 1-Ring ... MATE 2 Inhibitors ... MATE 2 Substrates ... Heterocyclic Compounds, 2-Ring …
Matched Products: … โอลูเมียนท์ (2 มก.) ... UNAMİTY 2 MG FİLM KAPLI TABLET, 7 ADET ... UNAMİTY 2 MG FİLM KAPLI TABLET, 28 ADET …
Becaplermin is produced by recombinant DNA technology by insertion of the gene for the B chain of platelet derived growth factor (PDGF) into the yeast, Saccharomyces cerevisiae. Becaplermin has a molecular weight of approximately 25 KD and is a homodimer composed of two identical polypeptide chains that are bound together...
Approved
Investigational
Matched Synonyms: … PDGF-2
Matched Description: … Becaplermin has a molecular weight of approximately 25 KD and is a homodimer composed of two identical ... Becaplermin is produced by recombinant DNA technology by insertion of the gene for the B chain of platelet …
Naproxen is classified as a nonsteroidal anti-inflammatory dug (NSAID) and was initially approved for prescription use in 1976 and then for over-the-counter (OTC) use in 1994. It can effectively manage acute pain as well as pain related to rheumatic diseases, and has a well studied adverse effect profile. Given its...
Approved
Vet approved
Matched International brands: … Bumaflex N
Matched Synonyms: … (+)-2-(6-Methoxy-2-naphthyl)propionic acid ... (+)-2-(Methoxy-2-naphthyl)-propionsäure ... (+)-2-(Methoxy-2-naphthyl)-propionic acid …
Matched Iupac: … (2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid …
Matched Description: … for a variety of clinical situations requiring analgesia. ... Naproxen is classified as a nonsteroidal anti-inflammatory dug (NSAID) and was initially approved for ... A178975] It can effectively manage acute pain as well as pain related to rheumatic diseases, and has a
Matched Salts cas: … 26159-34-2
Matched Categories: … Non COX-2 selective NSAIDS …
Matched Products: … NAPROXENO 3 % ... NAPROXENO SUSPENSION 3% ... A-NOX FORT 550 MG TABLET, 20 ADET …
A benzimidazole broad-spectrum anthelmintic structurally related to mebendazole that is effective against many diseases. (From Martindale, The Extra Pharmacopoeia, 30th ed, p38)
Approved
Vet approved
Matched International brands: … Ben-A
Matched Synonyms: … O-methyl N-(5-(propylthio)-2-benzimidazolyl)carbamate ... 5-(propylthio)-2-carbomethoxyaminobenzimidazole ... (5-(propylthio)-1H-benzimidazol-2-yl)carbamic acid methyl ester …
Matched Iupac: … methyl N-[6-(propylsulfanyl)-1H-1,3-benzodiazol-2-yl]carbamate …
Matched Description: … A benzimidazole broad-spectrum anthelmintic structurally related to mebendazole that is effective against …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … A-zole Suspension (Strawberry) 200mg/5ml ... ANDAZOL 400 MG FILM KAPLI TABLET, 1 ADET ... HELMADOL 400 MG FİLM KAPLI TABLET, 3 ADET …
Approved
Experimental
Matched Mixtures name: … Le 100 B
Antilipemic agent that lowers cholesterol and triglycerides. It decreases low density lipoproteins and increases high density lipoproteins.
Approved
Investigational
Matched Synonyms: … 2-(p-(2-(p-Chlorobenzamido)ethyl)phenoxy)-2-methylpropionic acid …
Matched Iupac: … 2-(4-{2-[(4-chlorophenyl)formamido]ethyl}phenoxy)-2-methylpropanoic acid …
Bilastine is a novel new-generation antihistamine that is highly selective for the H1 histamine receptor, has a rapid onset and prolonged duration of action.
Approved
Investigational
Matched Iupac: … 2-[4-(2-{4-[1-(2-ethoxyethyl)-1H-1,3-benzodiazol-2-yl]piperidin-1-yl}ethyl)phenyl]-2-methylpropanoic …
Matched Description: … , has a rapid onset and prolonged duration of action. ... Bilastine is a novel new-generation antihistamine that is highly selective for the H1 histamine receptor …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Ibrutinib is a small molecule that acts as an irreversible potent inhibitor of Burton's tyrosine kinase. It is designated as a targeted covalent drug and presented as a promising activity in B-cell malignancies in clinical trials. Ibrutinib was developed by Pharmacyclics Inc and was first approved by the FDA in...
