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Displaying all 24 targets
Microtubule-associated protein tau
Matched Polypeptides specific function: … Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the …
Serine/arginine-rich splicing factor 4
Matched Polypeptides general function: … Represses the splicing of MAPT/Tau exon 10. …
Serine/threonine-protein kinase MARK1
Matched Polypeptides general function: … Phosphorylates DCX, MAP2, MAP4 and MAPT/TAU. ... Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/ …
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform
Matched Polypeptides general function: … In vitro, phosphorylates PYGM, TNNI3, MAPT/TAU, GAP43 and NRGN/RC3 (By similarity). …
Serine/threonine-protein phosphatase 5
Matched Polypeptides specific function: … Dephosphorylates and may play a role in the regulation of TAU/MAPT. ... ASK1/MAP3K5, PRKDC and RAF1, the nuclear receptors NR3C1, PPARG, ESR1 and ESR2, SMAD proteins and TAU/MAPT …
Dual specificity protein kinase CLK4
Matched Polypeptides general function: … Required for the regulation of alternative splicing of MAPT/TAU. …
Glycogen synthase kinase-3 beta
Matched Polypeptides specific function: … Phosphorylates MAPT/TAU on 'Thr-548', decreasing significantly MAPT/TAU ability to bind and stabilize ... MAPT/TAU is the principal component of neurofibrillary tangles in Alzheimer disease. ... glycogen synthase (GYS1 or GYS2), EIF2B, CTNNB1/beta-catenin, APC, AXIN1, DPYSL2/CRMP2, JUN, NFATC1/NFATC, MAPT …
Serine/threonine-protein kinase MARK2
Matched Polypeptides general function: … Phosphorylates CRTC2/TORC2, DCX, HDAC7, KIF13B, MAP2, MAP4, MAPT/TAU, and RAB11FIP2. ... Plays a key role in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT …
Mitogen-activated protein kinase 13
Matched Polypeptides specific function: … Involved in cytoskeletal remodeling through phosphorylation of MAPT and STMN1. …
Serine/threonine-protein kinase TAO1
Matched Polypeptides general function: … of MARK2, leading to activate MARK2 kinase activity and subsequent phosphorylation and detachment of MAPT …
MAP/microtubule affinity-regulating kinase 4
Matched Polypeptides general function: … Phosphorylates the microtubule-associated protein MAPT (PubMed:14594945, PubMed:23666762). …
Tyrosine-protein kinase Fyn
Matched Polypeptides specific function: … several proteins including the actin regulator WAS and the microtubule-associated proteins MAP2 and MAPT …
Cyclin-dependent kinase 5
Matched Polypeptides specific function: … SH3GLB1, PXN, PAK1, MCAM/MUC18, SEPT5, SYN1, DNM1, AMPH, SYNJ1, CDK16, RAC1, RHOA, CDC42, TONEBP/NFAT5, MAPT ... MAPT/TAU, MAP2, MAP1B), and modulates actin dynamics to regulate neurite growth and/or spine morphogenesis …
Serine/threonine-protein kinase N1
Matched Polypeptides general function: … Phosphorylates 'Ser-575', 'Ser-637' and 'Ser-669' of MAPT/Tau, lowering its ability to bind to microtubules …
Tyrosine-protein kinase Lck
Matched Polypeptides specific function: … Phosphorylates other substrates including RUNX3, PTK2B/PYK2, the microtubule-associated protein MAPT, …
Mitogen-activated protein kinase 3
Matched Polypeptides specific function: … as ATF2, BCL6, ELK1, ERF, FOS, HSF4 or SPZ1), cytoskeletal elements (such as CANX, CTTN, GJA1, MAP2, MAPT …
Extracellular signal-regulated kinase (ERK)
Matched Polypeptides specific function: … as ATF2, BCL6, ELK1, ERF, FOS, HSF4 or SPZ1), cytoskeletal elements (such as CANX, CTTN, GJA1, MAP2, MAPT ... as ATF2, BCL6, ELK1, ERF, FOS, HSF4 or SPZ1), cytoskeletal elements (such as CANX, CTTN, GJA1, MAP2, MAPT …
5'-AMP-activated protein kinase catalytic subunit alpha-1
Matched Polypeptides specific function: … response to amyloid beta A4 protein (APP) exposure, activated by CAMKK2, leading to phosphorylation of MAPT …
Mitogen-activated protein kinase 1
Matched Polypeptides specific function: … as ATF2, BCL6, ELK1, ERF, FOS, HSF4 or SPZ1), cytoskeletal elements (such as CANX, CTTN, GJA1, MAP2, MAPT …
Serine/threonine-protein kinase Sgk1
Matched Polypeptides specific function: … Phosphorylates MAPT/TAU and mediates microtubule depolymerization and neurite formation in hippocampal …
Tyrosine-protein kinase ABL1
Matched Polypeptides specific function: … ANXA1 (involved in membrane anchoring); DBN1, DBNL, CTTN, RAPH1 and ENAH (involved in signaling); or MAPT …
Cyclin-dependent kinase 1
Matched Polypeptides specific function: … RAP1GAP, RCC1, RPS6KB1/S6K1, KHDRBS1/SAM68, ESPL1, SKI, BIRC5/survivin, STIP1, TEX14, beta-tubulins, MAPT …
Mitogen-activated Protein Kinases
Matched Polypeptides specific function: … Involved in cytoskeletal remodeling through phosphorylation of MAPT and STMN1. ... as ATF2, BCL6, ELK1, ERF, FOS, HSF4 or SPZ1), cytoskeletal elements (such as CANX, CTTN, GJA1, MAP2, MAPT ... as ATF2, BCL6, ELK1, ERF, FOS, HSF4 or SPZ1), cytoskeletal elements (such as CANX, CTTN, GJA1, MAP2, MAPT …
5'-AMP-activated protein kinase
Matched Polypeptides specific function: … response to amyloid beta A4 protein (APP) exposure, activated by CAMKK2, leading to phosphorylation of MAPT …
Displaying all 24 targets