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Displaying drugs 1 - 25 of 156 in total

Tafluprost

A prostaglandin analogue ester prodrug used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Chemically, tafluprost is a fluorinated analog of prostaglandin F2-alpha. Tafluprost was approved for use in the U.S. on February 10, 2012.
Approved
Matched Mixtures name: … TAPCOM ophthalmic solution ... TAPCOM-S OPHTHALMIC SOLUTION ... TAPCOM-S ophthalmic solution 15 micrograms/ml + 5 mg/ml, solution in single-dose container …
Matched Products: … Tafluprost Ophthalmic ... TAFLOTAN ophthalmic solution 0.0015% ... Taflotan Ophthalmic Solution 0.0015% …

Brimonidine

Brimonidine is an alpha-adrenergic agonist and 2-imidazoline derivative that was first introduced in 1996. It is considered to be a third generation alpha-2 aadrenergic receptor agonist, since it displays preferential binding at alpha-2 adrenoceptors over alpha-1 receptors. Brimonidine displays a higher selectivity toward the alpha-2 adrenergic receptors than clonidine or...
Approved
Matched Description: … [A36674] Brimonidine is also found in ophthalmic solutions in combination with [brinzolamide] under the ... [A178969] The ophthalmic solution of brimonidine was first approved by the FDA in 1996 as Alphagan [label …
Matched Mixtures name: … Brimonidine Tartrate/Timolol Maleate Ophthalmic Solution ... Brimonidine Tartrate/Timolol Maleate Ophthalmic Solution …
Matched Products: … Brimonidine Ophthalmic ... ALPHAGAN P Ophthalmic Solution 0.1% ... ALPHAGAN OPHTHALMIC SOLUTION 0.2% …

Levobunolol

A nonselective beta-adrenoceptor antagonist used in the treatment of glaucoma.
Approved
Matched Products: … Betagan 0.5% Ophthalmic Sol ... Levobunolol Hydrochloride Ophthalmic Solution ... Apo-levobunolol Ophthalmic Solution USP 0.5% …

Timolol

Timolol is a nonselective beta-adrenergic antagonist given in an eye drop solution to reduce intraocular pressure, or pressure in the eyes. It is also used in tablet form as a drug to treat hypertension. Timolol was first approved by the FDA in 1978. This drug is marketed by several manufacturers...
Approved
Matched Mixtures name: … COSOPT OPHTHALMIC SOLUTION ... COSOPT-S OPHTHALMIC SOLUTION ... Dorzolamide Hydrochloride-Timolol Maleate Ophthalmic Solution Sterile Ophthalmic Solution …
Matched Products: … TIMOPTOL OPHTHALMIC SOLUTION 0.5% ... TIMOPTOL XE 0.5% OPHTHALMIC SOLN ... TIMOPTOL-XE OPHTHALMIC SOLUTION 0.5% …

Pilocarpine

A naturally occurring alkaloid derived from the Pilocarpus plants, pilocarpine is a muscarinic acetylcholine agonist.[A262016, A262036] Pilocarpine is associated with parasympathomimetic effects by selectively working on muscarinic receptors. Pilocarpine is used to treat dry mouth and various ophthalmic conditions, including elevated intraocular pressure and glaucoma. The usage of glaucoma by...
Approved
Investigational
Matched Description: … [A262036] Pilocarpine is used to treat dry mouth and various ophthalmic conditions, including elevated …
Matched Mixtures name: … E-pilo 4 Ophthalmic Solution ... E-pilo 1 Ophthalmic Solution ... E-pilo 2 Ophthalmic Solution …
Matched Products: … Miocarpine Ophthalmic Solution 2% ... Miocarpine Ophthalmic Solution 4% ... Miocarpine Ophthalmic Solution 1% …

Travoprost

Travoprost is a synthetic isopropyl ester prodrug of a prostaglandin F2alpha (F2α) analogue and selective FP prostanoid receptor agonist. It is used to decrease intraocular pressure in open-angle glaucoma and ocular hypertension. Unlike other prostaglandin analogues, travoprost demonstrates full agonism and high selectivity at the prostanoid receptor, reporting a higher...
Approved
Matched Products: … Travoprost Ophthalmic ... Travoprost Ophthalmic Solution ... Travoprost Ophthalmic Solution 0.004% …

Cyclopentolate

A parasympatholytic anticholinergic used solely to obtain mydriasis or cycloplegia.
Approved
Matched Mixtures name: … CYCLOMYDRIL OPHTHALMIC SOLUTION ... CYCLOMYDRIL STERILE OPHTHALMIC SOLUTION …
Matched Products: … CYCLOGYL STERILE OPHTHALMIC SOLUTION 1% ... CYCLOGYL 1%-STERILE OPHTHALMIC SOLUTION 15ML ... Dom-cyclopentolate HCl Ophthalmic Solution-1% …

