- Nitrogen Compounds
- Accession Number
Inorganic compounds that contain nitrogen as an integral part of the molecule.
Drug Drug Description Choline A nutrient found in a wide variety of vitamins including pre-natal formulations. Succinylcholine A depolarizing skeletal muscle relaxant used adjunctly to anesthesia and for skeletal muscle relaxation during intubation, mechanical ventilation, and surgical procedures. Oxyphenonium For the treatment of visceral spasms Nitroprusside A direct acting vasodilator used to treat hypertension, to induce controlled hypotension to reduce postoperative bleeding, and to manage acute heart failure. Carbamoylcholine A direct acting miotic agent administered ophthalmically to decrease intraocular pressure after cataract surgery, and to induce miosis during surgery. Metocurine iodide For use as an anesthesia adjunct to induce skeletal muscle relaxation and to reduce the intensity of muscle contractions in convulsive therapy. Nitric Oxide A vasodilating agent used in the treatment of hypoxic respiratory failure in premature neonates. Gallamine triethiodide A nondepolarizing nerve blocker used in addition to anesthesia to cause skeletal muscle relaxation. Tridihexethyl Used as an adjunct in the treatment of peptic ulcer disease and in Acquired nystagmus Cisplatin A platinum based chemotherapy agent used to treat various sarcomas, carcinomas, lymphomas, and germ cell tumors. Levocarnitine A quaternary ammonium compound used to treat carnitine deficiency or to stimulate gastric and pancreatic secretions in hyperlipoproteinemia. Propantheline An antimuscarinic agent used to treat urinary incontinence, hyperhidrosis, as well as cramps and spasms of the stomach, intestines, and bladder. Methantheline For the treatment of peptic ulcer disease, irritable bowel syndrome, pancreatitis, gastritis, biliary dyskinesia, pylorosplasm, and reflex neurogenic bladder in children. Hexafluronium Used as an adjunct with succinylcholine (or suxamethonium chloride) to prolong muscle relaxation and to prevent succinylcholine-induced muscle fasciculations. Demecarium For the topical treatment of chronic open-angle glaucoma. Glycopyrronium An anticholinergic agent used to treat hyperhidrosis, severe drooling, COPD, used with other medications to treat ulcers, and used in anesthesia. Edrophonium A cholinesterase inhibitor used to diagnose and evaluate myasthenia gravis. Bethanechol A muscarinic agonist used to treat postoperative and postpartum nonobstructive functional urinary retention and neurogenic atony of the bladder with retention. Ambenonium A cholinesterase inhibitor that targets both muscarinic and nicotinic receptors indicated for the treatment of myasthenia gravis. Bretylium A norepinephrine release inhibitor used for the prophylaxis and therapy of ventricular fibrillation, as well as the treatment of life-threatening ventricular arrhythmias. Tubocurarine Tubocurarine is a non-depolarizing neuromuscular blocking agent and the first identified curare alkaloid. Curare is one of the names used to describe plant-derived poisons used by indigenous South Americans to... Decamethonium For use as a skeletal muscle relaxant Oxtriphylline A bronchodilator used for the treatment of asthma, bronchitis, COPD, and emphysema. Metocurine Metocurine is a muscle relaxant. Neostigmine A cholinesterase inhibitor used in the symptomatic treatment of myasthenia gravis by improving muscle tone. Choline magnesium trisalicylate Choline magnesium trisalicylate is used to reduce pain and inflammation caused by conditions such as arthritis. This medication is also used to treat fever in adults. Embutramide Not Available Amyl Nitrite A fast acting vasodilator used for rapid relief of angina pectoris. Erythrityl tetranitrate For the prevention of angina. Isopropamide For the treatment of a wide range of gastrointestinal disorders, including such conditions as peptic ulcer, gastritis, hyperchlorhydria, functional diarrhea, irritable or spastic colon, pyloroduodenal irritability, pylorospasm, acute nonspecific gastroenteritis,... Cetrimonium A compound that can be used as a topical antiseptic. Platelet Activating Factor Not Available Ghavamiol Not Available N-Dodecyl-N,N-Dimethyl-3-Ammonio-1-Propanesulfonate Not Available Cyanamide A cyanide compound which has been used as a fertilizer, defoliant and in many manufacturing processes. It often occurs as the calcium salt, sometimes also referred to as cyanamide. The... N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction. Butyrylthiocholine A sulfur-containing analog of butyrylcholine which is hydrolyzed by butyrylcholinesterase to butyrate and thiocholine. It is used as a reagent in the determination of butyrylcholinesterase activity. [PubChem] NOV-002 Investigated for use/treatment in breast cancer, lung cancer, and ovarian cancer. C31G Investigated for use/treatment in contraception, HIV infection, and prevention of stdis. NCX 701 Investigated for use/treatment in pain (acute or chronic). Perifosine Investigated for use/treatment in solid tumors, multiple myeloma, leukemia (unspecified), lung cancer, and brain cancer. Nitrous oxide An inhalatory gas used as an adjunct to improve oxygenation and reduce the need for extracorporeal membrane oxygenation in certain neonates with hypoxic respiratory failure. Methacholine A parasympathomimetic bronchoconstrictor used to diagnose bronchial hyperreactivity in subjects who do not have clinically apparent asthma. Betaine A methyl group donor used for the treatment of homocystinuria to decrease elevated homocysteine blood levels. Ammonium chloride Expectorant in cough syrups. The ammonium ion (NH4+) in the body plays an important role in the maintenance of acid-base balance. The kidney uses ammonium (NH4+) in place of