Solar Lentigines (DBCOND0036306)

Identifiers

Synonyms

Not Available

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Tretinoin	A vitamin A derivative used to treat acne vulgaris and certain types of promyelocytic leukemia, as well as various skin conditions in over-the-counter medications.	Retinoic acid receptor gammatarget Retinoic acid receptor RXR-betatarget Aldehyde dehydrogenase 1A1target Retinoic acid-induced protein 3target Retinoic acid receptor RXR-gammatarget Retinal dehydrogenase 2target Retinoic acid receptor responder protein 1target Cytochrome P450 2C8enzyme Cellular retinoic acid-binding protein 1transporter Cellular retinoic acid-binding protein 2transporter Cytochrome P450 2B6enzyme Cytochrome P450 3A4enzyme Cytochrome P450 3A5enzyme Cytochrome P450 2A6enzyme Cytochrome P450 3A7enzyme Cytochrome P450 2C18enzyme Cytochrome P450 2C9enzyme Cytochrome P450 4A11enzyme Cytochrome P450 1A1enzyme Retinoic acid receptor alphatarget Retinoic acid receptor betatarget Lipocalin-1target Odorant-binding protein 2atarget Retinol-binding protein 4target Albumincarrier [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrialtarget Retinoic acid receptor RXR-alphatarget Carcinoembryonic antigentarget UDP-glucuronosyltransferase 2B7enzyme Cytochrome P450 2E1enzyme Cytochrome P450 26A1enzyme Cellular retinoic acid-binding protein 1target

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT02153697	Comparative Study of the Therapy of Solar Lentigines With a Q-switched Rubin Laser Versus a Bleaching Cream	No drug interventions	treatment	Not Available	completed
NCT01778179	A Fixed Triple Combination Cream for Solar Lentigines Associated to Cryotherapy	Fluocinolone acetonide Hydroquinone Tretinoin	prevention	Not Available	completed
NCT01885871	Laser Removal of Age (Sun) Spots on Hands	No drug interventions	treatment	Not Available	completed
NCT04583852	Evaluate the Efficacy and Safety of Brightening Micro-needle Patch on Facial Solar Lentigines	No drug interventions	treatment	Not Available	completed
NCT00386204	Side Effects of Q-Switched Ruby Laser for the Treatment of Lentigines in Light and Dark Skin Types	No drug interventions	treatment	2	completed
NCT01249469	Evaluate the Lightening Effect of the Whitening Cosmetic Product BEX-2011	No drug interventions	treatment	Not Available	unknown_status