Orthostatic Hypotension (DBCOND0028921)

Identifiers

Synonyms
Postural/orthostatic hypotension / Postural Hypotension / Orthostatic hypotension / Hypotension orthostatic / Hypotension, Orthostatic / Hypotension postural / Orthostatic hypotension (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Etilefrine
An adrenergic agonist primarily of α1 and β1 receptors used as an anti-hypotensive.
No drug targets
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT01866787
Study on Baroreceptor Function in Relation to Orthostatic Blood Pressure Regulation After Hip SurgeryNo drug interventionsNot AvailableNot Availableunknown_status
NCT00581477
Treatment of Orthostatic Hypotensiontreatment2 / 3terminated
NCT05230147
Spinal Cord Stimulation for Orthostatic HypotensionNo drug interventionstreatmentNot Availablecompleted
NCT00103597
Efficacy of Therapeutic Interventions for Orthostatic Hypotension in Parkinson's Disease and Multiple System Atrophytreatment1completed
NCT03482297
Automated Abdominal Binder for Orthostatic Hypotensiontreatment1 / 2recruiting
NCT02726711
Reduction in Splanchnic Capacitance Contributes to Sympathetically Dependent Hypertension in Autonomicbasic_science1active_not_recruiting
NCT00977171
Study To Assess The Clinical Benefit Of Droxidopa In Subjects With Chronic Fatigue Syndrometreatment2terminated
NCT03248271
Effects of Insulin on Hypotension and SarcopeniaNot AvailableNot Availablewithdrawn
NCT00004478
Droxidopa in Treating Patients With Neurogenic HypotensiontreatmentNot Availablecompleted
NCT04440085
RaGuS Trial by Postoperative Patientstreatment4unknown_status
NCT00117585
Orthostatic Hypotension in Rehabilitation PatientstreatmentNot Availablecompleted
NCT03900000
Improved Orthostatic Tolerance = Better Cognitive Function in Parkinson's DiseaseNo drug interventionssupportive_careNot Availablecompleted
NCT05487300
Effect of Levodopa on Cardiovascular Autonomic Function in Parkinson's Diseaseother2 / 3completed
NCT00748059
The Pathophysiology of Orthostatic Hypotensionscreening1completed
NCT00046475
A Study for Patients With Neurogenic Orthostatic Hypotensiontreatment4completed
NCT00426842
A Dose Response Trial Using 5 and 10 Mg of Midodrine Hydrochloridetreatment2completed
NCT03555799
Evaluation of Changes of Venous Return After Spinal and Epidural Analgesia and Anesthesia by Ultrasound Guided Vena Cava Diameter MeasurementNo drug interventionsNot AvailableNot Availablecompleted
NCT05304806
Effective Volemia in Older Adults With Orthostatic HypotensionNo drug interventionsNot AvailableNot Availablecompleted
NCT02632318
Dawn Simulation and Postural HypotensionNo drug interventionsbasic_science4completed
NCT03674541
The Exercise Response to Pharmacologic Cholinergic Stimulation in Myalgic Encephalomyelitis / Chronic Fatigue Syndrometreatment2completed
NCT02919917
Treatment of Post-SCI Hypotensiontreatment2 / 3completed
NCT00835224
Safety and Efficacy of L-NAME and Midodrine to Increase MAPtreatment2completed
NCT03732716
Sarcopenia and Orthostatic HypotensionNo drug interventionsNot AvailableNot Availableunknown_status
NCT00580996
Water and the Gastropressor Response - TachyphylaxisNo drug interventionsotherNot Availableactive_not_recruiting
NCT06188663
SalT Supplementation in Older Adults With Orthostatic Intolerance DisordersNo drug interventionstreatment2recruiting
NCT05731986
Spinal Cord Transcutaneous Stimulation Effect on Blood Pressure in Acute Spinal Cord Injury (SCI)No drug interventionstreatmentNot Availablerecruiting
NCT04902222
Orthostatic Intolerance and Hypotension After Administration of Morphine in Patients Prior to Hip or Knee ArthroplastyNot AvailableNot Availableunknown_status
NCT04510922
Lundbeck TOMs Orthostatic Hypotensionother4completed
NCT02429557
Hemodynamic Mechanisms of Abdominal Compression in the Treatment of Orthostatic Hypotension in Autonomic Failureother1recruiting
NCT01705626
Screening for the Transthyretin-Related Familial Amyloidotic Polyneuropathy (TTR FAP)No drug interventionsNot AvailableNot Availablecompleted
NCT01316666
Norepinephrine Transporter Blockade as a Pathological Biomarker in Neurogenic Orthostatic HypotensionNo drug interventionsNot AvailableNot Availablecompleted
NCT04510974
RAAS and Arterial Stiffness in SCINo drug interventionsNot AvailableNot Availableunknown_status
NCT01874782
Transcranial Electrical Stimulation for Management of Orthostatic Instability in Acute Cervical Spinal Cord InjuryNo drug interventionstreatment2completed
