Displaying drugs 26 - 50 of 13339 in total
Zolmitriptan
Zolmitriptan is a member of the triptan class of 5-hydroxytryptamine(5-HT)1B/1D/(1F) receptor agonists used to treat acute migraine.[A462, L12978] Sumatriptan was the first triptan to be developed, but had poor oral bioavailability and lipophilicity. This led to the development of second-generation triptans, including almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, and zolmitriptan. Triptans...
Approved
Investigational
Matched Synonyms: … 4-[[3-(2-dimethylaminoethyl)-1H-indol-5-yl]methyl]oxazolidin-2-one ... (S)-4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one …
Matched Iupac: … (4S)-4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one …
Matched Description: … Zolmitriptan is a member of the triptan class of 5-hydroxytryptamine(5-HT)1B/1D/(1F) receptor …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Monoamine Oxidase A Substrates …
Matched Products: … MIGTERA 5 MG FİLM TABLET, 3 ADET ... MIGTERA 2.5 MG FİLM TABLET, 3 ADET ... GRAVIS 5 MG FILM TABLET, 3 TABLET …
Matched Iupac: … (4S)-4-({3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one …
Matched Description: … Zolmitriptan is a member of the triptan class of 5-hydroxytryptamine(5-HT)1B/1D/(1F) receptor …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Monoamine Oxidase A Substrates …
Matched Products: … MIGTERA 5 MG FİLM TABLET, 3 ADET ... MIGTERA 2.5 MG FİLM TABLET, 3 ADET ... GRAVIS 5 MG FILM TABLET, 3 TABLET …
Rutin
A flavonol glycoside found in many plants, including buckwheat; tobacco; forsythia; hydrangea; viola, etc. It has been used therapeutically to decrease capillary fragility.
Approved
Experimental
Investigational
Matched Synonyms: … -4H-1-benzopyran-4-one ... 3-Rutinosyl quercetin ... Quercetin 3-rutinoside …
Matched Iupac: … 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4R,5R,6S)-3,4,5 …
Matched Description: … A flavonol glycoside found in many plants, including buckwheat; tobacco; forsythia; hydrangea; viola, …
Matched Salts cas: … 250249-75-3 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4R,5R,6S)-3,4,5 …
Matched Description: … A flavonol glycoside found in many plants, including buckwheat; tobacco; forsythia; hydrangea; viola, …
Matched Salts cas: … 250249-75-3 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Periciazine
Periciazine is a phenothiazine of the piperidine group. It has been shown to reduce pathologic arousal and affective tension in some psychotic patients, while the symptoms of abnormal mental integration are relatively unaffected. It is a sedative phenothiazine with weak antipsychotic properties. It also has adrenolytic, anticholinergic, metabolic and endocrine...
Approved
Investigational
Matched Synonyms: … Cyano-3 ((hydroxy-4 piperidyl-1)-3 propyl)-10 phenothiazine ... 2-Cyano-10-(3-(4-hydroxy-1-piperidyl)propyl)phenothiazine ... 2-Cyano-10-(3-(4-hydroxypiperidino)propyl)phenothiazine …
Matched Iupac: … 10-[3-(4-hydroxypiperidin-1-yl)propyl]-10H-phenothiazine-2-carbonitrile …
Matched Description: … Periciazine is a phenothiazine of the piperidine group. ... It is a sedative phenothiazine with weak antipsychotic properties. ... phenothiazines, is presumed to act principally in the subcortical areas, by producing what has been described as a …
Matched Categories: … Heterocyclic Compounds, 3-Ring ... Adrenergic alpha-1 Receptor Antagonists …
Matched Iupac: … 10-[3-(4-hydroxypiperidin-1-yl)propyl]-10H-phenothiazine-2-carbonitrile …
Matched Description: … Periciazine is a phenothiazine of the piperidine group. ... It is a sedative phenothiazine with weak antipsychotic properties. ... phenothiazines, is presumed to act principally in the subcortical areas, by producing what has been described as a …
Matched Categories: … Heterocyclic Compounds, 3-Ring ... Adrenergic alpha-1 Receptor Antagonists …
Elvitegravir
Elvitegravir is a human immunodeficiency virus type 1 (HIV-1) integrase strand transfer inhibitor (INSTI) used for the treatment of HIV-1 infection in antiretroviral treatment-experienced adults. Because integrase is necessary for viral replication, inhibition prevents the integration of HIV-1 DNA into the host genome and thereby blocks the formation of the...
