Coughing

Also known as: Cough / Coughs / C/O - cough

DrugDrug NameDrug Description
DB01246AlimemazineAn antihistamine agent used to prevent and relieve allergic conditions which cause pruritus and other allergic skin conditions, including urticaria.
DB01435AntipyrineAn antipyretic agent used for the symptomatic treatment of acute otitis media, most commonly in combination with benzocaine.
DB00868BenzonatateA non-narcotic oral antitussive drug used to suppress coughing.
DB01114ChlorpheniramineA histamine-H1 receptor antagonist indicated for the management of symptoms associated with upper respiratory allergies.
DB14006Choline salicylateThe oral gel is indicated for the relief of pain and discomfort of common mouth ulcers, cold sores, denture sore spots, infant teething and mouth ulcers, and sore spots due...
DB04837ClofedanolAn antitussive used for the symptomatic relief of acute cough caused by minor throat and bronchial irritation.
DB09002CloperastineCloperastine is a cough suppressant that acts on the central nervous system.
DB00318CodeineAn opioid analgesic used to treat moderate to severe pain when the use of an opioid is indicated.
DB00514DextromethorphanAn NMDA receptor antagonist used to treat cases of dry cough.
DB00645DyclonineAn topical anesthetic used prior to examination to suppress the gag reflex or for pain relief from canker sores and fever blisters.
DB00725Homatropine methylbromideA muscarinic receptor antagonist used to treat peptic ulcers, gastric ulcers, and duodenal ulcers.
DB00956HydrocodoneAn opioid agonist used as an analgesic and antitussive agent.
DB12472LevodropropizineLevodropropizine is under investigation in clinical trial NCT01573663 (A Drug-Drug Interaction Study of Ambroxol and Levodropropizine).
DB00825LevomentholAn organic compound used to treat mild to moderate muscle and joint pain.
DB13216OxolamineOxolamine is not approved in the USA, it may be marketed elsewhere internationally as a cough suppressant . It is listed as a prescription drug in New Zealand legislation ....
DB11186PentoxyverineA medication used to suppress a cough in the common cold, flu, bronchitis, and sinusitis.
DB00397PhenylpropanolamineA sympathomimetic that was previously used in nasal decongestants and weight loss products, but has been withdrawn by the FDA due to safety risks and lack of efficacy.
DB09209PholcodinePholcodine is indicated as a cough suppressant for the temporary relief of non-productive dry cough. It is stated to present a required label indication of "temporary relief of dry cough."...
DB01069PromethazineA first-generation antihistamine used for the treatment of allergic conditions, nausea and vomiting, and motion sickness.
DB12248TulobuterolTulobuterol has been used in trials studying the treatment of Chronic Obstructive Pulmonary Disease.
DrugDrug NameTargetType
DB01246AlimemazineHistamine H1 receptortarget
DB01435AntipyrineCytochrome P450 2C8enzyme
DB01435AntipyrineCytochrome P450 2C9enzyme
DB01435AntipyrineCytochrome P450 1A2enzyme
DB01435AntipyrineCytochrome P450 2C19enzyme
DB01435AntipyrineCytochrome P450 3A4enzyme
DB01435AntipyrineSolute carrier family 22 member 6transporter
DB01435AntipyrineCytochrome P450 2A6enzyme
DB01435AntipyrineCytochrome P450 2B6enzyme
DB01435AntipyrineCytochrome P450 2C18enzyme
DB01435AntipyrineCytochrome P450 2D6enzyme
DB01435AntipyrineCytochrome P450 2E1enzyme
DB01435AntipyrineProstaglandin G/H synthase 2target
DB01435AntipyrineProstaglandin G/H synthase 1target
DB00868BenzonatateSodium channel protein type 5 subunit alphatarget
DB00868BenzonatateCholinesteraseenzyme
DB01114ChlorpheniramineHistamine H1 receptortarget
