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Displaying targets 4176 - 4200 of 6103 in total
TargetOrganismDescription# of Drugs
Phosphatidylinositol 3-kinase catalytic subunit type 3HumansCatalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex ...  more2Details
Phosphatidylinositol 3-kinase regulatory subunit alphaHumansBinds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating th...  more3Details
Phosphatidylinositol 3-kinase regulatory subunit betaHumansRegulatory subunit of phosphoinositide-3-kinase (PI3K), a kinase that phosphorylates PtdIns(4,5)P2 (Phosphatidylinosi...  more1Details
Phosphatidylinositol 3-kinase regulatory subunit gammaHumansBinds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activi...  more1Details
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformHumansPhosphoinositide-3-kinase (PI3K) phosphorylates phosphatidylinositol (PI) and its phosphorylated derivatives at posit...  more19Details
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformHumansPhosphoinositide-3-kinase (PI3K) phosphorylates phosphatidylinositol derivatives at position 3 of the inositol ring t...  more12Details
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformHumansPhosphoinositide-3-kinase (PI3K) phosphorylates phosphatidylinositol (PI) and its phosphorylated derivatives at posit...  more29Details
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoformHumansPhosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generat...  more47Details
Phosphatidylinositol 4-kinase betaHumansPhosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inosit...  more4Details
Phosphatidylinositol 4-kinase type 2-betaHumansTogether with PI4K2A and the type III PI4Ks (PIK4CA and PIK4CB) it contributes to the overall PI4-kinase activity of ...  more1Details
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit betaHumansPhosphorylates PtdIns and PtdIns4P with a preference for PtdIns. Does not phosphorylate PtdIns(4,5)P2. May be involve...  more1Details
Phosphatidylinositol 5-phosphate 4-kinase type-2 betaHumansParticipates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. Preferentially utilizes GTP, rather than A...  more1Details
Phosphatidylinositol 5-phosphate 4-kinase type-2 gammaHumansPhosphatidylinositol 5-phosphate 4-kinase with low enzymatic activity. May be a GTP sensor, has higher GTP-dependent ...  more1Details
Phosphatidylinositol transfer protein alpha isoformHumansCatalyzes the transfer of phosphatidylinositol (PI) and phosphatidylcholine (PC) between membranes. Shows a preferenc...  more2Details
Phosphatidylserine decarboxylase proenzyme, mitochondrialHumansCatalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role i...  more1Details
Phosphatidylserine synthase 1HumansCatalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylchol...  more1Details
Phosphatidylserine synthase 2HumansCatalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-se...  more1Details
Phospho-2-dehydro-3-deoxyheptonate aldolaseThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)Catalyzes the condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-ar...  more2Details
Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitiveEscherichia coli (strain K12)Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-a...  more2Details
Phosphocarrier protein HPrEnterococcus faecalis (strain ATCC 700802 / V583)General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PT...  more1Details
Phosphocarrier protein HPrBacillus subtilis (strain 168)General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PT...  more1Details
PhosphodiesteraseHumansNot Available1Details
PhosphodiesteraseTrypanosoma cruziNot Available1Details
Phosphodiesterase 3HumansNot Available19Details
Phosphodiesterase 4HumansNot Available32Details
Displaying targets 4176 - 4200 of 6103 in total