Approved
Matched Synonyms: … 6-(3-chloro-2-fluorobenzyl)-1-[(2S)-1-hydroxy-3-methylbutan-2-yl]-7-methoxy-4-oxo-1,4-dihydroquinoline ... -3-carboxylic acid …
Matched Iupac: … 6-[(3-chloro-2-fluorophenyl)methyl]-1-[(2S)-1-hydroxy-3-methylbutan-2-yl]-7-methoxy-4-oxo-1,4-dihydroquinoline ... -3-carboxylic acid …
Matched Description: … Elvitegravir is a human immunodeficiency virus type 1 (HIV-1) integrase strand transfer inhibitor (INSTI ... Although available as a single dose tablet, elvitegravir must be used in combination with an HIV protease ... ) used for the treatment of HIV-1 infection in antiretroviral treatment-experienced adults. …
Matched Iupac: … 6-[(3-chloro-2-fluorophenyl)methyl]-1-[(2S)-1-hydroxy-3-methylbutan-2-yl]-7-methoxy-4-oxo-1,4-dihydroquinoline ... -3-carboxylic acid …
Matched Description: … Elvitegravir is a human immunodeficiency virus type 1 (HIV-1) integrase strand transfer inhibitor (INSTI ... Although available as a single dose tablet, elvitegravir must be used in combination with an HIV protease ... ) used for the treatment of HIV-1 infection in antiretroviral treatment-experienced adults. …
Ivabradine
Ivabradine is a novel heart rate lowering medicine for the symptomatic management of stable angina pectoralis and symptomatic chronic heart failure. Ivabradine, brand name Corlanor, was approved by the FDA in April 2015 for the treatment of chronic heart failure in patients with an ejection fraction of ≤35%, in sinus...
Approved
Matched Synonyms: … 3-[3-({[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}(methyl)amino)propyl]-7,8-dimethoxy ... -2,3,4,5-tetrahydro-1H-3-benzazepin-2-one …
Matched Iupac: … 3-[3-({[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}(methyl)amino)propyl]-7,8-dimethoxy ... -2,3,4,5-tetrahydro-1H-3-benzazepin-2-one …
Matched Description: … Ivabradine is a novel heart rate lowering medicine for the symptomatic management of stable angina pectoralis ... Recently a new indication was added to treat symptomatic heart failure from dilated cardiomyopathy for ... dose-dependent fashion, resulting in a lower heart rate and thus more blood to flow to the myocardium …
Matched Iupac: … 3-[3-({[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}(methyl)amino)propyl]-7,8-dimethoxy ... -2,3,4,5-tetrahydro-1H-3-benzazepin-2-one …
Matched Description: … Ivabradine is a novel heart rate lowering medicine for the symptomatic management of stable angina pectoralis ... Recently a new indication was added to treat symptomatic heart failure from dilated cardiomyopathy for ... dose-dependent fashion, resulting in a lower heart rate and thus more blood to flow to the myocardium …
Pipobroman
An antineoplastic agent that acts by alkylation.
Approved
Matched Synonyms: … 1,4-bis(3-bromopropionyl)piperazine ... N,N-bis-(3-bromopropionyl)-piperazine …
Matched Iupac: … 3-bromo-1-[4-(3-bromopropanoyl)piperazin-1-yl]propan-1-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 3-bromo-1-[4-(3-bromopropanoyl)piperazin-1-yl]propan-1-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Sulfamethoxazole
Sulfamethoxazole is a bacteriostatic sulfonamide antibiotic that interferes with folic acid synthesis in susceptible bacteria. It is generally given in combination with trimethoprim, which inhibits a sequential step in bacterial folic acid synthesis - these agents work synergistically to block two consecutive steps in the biosynthesis of nucleic acids and...