DB01114ChlorpheniramineCytochrome P450 3A4enzyme
DB01114ChlorpheniramineCytochrome P450 2D6enzyme
DB01114ChlorpheniramineSodium-dependent serotonin transportertarget
DB01114ChlorpheniramineSodium-dependent noradrenaline transportertarget
DB01114ChlorpheniramineSodium-dependent dopamine transportertarget
DB01114ChlorpheniramineCytochrome P450 3A5enzyme
DB01114ChlorpheniramineCytochrome P450 3A7enzyme
DB01114ChlorpheniramineSolute carrier family 22 member 2transporter
DB01114ChlorpheniramineSolute carrier family 22 member 1transporter
DB14006Choline salicylateCholine-phosphate cytidylyltransferase Btarget
DB14006Choline salicylateAcetylcholinesterasetarget
DB14006Choline salicylateCholine-phosphate cytidylyltransferase Atarget
DB14006Choline salicylatePhospholipase D2target
DB14006Choline salicylateCholinesterasetarget
DB14006Choline salicylatePhospholipase D1target
DB14006Choline salicylateSolute carrier family 22 member 2transporter
DB14006Choline salicylateSolute carrier family 22 member 1transporter
DB14006Choline salicylateSolute carrier family 22 member 3transporter
DB14006Choline salicylateSolute carrier family 22 member 5transporter
DB14006Choline salicylateSolute carrier family 22 member 4transporter
DB14006Choline salicylateCholine/ethanolaminephosphotransferase 1enzyme
DB14006Choline salicylateCholine transporter-like protein 1transporter
DB14006Choline salicylateCholine transporter-like protein 4transporter
DB14006Choline salicylateCholine transporter-like protein 3transporter
DB14006Choline salicylateCholine/ethanolamine kinaseenzyme
DB14006Choline salicylateCholine O-acetyltransferaseenzyme
DB14006Choline salicylateCholine kinase alphaenzyme
DB14006Choline salicylateCholine dehydrogenase, mitochondrialenzyme
DB14006Choline salicylateHigh affinity choline transporter 1transporter
DB14006Choline salicylateNeuronal acetylcholine receptor subunit alpha-7target
DB04837ClofedanolHistamine H1 receptortarget
DB00318CodeineMu-type opioid receptortarget
DB00318CodeineDelta-type opioid receptortarget
DB00318CodeineKappa-type opioid receptortarget
DB00318CodeineCytochrome P450 2D6enzyme
DB00318CodeineCytochrome P450 3A4enzyme
DB00318CodeineSolute carrier family 22 member 1transporter
DB00318CodeineUDP-glucuronosyltransferase 2B7enzyme
DB00318CodeineUDP-glucuronosyltransferase 2B4enzyme
DB00514DextromethorphanSigma non-opioid intracellular receptor 1target
DB00514DextromethorphanHCG20471, isoform CRA_ctarget
DB00514DextromethorphanNeuronal acetylcholine receptor subunit alpha-2target
DB00514DextromethorphanSodium-dependent serotonin transportertarget
DB00514DextromethorphanGlutamate receptor ionotropic, NMDA 3Atarget
DB00514DextromethorphanCytochrome P450 2D6enzyme
DB00514DextromethorphanCytochrome P450 3A4enzyme
DB00514DextromethorphanCytochrome P450 3A7enzyme
DB00514DextromethorphanCytochrome P450 2C9enzyme
DB00514DextromethorphanCytochrome P450 2B6enzyme
DB00514DextromethorphanCytochrome P450 2C19enzyme
DB00514DextromethorphanMembrane-associated progesterone receptor component 1target
DB00514DextromethorphanNeuronal acetylcholine receptor subunit alpha-3target
DB00514DextromethorphanNeuronal acetylcholine receptor subunit alpha-4target
DB00514DextromethorphanNeuronal acetylcholine receptor subunit beta-4target
DB00514DextromethorphanNeuronal acetylcholine receptor subunit beta-2target
DB00514DextromethorphanNeuronal acetylcholine receptor subunit alpha-7target
DB00514DextromethorphanMu-type opioid receptortarget
DB00514DextromethorphanDelta-type opioid receptortarget
DB00514DextromethorphanKappa-type opioid receptortarget
DB00514DextromethorphanNADPH oxidasetarget