Gatifloxacin

Gatifloxacin is an antibiotic agent and a member of the fourth-generation fluoroquinolone family. It works by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV. It was first introduced by Bristol-Myers Squibb in 1999 under the brand name Tequin® for the treatment of respiratory tract infections. Gatifloxacin is available as...
Approved
Investigational
Withdrawn
Matched Description: … The FDA withdrew its approval for the use of non-ophthalmic drug products containing gatifloxacin due …
Matched Categories: … Ophthalmic Solutions …
Matched Products: … ZYMAR (OPHTHALMIC SOLUTION 0.3%) ... ZYMAR OPHTHALMIC SOLUTION 0.3% ... ZYMAXID (gatifloxacin ophthalmic solution) 0.5% …

Nepafenac

Nepafenac is a non-steroidal anti-inflammatory prodrug (NSAID) usually sold as a prescription eye drop. It is used to treat pain and inflammation associated with cataract surgery.
Approved
Investigational
Matched Products: … NEVANAC OPHTHALMIC SUSPENSION 0.1% ... NEVANAC (NEPAFENAC OPHTHALMIC SUSPENSION) 0.1% ... Ilevro (Nepafenac Ophthalmic Suspension 0.3%) …

Dorzolamide

Dorzolamide is a non-bacteriostatic sulfonamide derivative and topical carbonic anhydrase (CA) inhibitor that treats elevated intraocular pressure (IOP) associated with open-angle glaucoma and ocular hypertension. It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure in the eyes. Unlike oral CA inhibitors, dorzolamide...
Approved
Matched Description: … [A1304] First marketed in 1995,[A190624] dorzolamide is available in ophthalmic solutions as monotherapy …
Matched Mixtures name: … COSOPT OPHTHALMIC SOLUTION ... COSOPT-S OPHTHALMIC SOLUTION ... Dorzolamide Hydrochloride-Timolol Maleate Ophthalmic Solution Sterile Ophthalmic Solution …
Matched Products: … Dorzolamide Hydrochloride Ophthalmic Solution 2%, 10mL Ophthalmic Solution 2%, 10mL ... TRUSOPT OPHTHALMIC SOLUTION ... TRUSOPT OPHTHALMIC SOLUTION 2% …

Tropicamide

Tropicamide is an alkaloid atropine‐derived anticholinergic drug and a non‐selective antagonist of muscarinic acetylcholine (mACh) receptors. Usually available in ophthalmic formulations, tropicamide is used to cause mydriasis and cycloplegia for eye exams or ocular procedures. It is also used in combination with hydroxyamphetamine for the same indication. Oral tropicamide has...
Approved
Investigational
Matched Description: … [A230103] Usually available in ophthalmic formulations, tropicamide is used to cause mydriasis and cycloplegia …
Matched Products: … MYDRIACYL 1% OPHTHALMIC PREPARATION ... MYDRIACYL STERILE OPHTHALMIC SOLUTION 1% ... MYDRIACYL STERILE OPHTHALMIC SOLUTION 0.5% …

Emedastine

Emedastine is an antihistamine used in eye drops to treat allergic conjunctivitis.
Approved
Matched Products: … Emadine Sterile Ophthalmic Solution 0.05% ... EMADINE 0.05% STERILE OPHTHALMIC SOLUTION …

Epinastine

Epinastine is used for the prevention of itching associated with allergic conjunctivitis. It has a multi-action effect that inhibits the allergic response in 3 ways: 1. stabilizes mast cells by preventing mast cell degranulation to control the allergic response, 2. prevents histamine binding to both the H1- and H2-receptors to...
Approved
Investigational
Matched Products: … RELESTAT OPHTHALMIC SOLUTION 0.5 mg/ml ... RELESTAT (EPINASTINE HYDROCHLORIDE OPHTHALMIC SOLUTION 0.5 MG/ML) …

Moxifloxacin

Moxifloxacin is a synthetic fluoroquinolone antibiotic agent. Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment.
Approved
Investigational
Matched Products: … Moxifloxacin Ophthalmic ... Moxifloxacin ophthalmic solution ... Moxifloxacin Ophthalmic Solution …

Brinzolamide

Brinzolamide is a highly specific, non-competitive, reversible carbonic anhydrase II (CA-II) inhibitor indicated to reduce ocular pressure in patients with ocular hypertension or open-angle glaucoma. Although the exact pathophysiology of glaucoma is still unknown, one of the main hallmarks of this disease is vascular dysregulation and abnormalities.[A2049,A2051] The resulting vascular...
Approved
Matched Products: … AZOPT OPHTHALMIC SUSPENSION 1% ... AZOPT 10MG/ML OPHTHALMIC SUSPENSION …

Chlortetracycline

Chlortetracycline is a tetracycline antibiotic, and historically the first member of this class to be identified. It was discovered in 1945 by the scientist, Benjamin Minge Duggar, working at Lederle Laboratories under the supervision of Yellapragada Subbarow. He discovered that this antibiotic was the product of an actinomycete strain he...
Approved
Investigational
Vet approved
Matched Products: … CHLORTRALIM OPHTHALMIC OINTMENT 1% …

