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Displaying targets 2051 - 2075 of 6103 in total
TargetOrganismDescription# of Drugs
Eukaryotic translation initiation factor 2-alpha kinase 1HumansMetabolic-stress sensing protein kinase that phosphorylates the alpha subunit of eukaryotic translation initiation fa...  more1Details
Eukaryotic translation initiation factor 3 subunit CPlasmodium falciparum (isolate 3D7)Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis o...  more1Details
Eukaryotic translation initiation factor 3 subunit FHumansComponent of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in t...  more1Details
Eukaryotic translation initiation factor 4BHumansRequired for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the ...  more1Details
Eukaryotic translation initiation factor 4EHumansActs in the cytoplasm to initiate and regulate protein synthesis and is required in the nucleus for export of a subse...  more5Details
Eukaryotic translation initiation factor 6HumansBinds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initia...  more1Details
Evolved beta-galactosidase subunit alphaEscherichia coli (strain K12)The wild-type enzyme is an ineffective lactase. Two classes of point mutations dramatically improve activity of the e...  more1Details
Excitatory amino acid transporter 1HumansSodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate a...  more4Details
Excitatory amino acid transporter 2HumansSodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate a...  more4Details
Excitatory amino acid transporter 3HumansSodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate a...  more4Details
Excitatory amino acid transporter 4HumansSodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate a...  more1Details
Excitatory amino acid transporter 5HumansSodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate a...  more1Details
Excretory Secretory (ES) proteinsFasciola hepaticaThis protein group describes the proteins found in parasites which are crucial for survival, and represent possible t...  more1Details
Exoglucanase/xylanaseCellulomonas fimiHydrolyzes both cellulose and xylan. Has also weak endoglucanase activity.6Details
ExopolyphosphataseAquifex aeolicus (strain VF5)Not Available1Details
Exostosin-like 2HumansGlycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of ...  more3Details
Exotoxin APseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)An NAD-dependent ADP-ribosyltransferase (ADPRT). Catalyzes the transfer of the ADP ribosyl moiety of oxidized NAD (NA...  more2Details
Exportin-1HumansMediates the nuclear export of cellular proteins (cargos) bearing a leucine-rich nuclear export signal (NES) and of R...  more6Details
Extended-spectrum beta-lactamase PER-1Pseudomonas aeruginosaNot Available2Details
Extracellular calcium-sensing receptorHumansG protein-coupled receptor that senses changes in the extracellular concentration of calcium ions and plays a key rol...  more18Details
Extracellular signal-regulated kinase (ERK)HumansNot Available7Details
Extracellular sulfatase Sulf-2HumansExhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from ...  more2Details
F-box only protein 41HumansSubstrate-recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex. Required in t...  more1Details
F-box-like/WD repeat-containing protein TBL1XHumansF-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated ...  more1Details
F-box/WD repeat-containing protein 1AHumansSubstrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates...  more1Details
Displaying targets 2051 - 2075 of 6103 in total