Name
Imines
Accession Number
DBCAT000389
Description

Organic compounds containing a carbon-nitrogen double bond where a NITROGEN atom can be attached to HYDROGEN or an alkyl or aryl group.

Drugs
DrugDrug Description
ProlineAn amino acid commonly found as a component of total parenteral nutrition.
MiglustatA glucosylceramide synthase inhibitor used for the management of mild to moderate type I Gaucher disease for patients who are not candidates for whole enzyme replacement.
MiglitolAn oral alpha-glucosidase inhibitor used to improve glycemic control by delaying the digestion of carbohydrates.
FosinoprilAn ACE inhibitor used to treat mild to moderate hypertension, congestive heart failure, and to slow the progression of renal disease in hypertensive diabetics.
CaptoprilAn ACE inhibitor used for the management of essential or renovascular hypertension, congestive heart failure, left ventricular dysfunction following myocardial infarction, and nephropathy.
GhavamiolNot Available
Pyrrole-2-CarboxylateNot Available
CyanamideA cyanide compound which has been used as a fertilizer, defoliant and in many manufacturing processes. It often occurs as the calcium salt, sometimes also referred to as cyanamide. The...
N-(2-Acetamido)Iminodiacetic AcidNot Available
Pidolic acidThere is currently no clinically approved and/or marketed medicine that relies upon pidolic acid as an active ingredient for any formal therapeutic indication. Although pidolic acid may be sold in...
DuvoglustatAn alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity.
N-AcetylprolineNot Available
L-proline betaineNot Available
MigalastatAn alpha-galactosidase A chaperone used for the treatment of Fabry disease in patients with an amenable galactosidase alpha gene (GLA) variant.
HydroxyprolineUsed in France as a combination product for the treatment of small, superficial wounds.
BoceprevirA hepatitis C virus NS3/4A protease inhibitor used in combination with other medications to treat chronic hepatitis C genotype 1 infection. Boceprevir is not indicated as monotherapy.
Technetium Tc-99m mebrofeninA diagnostic radiopharmaceutical agent used during hepatobiliary imaging tests.
Technetium Tc-99m disofeninA radiopharmaceutical diagnostic agent used for hepatobiliary scans.
AzelnidipineFor the treatment of hypertension.
PidotimodA synthetic agent with immunomodulatory properties used in patients with documented cell-mediated immunosuppression to stimulate their immunity during lung and urinary tract infections.
RaxatrigineRaxatrigine has been investigated for the treatment of Bipolar Disorder and Bipolar Depression.
DanegaptideDanegaptide has been investigated for the treatment of Focus of Study is STEMI.
Oxothiazolidinecarboxylic acidProcysteine has been used in trials studying the treatment of HIV Infections.
ZofenoprilAn ACE inhibitor indicated in the treatment of hypertension.
OxaceprolNot Annotated
FosinoprilatFosinoprilat is the active phosphinic acid metabolite of prodrug fosinopril, which is activated by esterases in vivo. It binds zinc with phosphinic acid group.
ZofenoprilatNot Available
AB192Investigated for use/treatment in diabetes mellitus type 2.
AfegostatNot Available
UlodesineUlodesine has been used in trials studying the treatment of Gout, Arthritis, Hyperuricemia, and Joint Disease.
LucerastatLucerastat is under investigation in clinical trial NCT03425539 (Efficacy and Safety of Lucerastat Oral Monotherapy in Adult Subjects With Fabry Disease).
VoruciclibVoruciclib is under investigation in clinical trial NCT03547115 (A Phase 1 Study of Voruciclib in Subjects With B-Cell Malignancies or AML).
5-OxoprolinalNot Available
FasoracetamFasoracetam is under investigation in clinical trial NCT03609619 (PART B: Efficacy and Safety of AEVI-001 in Children and Adolescents With ADHD and Without Mglur Mutations).
MetadoxineA medication used to increase the clearance of alcohol in patients with chronic alcohol dependancy.