Approved
Matched Synonyms: … 1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one …
Matched Iupac: … 1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one …
Matched Description: … It is designated as a targeted covalent drug and presented as a promising activity in B-cell malignancies ... Ibrutinib is a small molecule that acts as an irreversible potent inhibitor of Burton's tyrosine kinase …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Remimazolam is an ultra short-acting benzodiazepine used in the induction and maintenance of sedation during short (<30 minute) procedures. Recent trends in anesthesia-related drug development have touted the benefits of so-called "soft drugs" - these agents, such as remifentanil, are designed to be metabolically fragile and thus susceptible to rapid...
Approved
Investigational
Matched Iupac: … methyl 3-[(7S)-12-bromo-3-methyl-9-(pyridin-2-yl)-2,5,8-triazatricyclo[8.4.0.0^{2,6}]tetradeca-1(14), …
Matched Description: … [A214857] These "soft drugs" are useful in the context of surgical procedures, wherein a rapid onset/ …
Matched Salts cas: … 1001415-66-2
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor...
Approved
Investigational
Matched Description: … It is a naturally occurring anticoagulant released from mast cells. ... Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers ... infusions; activated partial prothrombin time (aPTT) monitoring is required when using UH; and UH has a
Matched Mixtures name: … BARICUS 50 IU/%1/%10 JEL , 50 G …
Matched Products: … THROMBOCUTAN 30000IE GEL N ... THROMBOCUTAN 30000IE SAL N ... B. BRAUN HEPARINISED SALINE 10IU/ML SOLUTION FOR INJECTION …
Miglustat, commonly marketed under the trade name Zavesca, is a drug used to treat Gaucher disease. It inhibits the enzyme glucosylceramide synthase, an essential enzyme for the synthesis of most glycosphingolipids. It is only used for patients who cannot be treated with enzyme replacement therapy with imiglucerase. Miglustat is now...
Approved
Matched Synonyms: … N-butyl-1-deoxynojirimycin ... N-(n-Butyl)deoxynojirimycin ... N-Butylmoranoline …
Matched Iupac: … (2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-3,4,5-triol …
Matched Description: … Miglustat, commonly marketed under the trade name Zavesca, is a drug used to treat Gaucher disease. ... with miglustat showed that therapeutic levels of the drug could not be achieved in patients without a
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Human varicella-zoster immune globulin is a solvent/detergent-treated sterile liquid preparation of purified human immune globulin G (IgG) containing antibodies to varicella zoster virus (anti-VZV). It is prepared from pools of healthy human donors' plasma via anion-exchange column chromatography and was approved in 2012 under the name VariZIG to reduce the...
Approved
Matched Synonyms: … Human herpesvirus 3 immune globulin …
Matched Description: … Human varicella-zoster immune globulin is a solvent/detergent-treated sterile liquid preparation of purified ... human immune globulin G (IgG) containing antibodies to varicella zoster virus (anti-VZV). ... The therapeutic efficacy is proven if administered within 4 days of exposure to varicella zoster virus
There is a great deal of evidence indicating that vascular endothelial growth factor (VEGF) is important for the survival and proliferation of cancer cells.[A192939,A192837,A192891,A193275] VEGF plays an important role in angiogenesis, lymphangiogenesis, and tumor growth, which are all factors that contribute to its attractiveness as a therapeutic target for anti-cancer...
Approved
Investigational
Matched Description: … neutralizing VEGF-A. ... There is a great deal of evidence indicating that vascular endothelial growth factor (VEGF) is important ... lymphangiogenesis, and tumor growth, which are all factors that contribute to its attractiveness as a
Matched Products: … ZİRABEV 100 MG/4 ML İNFÜZYONLUK ÇÖZELTİ, 1 ADET ... ZİRABEV 400 MG/16 ML İNFÜZYONLUK ÇÖZELTİ, 1 ADET ... ALTUZAN 100MG/4ML KONSANTRE INFÜZYON COZELTİSİ, 1 ADET …
Potassium bicarbonate is a white, crystalline, slightly alkaline and salty substance. It is produced by the passage of carbon dioxide through an aqueous potassium carbonate solution. It is used in medicine as an antacid. It is registered in the FDA under the section of suitable, safe and effective ingredients for...