sodium... Prussian blue A chelating agent used to reduce the extent of systemic contamination with radioactive cesium and/or radioactive or non-radioactive thallium. Methylnaltrexone A μ-opioid antagonist used for the treatment of opioid-induced constipation in palliative patients that are inadequately responding to laxative therapy. Tetraethylammonium Tetraethylammonium is an experimental drug with no approved indication. Acetylcarnitine Acetylcarnitine is not approved for any indication in the United states and Canada, but it is approved and indicated in Italy for cerebrovascular disorders, mental function disorders, peripheral nerve disorders,... Hexamethonium A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been... Miltefosine An antileishmanial agent used to treat leishmaniasis, a group of disease caused by parasites of the Leishmania type. Nitrous acid An iron binder used to reverse life-threatening acute cyanide poisoning. Nicorandil Indicated for the prevention and treatment of chronic stable angina pectoris and reduction in the risk of acute coronary syndromes. Butylscopolamine An antispasmodic and anticholinergic agent used for the symptomatic treatment of abdominal cramping and pain. Ferric ammonium citrate Not Annotated Thonzonium A cationic surfactant used to disperse exudate and cellular debris, as well as enhance the penetration of antimicrobials. Silver nitrate Silver nitrate is an inorganic compound with the chemical formula AgNO3. In its solid form, silver nitrate is coordinated in a trigonal planar arrangement. It is often used as a... Potassium nitrate A medication used to cauterize small wounds, remove granulation tissue, warts, and verrucae, and treat tooth sensitivity. Benzalkonium An antiseptic agent used as a preservative in medications or as a disinfectant in cleaning products. Ammonia Indicated for use as a smelling salt to treat or prevent fainting. (when radiolabelled) Indicated for diagnostic PET imaging of the myocardium under rest or pharmacologic stress conditions to evaluate... Benzethonium A medication used as to clean hands and clean minor cuts and scrapes. Light green SF yellowish Light green SF yellowish is a green triarylmethane dye that is used in the preparation of the staining solution which is widely used as a counterstain. It is used in... Brilliant green cation An ingredient used in topical medications to prevent infections of the umbilical cord. Ichthammol Ichthammol is also referred to as ammonium bituminosulfonate or ammonium bituminosulphonate. It is an ammonium salt of dark sulfonated shale oil (bituminous schists) produced via distillation of the oil followed... Cocamidopropyl betaine Cocamidopropyl betaine is a mixture of closely related organic compounds derived from coconut oil and dimethylaminopropylamine that typically acts as an amphoteric surfactant in cosmetics and personal care products. It... Cetalkonium An antiseptic used as a preservative or to treat certain topical infections. Domiphen Anti-infective (topical), it is used for the treatment of Acute Infectious Dental Diseases and other conditions. Indium Indium has been used in trials studying the basic science of Clear Cell Renal Cell Carcinoma. CHS-828 CHS-828 has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific. Methylbenactyzium Not Annotated Benzododecinium Benzododecinium is used as an antiseptic/disinfectant compound. It has been marketed as a tincture for antiseptic product for wounds in the Czech Republic. Mercuric amidochloride Not Annotated Valethamate Not Annotated Otilonium Not Annotated Emepronium Not Annotated Benzoxonium Not Annotated Gallamine Not Annotated Aminoethyl nitrate Not Annotated Alcuronium A non-depolarizing skeletal muscle relaxant similar to tubocurarine. It is used as an anesthesia adjuvant. Penthienate Not Annotated Decamethoxine Not Annotated Trolnitrate Not Annotated Dioctyldimonium Not Annotated Choline salicylate The oral gel is indicated for the relief of pain and discomfort of common mouth ulcers, cold sores, denture sore spots, infant teething and mouth ulcers, and sore spots due... Nitrate Not Annotated Trabodenoson Trabodenoson has been used in trials studying the treatment of Ocular Hypertension (OHT) and Primary Open-Angle Glaucoma (POAG). Distearyldimonium Not Annotated Chromic nitrate Indicated for use as a supplement to intravenous solutions given for total parenteral nutrition (TPN), to maintain chromium serum levels and to prevent depletion of endogenous stores and subsequent deficiency... Platinum Platinum is under investigation for the treatment of Metastatic Breast Cancer, Non-small Cell Lung Cancer, Gastric Large Cell Neuroendocrine Carcinoma, Colorectal Large Cell Neuroendocrine Carcinoma, and Pancreatic Large Cell Neuroendocrine... Didecyldimethylammonium A disinfectant and microbicidal agent used in a variety of products. Citicoline Citicoline is a donor of choline in biosynthesis of choline-containing phosphoglycerides. It has been investigated for the treatment, supportive care, and diagnosis of Mania, Stroke, Hypomania, Cocaine Abuse, and Bipolar... Betaine aldehyde Not Available Dodecyltrimethylammonium Not Available Lauryldimethylbetaine Not Available Tetramethylammonium Not Available Cetyltrimethylammonium naproxenate Not Annotated Fluorocholine F-18 Not Annotated Sodium nitrate Not Annotated Nitric acid Not Annotated NCX-1000 NCX-1000 is under investigation in clinical trial NCT00414869 (Preliminary Efficacy and Tolerability of NCX-1000 After Repeated Oral Doses in Patients With Elevated Portal Pressure). Azvudine Azvudine is under investigation in clinical trial NCT04668235 (Study on Safety and Clinical Efficacy of AZVUDINE in COVID-19 Patients (Sars-cov-2 Infected)). Ethyl nitrite Not Annotated
- Drugs & Drug Targets