DB00514DextromethorphanSodium-dependent noradrenaline transportertarget
DB00514DextromethorphanUDP-glucuronosyltransferase 2B4enzyme
DB00514DextromethorphanUDP-glucuronosyltransferase 2B7enzyme
DB00514DextromethorphanUDP-glucuronosyltransferase 2B15enzyme
DB00514DextromethorphanUDP-glucuronosyltransferase 2B17enzyme
DB00645DyclonineSodium channel protein type 10 subunit alphatarget
DB00725Homatropine methylbromideMuscarinic acetylcholine receptor M2target
DB00725Homatropine methylbromideMuscarinic acetylcholine receptor M1target
DB00725Homatropine methylbromideMuscarinic acetylcholine receptor M4target
DB00725Homatropine methylbromideMuscarinic acetylcholine receptor M5target
DB00725Homatropine methylbromideMuscarinic acetylcholine receptor M3target
DB00956HydrocodoneMu-type opioid receptortarget
DB00956HydrocodoneDelta-type opioid receptortarget
DB00956HydrocodoneCytochrome P450 3A4enzyme
DB00956HydrocodoneCytochrome P450 2D6enzyme
DB00956HydrocodoneCytochrome P450 2B6enzyme
DB00956HydrocodoneCytochrome P450 2C19enzyme
DB00956HydrocodoneSigma non-opioid intracellular receptor 1target
DB00825LevomentholTransient receptor potential cation channel subfamily A member 1target
DB00825LevomentholTransient receptor potential cation channel subfamily M member 8target
DB00825LevomentholTransient receptor potential cation channel subfamily V member 3target
DB00825LevomentholKappa-type opioid receptortarget
DB00825LevomentholVoltage-dependent L-type calcium channeltarget
DB00825LevomentholCytochrome P450 3A4enzyme
DB11186PentoxyverineSigma non-opioid intracellular receptor 1target
DB11186PentoxyverinePotassium voltage-gated channel subfamily H member 2target
DB11186PentoxyverineVoltage-gated sodium channel alpha subunittarget
DB11186PentoxyverineKappa-type opioid receptortarget
DB11186PentoxyverineMu-type opioid receptortarget
DB00397PhenylpropanolamineAmine oxidase [flavin-containing] Aenzyme
DB00397PhenylpropanolamineDopamine D1 receptortarget
DB00397PhenylpropanolamineBeta-1 adrenergic receptortarget
DB00397PhenylpropanolamineBeta-2 adrenergic receptortarget
DB00397PhenylpropanolamineAlpha-2 adrenergic receptorstarget
DB09209PholcodineMu-type opioid receptortarget
DB09209PholcodineKappa-type opioid receptortarget
DB09209PholcodineDelta-type opioid receptortarget
DB01069PromethazineDopamine D2 receptortarget
DB01069PromethazineHistamine H1 receptortarget
DB01069PromethazineMuscarinic acetylcholine receptor M4target
DB01069PromethazineMuscarinic acetylcholine receptor M1target
DB01069PromethazineMuscarinic acetylcholine receptor M5target
DB01069PromethazineMuscarinic acetylcholine receptor M2target
DB01069PromethazineMuscarinic acetylcholine receptor M3target
DB01069PromethazineCalmodulintarget
DB01069PromethazineCytochrome P450 2D6enzyme
DB01069PromethazineCytochrome P450 2B6enzyme
DB01069PromethazineP-glycoprotein 1transporter
DB01069PromethazineCytochrome P450 2C9enzyme
DB01069PromethazineHistamine H2 receptortarget
DB01069PromethazineAlpha adrenergic receptortarget
DB01069PromethazineP2 Purinoceptorstarget
DB01069PromethazineVoltage-gated sodium channel alpha subunittarget
DB01069PromethazineVoltage-gated Potassium Channelstarget
DB01069PromethazineCanalicular multispecific organic anion transporter 2transporter
DB01069PromethazineMultidrug resistance-associated protein 4transporter
DB01069PromethazineSerum albumincarrier
DB12248TulobuterolBeta-2 adrenergic receptortarget
DrugDrug NamePhaseStatusCount
DB00868Benzonatate1Completed1
DB00868Benzonatate1Recruiting1
DB06774Capsaicin1Recruiting1
DB00318Codeine1Completed2
DB00514Dextromethorphan1Completed1
DB00003Dornase alfa1Withdrawn1
DB00874Guaifenesin1Completed2
