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Displaying drugs 1651 - 1675 of 15510 in total

Givinostat

Givinostat is a small molecule histone deacetylase (HDAC) inhibitor. It has been investigated as a treatment for a variety of inflammatory diseases, like Crohn's disease and juvenile idiopathic arthritis, cancers like leukemia and lymphoma, as well as several muscular dystrophies. In the context of muscular dystrophy, inhibitors of HDAC appear...
Approved
Investigational
Matched Description: … It has been investigated as a treatment for a variety of inflammatory diseases, like Crohn's disease and ... appear to exert their therapeutic effects by targeting pathogenic processes that cause inflammation and ... juvenile idiopathic arthritis, cancers like leukemia and lymphoma, as well as several muscular dystrophies …

Nedaplatin

Nedaplatin is a second generation platinum analog . It is less nephrotoxic than DB00515 but has proven equally effective. It was approved for use in Japan in 1995.
Approved
Investigational

Sodium tetradecyl sulfate

An anionic surface-active agent used for its wetting properties in industry and used in medicine as an irritant and sclerosing agent for hemorrhoids and varicose veins.
Approved
Investigational
Matched Description: … irritant and sclerosing agent for hemorrhoids and varicose veins. ... An anionic surface-active agent used for its wetting properties in industry and used in medicine as an …

Hydrotalcite

Approved
Experimental
Investigational
Matched Categories: … Alimentary Tract and Metabolism ... Gastric Acid Lowering Agents ... Drugs for Acid Related Disorders ... Aluminum and magnesium containing antacids …

Rabeprazole

Rabeprazole is an antiulcer drug in the class of proton pump inhibitors. It is a prodrug - in the acid environment of the parietal cells it turns into active sulphenamide form. Rabeprazole inhibits the H+, K+ATPase of the coating gastric cells and dose-dependent oppresses basal and stimulated gastric acid secretion.
Approved
Investigational
Matched Description: … and stimulated gastric acid secretion. ... It is a prodrug - in the acid environment of the parietal cells it turns into active sulphenamide form ... Rabeprazole inhibits the H+, K+ATPase of the coating gastric cells and dose-dependent oppresses basal …
Matched Categories: … Acid Reducers ... Gastric Acid Lowering Agents ... Drugs for Acid Related Disorders ... Alimentary Tract and Metabolism ... Antiinflammatory and Antirheumatic Products …

Mometasone furoate

Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and certain skin conditions[FDA Label][F4292,F4295]. It has a glucocorticoid receptor binding affinity 22 times stronger than dexamethasone and higher than many other corticosteroids as well . Mometasone furoate is formulated as a dry powder...
Approved
Investigational
Vet approved
Matched Description: … Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and ... Mometasone furoate is formulated as a dry powder inhaler, nasal spray, and ointment for its different ... It has a glucocorticoid receptor binding affinity 22 times stronger than [dexamethasone] and higher than …
Matched Mixtures name: … Hyaluronic Acid Sodium Salt 2% / Mometasone Furoate 0.1% / Niacinamide 4% …
Matched Categories: … formoterol and mometasone …
Matched Products: … Up and Up Allergy ... Nasonex Allergy and Congestion ... Nasal Allergy and Congestion Relief …

Synthetic camphor

Approved
Experimental
Matched Mixtures name: … Major Camphor and Phenol ... Up and Up Pain ... CAMPHOR (SYNTHETIC) and PHENOL …
Matched Products: … Soothe and Move Pain Relief Cream ... Arthritis and Joint Pain Relief Thayers ... Weeks and Leo Medicated Vaporizing Steam …

Triheptanoin

Triheptanoin is a source of heptanoate fatty acids, which can be metabolized without the enzymes of long chain fatty acid oxidation. In clinical trials, patients with long chain fatty acid oxidation disorders (lc-FAODs) treated with triheptanoin are less likely to develop hypoglycemia, cardiomyopathy, rhabdomyolysis, and hepatomegaly.[A214812,A214817] Complications in lc-FAOD patients...
Approved
Investigational
Matched Description: … with triheptanoin are less likely to develop hypoglycemia, cardiomyopathy, rhabdomyolysis, and hepatomegaly ... source of heptanoate fatty acids, which can be metabolized without the enzymes of long chain fatty acid ... [L14612] In clinical trials, patients with long chain fatty acid oxidation disorders (lc-FAODs) treated …
Matched Categories: … Alimentary Tract and Metabolism ... Various Alimentary Tract and Metabolism Products …

Bismuth subnitrate

Bismuth subnitrate, also referred to as bismuth oxynitrate or bismuthyl nitrate, is a highly water-soluble crystalline compound that has been used as a treatment for duodenal ulcers and anti-diarrheic agent . The use of bismuth substrate as an active ingredient in over-the-counter antacids is approved by the FDA.
Approved
Matched Description: … is a highly water-soluble crystalline compound that has been used as a treatment for duodenal ulcers and …
Matched Categories: … Alimentary Tract and Metabolism ... Gastric Acid Lowering Agents ... Drugs for Acid Related Disorders ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …

