Nitrogen Compounds

Name
Nitrogen Compounds
Accession Number
DBCAT000269
Description

Inorganic compounds that contain nitrogen as an integral part of the molecule.

Drugs
DrugDrug Description
SuccinylcholineA depolarizing skeletal muscle relaxant used adjunctly to anesthesia and for skeletal muscle relaxation during intubation, mechanical ventilation, and surgical procedures.
CarbamoylcholineA direct acting miotic agent administered ophthalmically to decrease intraocular pressure after cataract surgery, and to induce miosis during surgery.
Nitric OxideA vasodilating agent used in the treatment of hypoxic respiratory failure in premature neonates.
DemecariumFor the topical treatment of chronic open-angle glaucoma.
GlycopyrroniumAn anticholinergic agent used to treat hyperhidrosis, severe drooling, COPD, used with other medications to treat ulcers, and used in anesthesia.
BethanecholA muscarinic agonist used to treat postoperative and postpartum nonobstructive functional urinary retention and neurogenic atony of the bladder with retention.
MethacholineA parasympathomimetic bronchoconstrictor used to diagnose bronchial hyperreactivity in subjects who do not have clinically apparent asthma.
MethylnaltrexoneA μ-opioid antagonist used for the treatment of opioid-induced constipation in palliative patients that are inadequately responding to laxative therapy.
Nitrous acidAn iron binder used to reverse life-threatening acute cyanide poisoning.
AmmoniaIndicated for use as a smelling salt to treat or prevent fainting. (when radiolabelled) Indicated for diagnostic PET imaging of the myocardium under rest or pharmacologic stress conditions to evaluate...
TridihexethylUsed as an adjunct in the treatment of peptic ulcer disease and in Acquired nystagmus
CisplatinA platinum based chemotherapy agent used to treat various sarcomas, carcinomas, lymphomas, and germ cell tumors.
EmbutramideNot Available
IsopropamideA long-acting anticholinergic drug used to relieve symptoms of spastic and painful symptoms of gastrointestinal conditions and symptoms of flu, colds, and related conditions.
GhavamiolNot Available
N-Dodecyl-N,N-Dimethyl-3-Ammonio-1-PropanesulfonateNot Available
DodecyltrimethylammoniumNot Available
TetramethylammoniumNot Available
DidecyldimethylammoniumA disinfectant and microbicidal agent used in a variety of products.
Ammonium chlorideExpectorant in cough syrups. The ammonium ion (NH4+) in the body plays an important role in the maintenance of acid-base balance. The kidney uses ammonium (NH4+) in place of sodium...
Ferric ammonium citrateNot Annotated
ThonzoniumA cationic surfactant used to disperse exudate and cellular debris, as well as enhance the penetration of antimicrobials.
Brilliant green cationAn ingredient used in topical medications to prevent infections of the umbilical cord.
IchthammolIchthammol is also referred to as ammonium bituminosulfonate or ammonium bituminosulphonate. It is an ammonium salt of dark sulfonated shale oil (bituminous schists) produced via distillation of the oil followed...
CetalkoniumAn antiseptic used as a preservative or to treat certain topical infections.
DomiphenAnti-infective (topical), it is used for the treatment of Acute Infectious Dental Diseases and other conditions.
PlatinumPlatinum is under investigation for the treatment of Metastatic Breast Cancer, Non-small Cell Lung Cancer, Gastric Large Cell Neuroendocrine Carcinoma, Colorectal Large Cell Neuroendocrine Carcinoma, and Pancreatic Large Cell Neuroendocrine...
MethylbenactyziumNot Annotated
Mercuric amidochlorideNot Annotated
ValethamateAn anticholinergic medication used to symptomatically manage conditions involving smooth muscle spasms including spastic constipation, dysmenorrhea, and gastrointestinal tract cramping.
OtiloniumA spasmolytic medication used to treat irritable bowel syndrome (IBS).
PenthienateNot Annotated
DioctyldimoniumNot Annotated
DistearyldimoniumNot Annotated
Nitric acidNot Annotated
NitroprussideA direct acting vasodilator used to treat hypertension, to induce controlled hypotension to reduce postoperative bleeding, and to manage acute heart failure.
CyanamideA cyanide compound which has been used as a fertilizer, defoliant and in many manufacturing processes. It often occurs as the calcium salt, sometimes also referred to as cyanamide. The...
NOV-002Investigated for use/treatment in breast cancer, lung cancer, and ovarian cancer.
NCX 701Investigated for use/treatment in pain (acute or chronic).
