Lung Transplant Rejection

Also known as: Lung transplant rejection

Drug	Drug Name	Drug Description
DB09312	Antilymphocyte immunoglobulin (horse)	A primarily IgG immune globulin used to manage allograft rejection in renal transplant patients.
DB00877	Sirolimus	An immunosuppressant used to prevent organ transplant rejections and to treat lymphangioleiomyomatosis.

Drug	Drug Name	Target	Type
DB00877	Sirolimus	Peptidyl-prolyl cis-trans isomerase FKBP1A	target
DB00877	Sirolimus	Cytochrome P450 3A4	enzyme
DB00877	Sirolimus	Serine/threonine-protein kinase mTOR	target
DB00877	Sirolimus	Fibroblast growth factor 2	target
DB00877	Sirolimus	Cytochrome P450 3A5	enzyme
DB00877	Sirolimus	Cytochrome P450 3A7	enzyme
DB00877	Sirolimus	P-glycoprotein 1	transporter
DB00877	Sirolimus	Solute carrier organic anion transporter family member 1B1	transporter
DB00877	Sirolimus	Multidrug and toxin extrusion protein 1	transporter

Drug	Drug Name	Phase	Status	Count
DB00098	Antithymocyte immunoglobulin (rabbit)	2	Recruiting	1
DB06681	Belatacept	2	Recruiting	1
DB06681	Belatacept	2	Withdrawn	1
DB08889	Carfilzomib	2	Recruiting	1
DB08889	Carfilzomib	2	Withdrawn	1
DB00959	Methylprednisolone	2	Recruiting	1
DB00688	Mycophenolate mofetil	2	Recruiting	1
DB01024	Mycophenolic acid	2	Recruiting	1
DB04951	Pirfenidone	2	Active Not Recruiting	1
DB00635	Prednisone	2	Recruiting	1
DB00864	Tacrolimus	2	Recruiting	1
DB00091	Cyclosporine	3	Recruiting	2
DB08932	Macitentan	4	Withdrawn	1