Drugs & Drug Targets
DrugTargetType
ProlinePyrroline-5-carboxylate reductase 1, mitochondrialtarget
ProlineBifunctional glutamate/proline--tRNA ligasetarget
ProlineSodium- and chloride-dependent neutral and basic amino acid transporter B(0+)target
ProlineSodium-dependent proline transportertarget
ProlinePyrroline-5-carboxylate reductase 2target
ProlineProlyl 4-hydroxylase subunit alpha-2target
ProlineProline dehydrogenase 1, mitochondrialtarget
ProlinePeptidyl-prolyl cis-trans isomerase Htarget
ProlineProline synthase co-transcribed bacterial homolog proteintarget
ProlineProlyl 4-hydroxylase subunit alpha-1target
ProlinePeptidyl-prolyl cis-trans isomerase Btarget
ProlinePeptidyl-prolyl cis-trans isomerase F, mitochondrialtarget
ProlinePeptidyl-prolyl cis-trans isomerase Ctarget
ProlinePeptidyl-prolyl cis-trans isomerase Atarget
ProlinePeptidyl-prolyl cis-trans isomerase Gtarget
ProlineProlyl 3-hydroxylase 1target
ProlinePyrroline-5-carboxylate reductasetarget
ProlineProbable proline--tRNA ligase, mitochondrialtarget
ProlineProlyl 3-hydroxylase 2target
ProlineProlyl 3-hydroxylase 3target
ProlinePyrroline-5-carboxylate reductase 3target
ProlineTrans-L-3-hydroxyproline dehydratasetarget
ProlineProline dehydrogenase 1, mitochondrialenzyme
ProlineMonocarboxylate transporter 10transporter
MiglustatCeramide glucosyltransferasetarget
MiglitolMaltase-glucoamylase, intestinaltarget
MiglitolPancreatic alpha-amylaseenzyme
MiglitolLysosomal alpha-glucosidasetarget
MiglitolNeutral alpha-glucosidase ABtarget
MiglitolNeutral alpha-glucosidase Ctarget
FosinoprilAngiotensin-converting enzymetarget
FosinoprilSolute carrier family 15 member 1transporter
FosinoprilSolute carrier family 15 member 2transporter
CaptoprilAngiotensin-converting enzymetarget
CaptoprilSerum albumincarrier
Captopril72 kDa type IV collagenasetarget
CaptoprilMatrix metalloproteinase-9target
CaptoprilP-glycoprotein 1transporter
CaptoprilSolute carrier family 15 member 1transporter
CaptoprilSolute carrier family 22 member 6transporter
CaptoprilLeukotriene A-4 hydrolasetarget
CaptoprilB1 bradykinin receptortarget
GhavamiolAlpha-mannosidase 2target
Pyrrole-2-CarboxylateMonomeric sarcosine oxidasetarget
CyanamideCarbonic anhydrase 2target
CyanamideCathepsin Ktarget
N-(2-Acetamido)Iminodiacetic AcidPeptide deformylasetarget
Pidolic acidAlpha-amylase 2Btarget
Pidolic acidVascular endothelial growth factor Atarget
Pidolic acidPancreatic alpha-amylasetarget
Pidolic acidIg lambda-1 chain C regionstarget
Pidolic acidIg lambda chain V-II region MGCtarget
Pidolic acidTrefoil factor 2target
Pidolic acidCytochrome c2target
Pidolic acidDisintegrin and metalloproteinase domain-containing protein 28target
Pidolic acidEndo-1,4-beta-xylanasetarget
Pidolic acidDissimilatory copper-containing nitrite reductasetarget
Pidolic acidKeratin-associated protein 5-2target
Pidolic acidOrexintarget
Pidolic acidC-C motif chemokine 8target
Pidolic acidCytochrome c'target
Pidolic acidPancreatic alpha-amylaseenzyme
DuvoglustatCyclomaltodextrin glucanotransferasetarget
DuvoglustatBeta-glucosidase Atarget
DuvoglustatEndoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidasetarget
DuvoglustatMannosyl-oligosaccharide alpha-1,2-mannosidasetarget
DuvoglustatXylose isomerasetarget
N-Acetylproline(5R)-carbapenem-3-carboxylate synthasetarget
L-proline betaineGlycine betaine-binding periplasmic proteintarget
MigalastatAlpha-galactosidase Atarget
MigalastatUDP-glucuronosyltransferase 1-1enzyme
HydroxyprolineProton-coupled amino acid transporter 1transporter
BoceprevirCytochrome P450 3A4enzyme
BoceprevirCytochrome P450 3A5enzyme
BoceprevirP-glycoprotein 1transporter
BoceprevirNS3/4A proteintarget
Technetium Tc-99m mebrofeninSolute carrier organic anion transporter family member 1B1transporter
Technetium Tc-99m mebrofeninSolute carrier organic anion transporter family member 1B3transporter
AzelnidipineCytochrome P450 3A4enzyme
AzelnidipineVoltage-dependent L-type calcium channel subunit beta-1target
ZofenoprilAngiotensin-converting enzymetarget
ZofenoprilatCytosol aminopeptidasetarget
AB192Myeloperoxidaseenzyme
AfegostatEndoglucanase 5Atarget
AfegostatBeta-glucosidase Atarget
AfegostatPossible cellulase CelA1 (Endoglucanase) (Endo-1,4-beta-glucanase) (FI-cmcase) (Carboxymethyl cellulase)target
5-OxoprolinalAcidic cytochrome c3target