Tolvaptan

Tolvaptan is used to treat low blood sodium levels (hyponatremia) associated with various conditions like congestive heart failure, cirrhosis, and syndrome of inappropriate antidiuretic hormones (SIADH). FDA approved on May 19, 2009.
Approved
Matched Description: … levels (hyponatremia) associated with various conditions like congestive heart failure, cirrhosis, and …
Matched Products: … Jinarc 45 mg and Jinarc 15 mg Tablets ... Jinarc 60 mg and Jinarc 30 mg Tablets ... Jinarc 90 mg and Jinarc 30 mg Tablets …

Butylene glycol

Approved
Experimental
Matched Products: … Dr.g Lock and More Nourishing Mask ... Dr.g Lock and More Sensi Calming Mask ... PLAY and JOY Cologne Maca Extra Hot Lubricant PJ-LBS201-35EU …

Acetyl sulfisoxazole

Sulfisoxazole acetyl is an ester of sulfisoxazole, a broad-spectrum sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with antibacterial activity. Sulfisoxazole acetyl competes with PABA for the bacterial enzyme, dihydropteroate synthase, preventing the incorporation of PABA into dihydrofolic acid, which is the precursor of folic acid. This process causes...
Approved
Vet approved
Matched Description: … This process causes an inhibition of bacterial folic acid synthesis and de novo synthesis of purines ... and pyrimidines, resulting in cell growth arrest and cell death [L2788]. ... , which is the precursor of folic acid. …
Matched Mixtures name: … Erythromycin Ethylsuccinate and Sulfisoxazole Acetyl ... Erythromycin Ethylsuccinate and Sulfisoxazole Acetyl ... Erythromycin Ethylsuccinate and Sulfisoxazole Acetyl …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Ginger

Ginger allergenic extract is used in allergenic testing.
Approved
Matched Categories: … Herbs and Natural Products …
Matched Products: … Ginger slimming Tear and pull membrane ... Gongfu Head Soup Plant and extract platycypresssolution …

Rutin

A flavonol glycoside found in many plants, including buckwheat; tobacco; forsythia; hydrangea; viola, etc. It has been used therapeutically to decrease capillary fragility.
Approved
Experimental
Investigational
Matched Mixtures name: … KORDEL`S C TIME ACID FREE C 1000MG TABLET …

Potassium nitrate

Potassium nitrate is an inorganic salt with a chemical formula of KNO3. It is a natural source of nitrate and has been used as a constituent for several different purposes, including food preservatives, fertilizers, tree stump removal, rocket propellants, and fireworks. Potassium nitrate is a common active ingredient in toothpaste,...
Approved
Matched Description: … In addition, potassium nitrate is used as a diuretic in pigs, cattle, and horses. ... It is a natural source of nitrate and has been used as a constituent for several different purposes, ... including food preservatives, fertilizers, tree stump removal, rocket propellants, and fireworks. …
Matched Mixtures name: … Up and Up Sensitive Toothpaste ... Twice Science and Wellness Invigorating Wintergreen and Peppermint ... Sensitive Teeth and Gums …
Matched Products: … Schmidts WONDERMINT TOOTH AND MOUTH ... SprinJene Natural Sensitivity and Gum …

Pseudoephedrine

Pseudoephedrine is structurally related to ephedrine but exerts a weaker effect on the sympathetic nervous system.[A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first researched in the west in 1889. The decongestant effect of pseudoephedrine was described...
Approved
Matched Description: … drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and …
Matched Mixtures name: … Up and Up Cold and Sinus ... Up and Up Sinus and Cold D ... Up and Up allergy and congestion relief …
Matched Categories: … Alpha-and Beta-adrenergic Agonists …
Matched Products: … Up and Up Suphedrine ... Up and Up Sinus 12 Hour ... UP AND UP nasal decongestant …

Aluminium phosphate

Approved
Investigational
Matched Categories: … Alimentary Tract and Metabolism ... Gastric Acid Lowering Agents ... Drugs for Acid Related Disorders ... Aluminum and magnesium containing antacids …

Fluorouracil

A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the thymidylate synthetase conversion of deoxyuridylic acid to thymidylic acid.
Approved
Matched Description: … to thymidylic acid. ... It interferes with DNA synthesis by blocking the thymidylate synthetase conversion of deoxyuridylic acid …
Matched Categories: … Nucleic Acid Synthesis Inhibitors ... Fluorouracil and prodrugs ... Skin and Mucous Membrane Agents ... Antineoplastic and Immunomodulating Agents …

Pegloticase

Pegloticase is a porcine recombinant PEGylated uricase indicated for the treatment of chronic gout in adult patients that do not respond to other types of therapies. Pegloticase has a similar activity to rasburicase, an enzyme that metabolizes uric acid to allantoin. In gout patients treated with pegloticase, the conversion of...
Approved
Investigational
Matched Description: … uric acid concentrations. ... of pegloticase and methotrexate. ... In gout patients treated with pegloticase, the conversion of uric acid to allantoin leads to lower plasma …
Matched Categories: … Enzymes and Coenzymes ... Uric Acid-specific Enzyme …

