| Dihydrofolate reductase | Bacillus anthracis | Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DN... more | 1 | Details |
| Dihydrofolate reductase | Gallus gallus | Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes... more | 1 | Details |
| Dihydrofolate reductase | Humans | Catalyzes the reduction of 7,8-dihydrofolate (DHF) to 5,6,7,8-tetrahydrofolate in a NADPH-dependent manner. Key enzym... more | 39 | Details |
| Dihydrofolate reductase | Escherichia coli (strain K12) | Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DN... more | 9 | Details |
| Dihydrofolate reductase | Staphylococcus aureus (strain bovine RF122 / ET3-1) | Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DN... more | 5 | Details |
| Dihydrofolate reductase 2, mitochondrial | Humans | Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required ... more | 9 | Details |
| Dihydrofolate synthase/folylpolyglutamate synthase | Escherichia coli (strain K12) | Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate... more | 2 | Details |
| Dihydrolipoyl dehydrogenase | Neisseria meningitidis | Not Available | 1 | Details |
| Dihydrolipoyl dehydrogenase | Pseudomonas putida | The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA ... more | 1 | Details |
| Dihydrolipoyl dehydrogenase | Azotobacter vinelandii | The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains ... more | 1 | Details |
| Dihydrolipoyl dehydrogenase | Pseudomonas fluorescens | The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA ... more | 1 | Details |
| Dihydrolipoyl dehydrogenase, mitochondrial | Humans | Lipoamide dehydrogenase is a component of the glycine cleavage system as well as an E3 component of three alpha-ketoa... more | 5 | Details |
| Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex | Azotobacter vinelandii | The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains ... more | 3 | Details |
| Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial | Humans | The pyruvate dehydrogenase (PDH) complex, catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and t... more | 3 | Details |
| Dihydroneopterin aldolase | Staphylococcus aureus | Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin. Can also catalyze the epimeriz... more | 10 | Details |
| Dihydroorotase | Escherichia coli (strain K12) | Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. | 4 | Details |
| Dihydroorotate dehydrogenase (quinone) | Escherichia coli (strain K12) | Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. | 3 | Details |
| Dihydroorotate dehydrogenase (quinone), mitochondrial | Plasmodium falciparum (isolate 3D7) | Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. | 16 | Details |
| Dihydroorotate dehydrogenase (quinone), mitochondrial | Humans | Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. Required for UMP biosynthesi... more | 34 | Details |
| Dihydroorotate dehydrogenase A (fumarate) | Lactococcus lactis subsp. cremoris | Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor. | 2 | Details |
| Dihydrophenazinedicarboxylate synthase | Pseudomonas fluorescens | Involved in the biosynthesis of the antibiotic phenazine, a nitrogen-containing heterocyclic molecule having importan... more | 1 | Details |
| Dihydropteridine reductase | Humans | Catalyzes the conversion of quinonoid dihydrobiopterin into tetrahydrobiopterin | 2 | Details |
| Dihydropteroate synthase | Escherichia coli (strain K12) | Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) ... more | 35 | Details |
| Dihydropteroate synthase | Mycobacterium tuberculosis | Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) ... more | 1 | Details |
| Dihydropteroate synthase | Mycobacterium leprae (strain TN) | Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) ... more | 2 | Details |