Approved
Matched Synonyms: … 3-Sulfanilamido-5-methylisoxazole ... 3-(p-Aminophenylsulfonamido)-5-methylisoxazole ... 4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfonamide …
Matched Iupac: … 4-amino-N-(5-methyl-1,2-oxazol-3-yl)benzene-1-sulfonamide …
Matched Description: … Sulfamethoxazole is a bacteriostatic sulfonamide antibiotic that interferes with folic acid synthesis ... [L11830] It is generally given in combination with [trimethoprim], which inhibits a sequential step in ... [L11830] In this combination, sulfamethoxazole is useful for the treatment of a variety of bacterial …
Matched Mixtures name: … CO-TRIPIRIM 5 ML 1 AMPUL ... ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPUL, 1 ADET …
Matched Iupac: … 4-amino-N-(5-methyl-1,2-oxazol-3-yl)benzene-1-sulfonamide …
Matched Description: … Sulfamethoxazole is a bacteriostatic sulfonamide antibiotic that interferes with folic acid synthesis ... [L11830] It is generally given in combination with [trimethoprim], which inhibits a sequential step in ... [L11830] In this combination, sulfamethoxazole is useful for the treatment of a variety of bacterial …
Matched Mixtures name: … CO-TRIPIRIM 5 ML 1 AMPUL ... ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPUL, 1 ADET …
Bumetanide
Bumetanide is a sulfamyl diuretic.
Approved
Matched Synonyms: … 3-butylamino-4-(phenoxy)-5-sulfamoylbenzoic acid ... 3-butylamino-4-phenoxy-5-sulfamoyl-benzoic acid ... 3-butylamino-4-phenoxy-5-sulfamoylbenzoic acid …
Matched Iupac: … 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid …
Matched Description: … Bumetanide is a sulfamyl diuretic. …
Matched Mixtures name: … BURINEX TABLET 1 mg ... BURINEX TABLET 1 mg …
Matched Products: … Burinex 1 mg - Tabletten …
Matched Iupac: … 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid …
Matched Description: … Bumetanide is a sulfamyl diuretic. …
Matched Mixtures name: … BURINEX TABLET 1 mg ... BURINEX TABLET 1 mg …
Matched Products: … Burinex 1 mg - Tabletten …
Bortezomib
Bortezomib is a dipeptide boronic acid derivative and proteasome inhibitor used to treat multiple myeloma and mantle cell lymphoma. The 26S proteasome is a protein complex that degrades ubiquitinated proteins in the ubiquitin-proteasome pathway: reversible inhibition of the 26S proteasome, leading to cell cycle arrest and apoptosis of cancer cells,...
Approved
Investigational
Matched Synonyms: … [(1R)-3-methyl-1-({(2S)-3-phenyl-2-[(pyrazin-2-ylcarbonyl)amino]propanoyl}amino)butyl]boronic acid ... N-[(1R)-1-(DIHYDROXYBORYL)-3-methylbutyl]-N-(pyrazin-2-ylcarbonyl)-L-phenylalaninamide …
Matched Iupac: … [(1R)-3-methyl-1-[(2S)-3-phenyl-2-[(pyrazin-2-yl)formamido]propanamido]butyl]boronic acid …
Matched Description: … Bortezomib is a dipeptide boronic acid derivative and proteasome inhibitor used to treat multiple myeloma ... [A204083] The 26S proteasome is a protein complex that degrades ubiquitinated proteins in the ubiquitin-proteasome …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index …
Matched Products: … BORTECADE 1 ... Bortirel 1 mg IV Enjeksiyonluk Çözelti Hazırlamak İçin Toz, 1 ADET ... PORIX® 3.5 POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE …
Matched Iupac: … [(1R)-3-methyl-1-[(2S)-3-phenyl-2-[(pyrazin-2-yl)formamido]propanamido]butyl]boronic acid …
Matched Description: … Bortezomib is a dipeptide boronic acid derivative and proteasome inhibitor used to treat multiple myeloma ... [A204083] The 26S proteasome is a protein complex that degrades ubiquitinated proteins in the ubiquitin-proteasome …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index …
Matched Products: … BORTECADE 1 ... Bortirel 1 mg IV Enjeksiyonluk Çözelti Hazırlamak İçin Toz, 1 ADET ... PORIX® 3.5 POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE …
Methylchloroisothiazolinone
Methylchloroisothiazolinone (MCI) is an isothiazolinone commonly used as a preservative with antibacterial and antifungal properties. It is found within many commercially available cosmetics, lotions, and makeup removers. It is also a known dermatological sensitizer and allergen; some of its side effects include flaky or scaly skin, breakouts, redness or itchiness,...
