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Displaying drugs 351 - 375 of 558 in total

Melphalan

Melphalan is a nitrogen mustard or bischloroethylamine type alkylating agent. It was first synthesized in the early 1950s by substituting L-phenylalanine for the methyl group on nitrogen mustard.[A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. It is also used for high-conditioning before hematopoietic stem...
Approved
Matched Description: … [A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. …
Matched Salts name: … Melphalan hydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Melphalan Hydrochloride ... Melphalan hydrochloride …

Cyclobenzaprine

Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961 and has been available for human use since 1977. It was initially studied for use as antidepressant given its structural similarity to tricyclic antidepressants - it differs from Amitriptyline by only a single double bond.[A185039,A184982] Since its approval, it has...
Approved
Matched Description: … Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961[A185039] and has been …
Matched Salts name: … Cyclobenzaprine hydrochloride …
Matched Products: … Cyclobenzaprine Hydrochloride ... Cyclobenzaprine hydrochloride …

Naftifine

Naftifine is a synthetic, broad spectrum, antifungal agent and allylamine derivative for the topical treatment of tinea pedis, tinea cruris, and tinea corporis caused by the organisms Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans and Epidermophyton floccosum.
Approved
Matched Description: … , Trichophyton mentagrophytes, Trichophyton tonsurans and Epidermophyton floccosum. ... Naftifine is a synthetic, broad spectrum, antifungal agent and allylamine derivative for the topical ... treatment of tinea pedis, tinea cruris, and tinea corporis caused by the organisms Trichophyton rubrum …
Matched Salts name: … Naftifine Hydrochloride …
Matched Products: … Naftifine Hydrochloride ... Naftifine hydrochloride …

Ticlopidine

Ticlopidine is an effective inhibitor of platelet aggregation. It is a prodrug that is metabolised to an active form, which blocks the ADP receptor that is involved in GPIIb/IIIa receptor activation leading to platelet aggregation. Ticlopidine is marketed under the brand name Ticlid and is indicated for patients who cannot...
Approved
Matched Description: … Ticlopidine is marketed under the brand name Ticlid and is indicated for patients who cannot take aspirin ... includes a black-box warning of neutropenia, aplastic anemia, thrombotic thrombocytopenia purpura, and ... agranulocytosis, so it is necessary to monitor patients' WBC and platelets when they are taking ticlopidine …
Matched Salts name: … Ticlopidine hydrochloride …
Matched Categories: … Blood and Blood Forming Organs ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … Ticlopidine Hydrochloride ... Ticlopidine hydrochloride …

Arginine

An essential amino acid that is physiologically active in the L-form.
Investigational
Nutraceutical
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose …
Matched Salts name: … Arginine hydrochloride …
Matched Categories: … arginine hydrochloride ... arginine and lysine ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... Blood Substitutes and Perfusion Solutions …
Matched Products: … L-arginine Hydrochloride Injection …

Glyceryl monostearate

Glycerol monostearate, commonly known as GMS, is the glycerol ester of stearic acid . It is commonly used as an emulsifier in foods.
Experimental
Matched Synonyms: … Geleol mono and diglycerides …

Lawsonia inermis leaf

Lawsonia inermis leaf is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Plants and Plant Parts, Henna Lawsonia Inermis …

Parecoxib

Parecoxib is a water-soluble and injectable prodrug of valdecoxib. It is marketed as Dynastat in the European Union. Parecoxib is a COX2 selective inhibitor in the same category as celecoxib (Celebrex) and rofecoxib (Vioxx). As it is injectable, it can be used perioperatively when patients are unable to take oral...
Approved
Matched Description: … Parecoxib is a water-soluble and injectable prodrug of valdecoxib. ... Parecoxib is a COX2 selective inhibitor in the same category as celecoxib (Celebrex) and rofecoxib (Vioxx …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Dynastat Powder and Solvent for Solution for Injection 40mg …

Chlorine dioxide

Chlorine Dioxide has been used in trials studying the treatment of Halitosis.
Investigational
Matched Products: … Disinfectant and Sanitizer …

