- Accession Number
Compounds with BENZENE fused to AZEPINES.
Drug Drug Description Lorazepam A long-acting benzodiazepine commonly used to treat panic disorders, severe anxiety, and seizures. Temazepam A short-acting benzodiazepine commonly used to treat panic disorders, severe anxiety, and insomnia. Olanzapine An antipsychotic drug used in the management of schizophrenia, bipolar 1 disorder, and agitation associated with these disorders. Diltiazem A calcium channel blocker used to treat hypertension and to manage chronic stable angina. Clobazam A benzodiazepine used as adjunct treatment in seizures associated with Lennox-Gastaut syndrome. Alprazolam A long-acting benzodiazepine with intermediate onset commonly used to treat panic disorders and generalized anxiety in addition to anxiety associated with depression. Chlordiazepoxide A benzodiazepine used to treat the withdrawal symptoms of acute alcoholism, to treat preoperative anxiety, and to treat anxiety over a short term period. Adinazolam For the treatment of anxiety and status epilepticus. Clorazepic acid A benzodiazepine used to treat anxiety, partial seizures, and alcohol withdrawal. Pirenzepine An antimuscarinic agent used to treat peptic ulcers, gastric ulcers, and duodenal ulcers. Galantamine A cholinesterase inhibitor used to manage mild to moderate dementia associated with Alzheimer's Disease. Flurazepam A long-acting benzodiazepine with a rapid onset of action that is commonly used to treat insomnia. Fenoldopam A dopamine D1 receptor agonist used for the short term management of hypertension. Halazepam Used to relieve anxiety, nervousness, and tension associated with anxiety disorders. Diazepam A long-acting benzodiazepine with rapid onset commonly used to treat panic disorders, severe anxiety, alcohol withdrawal, and seizures. Oxazepam An intermediate-acting benzodiazepine with slow onset commonly used to treat panic disorders, severe anxiety, alcohol withdrawals, and insomnia. Triazolam A benzodiazepine used for short term treatment of insomnia. Clonazepam A long-acting benzodiazepine with intermediate onset commonly used to treat panic disorders, severe anxiety, and seizures. Flumazenil A benzodiazepine antagonist that is used for the complete or partial reversal of the sedative effects caused by benzodiazepines in various clinical settings, such as induced general anesthesia for diagnostic and therapeutic procedures. Estazolam A benzodiazepine used for the short-term management of insomnia. Varenicline A partial agonist at nicotinic acetylcholine receptors used as an aid in smoking cessation. Haloxazolam Not Available Camazepam Camazepam has been used in placebo controlled studies for the treatment of patients suffering from anxiety and depression. Delorazepam A benzodiazepine used to manage severe anxiety disorders and insomnia. Flunitrazepam A benzodiazepine used to manage anxiety disorders and insomnia. Ethyl loflazepate Not Available Cloxazolam Used primarily as an anti-anxiety agent. Typically used short term, and may be given as a single dose of up to 100mcg/kg to reduce anxiety and tension experienced prior to... Bromazepam A short-acting benzodiazepine with intermediate onset commonly used to treat panic disorders and severe anxiety. Fludiazepam Used for the short-term treatment of anxiety disorders. Ketazolam A long-acting benzodiazepine used to manage anxiety and insomnia. Prazepam A benzodiazepine used to manage more severe forms of anxiety disorders. Quazepam A long -acting benzodiazepine used to manage insomnia. Cinolazepam A benzodiazepine used to manage severe and debilitating forms of sleep disorders of various origins in adults. Nitrazepam A long-acting benzodiazepine with intermediate onset commonly used to treat panic disorders, severe anxiety, insomnia, and seizures. Omacetaxine mepesuccinate A cephalotaxine used in the treatment of Chronic Myeloid Leukemia (CML) that is intolerant to or resistant to two or more tyrosine kinase inhibitors. Talampanel For the treatment of epilepsy. EVT 201 Investigated for use/treatment in insomnia. Tarazepide Investigated for use/treatment in gastrointestinal diseases and disorders (miscellaneous). S-8510 Investigated for use/treatment in alzheimer's disease and dementia. Dextofisopam Investigated for use/treatment in irritable bowel syndrome (IBS). Tofisopam For the treatment of anxiety and alcohol withdrawal. Etizolam A thienodiazepine derivative used to treat anxiety