Approved
Experimental
Matched Synonyms: … 5-Chloro-N-methylisothiazolin-3-one ... 5-Chloro-2-methyl-3(2H)-isothiazolone ... 4-Isothiazolin-3-one, 5-chloro-2-methyl- …
Matched Iupac: … 5-chloro-2-methyl-2,3-dihydro-1,2-thiazol-3-one …
Matched Description: … Sensitivity to Methylchloroisothiazolinone may be identified with a clinical patch test. ... Methylchloroisothiazolinone (MCI) is an isothiazolinone commonly used as a preservative with antibacterial ... It is also a known dermatological sensitizer and allergen; some of its side effects include flaky or …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Compounds used in a research, industrial, or household setting …
Matched Iupac: … 5-chloro-2-methyl-2,3-dihydro-1,2-thiazol-3-one …
Matched Description: … Sensitivity to Methylchloroisothiazolinone may be identified with a clinical patch test. ... Methylchloroisothiazolinone (MCI) is an isothiazolinone commonly used as a preservative with antibacterial ... It is also a known dermatological sensitizer and allergen; some of its side effects include flaky or …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Compounds used in a research, industrial, or household setting …
Dinoprostone
Dinoprostone is a naturally occurring prostaglandin E2 (PGE2). It has important effects in labour. It also stimulates osteoblasts to release factors which stimualtes bone resorption by osteoclasts. As a prescription drug it is used as a vaginal suppository, to prepare the cervix for labour and to induce labour.
Approved
Matched Synonyms: … (Z)-7-((1R,2R,3R)-3-hydroxy-2-((S,E)-3-hydroxyoct-1-enyl)-5-oxocyclopentyl)hept-5-enoic acid ... (E,Z)-(1R,2R,3R)-7-(3-Hydroxy-2-((3S)-(3-hydroxy-1-octenyl))-5-oxocyclopentyl)-5-heptenoic acid ... (5Z,11α,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid …
Matched Iupac: … (5Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]hept-5-enoic acid …
Matched Description: … As a prescription drug it is used as a vaginal suppository, to prepare the cervix for labour and to induce ... Dinoprostone is a naturally occurring prostaglandin E2 (PGE2). It has important effects in labour. …
Matched Products: … PROPESS OVUL 10 MG OVUL, 1 ADET ... PROSTIN E2 VAGINAL TABLET 3 mg ... Prostin E2 3 mg - Vaginaltabletten …
Matched Iupac: … (5Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]hept-5-enoic acid …
Matched Description: … As a prescription drug it is used as a vaginal suppository, to prepare the cervix for labour and to induce ... Dinoprostone is a naturally occurring prostaglandin E2 (PGE2). It has important effects in labour. …
Matched Products: … PROPESS OVUL 10 MG OVUL, 1 ADET ... PROSTIN E2 VAGINAL TABLET 3 mg ... Prostin E2 3 mg - Vaginaltabletten …
Lacosamide
Lacosamide is an antiepileptic drug used to treat seizures. As a chiral functionalized amino acid, it works by blocking slowly inactivating components of voltage-gated sodium currents. Lacosamide exhibits a stereoselective mode of interaction with sodium channels. Lacosamide was first approved by the European Commission in August 2008 and was later...