Carteolol

A beta-adrenergic antagonist used as an anti-arrhythmia agent, an anti-angina agent, an antihypertensive agent, and an antiglaucoma agent.
Approved
Matched Description: … beta-adrenergic antagonist used as an anti-arrhythmia agent, an anti-angina agent, an antihypertensive agent, and …
Matched Salts name: … Carteolol hydrochloride …
Matched Categories: … Antiglaucoma Preparations and Miotics …
Matched Products: … Carteolol Hydrochloride …

Dexrazoxane

An antimitotic agent with immunosuppressive properties. Dexrazoxane, the (+)-enantiomorph of razoxane, provides cardioprotection against anthracycline toxicity. It appears to inhibit formation of a toxic iron-anthracycline complex. [PubChem] The Food and Drug Administration has designated dexrazoxane as an orphan drug for use in the prevention or reduction in the incidence and...
Approved
Withdrawn
Matched Description: … prevention or reduction in the incidence and severity of anthracycline-induced cardiomyopathy. ... [PubChem] The Food and Drug Administration has designated dexrazoxane as an orphan drug for use in the …
Matched Salts name: … Dexrazoxane hydrochloride …
Matched Products: … Dexrazoxane Hydrochloride …

Naproxen

Naproxen is classified as a nonsteroidal anti-inflammatory dug (NSAID) and was initially approved for prescription use in 1976 and then for over-the-counter (OTC) use in 1994. It can effectively manage acute pain as well as pain related to rheumatic diseases, and has a well studied adverse effect profile. Given its...
Approved
Vet approved
Matched Description: … prescription use in 1976 and then for over-the-counter (OTC) use in 1994. ... Naproxen is classified as a nonsteroidal anti-inflammatory dug (NSAID) and was initially approved for ... [A178975] It can effectively manage acute pain as well as pain related to rheumatic diseases, and has …
Matched Mixtures name: … Naproxen Sodium and Diphenhydramine Hydrochloride ... Naproxen Sodium and Pseudoephedrine Hydrochloride Sinus and Cold ... Naproxen Sodium and Pseudoephedrine Hydrochloride Sinus and Headache …
Matched Categories: … naproxen and misoprostol ... sumatriptan and naproxen ... naproxen and esomeprazole ... naproxen and diphenhydramine ... Genito Urinary System and Sex Hormones …
Matched Products: … Back and Muscle Pain ... Up and Up Naproxen sodium ... Pain and Fever Relief …

Povidone-iodine

Povidone-iodine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine. It contains from 9.0% to 12.0% available iodine, calculated on a dry basis. This unique complex was discovered in 1955 at the Industrial Toxicology Laboratories in Philadelphia by H. A. Shelanski and M. V. Shelanski. During in...
Approved
Matched Description: … Shelanski and M. V. Shelanski. ... Povidone-iodine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine ... Povidone-iodine was immediately marketed, and has since become the universally preferred iodine antiseptic …
Matched Mixtures name: … Physician EZ Use Joint Tunnel and Trigger Kit ... JTT Physicians Joint, Tunnel and Trigger ... BRAUNODERM (IN 250ML AND 1000ML PLASTIC) …
Matched Categories: … Antiseptics and Disinfectants ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Fresh and Pure ... 3M Skin and Nasal Antiseptic ... BETADINE GARGLE AND MOUTH WASH …

Sertraline

Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as Citalopram and Fluoxetine. Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects. Several weeks of therapy with sertraline may be required before...
Approved
Matched Description: … is similar to drugs such as [Citalopram] and [Fluoxetine]. ... popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and ... classes of antidepressants, which frequently cause high levels of drowsiness, dizziness, blurred vision, and …
Matched Salts name: … Sertraline hydrochloride …
Matched Products: … Sertraline Hydrochloride ... Sertraline hydrochloride ... SERTRAline Hydrochloride …

