- Accession Number
A group of compounds containing the porphin structure, four pyrrole rings connected by methine bridges in a cyclic configuration to which a variety of side chains are attached. The nature of the side chain is indicated by a prefix, as uroporphyrin, hematoporphyrin, etc. The porphyrins, in combination with iron, form the heme component in biologically significant compounds such as hemoglobin and myoglobin.
Drug Drug Description Verteporfin A benzoporphyrin derivative used to treat pathological myopia, ocular histoplasmosis, and choroidal neovascularization in macular degeneration. Hemoporfin A porphyrin derivative combined with vitamin B12 for the treatment of asthenia. Porfimer sodium A hematoporphyrin derivative used to treat esophageal cancer, endobronchial cancer, and high grade dysplasia in Barrett's Esophagus. N-Methylmesoporphyrin N-methylmesoporphyrin is a solid. This compound belongs to the porphyrins. These are compounds containing a fundamental skeleton of four pyrrole nuclei united through the alpha-positions by four methine groups to... Protoporphyrin Not Available Hydrogenobyrinic acid Not Available Mesoheme The color-furnishing portion of hemoglobin. It is found free in tissues and as the prosthetic group in many hemeproteins. Siroheme Not Available Ferroheme C Not Available Hemin An iron-containing porphyrin injection used for the relief of recurrent attacks of acute intermittent porphyria (AIP) associated with the menstrual cycle when carbohydrate therapy is not effective. Diacetyldeuteroheme Not Available Heme D Not Available Coproporphyrin I Not Available Zinc protoporphyrin Not Available Coproporphyrinogen III Not Available Verdoheme Not Available Stannsoporfin Investigated for use/treatment in liver disease, metabolic disease, and pediatric indications. Motexafin lutetium Investigated for use/treatment in brain cancer, breast cancer, cervical dysplasia/cancer, prostate cancer, cancer/tumors (unspecified), coronary artery disease, macular degeneration, and peripheral vascular disease. Motexafin gadolinium Investigated for use/treatment in brain cancer, cancer/tumors (unspecified), lung cancer, and lymphoma (non-hodgkin's). AEOL-10150 Investigated for use/treatment in amyotrophic lateral sclerosis (ALS). Temoporfin A photosensitizer used to treat squamous cell carcinomas of the head and neck. Hematin Not Annotated Dihematoporphyrin ether Dihematoporphyrin ether is under investigation in clinical trial NCT00118222 (High Light and Low Light Dose PDT in Glioma). Tin protoporphyrin IX Not Available Heme arginate Not Available Zinc mesoporphyrin Not Annotated Ferroheme Not Annotated
- Drugs & Drug Targets