and insomnia. Aptazapine Investigated for the treatment of depression. Evacetrapib Evacetrapib has been used in trials studying the basic science and treatment of Dyslipidemia, Hyperlipidemia, Hypercholesterolemia, Hepatic Insufficiency, and Cardiovascular Disease. SJG-136 SJG-136 has been used in trials studying the treatment of Recurrent Fallopian Tube Cancer, Secondary Acute Myeloid Leukemia, de Novo Myelodysplastic Syndromes, Recurrent Ovarian Epithelial Cancer, and Secondary Myelodysplastic Syndromes,... BMS-906024 BMS-906024 has been used in trials studying the treatment of Cancer, Lymphoblastic Leukemia, Acute T-cell, and Precursor T-Cell Lymphoblastic Lymphoma. GI-181771X Gski181771 X is under investigation in clinical trial NCT00600743 (Effect of a CCK-1R Agonist on Food Intake in Humans). Netazepide Netazepide has been used in trials studying the prevention and treatment of Dyspepsia, Hypergastrinaemia, Barrett's Esophagus, ECL-cell Hyperplasia, and Rebound Hyperacidity, among others. Remimazolam An ultra short-acting benzodiazepine used for the induction and maintenence of procedural sedation during short procedures. 1,2-Benzodiazepine Benzodiazepine is under investigation for the prevention of Delirium and C.Surgical Procedure; Cardiac. Benzodiazepine has been investigated for the treatment of Obesity, Sleep Apnea, Obstructive, and Disorders of Gallbladder, Biliary... Indiplon Indiplon has been used in trials studying the treatment of Insomnia and Depression. PF-477736 PF-00477736 has been used in trials studying the treatment of Neoplasms. CE-326597 CE-326,597 has been used in trials studying the treatment of Obesity. Tetrazepam Not Annotated Pinazepam Not Annotated Medazepam A long-acting benzodiazepine used for its sedative and anxiolytic properties. Loprazolam Loprazolam is an imidazobenzodiazepine with anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties. It is indicated for the short-term treatment of insomnia including difficulty in falling asleep and/or frequent... Doxefazepam Not Annotated Lormetazepam For the treatment of short-term insomnia Nordazepam An intermediate in the metabolism of DIAZEPAM to OXAZEPAM. It may have actions similar to those of diazepam. Oxazepam acetate Not Annotated Cinazepam Not Annotated BMS-214662 BMS-214662 has been used in trials studying the treatment of Childhood Myelodysplastic Syndromes, Refractory Anemia With Excess Blasts, Recurrent Adult Acute Myeloid Leukemia, Relapsing Chronic Myelogenous Leukemia, and Adult Acute... Iomazenil Iomazenil is under investigation in clinical trial NCT01590277 (Ability of Partial Inverse Agonist, Iomazenil, to Block Ethanol Effects in Humans). RSV-604 RSV-604 is under investigation in clinical trial NCT00416442 (Safety, Tolerability and Pharmacokinetic Study of Single and Multiple Intravenous Doses of RSV604 in Healthy Subjects.). Tolvaptan A selective vasopressin V2-receptor antagonist to slow kidney function decline in patients at risk for rapidly progressing autosomal dominant polycystic kidney disease (ADPKD). Also used to treat hypervolemic and euvolemic hyponatremia. Ivabradine A HCN channel blocker used to reduce the risk of hospitalization for worsening heart failure in adult patients and for treatment of stable symptomatic heart failure as a result of dilated cardiomyopathy in pediatric patients. Vadastuximab talirine Vadastuximab Talirine has been used in trials studying the treatment of Acute myeloid leukemia, Myelodysplastic Syndrome, Acute Myelogenous Leukemia, and Acute Promyelocytic Leukemia. Rovalpituzumab tesirine Rovalpituzumab Tesirine has been used in trials studying the treatment of GLIOBLASTOMA, Malignant Melanoma, Other Solid Tumors, Small Cell Lung Cancer, and Medullary Thyroid Cancer, among others. BMS-986115 BMS-986115 has been used in trials studying the treatment of Various Advanced Cancer. Pyrazolam Not Annotated Mexazolam A benzodiazepine indicated to treat anxiety with or without psychoneurotic conditions. Oxazolam Not Annotated R-82913 Not Available Ro 24-7429 Ro 24-7429 is under investigation in clinical trial NCT00002314 (A Study of Ro 24-7429 in Patients With Hiv-related Kaposi's Sarcoma). Molibresib Molibresib is under investigation in clinical trial NCT01943851 (A Dose Escalation Study to Investigate the Safety, Pharmacokinetics (PK), Pharmacodynamics (PD) and Clinical Activity of GSK525762 in Subjects With Relapsed, Refractory...
- Drugs & Drug Targets