Nitrous oxideAn inhalatory gas used as an adjunct to improve oxygenation and reduce the need for extracorporeal membrane oxygenation in certain neonates with hypoxic respiratory failure.
Prussian blueA chelating agent used to reduce the extent of systemic contamination with radioactive cesium and/or radioactive or non-radioactive thallium.
Calcium carbimideCalcium carbimide has not been approved by the FDA but the intended indication is for the treatment of alcoholism. This medication was marketed in Canada, United Kingdom and Europe under...
Silver nitrateSilver nitrate is an inorganic compound with the chemical formula AgNO3. In its solid form, silver nitrate is coordinated in a trigonal planar arrangement. It is often used as a...
Potassium nitrateA medication used to cauterize small wounds, remove granulation tissue, warts, and verrucae, and treat tooth sensitivity.
IndiumIndium has been used in trials studying the basic science of Clear Cell Renal Cell Carcinoma.
NitriteNitrite is under investigation for the treatment of Heart Failure.
CHS-828CHS-828 has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.
TrabodenosonTrabodenoson has been used in trials studying the treatment of Ocular Hypertension (OHT) and Primary Open-Angle Glaucoma (POAG).
Aminoethyl nitrateNot Annotated
TrolnitrateNot Annotated
NitrateNot Annotated
Chromic nitrateIndicated for use as a supplement to intravenous solutions given for total parenteral nutrition (TPN), to maintain chromium serum levels and to prevent depletion of endogenous stores and subsequent deficiency...
Sodium nitrateNot Annotated
NCX-1000NCX-1000 is under investigation in clinical trial NCT00414869 (Preliminary Efficacy and Tolerability of NCX-1000 After Repeated Oral Doses in Patients With Elevated Portal Pressure).
AzvudineAzvudine is under investigation in clinical trial NCT04668235 (Study on Safety and Clinical Efficacy of AZVUDINE in COVID-19 Patients (Sars-cov-2 Infected)).
Ethyl nitriteAn ingredient in cough syrups for symptomatic treatment of cough, cold, bronchitis, and phlegm.
Drugs & Drug Targets
DrugTargetType
SuccinylcholineCholinesteraseenzyme
SuccinylcholineMuscarinic acetylcholine receptor M2target
SuccinylcholineMuscarinic acetylcholine receptor M3target
SuccinylcholineNeuronal Acetylcholine (nACh) Receptor Subunitstarget
CarbamoylcholineMuscarinic acetylcholine receptor M1target
CarbamoylcholineMuscarinic acetylcholine receptor M2target
CarbamoylcholineNeuronal acetylcholine receptor subunit alpha-2target
CarbamoylcholineCytosolic phospholipase A2enzyme
CarbamoylcholineMuscarinic acetylcholine receptor M3target
CarbamoylcholineMuscarinic acetylcholine receptor M4target
CarbamoylcholineAcetylcholinesteraseenzyme
Nitric OxideGuanylate cyclase soluble subunit alpha-2target
Nitric OxideAldehyde dehydrogenase, mitochondrialenzyme
Nitric OxideCytochrome P450 1A2enzyme
Nitric OxideCytochrome P450 2B6enzyme
Nitric OxideCytochrome P450 3A4enzyme
Nitric OxideMetallothionein-1Atarget
Nitric OxideIndoleamine 2,3-dioxygenase 1target
DemecariumAcetylcholinesterasetarget
DemecariumCholinesterasetarget
GlycopyrroniumMuscarinic acetylcholine receptor M1target
GlycopyrroniumMuscarinic acetylcholine receptor M3target
GlycopyrroniumMuscarinic acetylcholine receptor M2target
GlycopyrroniumCytochrome P450 2D6enzyme
GlycopyrroniumCytochrome P450 1A2enzyme
GlycopyrroniumCytochrome P450 2B6enzyme
GlycopyrroniumCytochrome P450 2C9enzyme
GlycopyrroniumCytochrome P450 2C18enzyme
GlycopyrroniumCytochrome P450 2C19enzyme
GlycopyrroniumCytochrome P450 3A4enzyme
GlycopyrroniumSolute carrier family 22 member 2transporter
GlycopyrroniumMultidrug and toxin extrusion protein 1transporter
GlycopyrroniumMuscarinic acetylcholine receptor M4target
GlycopyrroniumMuscarinic acetylcholine receptor M5target
GlycopyrroniumSerum albumincarrier
Glycopyrroniumalpha1-acid glycoproteincarrier
BethanecholMuscarinic acetylcholine receptor M2target