Methantheline

Methantheline is a synthetic antispasmodic. Antispasmodics are used to relieve cramps or spasms of the stomach, intestines, and bladder. Methantheline is used to treat intestine or stomach ulcers (peptic ulcer disease), intestine problems (irritable bowel syndrome), pancreatitis, gastritis, biliary dyskinesia, pylorosplasm, or urinary problems (reflex neurogenic bladder in children).
Approved
Investigational
Matched Description: … Antispasmodics are used to relieve cramps or spasms of the stomach, intestines, and bladder. …
Matched Categories: … Alimentary Tract and Metabolism ... Acid Reducers ... Gastric Acid Lowering Agents …

Cetylpyridinium

Cetylpyridinium is a quaternary ammonium with broad-spectrum antiseptic properties. Its salt form, cetylpyridinium chloride, is typically found as an active ingredient in mouthwashes, toothpastes, lozenges, throat sprays, breath sprays, and nasal sprays. In these products, it generally mediates an antiseptic activity and protective action against dental plaque and reducing gingivitis.
Approved
Matched Description: … plaque and reducing gingivitis. ... found as an active ingredient in mouthwashes, toothpastes, lozenges, throat sprays, breath sprays, and ... In these products, it generally mediates an antiseptic activity and protective action against dental …
Matched Mixtures name: … Mouthwash and Gargle ... QCare Oral Cleansing and Suctioning System, Q4 ... Lander Orl Hygienic Mwh and Gargle …
Matched Categories: … Alimentary Tract and Metabolism ... Mouthwashes and Gargles ... Antiseptics and Disinfectants ... Blood and Blood Forming Organs ... chlorhexidine and cetylpyridinium …
Matched Products: … SmartMouth Gum and Plaque Formula ... Crest Pro-Health Gum and Breath Purify ... Qcare Oral Cleansing and Suctioning System …

Iron

A metallic element found in certain minerals, in nearly all soils, and in mineral waters. It is an essential constituent of hemoglobin, cytochrome, and other components of respiratory enzyme systems. Its chief functions are in the transport of oxygen to tissue (hemoglobin) and in cellular oxidation mechanisms. Depletion of iron...
Approved
Matched Description: … A metallic element found in certain minerals, in nearly all soils, and in mineral waters. ... It is an essential constituent of hemoglobin, cytochrome, and other components of respiratory enzyme ... Its chief functions are in the transport of oxygen to tissue (hemoglobin) and in cellular oxidation mechanisms …
Matched Mixtures name: … Folivane-Plus with Ascorbic Acid Precursors ... Multi Vitamin, Iron and Fluoride ... Multi-Vitamin Fluoride and Iron Drops …
Matched Categories: … iron, vitamin B12 and folic acid ... iron, multivitamins and folic acid ... Diet, Food, and Nutrition ... multivitamins and iron ... iron and multivitamins …

Sebelipase alfa

The lysosomal acid lipase (LAL) enzyme is found in lysosomes and is primarily responsible for the metabolism of lipids, and its absence or deficiency results in the accumulation of lipids in various organs. This lipid accumulation can lead to end-organ damage in the form of liver dysfunction or malabsorption secondary...
Approved
Investigational
Matched Description: … The lysosomal acid lipase (LAL) enzyme is found in lysosomes and is primarily responsible for the metabolism ... It was first approved by both the FDA and EMA in 2015 and is marketed under the brand name Kanuma (Alexion ... of lipids, and its absence or deficiency results in the accumulation of lipids in various organs. …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …

Olipudase alfa

Olipudase alfa is recombinant human acid sphingomyelinase. It is the first and only enzyme replacement therapy in the world for the treatment of Acid Sphingomyelinase Deficiency (ASMD), also known as Niemann–Pick disease. ASMD is a rare lysosomal storage disease caused by mutations in the SMPD1 gene, leading to a deficiency...
Approved
Investigational
Matched Description: … [A251590] It is the first and only enzyme replacement therapy in the world for the treatment of Acid ... Olipudase alfa is recombinant human acid sphingomyelinase. ... a rare lysosomal storage disease caused by mutations in the SMPD1 gene, leading to a deficiency in acid …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …

Homatropine methylbromide

Homatropine methylbromide is a quaternary ammonium muscarinic acetylcholine receptor antagonist belonging to the group of medicines called anti-muscarinics. Homatropine is used to treat duodenal or stomach ulcers or intestine problems. It can be used together with antacids or other medicine in the treatment of peptic ulcer. It may also be...
Approved
Matched Description: … It may also be used to prevent nausea, vomiting, and motion sickness. …
Matched Mixtures name: … Hydrocodone Bitartrate and Homatropine Methylbromide ... Hydrocodone Bitartrate and Homatropine Methylbromide ... Hydrocodone Bitartrate and Homatropine Methylbromide …
Matched Categories: … Alimentary Tract and Metabolism ... Belladonna and Derivatives, Plain ... homatropine methylbromide and psycholeptics …
Displaying drugs 1651 - 1675 of 15510 in total