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Displaying targets 1526 - 1550 of 6103 in total
TargetOrganismDescription# of Drugs
Cytochrome P450 2B1RatCytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADP...  more12Details
Cytochrome P450 2B6HumansA cytochrome P450 monooxygenase involved in the metabolism of endocannabinoids and steroids. Mechanistically, uses mo...  more255Details
Cytochrome P450 2C11RatA cytochrome P450 monooxygenase involved in the metabolism of steroid hormones and fatty acids. Catalyzes the hydroxy...  more4Details
Cytochrome P450 2C12, female-specificRatThis P450 is active in 15-beta-hydroxylation of steroid sulfates.1Details
Cytochrome P450 2C18HumansA cytochrome P450 monooxygenase involved in retinoid metabolism. Hydroxylates all trans-retinoic acid (atRA) to 4-hyd...  more31Details
Cytochrome P450 2C19HumansA cytochrome P450 monooxygenase involved in the metabolism of polyunsaturated fatty acids (PUFA). Mechanistically, us...  more383Details
Cytochrome P450 2C6RatCytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADP...  more2Details
Cytochrome P450 2C8HumansA cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, s...  more354Details
Cytochrome P450 2C9HumansA cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids an...  more471Details
Cytochrome P450 2D6HumansA cytochrome P450 monooxygenase involved in the metabolism of fatty acids, steroids and retinoids. Mechanistically, u...  more481Details
Cytochrome P450 2E1HumansA cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen ins...  more168Details
Cytochrome P450 2F1HumansMay be involved in the metabolism of various pneumotoxicants including naphthalene. Is able to dealkylate ethoxycouma...  more1Details
Cytochrome P450 2J2HumansA cytochrome P450 monooxygenase involved in the metabolism of polyunsaturated fatty acids (PUFA) in the cardiovascula...  more28Details
Cytochrome P450 3A SubfamilyHumansNot Available84Details
Cytochrome P450 3A1RatCytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADP...  more5Details
Cytochrome P450 3A2RatCytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADP...  more5Details
Cytochrome P450 3A4HumansA cytochrome P450 monooxygenase involved in the metabolism of sterols, steroid hormones, retinoids and fatty acids. M...  more1,178Details
Cytochrome P450 3A43HumansExhibits low testosterone 6-beta-hydroxylase activity in vitro. The physiological substrate of this enzyme is unknown15Details
Cytochrome P450 3A5HumansA cytochrome P450 monooxygenase involved in the metabolism of steroid hormones and vitamins. Mechanistically, uses mo...  more324Details
Cytochrome P450 3A7HumansA cytochrome P450 monooxygenase involved in the metabolism of steroid hormones and vitamins during embryogenesis. Mec...  more140Details
Cytochrome P450 4A11HumansA cytochrome P450 monooxygenase involved in the metabolism of fatty acids and their oxygenated derivatives (oxylipins...  more14Details
Cytochrome P450 4B1HumansCatalyzes the omega- and (omega-1)-hydroxylation of saturated fatty acids and n-alkanes. Also bioactivates xenobiotic...  more2Details
Cytochrome P450 4F12HumansA cytochrome P450 monooxygenase involved in the metabolism of endogenous polyunsaturated fatty acids (PUFAs). Mechani...  more2Details
Cytochrome P450 4F2HumansA cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, e...  more12Details
Cytochrome P450 4F3HumansA cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids an...  more2Details
Displaying targets 1526 - 1550 of 6103 in total