Approved
Matched Synonyms: … (R)-LACOSAMIDE 1 ... (R)-2-acetamido-N-benzyl-3- methoxypropionamide ... (+)-(2R)-2-(ACETYLAMINO)-N-BENZYL-3-METHOXYPROPANAMIDE …
Matched Iupac: … (2R)-N-benzyl-2-acetamido-3-methoxypropanamide …
Matched Description: … Lacosamide exhibits a stereoselective mode of interaction with sodium channels. ... As a chiral functionalized amino acid, it works by blocking slowly inactivating components of voltage-gated …
Matched Iupac: … (2R)-N-benzyl-2-acetamido-3-methoxypropanamide …
Matched Description: … Lacosamide exhibits a stereoselective mode of interaction with sodium channels. ... As a chiral functionalized amino acid, it works by blocking slowly inactivating components of voltage-gated …
Promazine
A phenothiazine with actions similar to chlorpromazine but with less antipsychotic activity. It is primarily used in short-term treatment of disturbed behavior and as an antiemetic. It is currently not approved for use in the United States.
Approved
Vet approved
Matched Synonyms: … N,N-dimethyl-3-(10H-phenothiazin-10-yl)-propan-1-amine ... N-Dimethylamino-1-methylethyl thiodiphenylamine ... N-(3-Dimethylaminopropyl)phenothiazine …
Matched Iupac: … dimethyl[3-(10H-phenothiazin-10-yl)propyl]amine …
Matched Description: … A phenothiazine with actions similar to chlorpromazine but with less antipsychotic activity. …
Matched Salts cas: … 53-60-1 …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists ... Heterocyclic Compounds, 3-Ring …
Matched Iupac: … dimethyl[3-(10H-phenothiazin-10-yl)propyl]amine …
Matched Description: … A phenothiazine with actions similar to chlorpromazine but with less antipsychotic activity. …
Matched Salts cas: … 53-60-1 …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists ... Heterocyclic Compounds, 3-Ring …
Rivastigmine
Rivastigmine is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer's type. Rivastigmine is a cholinesterase inhibitor that inhibits both butyrylcholinesterase and acetylcholinesterase.
Approved
Investigational
Matched Synonyms: … (S)-3-(1-(Dimethylamino)ethyl)phenyl ethylmethylcarbamate ... m-((S)-1-(Dimethylamino)ethyl)phenyl ethylmethylcarbamate …
Matched Iupac: … 3-[(1S)-1-(dimethylamino)ethyl]phenyl N-ethyl-N-methylcarbamate …
Matched Description: … Rivastigmine is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia ... Rivastigmine is a cholinesterase inhibitor that inhibits both butyrylcholinesterase and acetylcholinesterase …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Rivastigmine 1 A Pharma ... ALRIVA 3 (Rivastigmine Capsules 3 mg) ... EXELON 3 MG. …
Matched Iupac: … 3-[(1S)-1-(dimethylamino)ethyl]phenyl N-ethyl-N-methylcarbamate …
Matched Description: … Rivastigmine is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia ... Rivastigmine is a cholinesterase inhibitor that inhibits both butyrylcholinesterase and acetylcholinesterase …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Rivastigmine 1 A Pharma ... ALRIVA 3 (Rivastigmine Capsules 3 mg) ... EXELON 3 MG. …
Lumacaftor
Lumacaftor is a drug used in combination with DB08820 as the fixed dose combination product Orkambi for the management of Cystic Fibrosis (CF) in patients aged 6 years and older. Cystic Fibrosis is an autosomal recessive disorder caused by one of several different mutations in the gene for the Cystic...