Tolnaftate

Tolnaftate is a synthetic over-the-counter anti-fungal agent. It may come as a cream, powder, spray, or liquid aerosol, and is used to treat jock itch, athlete's foot and ringworm. It is sold under several brand names, most notably Tinactin and Odor Eaters.
Approved
Investigational
Vet approved
Matched Description: … and ringworm. ... It is sold under several brand names, most notably Tinactin and Odor Eaters. ... It may come as a cream, powder, spray, or liquid aerosol, and is used to treat jock itch, athlete's foot …
Matched Mixtures name: … Terbinafine HCl Chlortimazole and Tolnaftate …
Matched Products: … Up and Up Antifungal ... Fungi Nail Toe and Foot ... Up and Up Soothing Antifungal …

Chloroprocaine

Chloroprocaine is an ester local anesthetic commonly available in its salt form, chloroprocaine hydrochloride. Similar to other local anesthetics, it increases the threshold for electrical excitation in nerves by slowing the propagation of the nerve impulse and reducing the rate of rise of the action potential. The pharmacological profile of...
Approved
Investigational
Matched Description: … Chloroprocaine is an ester local anesthetic commonly available in its salt form, chloroprocaine hydrochloride ... [A252952] Chloroprocaine can be given as an injection, and is available in formulations with and without ... formulation can be used for lumbar and caudal epidural blocks. …
Matched Salts name: … Chloroprocaine hydrochloride …
Matched Products: … Chloroprocaine Hydrochloride …

Octinoxate

Octinoxate is a cinnamate ester and common ingredient in sunscreen and other skin care products to minimize DNA photodamage. It was originally developed in 1950's as an organic UV-B filter that absorbs UV-B rays from sun. It is often combined with nanoparticles or other water-resistant liposomes in formulations to increase...
Approved
Investigational
Matched Description: … Octinoxate is a cinnamate ester and common ingredient in sunscreen and other skin care products to minimize ... Its use in pharmaceutical and cosmetic formulations is approved by FDA. ... nanoparticles or other water-resistant liposomes in formulations to increase the localization at the epidermis and …
Matched Mixtures name: … Paul and Joe ... Paul and Joe ... Silk and Shine …
Matched Categories: … Emollients and Protectives …
Matched Products: … Firming and Moisturizing Body ... Clarins Click and Gloss 02 CORAL ... Clarins Click and Gloss 01 VANILLA …

Cyclomethicone 5

Cyclomethicone 5 is member of cyclomethicone, which are a group of liquid methyl siloxanes that have low viscosity and high volatility. Cyclomethicones are cyclic in structure with a monomer backbone of one silicon and two oxygen atoms bonded together. Cyclomethicone 5 is used in cosmetic and personal products as a...
Experimental
Matched Description: … Cyclomethicone 5 is used in cosmetic and personal products as a skin emollient. ... 5 is member of cyclomethicone, which are a group of liquid methyl siloxanes that have low viscosity and ... Cyclomethicones are cyclic in structure with a monomer backbone of one silicon and two oxygen atoms bonded …
Matched Products: … Mefactory Super Clear Lip And Eye Remover …

Hydrocortisone

Hydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex. Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions.[L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named Compound F, or 17-hydroxycorticosterone. Hydrocortisone was granted FDA approval on 5 August 1952.
Approved
Vet approved
Matched Description: … [A188387] Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions. ... [L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named …
Matched Mixtures name: … Neomycin and Polymyxin B Sulfates and Hydrocortisone ... Neomycin and Polymyxin B Sulfates and Hydrocortisone ... Neomycin and Polymyxin B Sulfates and Hydrocortisone …
Matched Categories: … Alimentary Tract and Metabolism ... Sex Hormones and Insulins ... hydrocortisone and mydriatics ... Hydrocortisone and derivatives ... hydrocortisone and antiseptics …
Matched Products: … Rodan and Fields Soothe ... Itch and Rash Cream ... Up and Up Anti Itch …

