Porphyrins
- Name
- Porphyrins
- Accession Number
- DBCAT001084
- Description
A group of compounds containing the porphin structure, four pyrrole rings connected by methine bridges in a cyclic configuration to which a variety of side chains are attached. The nature of the side chain is indicated by a prefix, as uroporphyrin, hematoporphyrin, etc. The porphyrins, in combination with iron, form the heme component in biologically significant compounds such as hemoglobin and myoglobin.
- Drugs
Drug Drug Description Porfimer sodium A hematoporphyrin derivative used to treat esophageal cancer, endobronchial cancer, and high grade dysplasia in Barrett's Esophagus. Bacteriochlorophyll A A specific bacteriochlorophyll that is similar in structure to CHLOROPHYLL A. N-Methylmesoporphyrin N-methylmesoporphyrin is a solid. This compound belongs to the porphyrins. These are compounds containing a fundamental skeleton of four pyrrole nuclei united through the alpha-positions by four methine groups to... Chlorophyll A Not Available Protoporphyrin Not Available Hydrogenobyrinic acid Not Available Mesoheme The color-furnishing portion of hemoglobin. It is found free in tissues and as the prosthetic group in many hemeproteins. Siroheme Not Available Ferroheme C Not Available Hemin An iron-containing porphyrin injection used for the relief of recurrent attacks of acute intermittent porphyria (AIP) associated with the menstrual cycle when carbohydrate therapy is not effective. Diacetyldeuteroheme Not Available Heme D Not Available Coproporphyrin I Not Available Coproporphyrinogen III Not Available Chlorophyll B A light, silvery, metallic element. It has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. Its salts are essential in nutrition, being required for the activity of... Verdoheme Not Available Stannsoporfin Investigated for use/treatment in liver disease, metabolic disease, and pediatric indications. Motexafin lutetium Investigated for use/treatment in brain cancer, breast cancer, cervical dysplasia/cancer, prostate cancer, cancer/tumors (unspecified), coronary artery disease, macular degeneration, and peripheral vascular disease. Motexafin gadolinium Investigated for use/treatment in brain cancer, cancer/tumors (unspecified), lung cancer, and lymphoma (non-hodgkin's). AEOL-10150 Investigated for use/treatment in amyotrophic lateral sclerosis (ALS). Temoporfin A photosensitizer used to treat squamous cell carcinomas of the head and neck. Hematin Not Annotated 2-(1-Hexyloxyethyl)-2-devinyl pyropheophorbide-a 2-(1-Hexyloxyethyl)-2-devinyl pyropheophorbide-a is under investigation in clinical trial NCT01668823 (Photodynamic Therapy in Treating Patients With Lung Cancer). Dihematoporphyrin ether Dihematoporphyrin ether is under investigation in clinical trial NCT00118222 (High Light and Low Light Dose PDT in Glioma). Verteporfin A benzoporphyrin derivative used to treat pathological myopia, ocular histoplasmosis, and choroidal neovascularization in macular degeneration. Padeliporfin Not Annotated Zinc protoporphyrin Not Available Hemoporfin A porphyrin derivative combined with vitamin B12 for the treatment of asthenia. Tin protoporphyrin IX Not Available Sodium copper chlorophyllin Sodium copper chlorophyllin (SCC) is a water-soluble and bright green mixture derived from natural chlorophyll that has potential antimutagenic and antioxidant properties . This compound is used as a food... - Drugs & Drug Targets