NCT03712280
MNK6106 for Liver Disease (Hepatic Cirrhosis) That in the Past Has Affected the Brain (Hepatic Encephalopathy) treatment 2 completed NCT01597102
Cerebrovascular Autoregulation During and After Liver Transplantation No drug interventions Not Available Not Available unknown_status NCT02464124
Nitazoxanide Plus Lactulose Versus Lactulose Alone Treatment of Hepatic Encephalopathy treatment 2 / 3 unknown_status NCT00553423
Lactulose for the Prevention of Hepatic Encephalopathy in Cirrhotic Patients With Upper Gastrointestinal Hemorrhage prevention 3 unknown_status NCT06425380
Pilot Open-Label Trial of Resistant Potato Starch in Patients with Cirrhosis and Overt Hepatic Encephalopathy No drug interventions treatment 2 recruiting NCT02401490
Albumin Infusion Effects in Mortality in Patients With Cirrhosis and Hepatic Encephalopathy treatment 4 unknown_status NCT01494064
Monitoring of Encephalopathy in Cirrhotic Patients Admitted in Intensive Care No drug interventions Not Available Not Available completed NCT04862221
TReatment for ImmUne Mediated PathopHysiology treatment 2 recruiting NCT06072521
Efficacy of Lactoferrin as an Adjunct Therapy in Patients With Hepatic Encephalopathy supportive_care 2 not_yet_recruiting NCT04664621
HepQuant to Predict Hepatic Encephalopathy After TIPS No drug interventions diagnostic Not Available withdrawn NCT01356121
Trial Comparing Sedation for Endoscopy With Propofol Versus Midazolam in Cirrhotics treatment 4 unknown_status NCT00281502
The Role of Bacterial Overgrowth and Delayed Intestinal Transit in Hepatic Encephalopathy treatment 2 unknown_status NCT05206487
Hepatic Encephalopathy Prevention With Polydextrose After TIPS: Pilot Study (POEME) No drug interventions prevention Not Available recruiting NCT03961087
Coenzyme Q10 and Meclofenoxate in Hepatic Encephalopathy treatment Not Available unknown_status NCT05669651
Explore the Efficacy and Safety of FMT With Different Bacterial Doses in the Treatment of Hepatic Encephalopathy No drug interventions treatment Not Available active_not_recruiting NCT05421351
Immune Profile, Neuronal Dysfunction, Metabolomics and Ammonia in Therapeutic Response of HE in ACLF No drug interventions Not Available Not Available recruiting NCT01603953
Bioelectrical Impedance Vector Analysis in Cirrhotic Patients No drug interventions Not Available Not Available completed NCT03306498
Plasma Free Amino Acids in Patients With Hepatic Encephalopathy Not Available Not Available unknown_status NCT02488993
Real World Outcomes Study of Hepatic Encephalopathy Patients' Experience on Rifaximin (PROSPER) No drug interventions Not Available Not Available completed NCT01008293
Effect of Probiotics in Treatment of Minimal Hepatic Encephalopathy (MHE) and Health Related Quality of Life treatment 2 / 3 completed NCT02858778
Timing of Acute Palliative Care Consultation in Critically Ill Patients No drug interventions supportive_care Not Available unknown_status NCT05376488
Effect of Brief Dietary Intervention on Ammonia Levels No drug interventions supportive_care Not Available completed NCT06328088
Vegetarian Versus Non Vegetarian Based Diet in the Recurrence of Hepatic Encephalopathy in Patients With Cirrhosis: An Open Label Pilot Study No drug interventions Not Available Not Available recruiting NCT06201988
Revealing Engagement Patterns Among Hepatic Encephalopathy Patients No drug interventions Not Available Not Available not_yet_recruiting NCT03152188
Oral Fecal Transplant in Cirrhosis No drug interventions prevention 1 completed NCT00914056
A Study of Controlled Lactulose Withdrawal diagnostic Not Available completed NCT05140837
Early Diagnosis and Timely Treatment of Cirrhotic Patients With Minimal Hepatic Encephalopathy (CHESS-NCRCID 2106) No drug interventions Not Available Not Available recruiting NCT02163837
