Primary Amyloidosis

Also known as: Primary Systemic Amyloidosis (AL) / Primary Systemic (AL) Amyloidosis / Primary Systemic Amyloidosis / Primary Amyloidosis of Light Chain Type / Amyloid Light Chain (AL) Amyloidosis / AL Amyloidosis / Light Chain (AL) Amyloidosis / Light-Chain Amyloidosis / Systemic Light Chain Disease / Amyloid light-chain amyloidosis / Immunoglobulin Light-chain Amyloidosis / Amyloid light-chain amyloidosis (disorder) / Immunoglobulin deposition disease (morphologic abnormality)

DrugDrug NameDrug Description
DB09331DaratumumabA CD38-directed cytolytic antibody used alone or as an adjunct drug in the treatment of multiple myeloma and light chain amyloidosis.
DB00480LenalidomideA thalidomide derivative used to treat multiple myeloma and anemia in low to intermediate risk myelodysplastic syndrome.
DB01041ThalidomideA medication used to treat cancers, particularly newly diagnosed multiple myeloma, and erythema nodosum leprosum.
DrugDrug NamePhaseStatusCount
DB01234Dexamethasone0Withdrawn1
DB11942Selinexor0Withdrawn1
DB17492Anselamimab1Completed3
DB00188Bortezomib1Active Not Recruiting1
DB00188Bortezomib1Terminated1
DB16741Bortezomib D-mannitol1Active Not Recruiting1
DB16741Bortezomib D-mannitol1Terminated1
DB00531Cyclophosphamide1Active Not Recruiting1
DB01234Dexamethasone1Active Not Recruiting1
DB01234Dexamethasone1Completed1
DB01234Dexamethasone1Recruiting1
DB01234Dexamethasone1Terminated3
DB00619Imatinib1Completed1
DB14811Isatuximab1Active Not Recruiting1
DB09570Ixazomib1Completed1
DB09570Ixazomib1Recruiting1
DB16627Melphalan flufenamide1Terminated1
DB08910Pomalidomide1Terminated1
DB01268Sunitinib1Completed1
DB11581Venetoclax1Recruiting1
DB11581Venetoclax1Terminated1
DB15719Belantamab mafodotin1 / 2Recruiting1
DB06769Bendamustine1 / 2Recruiting1
DB16414Birtamimab1 / 2Completed1
DB00531Cyclophosphamide1 / 2Completed1
DB00091Cyclosporine1 / 2Completed1
DB09331Daratumumab1 / 2Completed1
DB09331Daratumumab1 / 2Recruiting2
DB01234Dexamethasone1 / 2Completed2
DB01234Dexamethasone1 / 2Recruiting2
DB01073Fludarabine1 / 2Completed1
DB09570Ixazomib1 / 2Completed1
DB09570Ixazomib1 / 2Recruiting1
DB00688Mycophenolate mofetil1 / 2Completed1
DB08910Pomalidomide1 / 2Completed1
DB08910Pomalidomide1 / 2Recruiting1
DB11581Venetoclax1 / 2Recruiting2
DB01118Amiodarone2Terminated1
DB17492Anselamimab2Completed1
DB15719Belantamab mafodotin2Recruiting1
DB06769Bendamustine2Completed1
DB06769Bendamustine2Withdrawn1
DB16414Birtamimab2Completed1
DB16414Birtamimab2Terminated2
DB00188Bortezomib2Completed4
DB16741Bortezomib D-mannitol2Completed3
DB14086Cianidanol2Completed1
DB00515Cisplatin2Completed1
DB00531Cyclophosphamide2Completed4
DB09331Daratumumab2Completed1
DB09331Daratumumab2Recruiting3
DB01234Dexamethasone2Active Not Recruiting2
DB01234Dexamethasone2Completed7
DB01234Dexamethasone2Recruiting2
DB00997Doxorubicin2Completed1
DB00254Doxycycline2Completed1
DB03823Epigallocatechin2Completed1
DB12116Epigallocatechin gallate2Completed1
DB12116Epigallocatechin gallate2Terminated1
DB00005Etanercept2Completed1
DB00773Etoposide2Completed1
DB00099Filgrastim2Completed1
DB14811Isatuximab2Active Not Recruiting1
DB14811Isatuximab2Recruiting1
DB14811Isatuximab2Withdrawn1
DB09570Ixazomib2Active Not Recruiting1
DB00480Lenalidomide2Completed2
DB00742Mannitol2Completed1
DB01042Melphalan2Completed3
DB08910Pomalidomide2Completed1
DB08910Pomalidomide2Recruiting3
DB11132Silicon dioxide2Completed1
DB09036Siltuximab2Active Not Recruiting1
DB01041Thalidomide2Completed1
DB11581Venetoclax2Active Not Recruiting1
DB17492Anselamimab3Active Not Recruiting2
DB16414Birtamimab3Recruiting1
DB16414Birtamimab3Terminated1
DB00188Bortezomib3Active Not Recruiting2
DB00188Bortezomib3Completed1
DB00188Bortezomib3Recruiting1
DB00188Bortezomib3Terminated1
DB16741Bortezomib D-mannitol3Recruiting1
DB16741Bortezomib D-mannitol3Terminated1
DB00531Cyclophosphamide3Active Not Recruiting2
DB00531Cyclophosphamide3Recruiting1
DB09331Daratumumab3Recruiting1
DB01234Dexamethasone3Active Not Recruiting2
DB01234Dexamethasone3Completed2
DB01234Dexamethasone3Recruiting1
DB00099Filgrastim3Terminated1
DB09148Florbetaben F-183Recruiting1
DB06205Hyaluronidase (human recombinant)3Recruiting1
DB00888Mechlorethamine3Recruiting1
DB01042Melphalan3Completed3
DB01042Melphalan3Terminated1
DB00188BortezomibNot AvailableRecruiting1
DB01008BusulfanNot AvailableCompleted1
DB00958CarboplatinNot AvailableCompleted1
DB00262CarmustineNot AvailableCompleted1
DB00531CyclophosphamideNot AvailableCompleted1
DB00091CyclosporineNot AvailableCompleted2
DB09331DaratumumabNot AvailableRecruiting2
DB01234DexamethasoneNot AvailableRecruiting1
DB00773EtoposideNot AvailableCompleted1
DB09148Florbetaben F-18Not AvailableRecruiting1
DB01073FludarabineNot AvailableCompleted2
DB00529FoscarnetNot AvailableCompleted1
DB01004GanciclovirNot AvailableCompleted1
DB06205Hyaluronidase (human recombinant)Not AvailableRecruiting1
DB01042MelphalanNot AvailableCompleted1
DB00688Mycophenolate mofetilNot AvailableCompleted2
DB08910PomalidomideNot AvailableRecruiting1
DB04572ThiotepaNot AvailableCompleted1
DB01610ValganciclovirNot AvailableCompleted1
DB11581VenetoclaxNot AvailableRecruiting1