Targets

Advanced Filter

Filter by Group

Filter by Market Availability

Displaying targets 1626 - 1650 of 6103 in total
TargetOrganismDescription# of Drugs
Deoxyguanosine kinase, mitochondrialHumansPhosphorylates deoxyguanosine and deoxyadenosine in the mitochondrial matrix, with the highest efficiency for deoxygu...  more3Details
Deoxyhypusine hydroxylaseHumansCatalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate produced by deoxyhypusine synthase/DHPS ...  more1Details
Deoxyhypusine synthaseHumansCatalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of ...  more2Details
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1HumansProtein that acts both as a host restriction factor involved in defense response to virus and as a regulator of DNA e...  more1Details
Deoxynucleotide monophosphate kinaseEnterobacteria phage T4Phosphorylates dGMP, dTMP and 5-hydroxymethyl-dCMP while excluding dCMP and dAMP. The phosphorylation of 5-hydroxymet...  more2Details
Deoxyribodipyrimidine photo-lyaseEscherichia coli (strain K12)Involved in repair of UV radiation-induced DNA damage. Catalyzes the light-dependent monomerization (300-600 nm) of c...  more1Details
Deoxyribodipyrimidine photo-lyaseThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)Involved in repair of UV radiation-induced DNA damage. Catalyzes the light-dependent monomerization (300-600 nm) of c...  more2Details
Deoxyribodipyrimidine photo-lyaseSynechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1)Involved in repair of UV radiation-induced DNA damage. Catalyzes the light-dependent monomerization (300-600 nm) of c...  more1Details
Deoxyribonuclease-1HumansSerum endocuclease secreted into body fluids by a wide variety of exocrine and endocrine organs. Expressed by non-hem...  more3Details
Deoxyribonuclease-2-alphaHumansHydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the clearance...  more1Details
Deoxyribose-phosphate aldolaseEscherichia coli (strain K12)Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-rib...  more1Details
Deoxyribose-phosphate aldolaseThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-rib...  more1Details
Deoxyuridine 5'-triphosphate nucleotidohydrolasePlasmodium falciparum (isolate 3D7)Involved in nucleotide metabolism via production of dUMP, the immediate precursor of thymidine nucleotides, and decre...  more1Details
Deoxyuridine 5'-triphosphate nucleotidohydrolaseMycobacterium tuberculosisThis enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides ...  more4Details
Deoxyuridine 5'-triphosphate nucleotidohydrolaseEscherichia coli (strain K12)This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides ...  more4Details
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrialHumansCatalyzes the cleavage of 2'-deoxyuridine 5'-triphosphate (dUTP) into 2'-deoxyuridine 5'-monophosphate (dUMP) and ino...  more2Details
Deoxyuridine triphosphataseTrypanosoma cruziNot Available1Details
Dephospho-CoA kinaseEscherichia coli (strain K12)Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.1Details
Dermatan sulfateHumansNot Available2Details
DermcidinHumansFound in sweat, has an antimicrobial activity during early bacterial colonization. The secreted peptide assembles int...  more4Details
DesmoplakinHumansA component of desmosome cell-cell junctions which are required for positive regulation of cellular adhesion. Critica...  more3Details
DestrinHumansActin-depolymerizing protein. Severs actin filaments (F-actin) and binds to actin monomers (G-actin). Acts in a pH-in...  more1Details
Dethiobiotin synthetase BioDMycobacterium tuberculosisCatalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms...  more1Details
Devancosaminyl-vancomycin vancosaminetransferaseAmycolatopsis orientalisCatalyzes the attachment of L-vancosamine to a monoglucosylated heptapeptide intermediate during the final stage of g...  more1Details
Diablo IAP-binding mitochondrial proteinHumansPromotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. Acts by opposing the inhibito...  more1Details
Displaying targets 1626 - 1650 of 6103 in total