NCT02726776
Suspension SyndromeNo drug interventionsbasic_scienceNot Availablecompleted
NCT04195360
Postoperative Incidence of Orthostatic Intolerance and Hypotension in Primary Unicompartmental Knee Arthroplasty (UKA)No drug interventionsNot AvailableNot Availableunknown_status
NCT00223691
Treatment of Orthostatic Hypotension in Autonomic FailureNot Available1completed
NCT04141891
Advancing Understanding of Transportation OptionsNo drug interventionshealth_services_researchNot Availablecompleted
NCT04493372
Deciphering Preserved Autonomic Function After Spinal Cord InjuryNo drug interventionsdiagnosticNot Availablerecruiting
NCT05295810
Hypercapnia in Orthostatic HypotensionNo drug interventionstreatmentNot Availablerecruiting
NCT06039410
A Novel Device for the Treatment of Postural Hypotension - a Signal of Effectiveness Study.No drug interventionstreatmentNot Availablerecruiting
NCT02963181
Effects of Melatonin to Reduce Nocturnal Hypertension in Patients With Neurogenic Orthostatic Hypotensiontreatment0terminated
NCT03602014
Dose Response to the Norepinephrine Precursor Droxidopa in Hypotensive Individuals With Spinal Cord Injurytreatment4completed
NCT02123303
Orthostatic Hypotension Among VeteransNo drug interventionsNot AvailableNot Availablecompleted
NCT01521221
Assessment of Hand-grip in the Prevention of Postural Orthostatic HypotensionNo drug interventionsprevention1unknown_status
NCT00962884
Breathing Device for Orthostatic Hypotension (OH)No drug interventionstreatmentNot Availablewithdrawn
NCT01362751
Orthostatic Hypotension in Elderly Nursing Home ResidentsNo drug interventionsNot AvailableNot Availablecompleted
NCT05529147
The Effects of Medication Induced Blood Pressure Reduction on Cerebral Hemodynamics in Hypertensive Frail ElderlyNo drug interventionsNot AvailableNot Availablecompleted
NCT06439498
Frequency of Orthostatic Hypotension in Patients Who Underwent ColonoscopyNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT03721393
Data Collection - Of Syncope Tilt Table Testing StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT01612078
Phase 3 Study to Evaluate the Efficacy and Safety of Droxidopa on Orthostatic Hypotension Treatment in Hemodialysis Patientstreatment3terminated
NCT00248807
A Study of Blood Pressure and Blood Supply to the Brain in Persons With a Spinal Cord Injury.health_services_researchNot Availablecompleted
NCT05982652
Heart Rate Variability and Its Association With Symptom of Orthostatic Hypotension in Spinal Cord InjuryNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT01559675
Trial Comparing Low Dose and High Dose Steroids in Patients Undergoing Colorectal SurgerypreventionNot Availablecompleted
NCT05725499
The Effect of Transcutaneous Stimulation on Blood Pressure in Spinal Cord Injury (SCI)No drug interventionstreatmentNot Availablerecruiting
NCT02700399
Study of Pulse Pressure During Tilttable and Erigo® in Adult Patients With Acquired Brain InjuryNo drug interventionstreatmentNot Availablecompleted
NCT00137319
Impedance Threshold Device Tilt StudyNo drug interventionstreatmentNot Availableterminated
NCT05941819
ARC Therapy to Restore Hemodynamic Stability and Trunk Control in People With Spinal Cord InjuryNo drug interventionstreatmentNot Availablerecruiting
NCT06255717
The Effect of Rehabilitation Training on Orthostatic Hypotension in Parkinson's PatientsNo drug interventionssupportive_careNot Availablerecruiting
NCT03354234
Evaluation of the ORTHO-LBNP SystemNo drug interventionsbasic_scienceNot Availablecompleted
NCT05729724
Effect of Pharmacological Interventions on Systolic Blood Pressure Drops (SynABPM 2 Proof-of-concept)No drug interventionsNot AvailableNot Availablecompleted
NCT02179216
Evaluation of the Effect of Hydration About Orthostatic Hypotension in the Elderly. Difference With Venous CompressionNo drug interventionspreventionNot Availableunknown_status
NCT03743116
Postoperative Orthostatic Intolerance and Hypotension in Unilateral TKANo drug interventionsNot AvailableNot Availablecompleted
NCT04842058
Pathophysiologic Hemodynamics After Primary Unilateral Total Hip Arthroplasty in Patients Receiving ACEIs and ARBsNo drug interventionsNot AvailableNot Availableunknown_status
NCT06328335
The Effect of Rehabilitation Training on Orthostatic Hypotension in Parkinson's PatientsNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT02897063