Effect of Rifaximine on Sleep Disorders in Patients Suffering From Hepatic Encephalopathy treatment Not Available completed NCT01283152
Efficacy Study of Polyethylene Glycol 3350-electrolyte Solution (GoLYTELY®) Versus Lactulose in Patients With Hepatic Encephalopathy. treatment Not Available completed NCT00955500
Effects of Proteins in Patients With Cirrhosis and Prior Hepatic Encephalopathy No drug interventions prevention 4 completed NCT05786859
The Efficacy and Safety of Rifaximin Treatment treatment 0 recruiting NCT00375375
Effect of Lactulose on Minimal Hepatic Encephalopathy and Health-Related Quality of Life treatment 4 completed NCT01223742
Oral Acetyl-L-Carnitine Therapy Reduces Fatigue In Hepatic Encephalopathy No drug interventions Not Available Not Available completed NCT04155099
Investigational Microbiota Restoration Therapeutic for Hepatic Encephalopathy No drug interventions treatment 2 terminated NCT02427906
Effect of Transjugular Intrahepatic Portosystemic Shunt on Gut Microbiota in Cirrhotic Patients No drug interventions Not Available Not Available unknown_status NCT06248736
Description of Lactulose Administration by Balloon Rectal Tube in Severe Hepatic Encephalopathy No drug interventions Not Available Not Available recruiting NCT01842113
Quality of Life and Nutritional Improvements in Cirrhotic Patients treatment 4 terminated NCT03100513
PEG (Polyethylene Glycol)Versus Lactulose For Treatment Of Overt Hepatic Encephalopathy treatment 4 unknown_status NCT04014413
Safety and Efficacy of Fecal Microbiota Transplantation No drug interventions treatment Not Available recruiting NCT02017119
Comparison Between Lactulose and Lactulose-Paraffin in Cirrhotic Patients treatment 2 completed NCT01846819
Factors Associated With End Stage Liver Disease No drug interventions Not Available Not Available terminated NCT01559519
Post Transjugular Intrahepatic Portosystemic Shunt (Tips) Albumine Infusion to Prevent Hepatic Encephalopathy prevention 4 completed NCT04940416
Eye Movement Testing for Diagnosing Encephalopathy in Patients With Liver Disease No drug interventions Not Available Not Available terminated NCT04816916
Efficacy and Safety of AXA1665 in Cirrhotic Subjects With Prior Overt Hepatic Encephalopathy No drug interventions treatment 2 terminated NCT04238416
Intravenous Branched Chain Amino Acids for Hepatic Encephalopathy in ACLF treatment 1 completed NCT05754996
Comparing Nifuroxazide Plus Lactulose With Lactulose Alone in the Treatment of Hepatic Encephalopathy treatment 3 recruiting NCT00839358
Effect of Midodrine and Albumine in the Prevention of Complications in Cirrhotic Patients Awaiting Liver Transplantation prevention 4 completed NCT02613858
Minimal HePatic Encephalopathy Among CiRrhotics. A Cross SEctional, Clinico-EpidEmiological, Multi-Centre, Study in Patients of PakisTan No drug interventions Not Available Not Available completed NCT01846663
Efficacy, Safety, And Pharmacokinetics Of Rifaximin In Subjects With Severe Hepatic Impairment And Hepatic Encephalopathy treatment 4 terminated NCT05279586
Secondary Prophylaxis of Hepatic Encephalopathy in Cirrhotic Patients other 0 unknown_status NCT04317222
Early Postoperative CRRT After Liver Transplantation in ACLF Patients With Overt HE No drug interventions treatment Not Available unknown_status NCT02692430
The International Imaging Registry in Liver Cirrhosis (BAVENO-VI SPSS GROUP). No drug interventions Not Available Not Available unknown_status NCT05297448
Study to Assess Rifaximin Soluble Solid Dispersion (SSD) for the Delay of Encephalopathy Decompensation in Cirrhosis prevention 3 active_not_recruiting NCT00986648