Sodium fluoride

Sodium fluoride is an inorganic chemical compound that is a source of the fluoride ion in many applications, including dental care and radiographic imaging when it is used as Fluoride ion F-18. Sodium fluoride's benefits on dental health were first observed in the 1930s, when individuals in communities with fluoridated...
Approved
Matched Description: … chemical compound that is a source of the fluoride ion in many applications, including dental care and ... control dental caries is safe when used correctly and is highly effective in reducing the prevalence ... Dental Association (ADA), thorough evidence reviews have indicated that the use of fluoride to prevent and …
Matched Mixtures name: … Nicorette and Aquafresh Fruit Chill and Extreme Clean Whitening ... Twice Science and Wellness Invigorating Wintergreen and Peppermint ... Up and Up Sensitive Toothpaste …
Matched Categories: … Mouthwashes and Gargles ... Alimentary Tract and Metabolism …
Matched Products: … Truly Radiant Whitening and Strengthening Rinse CLEAN AND FRESH ... Fresh Brush and Cover ... Thomas and Friends …

Iron Dextran

Iron dextran is a dark brown, slightly viscous liquid complex of ferric hydroxide and dextran for intravenous or intramuscular use. Iron Dextran is used for the treatment of patients with documented iron deficiency in which oral administration is unsatisfactory or impossible.
Approved
Vet approved
Matched Description: … Iron dextran is a dark brown, slightly viscous liquid complex of ferric hydroxide and dextran for intravenous …
Matched Mixtures name: … Threonate and Succinic Acid ... Iron Aspartate Glycinate and Polysaccharide Complex, Ascorbic Calcium, Vitamin B12, Folic Acid, Calcium …
Matched Products: … Cosmofer 50mg/ml Solution for injection and for infusion …

Benzoyl peroxide

Benzoyl peroxide is a commonly used drug in topical treatments for acne.[L33249,L33264,L33269,L33299,L33314] It has been formulated as products with either a single active ingredient,[L33249,L33299] or with erythromycin, clindamycin, or adapalene. After administration, the peroxide bond is cleaved, allowing benzoyloxy radicals to nonspecifically interact with proteins.[A18903,A233859] This treatment decreases keratin and...
Approved
Matched Description: … [A18903,A233859] This treatment decreases keratin and sebum around follicles, as well as increasing turnover …
Matched Mixtures name: … Clease and Treat ... Clean and Clear Advantage 2-in-1 Acne and Mark Eraser Kit ... Adapalene and Benzoyl Peroxide …
Matched Products: … Acne Face and Body ... Acne Face and Body Wash ... 5% BP Face and Body Wash …

Lurasidone

Lurasidone is an atypical antipsychotic developed by Dainippon Sumitomo Pharma. It was approved by the U.S. Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently pending approval for the treatment of bipolar disorder in the United States.
Approved
Investigational
Matched Description: … Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently …
Matched Salts name: … Lurasidone hydrochloride …
Matched Products: … Lurasidone Hydrochloride ... Lurasidone hydrochloride …

Oxybuprocaine

Oxybuprocaine (also known as Benoxinate) is a local anesthetic, which is used especially in ophthalmology and otolaryngology. Oxybuprocaine binds to sodium channels and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions.
Approved
Investigational
Matched Description: … Oxybuprocaine (also known as Benoxinate) is a local anesthetic, which is used especially in ophthalmology and ... Oxybuprocaine binds to sodium channels and reversibly stabilizes the neuronal membrane which decreases …
Matched Mixtures name: … Fluorescein Sodium and Benoxinate Hydrochloride ... Fluorescein Sodium and Benoxinate Hydrochloride ... Fluorescein Sodium and Benoxinate Hydrochloride …
Matched Salts name: … Oxybuprocaine hydrochloride …
Matched Products: … Minims Benoxinate Hydrochloride 0.4% …

Triptorelin

Triptorelin is a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH). Possessing greater potency than endogenous LHRH, triptorelin reversibly represses gonadotropin secretion. After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production and testicular and ovarian steroidogenesis. Serum testosterone concentrations may fall to levels...
Approved
Vet approved
Matched Description: … and testicular and ovarian steroidogenesis. ... After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production …
Matched Categories: … Hormones and Related Agents ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION 3.75 mg/vial ... POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION 11.25 mg/vial …
Displaying drugs 351 - 375 of 558 in total