Effects of Midodrine and Droxidopa on Splanchnic Capacitance in Autonomic Failurebasic_science1recruiting
NCT00046163
A Phase IV Study in Subjects With Neurogenic Orthostatic Hypotensiontreatment4terminated
NCT04399486
Hemodynamic Effects of Aquatic vs. Land Exercise in Patients With Orthostatic HypotensionNo drug interventionstreatmentNot Availablewithdrawn
NCT00824330
Home-Based Walking Study in Older Adults With Type 2 DiabetesNo drug interventionsotherNot Availablecompleted
NCT05960448
Autonomic Effects of Spinal Cord Stimulation in Spinal Cord InjuryNo drug interventionstreatmentNot Availablerecruiting
NCT05233865
Hemodynamic Effects During Land vs Water Exercise for Older Adults With Orthostatic HypotensionNo drug interventionsbasic_scienceNot Availablecompleted
NCT04029974
Speed of Robotic Leg Movements and Orthostatic Hypotension in Subacute SCINo drug interventionstreatmentNot Availablerecruiting
NCT01030874
Orthostatic Hypotension Treatment on Rehab UnitNo drug interventionstreatmentNot Availablecompleted
NCT03343574
Cardiovascular Effects of Exercise in Patients With Parkinson's DiseaseNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT05400174
Blood Pressure Effects on Cognition and Brain Blood Flow in PDNo drug interventionsdiagnosticNot Availablerecruiting
NCT03759574
Pathophysiologic Hemodynamics After Primary Unilateral Total Hip Arthroplasty (THA)No drug interventionsNot AvailableNot Availableunknown_status
NCT02505282
Vitamin K Status and Markers of Vascular Function in Patients With and Without Postural HypotensionNo drug interventionsNot AvailableNot Availablecompleted
NCT04369131
Controlling Orthostatic Hypotension in People With Cervical Spinal Cord InjuryNo drug interventionstreatmentNot Availableenrolling_by_invitation
NCT00491231
Is Orthostatic Hypotension Associated With Nondipping HypertensionNo drug interventionsNot AvailableNot Availableunknown_status
NCT05647473
Efficacy, Safety and Response Predictors of Adjuvant Astragalus for Cognition in Orthostatic HypotensionNo drug interventionstreatment2recruiting
NCT00581373
Water and the Gastropressor Response - Diurnal VariabilityNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT00807976
Orthostatic Hypotension and Diabetes MellitusNo drug interventionsNot AvailableNot Availablecompleted
NCT05621460
The Effect of Water Carbonation on Orthostatic ToleranceNo drug interventionstreatmentNot Availablerecruiting
NCT01223391
Abdominal Compression in Orthostatic HypotensionNo drug interventionstreatmentNot Availablecompleted
NCT00555880
Study to Assess the Benefit of Midodrine in the Treatment of Patients With Neurogenic Orthostatic Hypotensiontreatment4completed
NCT01176240
A Two Part Study (306A/306B) to Assess Droxidopa in Treatment of NOH in Patients With Parkinson's Diseasetreatment3completed
NCT00004268
Phase II Study of Midodrine for Neurogenic Orthostatic Hypotensiontreatment2completed
NCT02280369
Posture Detection for Automated Abdominal BinderNo drug interventionsNot AvailableNot Availablecompleted
NCT01518946
Tilt-Table Study of the Clinical Efficacy of Midodrine in Symptomatic Orthostatic Hypotensiontreatment4completed
NCT01914146
Insulin Therapy and Falls Due to Orthostatic HypotensionNo drug interventionsdiagnosticNot Availablewithdrawn
NCT01370512
Droxidopa / Pyridostigmine in Orthostatic Hypotensiontreatment2suspended
NCT00452712
Orthostatic Hypotension in Children With Acute Febrile IllnessNo drug interventionsNot AvailableNot Availableunknown_status
NCT01891110
Prevention of Orthostatic Hypotension With Electric Stimulation in Persons With Acute SCINo drug interventionstreatmentNot Availablecompleted
NCT05358210
Effects of Blueberries in Older AdultsNo drug interventionspreventionNot Availablecompleted
NCT05728255
Assessment of the Mechanism of Non-cardiac SyncopeNo drug interventionsNot AvailableNot Availablecompleted
NCT02705755
TD-9855 Phase 2 in Neurogenic Orthostatic Hypotension (nOH)treatment2completed
NCT02154243
An Open Label Trial to Decrease Signs and Symptoms of Orthostatic Hypotension Using Midodrine or Intravenous Fluid Bolus in Patients Following Total Hip ArthroplastytreatmentNot Availableterminated
NCT02307526
Acetylcholinesterase Inhibition and Orthostatic Hypotension in SCItreatment2completed
NCT03593512
Deep Brain Stimulation for Autonomic and Gait Symptoms in Multiple System AtrophyNo drug interventionstreatmentNot Availablecompleted