A Multi-Center Group to Study Acute Liver Failure in Children No drug interventions Not Available Not Available completed NCT00424957
Brain Energy Metabolism in Patients With Chronic Liver Disease and Impaired Central Nervous System No drug interventions Not Available Not Available completed NCT03585257
HEAL STUDY (Hepatic Encephalopathy and Albumin Study) treatment 2 completed NCT00686920
Safety and Tolerability Study of Rifaximin in Participants With a History of Hepatic Encephalopathy prevention 3 completed NCT02154282
iPod Games in Hepatic Encephalopathy No drug interventions treatment Not Available completed NCT04058327
A Study of MHE in Patients With Liver Diseases No drug interventions Not Available Not Available completed NCT05539027
Efficacy of L-Ornithine L-Aspartate (LOLA) as an Adjunct to Branched Chain Amino Acids (BCAA) Enriched Solutions on Clinical Outcomes in ICU Patients With Hepatic Encephalopathy treatment 4 recruiting NCT05033327
Feasibility of an App-based Nutrition & Exercise Program in Cirrhosis No drug interventions treatment Not Available completed NCT06367127
Utility of the Clamping Bean Test (CBT) for Covert Hepatic Encephalopathy Screening No drug interventions Not Available Not Available enrolling_by_invitation NCT01923376
Hepatic Encephalopathy: Lactulose or Polyethylene Glycol (H.E.L.P.) treatment Not Available withdrawn NCT04415294
Flicker App for Minimal Hepatic Encephalopathy No drug interventions Not Available Not Available unknown_status NCT04128462
MNK-6105 for Patients With Cirrhosis and High Ammonia Levels Affecting Brain Function treatment 3 withdrawn NCT01798329
ETOS: Minimal Hepatic Encephalopathy in Childhood and Young Adult: epidemiOlogical Study and Pilot Interventional Study No drug interventions treatment 3 unknown_status NCT05229289
Efficacy and Safety of Fecal Microbiota Transplant for Secondary Prophylaxis of Hepatic Encephalopathy No drug interventions treatment Not Available unknown_status NCT00999167
A Study of Safety and Efficacy of HPN-100 in Subjects With Cirrhosis and Episodic Hepatic Encephalopathy treatment 2 completed NCT01113567
Effect of Lactose in Patients With Chronic Liver Disease and Minimal Hepatic Encephalopathy No drug interventions treatment Not Available terminated NCT04436601
Polyethylene Glycol Versus Lactulose on Hepatic Encephalopathy in Patients With Cirrhosis;(PEGHE Trial) treatment 4 recruiting NCT03493204
Tackling 30-day Readmissions in Patients With Cirrhosis: The SALTYFOOD Trial No drug interventions treatment Not Available completed NCT00655304
The Effect of Prometheus (R) Liver Support Dialysis on Cerebral Metabolism in Acute Liver Failure No drug interventions treatment Not Available completed NCT01178372
Secondary Prophylaxis of Hepatic Encephalopathy in Cirrhosis Not Available 4 unknown_status NCT06179368
Throid Dysfunction in Liver Failure and Its Eddects Upon Outcome No drug interventions Not Available Not Available recruiting NCT05466669
Prediction of Post-TIPS Hepatic Encephalopathy in Patients With Liver Cirrhosis No drug interventions Not Available Not Available recruiting NCT01556646
Effect of Tolvaptan on Cognitive Function in Cirrhosis treatment 3 completed NCT01842581
The Safety/Efficacy of Rifaximin With/Without Lactulose in Participants With A History of Recurrent Hepatic Encephalopathy treatment 4 completed NCT00986895
A Study of Glyceryl Tri-(4-phenylbutyrate) Administered Orally as a Single Dose, and Twice Daily for Seven Consecutive Days to Subjects With Hepatic Impairment With Cirrhosis and to a Control Group treatment 1 completed NCT04096014
Late Evening and Early Morning Protein Supplement to Reduce Readmissions for Hepatic Encephalopathy No drug interventions prevention Not Available recruiting NCT01041755