Approved
Matched Synonyms: … 3-(6-{[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropane-1-carbonyl]amino}-3-methylpyridin-2-yl)benzoic …
Matched Iupac: … 3-{6-[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropaneamido]-3-methylpyridin-2-yl}benzoic acid …
Matched Description: … Lumacaftor is a drug used in combination with [DB08820] as the fixed dose combination product Orkambi ... [A20298, A20299] As a result, CF patients produce thick, sticky mucus that clogs the ducts of organs ... [A20343, L936] A wide variety of CFTR mutations correlate to the Cystic Fibrosis phenotype and are …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 3-{6-[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropaneamido]-3-methylpyridin-2-yl}benzoic acid …
Matched Description: … Lumacaftor is a drug used in combination with [DB08820] as the fixed dose combination product Orkambi ... [A20298, A20299] As a result, CF patients produce thick, sticky mucus that clogs the ducts of organs ... [A20343, L936] A wide variety of CFTR mutations correlate to the Cystic Fibrosis phenotype and are …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Rizatriptan
Rizatriptan is a second-generation triptan and a selective 5-HT1B and 5-HT1D receptor agonist. Used in the treatment of migraines, rizatriptan was first approved in the US in 1998. Rizatriptan is available in oral tablets, orally disintegrating tablets (wafers), and oral film formulations.
Approved
Matched Synonyms: … N,N-Dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]-ethanamine ... N,N-Dimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indole-3-ethanamine …
Matched Iupac: … dimethyl(2-{5-[(1H-1,2,4-triazol-1-yl)methyl]-1H-indol-3-yl}ethyl)amine …
Matched Description: … Rizatriptan is a second-generation triptan [A258918] and a selective 5-HT1B and 5-HT1D receptor …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Monoamine Oxidase A Substrates …
Matched Products: … MİGREOUT 5 MG EFERVESAN TABLET, 3 ADET ... MİGREOUT 10 MG EFERVESAN TABLET, 3 ADET ... MAXALT 10 MG RAPIDISC TABLET, 3 ADET …
Matched Iupac: … dimethyl(2-{5-[(1H-1,2,4-triazol-1-yl)methyl]-1H-indol-3-yl}ethyl)amine …
Matched Description: … Rizatriptan is a second-generation triptan [A258918] and a selective 5-HT1B and 5-HT1D receptor …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Monoamine Oxidase A Substrates …
Matched Products: … MİGREOUT 5 MG EFERVESAN TABLET, 3 ADET ... MİGREOUT 10 MG EFERVESAN TABLET, 3 ADET ... MAXALT 10 MG RAPIDISC TABLET, 3 ADET …
Empagliflozin
Empagliflozin is an inhibitor of sodium-glucose co-transporter-2 (SGLT2), the transporters primarily responsible for the reabsorption of glucose in the kidney. It is used clinically as an adjunct to diet and exercise, often in combination with other drug therapies,[L13673,L13679,L11479] for the management of type 2 diabetes mellitus. The first known inhibitor...
Approved
Matched Synonyms: … 1-chloro-4-(glucopyranos-1-yl)-2-(4-(tetrahydrofuran-3-yloxy)benzyl)benzene ... (1S)-1,5-anhydro-1-(4-chloro-3-{4-[(3S)-tetrahydrofuran-3-yloxy]benzyl}phenyl)-D-glucitol …
Matched Iupac: … (2S,3R,4R,5S,6R)-2-[4-chloro-3-({4-[(3S)-oxolan-3-yloxy]phenyl}methyl)phenyl]-6-(hydroxymethyl)oxane- …
Matched Iupac: … (2S,3R,4R,5S,6R)-2-[4-chloro-3-({4-[(3S)-oxolan-3-yloxy]phenyl}methyl)phenyl]-6-(hydroxymethyl)oxane- …
Amprenavir
Amprenavir is a protease inhibitor used to treat HIV infection.
