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Displaying targets 76 - 100 of 4415 in total
Ectonucleoside triphosphate diphosphohydrolase 5
Matched Polypeptides general function: … Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in ... a compensatory increase in aerobic glycolysis. ... elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. …
Phosphatidylinositol 4-kinase beta
Matched Polypeptides general function: … Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second ... Involved in Golgi-to-plasma membrane trafficking (By similarity). …
Serine/threonine-protein kinase 16
Matched Polypeptides general function: … in the mammary gland. ... May be involved in TGF-beta signaling. ... In vitro substrates include DRG1, ENO1 and EIF4EBP1. Also autophosphorylates. …
Sorcin
Matched Polypeptides general function: … Contributes to calcium homeostasis in the heart sarcoplasmic reticulum. ... Calcium-binding protein that modulates excitation-contraction coupling in the heart. …
Galectin-10
Matched Polypeptides general function: … Cysteine-type endopeptidase activity involved in apoptotic process …
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta
Matched Polypeptides general function: … Participates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. …
Cadherin-11
Matched Polypeptides general function: … They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may ... Involved in the regulation of cell migration (PubMed:33811546). …
Serine/threonine-protein kinase 10
Matched Polypeptides general function: … vitro; however such data require additional evidences in vivo. ... Serine/threonine-protein kinase involved in regulation of lymphocyte migration. ... Involved in regulation of lymphocyte migration by mediating phosphorylation of ERM proteins such as MSN …
CD276 antigen
Matched Polypeptides general function: … May be involved in the development of acute and chronic transplant rejection and in the regulation of ... May participate in the regulation of T-cell-mediated immune response. ... May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as …
Transferrin receptor
Matched Polypeptides general function: … Mediates cellular uptake of transferrin-bound iron in a non-iron dependent manner. ... May be involved in iron metabolism, hepatocyte function and erythrocyte differentiation. …
Calsequestrin-2
Matched Polypeptides general function: … Plays a role in excitation-contraction coupling in the heart and in regulating the rate of heart beats ... high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in ... Regulates the release of lumenal Ca(2+) via the calcium release channel RYR2; this plays an important role in …
Serine/threonine-protein kinase PAK 1
Matched Polypeptides general function: … Plays a role in the regulation of insulin secretion in response to elevated glucose levels. ... kinases that plays an important role in cytoskeleton dynamics, in cell adhesion, migration, proliferation ... In podocytes, promotes NR3C2 nuclear localization. …
Sodium/iodide cotransporter
Matched Polypeptides general function: … Mediates iodide uptake in the thyroid gland. …
Taste receptor type 2 member 16
Matched Polypeptides general function: … Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the …
Complement component C8 beta chain
Matched Polypeptides general function: … response by forming pores in the plasma membrane of target cells. ... Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune …
Tyrosine-protein kinase Fer
Matched Polypeptides general function: … Plays a role in leukocyte recruitment and diapedesis in response to bacterial lipopolysaccharide (LPS ... Plays a role in the insulin receptor signaling pathway and in activation of phosphatidylinositol 3-kinase ... epsilon receptor)-mediated signaling in mast cells. …
Advanced glycosylation end product-specific receptor
Matched Polypeptides general function: … an accelerated rate in diabetes. ... These are nonenzymatically glycosylated proteins which accumulate in vascular tissue in aging and at ... and in particular as a complication of diabetes. …
Outer-membrane lipoprotein LolB
Matched Polypeptides general function: … Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released …
KAT8 regulatory NSL complex subunit 3
Matched Polypeptides general function: … residues and therefore may be involved in the regulation of transcription. ... As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine …
Tumor necrosis factor receptor superfamily member 16
Matched Polypeptides general function: … in the liver (PubMed:23785138). ... nucleus (SCmgetaN) of the brain and in liver and of the genes involved in glucose and lipid metabolism ... Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal …
Copine-1
Matched Polypeptides general function: … Involved in the TNF-alpha receptor signaling pathway in a calcium-dependent manner (PubMed:14674885). ... May function in membrane trafficking (PubMed:9430674). ... Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes …
Probable ATP-dependent RNA helicase DDX5
Matched Polypeptides general function: … increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. ... Binds to the tau pre-mRNA in the stem-loop region downstream of exon 10. ... Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for …
T-complex protein 1 subunit eta
Matched Polypeptides general function: … Known to play a role, in vitro, in the folding of actin and tubulin (By similarity). …
Zinc transporter ZIP2
Matched Polypeptides general function: … a role in tumorigenesis. ... Zinc uptake may be mediated by a Zn(2+)-HCO(3)(-) symport mechanism and can function in the presence ... May be important in contact inhibition of normal epithelial cells and loss of its expression may play …
Lipoprotein MxiM
Matched Polypeptides general function: … Involved in the secretion of the Ipa antigens. …
Displaying targets 76 - 100 of 4415 in total