Efficacy of L-Ornithine L-Aspartate in Acute Hepatic Encephalopathy. treatment 4 completed NCT01882855
Effect of Music on Attention and Prospective Memory in Hepatic Encephalopathy No drug interventions Not Available Not Available withdrawn NCT01446523
S. Endotoxin, Inflammatory Mediators and MRS Before and After Treatment in MHE treatment Not Available completed NCT02177708
Quantitative Determination of Brain Water Content in Patients During and After Hepatic Encepalopathy No drug interventions Not Available Not Available unknown_status NCT00298038
A 6-month Efficacy, Safety, and Tolerability Study of Rifaximin In Preventing Hepatic Encephalopathy prevention 3 completed NCT01175538
Primary Prophylaxis of Hepatic Encephalopathy in Patients With Cirrhosis treatment 4 unknown_status NCT04073290
Prevention of Post-TIPS Hepatic Encephalopathy by Administration of Rifaximin and Lactulose prevention 4 unknown_status NCT01847651
Brain Muscle Axis During Treatment of Hepatic Encephalopathy With L-ornithine L-aspartate No drug interventions treatment 4 completed NCT05070351
Deprescribing Proton Pump Inhibitors to Reduce Post-TIPS Hepatic Encephalopathy No drug interventions prevention 1 / 2 recruiting NCT04161053
Efficacy and Safety of Nitazoxanide in Preventing Recurrence of Hepatic Encephalopathy prevention 3 recruiting NCT06538077
BCAA vs. Rifaximin in Patients With Cirrhosis for Secondary Prophylaxis of HE treatment Not Available not_yet_recruiting NCT02377947
A Retrospective, Open-label, Uncontrolled Cohort Study to Assess the Effectiveness and Safety of Lactulose Retention Enema in the Treatment of Cirrhotic Patients With Grade 3 or 4 (West Haven Criteria) Hepatic Encephalopathy (HE) [The RETRO Study] No drug interventions Not Available Not Available completed NCT01110447
Secondary Prophylaxis of Hepatic Encephalopathy With a Probiotic Preparation prevention 2 / 3 completed NCT02636647
Fecal Transplant in Recurrent Hepatic Encephalopathy No drug interventions other 1 completed NCT03796598
FMT in Cirrhosis and Hepatic Encephalopathy No drug interventions other 1 / 2 completed NCT01878305
Neuromonitoring of Hepatic Encephalopathy No drug interventions Not Available Not Available completed NCT05128305
Integrated Traditional Chinese and Clinical Medicine for Chronic Hepatitis B and Its Complication No drug interventions treatment 3 unknown_status NCT04131205
Role of MRI in Detection of Minimal Hepatic Encephalopathy No drug interventions Not Available Not Available unknown_status NCT01097811
Comparison Between Erythromycin and Neomycin Treatment of Hepatic Encephalopathy treatment Not Available unknown_status NCT03987893
PEG3350 in ACLF With Hepatic Encephalopathy treatment 4 unknown_status NCT01099293
Cerebrovascular Reactivity in Hepatic Encephalopathy No drug interventions Not Available Not Available completed NCT01777971
The Effect of a Large-volume Paracentesis on Fatigue, Sleep, and Quality of Life in Cirrhosis No drug interventions Not Available Not Available withdrawn NCT01722578
L-ornithine L-aspartate in Overt Hepatic Encephalopathy treatment 4 completed NCT02026609
Glutamine Challenge as Predictor of Hepatic Encephalopathy After Transjugular Intrahepatic Portosystemic Shunt (TIPS) No drug interventions Not Available Not Available terminated NCT00597909
Efficacy and Safety Study of Ammonul® in Patients With Grade 3 or 4 Hepatic Encephalopathy treatment 2 terminated NCT01434056
Prediction of Mortality in Patients Waiting for Liver Transplantation Through Brain Magnetic Resonance Imaging No drug interventions Not Available Not Available unknown_status NCT05772585