Approved
Investigational
Matched Synonyms: … (3S)-Tetrahydro-3-furanyl ((1S,2R)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-(phenylmethyl …
Matched Iupac: … (3S)-oxolan-3-yl N-[(2S,3R)-3-hydroxy-4-[N-(2-methylpropyl)4-aminobenzenesulfonamido]-1-phenylbutan-2 …
Matched Description: … Amprenavir is a protease inhibitor used to treat HIV infection. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … (3S)-oxolan-3-yl N-[(2S,3R)-3-hydroxy-4-[N-(2-methylpropyl)4-aminobenzenesulfonamido]-1-phenylbutan-2 …
Matched Description: … Amprenavir is a protease inhibitor used to treat HIV infection. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Bosutinib
Bosutinib is a 7-alkoxy-3-quinolinecarbonitrile that functions as a potent, dual SRC and ABL tyrosine kinase inhibitor indicated for chronic myelogenous leukemia (CML), specifically Philadelphia chromosome-positive (Ph+) CML. Philadelphia chromosome is a hallmark of CML due to the reciprocal translocation t(9;22)(q34;q11), resulting in a BCR-ABL fusion protein.[A6902,A261796,A261801] The first BCR-ABL inhibitor,...
Approved
Matched Synonyms: … 4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methyl-1-piperazinyl)propoxy)-3-quinolinecarbonitrile …
Matched Iupac: … 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile …
Matched Description: … Bosutinib is a 7-alkoxy-3-quinolinecarbonitrile that functions as a potent, dual SRC and ABL tyrosine ... in a BCR-ABL fusion protein. ... [A6902,A261796,A261801] The first BCR-ABL inhibitor, [imatinib], was introduced over a decade ago as …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Iupac: … 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile …
Matched Description: … Bosutinib is a 7-alkoxy-3-quinolinecarbonitrile that functions as a potent, dual SRC and ABL tyrosine ... in a BCR-ABL fusion protein. ... [A6902,A261796,A261801] The first BCR-ABL inhibitor, [imatinib], was introduced over a decade ago as …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Enzacamene
Commonly known as 4-methylbenzylidene-camphor (4-MBC), enzacamene is a camphor derivative and an organic chemical UV-B filter. It is used in cosmetic products such as sunscreen to provide skin protection against UV rays. While its effects on the human reproductive system as an endocrine disruptor are being investigated, its use in...
Approved
Matched Synonyms: … 3-(4-methylbenzylidene)camphor ... (+/-)-3-(p-methylbenzylidene)camphor ... 3-(p-Methylbenzylidene)-DL-camphor …
Matched Iupac: … (3E)-1,7,7-trimethyl-3-[(4-methylphenyl)methylidene]bicyclo[2.2.1]heptan-2-one …
Matched Description: … Commonly known as 4-methylbenzylidene-camphor (4-MBC), enzacamene is a camphor derivative and an organic …
Matched Mixtures name: … Outback 2-in-1 Insect Repellent and Protective Sunscreen …
Matched Iupac: … (3E)-1,7,7-trimethyl-3-[(4-methylphenyl)methylidene]bicyclo[2.2.1]heptan-2-one …
Matched Description: … Commonly known as 4-methylbenzylidene-camphor (4-MBC), enzacamene is a camphor derivative and an organic …
Matched Mixtures name: … Outback 2-in-1 Insect Repellent and Protective Sunscreen …
Sumatriptan
Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches.[L6793,L6796,L6799,L6805,L6808,L6811] Sumatriptan is the first of the triptans and was made available in Europe in 1991 to treat migraines. Sumatriptan was granted FDA approval on 28 December 1992.
Approved
Investigational
Matched Synonyms: … 1-[3-(2-dimethylaminoethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide ... (3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamide ... 3-[2-(dimethylamino)ethyl]-N-methylindole-5-methanesulfonamide …
Matched Iupac: … 1-{3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}-N-methylmethanesulfonamide …
Matched Description: … Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches …
Matched Categories: … Monoamine Oxidase A Substrates …
Matched Iupac: … 1-{3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}-N-methylmethanesulfonamide …
Matched Description: … Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches …
Matched Categories: … Monoamine Oxidase A Substrates …
Vorapaxar
Vorapaxar is a tricyclic himbacine-derived selective inhibitor of protease activated receptor (PAR-1) indicated for reducing the incidence of thrombotic cardiovascular events in patients with a history of myocardial infarction (MI) or with peripheral arterial disease (PAD). By inhibiting PAR-1, a thrombin receptor expressed on platelets, vorapaxar prevents thrombin-related platelet aggregation.