BethanecholMuscarinic acetylcholine receptor M1target
BethanecholMuscarinic acetylcholine receptor M3target
BethanecholMuscarinic acetylcholine receptor M4target
BethanecholMuscarinic acetylcholine receptor M5target
MethacholineMuscarinic acetylcholine receptor M3target
MethacholineMuscarinic acetylcholine receptor M2target
MethacholineMuscarinic acetylcholine receptor M1target
MethacholineMuscarinic acetylcholine receptor M4target
MethacholineMuscarinic acetylcholine receptor M5target
MethacholineSolute carrier family 22 member 5transporter
MethylnaltrexoneMu-type opioid receptortarget
MethylnaltrexoneKappa-type opioid receptortarget
Nitrous acidHemoglobin subunit alphatarget
Nitrous acidHemoglobin subunit betatarget
Nitrous acidMyoglobintarget
AmmoniaGlutaminase liver isoform, mitochondrialenzyme
AmmoniaGlutamine synthetaseenzyme
AmmoniaCarbamoyl-phosphate synthase [ammonia], mitochondrialenzyme
TridihexethylMuscarinic acetylcholine receptor M1target
TridihexethylMuscarinic acetylcholine receptor M2target
TridihexethylMuscarinic acetylcholine receptor M3target
CisplatinDNAtarget
CisplatinCanalicular multispecific organic anion transporter 2transporter
CisplatinMultidrug resistance-associated protein 5transporter
CisplatinCanalicular multispecific organic anion transporter 1transporter
CisplatinSolute carrier family 22 member 2transporter
CisplatinHigh affinity copper uptake protein 1transporter
CisplatinProbable low affinity copper uptake protein 2transporter
CisplatinMultidrug resistance-associated protein 6transporter
CisplatinCopper-transporting ATPase 2transporter
CisplatinCopper-transporting ATPase 1transporter
CisplatinProstaglandin G/H synthase 2enzyme
CisplatinMyeloperoxidaseenzyme
CisplatinXanthine dehydrogenase/oxidaseenzyme
CisplatinArylamine N-acetyltransferaseenzyme
CisplatinCytochrome P450 2C9enzyme
CisplatinCytochrome P450 2B6enzyme
CisplatinCholinesteraseenzyme
CisplatinCytochrome P450 4A11enzyme
CisplatinATP-binding cassette sub-family G member 2transporter
CisplatinGlutathione S-transferase theta-1enzyme
CisplatinMetallothionein-1Aenzyme
CisplatinMetallothionein-2enzyme
CisplatinSuperoxide dismutase [Cu-Zn]enzyme
CisplatinGlutathione S-transferase Penzyme
CisplatinNAD(P)H dehydrogenase [quinone] 1enzyme
CisplatinGlutathione S-transferase Mu 1enzyme
CisplatinDNA-3-methyladenine glycosylasetarget
CisplatinAlpha-2-macroglobulintarget
CisplatinSerum albumincarrier
CisplatinSerotransferrintarget
CisplatinCopper transport protein ATOX1target
IsopropamideMuscarinic acetylcholine receptor M3target
IsopropamideMuscarinic acetylcholine receptor M4target
GhavamiolAlpha-mannosidase 2target
N-Dodecyl-N,N-Dimethyl-3-Ammonio-1-PropanesulfonatePenton proteintarget
N-Dodecyl-N,N-Dimethyl-3-Ammonio-1-PropanesulfonateInsulin-like growth factor Itarget
N-Dodecyl-N,N-Dimethyl-3-Ammonio-1-PropanesulfonateAmine oxidase [flavin-containing] Btarget
DodecyltrimethylammoniumTyrosine-protein phosphatase non-receptor type 11target
TetramethylammoniumUDP-glucose 4-epimerasetarget
DidecyldimethylammoniumCyclopropane mycolic acid synthase 2target
DidecyldimethylammoniumPhospholipid membranetarget
ThonzoniumV-type proton ATPase subunit C 1target
OtiloniumCytochrome P450 3A4enzyme
NitroprussideAtrial natriuretic peptide receptor 1target
NitroprussideCytochrome P450 1A1enzyme
CyanamideCarbonic anhydrase 2target
CyanamideCathepsin Ktarget
Calcium carbimideAldehyde dehydrogenase family 3 member B2target
Calcium carbimideCatalaseenzyme
Potassium nitratePotassium voltage-gated channel subfamily H member 2target
Potassium nitratePentaerythritol tetranitrate reductaseenzyme
Potassium nitrateMucin-1transporter
Chromic nitrateSerotransferrincarrier
Chromic nitrateCytochrome b5target
AzvudineATP-binding cassette sub-family G member 2target
AzvudineCanalicular multispecific organic anion transporter 1target
AzvudineP-glycoprotein 1target