Characterization of Metabolomic Fingerprints in Patients With Acute Liver Failure and Acute-on-chronic Liver Failure With Hepatic Encephalopathy No drug interventions Not Available Not Available withdrawn NCT03267615
VICIS - Vienna Cirrhosis Study No drug interventions Not Available Not Available recruiting NCT03586115
Minimal Hepatic Encephalopathy in Hereditary Hemorrhagic Telangiectasian No drug interventions Not Available Not Available completed NCT04899115
VE303 for Treatment of Hepatic Encephalopathy (HE) treatment 2 completed NCT04675775
The BRAINFOOD Trial to Prevent Recurrent Hepatic Encephalopathy. No drug interventions treatment Not Available completed NCT06075875
Vegetable Proteins Versus Mixed Animal Proteins on the Outcome of Hepatic Encephalopathy No drug interventions supportive_care Not Available not_yet_recruiting NCT01151475
Cerebral Oxygen, Blood Flow and Ammonia Uptake in Patients With Cirrhosis and an Acute Episode of Hepatic Encephalopathy (HE) No drug interventions Not Available Not Available completed NCT00740142
Efficacy of Combined Oral L-ornithine-L-aspartate and Lactulose in Patients With Hepatic Encephalopathy treatment 4 completed NCT03372499
Diet Management on Hepatic Encephalopathy of Patients With Variceal Bleeding After Intrahepatic Portosystemic Shunt Creation No drug interventions treatment Not Available unknown_status NCT01846806
The Role of Bacterial Overgrowth and Delayed Intestinal Transit in Hepatic Encephalopathy. No drug interventions treatment Not Available terminated NCT04736836
Microbial Resistance of Rifaximin in Hepatic Encephalopathy prevention 4 completed NCT01966419
Phase 2B Efficacy/Safety of Ornithine Phenylacetate in Hospitalized Cirrhotic Patients With Hepatic Encephalopathy (STOP-HE) No drug interventions treatment 2 completed NCT02255617
Fecal Microbiota Transplantation (FMT) in the Management of Hepatic Encephalopathy (HE): a Pilot Study treatment 1 / 2 completed NCT05071716
Study to Assess Rifaximin Soluble Solid Dispersion (SSD) for the Delay of Encephalopathy Decompensation in Cirrhosis prevention 3 active_not_recruiting NCT05425316
Speech in Hepatic Encephalopathy (HE) No drug interventions Not Available Not Available completed NCT00004796
Phase II Study of Lactulose and Circadian Rhythms in Patients With Cirrhosis treatment 2 completed NCT01059396
Study on B-blockers to Prevent Decompensation of Cirrhosis With HTPortal prevention 4 completed NCT00287235
Efficacy of Albumin Dialysis to Treat Patients With Hepatic Encephalopathy Using The Molecular Adsorbent Recirculating System (MARS) No drug interventions treatment Not Available completed NCT02334163
The Effects of Nitazoxanide in Hepatic Encephalopathy treatment 2 unknown_status NCT02086825
A Randomized Comparison of Rifaximin Versus Lactulose in Hospitalized Cirrhotic Patients With Renal Failure treatment 3 withdrawn NCT00248625
N-acetylcysteine in Non-Acetaminophen Pediatric Acute Liver Failure treatment 3 completed NCT00886925
Efficacy of Albumin for Acute Encephalopathy in Patients With Cirrhosis treatment 4 completed NCT03825848
The Influence of Post-transjugular Intrahepatic Portosystemic Shunt Hepatic Encephalopathy No drug interventions treatment Not Available unknown_status NCT05566548
Role of Bilirubin Molecular Species in Hepatic Encephalopathy and Acute-on-chronic Liver Failure No drug interventions Not Available Not Available recruiting NCT04698148
Establishment of the Human Intestinal and Salivary Microbiota Biobank - Gastrointestinal Diseases No drug interventions Not Available Not Available completed NCT05433948
Diagnosing Minimal Hepatic Encephalopathy No drug interventions Not Available Not Available enrolling_by_invitation NCT05511766
Allopurinol Versus Atorvastatin to Prevent Complications of Liver Cirrhosis prevention 2 / 3 recruiting NCT03420482