Approved
Matched Synonyms: … -1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]-, ethyl ester ... -1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]-, ethyl ester ... [(1R,3aR,4aR,6R,8aR,9S,9aS)-9-{(E)-2-[5-(3-Fluorophényl)-2-pyridinyl]vinyl}-1-méthyl-3-oxododécahydronaphto …
Matched Iupac: … ethyl N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)pyridin-2-yl]ethenyl]-1-methyl-3-oxo-dodecahydronaphtho …
Matched Description: … Vorapaxar is a tricyclic himbacine-derived selective inhibitor of protease activated receptor (PAR-1) ... By inhibiting PAR-1, a thrombin receptor expressed on platelets, vorapaxar prevents thrombin-related ... indicated for reducing the incidence of thrombotic cardiovascular events in patients with a history …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Protease-activated Receptor-1 Antagonist ... Protease-activated Receptor-1 Antagonists ... Receptor, PAR-1, antagonists & inhibitors …
Matched Iupac: … ethyl N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)pyridin-2-yl]ethenyl]-1-methyl-3-oxo-dodecahydronaphtho …
Matched Description: … Vorapaxar is a tricyclic himbacine-derived selective inhibitor of protease activated receptor (PAR-1) ... By inhibiting PAR-1, a thrombin receptor expressed on platelets, vorapaxar prevents thrombin-related ... indicated for reducing the incidence of thrombotic cardiovascular events in patients with a history …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Protease-activated Receptor-1 Antagonist ... Protease-activated Receptor-1 Antagonists ... Receptor, PAR-1, antagonists & inhibitors …
Menadione
A synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone, after alkylation in vivo.
Approved
Nutraceutical
Matched Synonyms: … Vitamin K 3 …
Matched Description: … A synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted …
Matched Products: … วิตามิน เค3 ... VI-PLEX K 10 MG 3 AMPUL …
Matched Description: … A synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted …
Matched Products: … วิตามิน เค3 ... VI-PLEX K 10 MG 3 AMPUL …
Ciprofloxacin
Ciprofloxacin is a second generation fluoroquinolone that has spawned many derivative antibiotics. It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration for a number of bacterial infections.[L6469,L6472,L6475,L6478,L6481,L6484,L6487,L6490,L6493]
The first ciprofloxacin containing product was FDA approved on 22 October 1987.
Approved
Investigational
Matched Synonyms: … 1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid ... 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid ... 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid …
Matched Iupac: … 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … Ciprofloxacin is a second generation fluoroquinolone that has spawned many derivative antibiotics. ... A178870] It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration for a …
Matched Mixtures name: … InfectoCiproCort 3 mg/ml + 0,25 mg/ml Ohrentropfen, Lösung …
Matched Categories: … MATE 1 Inhibitors ... MATE 1 Substrates …
Matched Products: … N/A ... NOVAFLOX EYE DROPS 3 mg/ml ... CILOXAN STERILE OPHTHALMIC OINTMENT 3 mg/g …
Matched Iupac: … 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … Ciprofloxacin is a second generation fluoroquinolone that has spawned many derivative antibiotics. ... A178870] It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration for a …
Matched Mixtures name: … InfectoCiproCort 3 mg/ml + 0,25 mg/ml Ohrentropfen, Lösung …
Matched Categories: … MATE 1 Inhibitors ... MATE 1 Substrates …
Matched Products: … N/A ... NOVAFLOX EYE DROPS 3 mg/ml ... CILOXAN STERILE OPHTHALMIC OINTMENT 3 mg/g …
Displaying drugs 26 - 50 of 13339 in total