Isonicotinic Acids

Isonicotinic Acids
Accession Number

Heterocyclic acids that are derivatives of 4-pyridinecarboxylic acid (isonicotinic acid).

DrugDrug Description
EthionamideA second line antitubercular agent used to treat tuberculosis when other treatments have failed.
IsoniazidAn antibiotic used to treat mycobacterial infections; most commonly use in combination with other antimycobacterial agents for the treatment of active or latent tuberculosis.
IproniazidFor the treatment of depression (originally intended to treat tuberculosis).
NialamideWithdrawn from the Canadian, US, and UK markets in 1963 due to interactions with food products containing tyrosine.
ProtionamideAn antitubercular thioamide-derivative used in the treatment of multi-drug resistant (MDR) tuberculosis and leprosy.
AconiazideNot Annotated
Drugs & Drug Targets
EthionamideEnoyl-[acyl-carrier-protein] reductase [NADH]target
IsoniazidEnoyl-[acyl-carrier-protein] reductase [NADH]target
IsoniazidCytochrome P450 2E1enzyme
IsoniazidCytochrome P450 1A2enzyme
IsoniazidCytochrome P450 2C9enzyme
IsoniazidCytochrome P450 2D6enzyme
IsoniazidCytochrome P450 2C19enzyme
IsoniazidArylamine N-acetyltransferase 2enzyme
IsoniazidArylamine N-acetyltransferaseenzyme
IsoniazidCytochrome P450 2A6enzyme
IsoniazidCytochrome P450 2C8enzyme
IsoniazidCytochrome P450 2C8target
IsoniazidCytochrome P450 1A2target
IsoniazidCytochrome P450 3A4target
IsoniazidCytochrome P450 2C19target
IsoniazidDihydrofolate reductasetarget
IsoniazidSerum albumincarrier
IsoniazidCytochrome P450 3A4enzyme
IproniazidAmine oxidase [flavin-containing] Benzyme
IproniazidCytochrome P450 2D6enzyme
IproniazidCytochrome P450 2C9enzyme
IproniazidAmine oxidase [flavin-containing] Aenzyme
NialamideAmine oxidase [flavin-containing] Btarget
NialamideAmine oxidase [flavin-containing] Atarget
NialamideCatechol O-methyltransferasetarget