Fecal Microbiota Transplant as Treatment of Hepatic Encephalopathy treatment 2 active_not_recruiting NCT03439982
Fecal Transplant for Hepatic Encephalopathy No drug interventions treatment 1 / 2 completed NCT02158182
Lactulose, L-ornithine L-aspartate, or Rifaximin Versus Placebo for Preventing Hepatic Encephalopathy in Variceal Bleeding prevention 4 completed NCT00896831
Therapeutic Efficacy of Oral L-Ornithine-L-Aspartate on Minimal Encephalopathy treatment 4 unknown_status NCT06245473
Metobolomics in the Characterisation of HE No drug interventions Not Available Not Available recruiting NCT05788627
Effectiveness of Oral Lactulose Versus Lactulose Enema in Hepatic Encephalopathy treatment 4 not_yet_recruiting NCT06052176
Hepatic Encephalopathy and Albumin Lasting Cognitive Improvement prevention 2 recruiting NCT04787276
Efficacy and Safety of E.Coli Nissle 1917 in Patients With Mild (Stage 1-2) or Minimal Hepatic Encephalopathy treatment Not Available completed NCT00931060
Effects of Branched-Chain Amino Acids on Muscle Ammonia Metabolism in Patients With Cirrhosis and Healthy Subjects No drug interventions Not Available Not Available completed NCT00305591
Brain Imaging in Patients With Chronic Liver Disease and Functional Impairment. diagnostic Not Available completed NCT04082780
Rifamycin in Minimal Hepatic Encephalopathy treatment 2 completed NCT05346029
Role of Sarcopenia and Nutritional/Physical Therapy Intervention in Post-TIPS Hepatic Encephalopathy No drug interventions prevention Not Available recruiting NCT02028429
Efficacy of Sildenafil in the Improvement of Cognition and Quality of Life in Patients With Cirrhosis of Liver. A Proof of Concept Study. treatment 1 / 2 unknown_status NCT00364689
RICE Trial: Rifaximin In Chronic Hepatic Encephalopathy - A Randomized, Controlled Trial treatment 3 terminated NCT02083367
Default Mode Network fMRI Maps as a Predictive Index of Hepatic Encephalopathy Outcome No drug interventions Not Available Not Available completed NCT04771104
The Effect of Induced Hyperammonaemia on Sleep and Melanopsin-mediated Pupillary Light Response in Patients With Liver Cirrhosis No drug interventions basic_science Not Available completed NCT05526404
Prevention of Hepatic Encephalopathy With Mobile Application Based Lactulose Titration No drug interventions prevention Not Available completed NCT00433368
Efficacy of L-Ornithine-L-Aspartate in Cirrhotics With Hepatic Encephalopathy treatment 3 completed NCT01218568
Rifaximin Plus Lactulose Versus Lactulose Alone for the Treatment of Hepatic Encephalopathy: a Double Blind Randomized Trial treatment Not Available completed NCT02048969
Treatment of Hepatic Encephalopathy With Flumazenil and Change in Cortical GABA Levels in MRS basic_science 1 / 2 withdrawn NCT02470546
Metformin Experience on Minimal Hepatic Encephalopathy treatment 4 unknown_status NCT00533910
Rifaximin in Minimal Hepatic Encephalopathy treatment Not Available completed NCT00985010
Manganese in Women With Encephalopathy No drug interventions Not Available Not Available terminated NCT05700695
Intravenous BCAA for HE in ACLF (BCAA-HE-ACLF) treatment 1 recruiting NCT06368895
Fecal Microbiota Transplantation by Oral Capsules for Hepatic Encephalopathy Treatment treatment 1 recruiting NCT06040814
Microbiota, Sarcopenia, and Hepatic Encephalopathy Change in Cirrhotic Patients Before and After Rehabilitation No drug interventions treatment Not Available recruiting NCT00558038
Safety and Efficacy of AST-120 Compared to Lactulose in Patients With Hepatic Encephalopathy treatment 2 completed NCT01773538
Diagnosis of Covert/Minimal Hepatic Encephalopathy by Means of Continuous Reaction Time Measurement diagnostic Not Available completed