Carbamoylcholine

Carbamoylcholine, also known as carbachol, is a muscarinic agonist discovered in 1932. Carbamoylcholine was initially used as a treatment for migraines, induction of diuresis, and other parasympathetic effects. Carbamoylcholine was granted FDA approval on 28 September 1972.
Approved
Matched Products: … Miostat Ophthalmic Liq 0.01% …

Chloramphenicol

An antibiotic first isolated from cultures of Streptomyces venezuelae in 1947 but now produced synthetically. It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It acts by interfering with bacterial protein synthesis and is mainly bacteriostatic. (From Martindale, The Extra Pharmacopoeia, 29th ed, p106)...
Approved
Vet approved
Withdrawn
Matched Products: … OPTIVIS OPHTHALMIC OINTMENT ... PMS-chloramphenicol Ophthalmic Ointment ... PMS-chloramphenicol Ophthalmic Soln 0.5% …

Isosorbide

Isosorbide was previously available in an oral formulation for the reduction of intraocular pressure. It was approved by the FDA in 1980, but has since been discontinued. Currently, isosorbide is an organic nitrate currently available in the isosorbide mononitrate and isosorbide dinitrate forms, and is used for the prevention of...
Approved
Investigational

Ketotifen

Ketotifen is a benzocycloheptathiophene derivative with potent antihistaminic and mast cell stabilizing properties. It has a similar structure to some other first-generation antihistamines such as cyproheptadine and azatadine. Ketotifen was first developed in Switzerland in 1970 by Sandoz Pharmaceuticals and was initially marketed for the treatment of anaphylaxis. In the...
Approved
Matched Description: … [A231204] In the US, it is now used in an over-the-counter ophthalmic formulation for the treatment of …
Matched Products: … Jamp Ketotifen Ophthalmic ... Ketotifen Ophthalmic Solution ... ALAWAY OPHTHALMIC SOLUTION 0.25mg/mL …

Gentamicin

Gentamicin is a bactericidal aminoglycoside that was discovered and isolated from Micromonospora purpurea in 1963. It is one of the most frequently prescribed aminoglycosides due to its spectrum of activity, low cost, and availability.[A234339,A234354] Gentamicin is effective against both gram-positive and gram-negative organisms but is particularly useful for the treatment...
Approved
Vet approved
Matched Mixtures name: … Garasone Ophthalmic Ointment ... Betamycin Ophthalmic/otic Solution ... Garasone Ophthalmic and Otic Solution …
Matched Products: … Garatec Ophthalmic Dps 5mg/ml ... Garamycin Ophthalmic Drops 0.3% ... Garamycin Ophthalmic Ointment 0.3% …

Perfluorohexyloctane

Perfluorohexyloctane is a semifluorinated alkane that contains six perfluorinated carbon atoms and eight hydrogenated carbon atoms. It is an inert, slightly amphiphilic compound. Because it is a completely non-aqueous liquid, microbial growth is not possible; therefore, its drug products do not need to be combined with any preservative.[A259746, A259751] Perfluorohexyloctane...
Approved
Matched Categories: … Ophthalmic Solutions …

Erythromycin

Erythromycin is a bacteriostatic antibiotic drug produced by a strain of Saccharopolyspora erythraea (formerly Streptomyces erythraeus) and belongs to the macrolide group of antibiotics which consists of Azithromycin, Clarithromycin, Spiramycin and others. It was originally discovered in 1952. Erythromycin is widely used for treating a variety of infections, including those...
Approved
Investigational
Vet approved
Matched Products: … Erymycin Ophthalmic Ointment 5mg/g ... Erythromycin Ophthalmic Ointment USP ... Erythromycin Ophthalmic Ointment U.S.P. …

Dexamethasone

Dexamethasone, or MK-125, is a corticosteroid fluorinated at position 9 used to treat endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic, edematous, and other conditions. Developed in 1957, it is structurally similar to other corticosteroids like hydrocortisone and prednisolone. Dexamethasone was granted FDA approval on 30 October 1958....
Approved
Investigational
Vet approved
Matched Description: … corticosteroid fluorinated at position 9 used to treat endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic …
Matched Mixtures name: … TOBRADEX OPHTHALMIC OINTMENT ... TOBRADEX OPHTHALMIC SUSPENSION ... MAXITROL STERILE OPHTHALMIC OINTMENT …
Matched Products: … MAXIDEX OPHTHALMIC SUSPENSION ... MAXIDEX STERILE OPHTHALMIC OINTMENT 0.1% ... MAXIDEX STERILE OPHTHALMIC SUSPENSION 0.1% …

Maribavir

Maribavir is an inhibitor of the cytomegalovirus (CMV; HHV5) pUL97 kinase which is used to treat CMV infections in patients post-transplantation. Most standard CMV therapies, such as ganciclovir or foscarnet, target CMV DNA polymerase - while generally effective, these medications tend to promote the development of CMV resistance to DNA...
Approved
Investigational
Matched Description: … [L39322] Most standard CMV therapies, such as [ganciclovir] or [foscarnet], target CMV DNA polymerase …
Displaying drugs 1 - 25 of 156 in total