Approved
Matched Description: … Potassium bicarbonate is a white, crystalline, slightly alkaline and salty substance. ... [L1836] This FDA denomination classifies potassium bicarbonate as a GRAS ingredient.[L1837] …
Matched Mixtures name: … Isotonix Vitamin B-folic Acid-mineral Supple ... Isotonix Advanced B-complex Vitamins With Potassium and Magnesium …
Ertapenem is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics. It was first authorized for use in the US in November 2001 and in Europe in April 2002. Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic bacteria, ertapenem is used to...
Approved
Investigational
Matched Synonyms: … (1R,5S,6S,8R,2'S,4'S)-2-(2-(3-carboxyphenylcarbamoyl)pyrrolidin-4-ylthio)-6-(1-hydroxyethyl)-1-methylcarbapenem ... -7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid ... (4R,5S,6S)-3-((3S,5S)-5-((3-carboxyphenyl)carbamoyl)pyrrolidin-3-ylthio)-6-((R)-1-hydroxyethyl)-4-methyl …
Matched Iupac: … ]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid ... (4R,5S,6S)-3-{[(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl …
Matched Description: … Ertapenem is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics. ... [A447] Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic …
Matched Salts cas: … 153773-82-1
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … ERTAPENEM 1G/VIAL POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE ... ERTAGRAM® 1 G ... INVANZ 1 G IM/IV ENEJEKSİYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON, 1 ADET …
Propiolactone is a lactone compound with a four-membered ring. It is a colorless liquid with a pungent slightly sweet odor. Propiolactone is a disinfectant used for the sterilization of blood plasma, vaccines, tissue grafts, surgical instruments, and enzymes. It has been used against bacteria, fungi, and virus. It is currently...
Approved
Withdrawn
Matched Synonyms: … 3-propanolide …
Matched Iupac: … oxetan-2-one …
Matched Description: … It has been used against bacteria, fungi, and virus. ... Propiolactone is a lactone compound with a four-membered ring. ... It is a colorless liquid with a pungent slightly sweet odor. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Zoledronic acid, or CGP 42'446, is a third generation, nitrogen containing bisphosphonate similar to ibandronic acid, minodronic acid, and risedronic acid. Zoledronic acid is used to treat and prevent multiple forms of osteoporosis, hypercalcemia of malignancy, multiple myeloma, bone metastases from solid tumors, and Paget’s disease of bone.[L13712,L13715,L13721] Zoledronic acid...
Approved
Matched Synonyms: … (1-hydroxy-2-imidazol-1-ylethylidene)diphosphonic acid ... (1-hydroxy-2-(1H-imidazol-1-yl)ethylidene)bisphosphonic acid …
Matched Iupac: … [1-hydroxy-2-(1H-imidazol-1-yl)-1-phosphonoethyl]phosphonic acid …
Matched Description: … Zoledronic acid, or CGP 42'446,[A203120] is a third generation, nitrogen containing bisphosphonate similar …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … N/A ... ICIN KON.COZELTI ICEREN KUL.HAZIR SIRINGA, 3 ADET ... Zoledronic Acid - A
Ulobetasol is a highly potent corticosteroid. It is structurally related to clobetasol. Due to its high potency, it is mainly prescribed in the treatment of severe plaque psoriasis and corticosteroid responsive dermatoses.[L15047,L15052,L15102] Ulobetasol was granted FDA approval on 17 December 1990.
Approved
Matched Iupac: … (1R,2S,8S,10S,11S,13S,14R,15S,17S)-14-(2-chloroacetyl)-1,8-difluoro-14,17-dihydroxy-2,13,15-trimethyltetracyclo …
Matched Description: … Ulobetasol is a highly potent corticosteroid.[A215597] It is structurally related to [clobetasol]. …
A corticosteroid used topically in the treatment of various skin disorders. It is usually employed as a cream or an ointment, and is also used as a polyethylene tape with an adhesive. (From Martindale, The Extra Pharmacopoeia, 30th ed, p733)
Approved
Matched Iupac: … (1S,2S,4R,8S,9S,11S,12S,13R,19S)-19-fluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo …
Matched Description: … It is usually employed as a cream or an ointment, and is also used as a polyethylene tape with an adhesive ... A corticosteroid used topically in the treatment of various skin disorders. …
Displaying drugs 276 - 300 of 6215 in total