DB14242Honey1Completed1
DB00281Lidocaine1Completed1
DB00683Midazolam1Recruiting1
DB00218Moxifloxacin1Recruiting1
DB06774Capsaicin1 / 2Completed2
DB04465Lactose1 / 2Recruiting1
DB00683Midazolam1 / 2Completed1
DB00230Pregabalin1 / 2Recruiting1
DB06742Ambroxol2Completed1
DB06774Capsaicin2Recruiting1
DB11131Capsicum oleoresin2Recruiting1
DB15097Gefapixant2Completed1
DB12664Indantadol2Terminated1
DB00034Interferon alfa-2a, Recombinant2Terminated1
DB06282Levocetirizine2Completed1
DB00471Montelukast2Unknown Status1
DB00844Nalbuphine2Recruiting1
DB09291Rolapitant2Completed1
DB12782SCH-4867572Completed2
DB01001Salbutamol2Not Yet Recruiting1
DB09153Sodium chloride2Not Yet Recruiting1
DB14487Zinc acetate2Completed1
DB00207Azithromycin3Completed1
DB00868Benzonatate3Unknown Status1
DB00443Betamethasone3Completed1
DB00835Brompheniramine3Withdrawn1
DB00297Bupivacaine3Not Yet Recruiting1
DB01744Camphor3Unknown Status1
DB01075Diphenhydramine3Withdrawn1
DB13785Dropropizine3Withdrawn1
DB03852Eucalyptol3Unknown Status1
DB15097Gefapixant3Recruiting2
DB11359Guaiacol3Terminated1
DB11359Guaiacol3Unknown Status1
DB00874Guaifenesin3Completed1
DB00874Guaifenesin3Unknown Status1
DB12472Levodropropizine3Completed1
DB00825Levomenthol3Unknown Status1
DB00281Lidocaine3Completed1
DB00281Lidocaine3Recruiting1
DB00338Omeprazole3Terminated1
DB13820Oxomemazine3Completed1
DB06614Peramivir3Completed1
DB06614Peramivir3Terminated1
DB00388Phenylephrine3Withdrawn1
DB13397Prenoxdiazine3Completed1
DB00852Pseudoephedrine3Withdrawn1
DB00863Ranitidine3Terminated1
DB01041Thalidomide3Completed1
DB01412Theobromine3Completed1
DB00620Triamcinolone3Not Yet Recruiting1
DB04339Carbocisteine4Completed1
DB00633Dexmedetomidine4Completed1
DB00514Dextromethorphan4Terminated1
DB00736Esomeprazole4Completed1
DB00813Fentanyl4Completed1
DB06709Methacholine4Not Yet Recruiting1
DB00471Montelukast4Completed3
DB00471Montelukast4Unknown Status1
DB00860Prednisolone4Completed1
DB00899Remifentanil4Completed3
DB00899Remifentanil4Not Yet Recruiting1
DB10319Streptococcus pneumoniae type 1 capsular polysaccharide antigen4Completed1
DB10332Streptococcus pneumoniae type 14 capsular polysaccharide antigen4Completed1
DB10335Streptococcus pneumoniae type 18c capsular polysaccharide antigen4Completed1
DB10336Streptococcus pneumoniae type 19f capsular polysaccharide antigen4Completed1
DB10340Streptococcus pneumoniae type 23f capsular polysaccharide antigen4Completed1
DB10322Streptococcus pneumoniae type 4 capsular polysaccharide antigen4Completed1
DB10323Streptococcus pneumoniae type 5 capsular polysaccharide antigen4Completed1
DB10324Streptococcus pneumoniae type 6b capsular polysaccharide antigen4Completed1
DB10325Streptococcus pneumoniae type 7f capsular polysaccharide antigen4Completed1
DB10328Streptococcus pneumoniae type 9v capsular polysaccharide antigen4Completed1
DB00171ATPNot AvailableRecruiting1
DB00207AzithromycinNot AvailableCompleted1
DB06774CapsaicinNot AvailableCompleted1
DB06774CapsaicinNot AvailableRecruiting1
DB04272Citric acidNot AvailableCompleted1
DB00633DexmedetomidineNot AvailableCompleted1
DB05381HistamineNot AvailableCompleted1
DB01592IronNot AvailableCompleted1
DB00281LidocaineNot AvailableCompleted3
DB00281LidocaineNot AvailableNot Yet Recruiting1
DB00455LoratadineNot AvailableCompleted1
DB00471MontelukastNot AvailableCompleted1
DB00471MontelukastNot AvailableUnknown Status1
DB00338OmeprazoleNot AvailableCompleted1
DB01366ProcaterolNot AvailableUnknown Status1
DB00818PropofolNot AvailableCompleted1
DB00899RemifentanilNot AvailableCompleted4
DB00899RemifentanilNot AvailableNot Yet Recruiting1
DB01001SalbutamolNot AvailableCompleted1