End-Stage Kidney Disease (ESKD) (DBCOND0156090)

Identifiers

Synonyms
End Stage Kidney Disease / Endstage Kidney Disease / End-Stage Kidney Disease / Chronic kidney disease, unspecified / End stage renal disease / Chronic kidney disease (CKD) / Chronic renal failure syndrome (disorder) / Renal failure chronic / Chronic renal failure / Kidney failure chronic / Kidney Failure, Chronic / End stage renal failure / End stage renal disease (ESRD) / End-stage renal disease (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Finerenone
A nonsteroidal mineralocorticoid receptor antagonist indicated to lower the risk of eGFR decline, end stage kidney disease, cardiovascular death, heart attack, and hospitalization for heart failure in chronic kidney disease associated with type 2 diabetes.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT05485961
Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysissupportive_care2 / 3recruiting
NCT03829488
Better Evidence for Selecting Transplant Fluidstreatment3completed
NCT05311956
Pain Reduction Using NEurostimulation StudyNo drug interventionstreatmentNot Availablerecruiting
NCT05430438
Effect of Low Versus Standard Dialysate Sodium on 48h Ambulatory BP in Patients With Intradialytic HypertensionNo drug interventionstreatmentNot Availablecompleted
NCT05558267
Potassium Containing Salt-Substitute in Hemodialysis-Dependent End Stage Kidney DiseaseNo drug interventionspreventionNot Availablenot_yet_recruiting
NCT04815850
Phenotyping Seroconversion Following Vaccination Against COVID-19 in Patients on Haemodialysis StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT06356168
Virtual Reality in End Stage Kidney DiseaseNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT06613568
Moda-flx Hemodialysis System™ Under Professional Care Settings by Trained Individuals and At Home by ParticipantsNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT05642364
Virtual Reality in Hemodialysis to Improve Psychological Well-beingNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT04669184
Sarcopenia and Physical Performance in Hemodialysis PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT02475551
Study to Evaluate the Safety, Tolerability, Efficacy and PK of IdeS in Kidney Transplantationtreatment2completed
NCT01530945
Mapping Multidimensional Illness Trajectories of Patients With End-stage Kidney DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT00798993
Effect of 25-hydroxyvitamin D and a Structured Exercise Program on Dialysis Patientstreatment4completed
NCT04160507
Duke APOL1 Research BiorepositoryNo drug interventionsNot AvailableNot Availablerecruiting
NCT05642156
Hemodynamics in Chronic Hemodialysis Patients Undergoing Isolated Ultrafiltration Compared to Conventional HemodialysisNo drug interventionstreatmentNot Availablerecruiting
NCT05425056
A Study Testing the Use of a Perivascular Sirolimus Formulation (Sirogen) in ESRD Patients Undergoing AV Fistula Surgeryprevention3active_not_recruiting
NCT04774770
HED-Start: Evaluating a Positive Skills Intervention for Patients New on HaemodialysisNo drug interventionssupportive_careNot Availablerecruiting
NCT03586518
Validating Novel, Non-contrast Cardiac MRI Imaging in Haemodialysis PatientsNo drug interventionsNot AvailableNot Availablerecruiting
NCT05418816
SelfWrap-Assisted Arteriovenous FistulasNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT02939586
The Effect of Haemodialysis in Sleep ApnoeaNo drug interventionstreatmentNot Availablecompleted
NCT00417339
Protein-bound Uremic Retention Solutes and Long Nocturnal Hemodialysis: a Longitudinal AnalysisNo drug interventionsNot AvailableNot Availablecompleted
NCT05836220
Parathyroid Hormone (PTH) Attenuation Trial in Hemodialysis-2No drug interventionstreatment3active_not_recruiting
NCT04626427
The WavelinQ™ Arterio-Venous Endovascular Fistula: A Global, Post-Market InvestigationNo drug interventionstreatmentNot Availableterminated
NCT04098627
The Effects of Laughter Therapy on Hemodialysis on DepressionNo drug interventionshealth_services_researchNot Availablecompleted
NCT05774392
An Observational Study of Patients With Chronic Kidney DiseaseNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT02363972
Percutaneous Less Invasive AV Fistula for Vascular Access in ESRDNo drug interventionstreatmentNot Availablecompleted
NCT04017572
Optimized vs. Standard Automated Peritoneal Dialysis Regimens StudyNo drug interventionstreatmentNot Availablecompleted
NCT03626246
Pathogenesis of Compromised Bone Quality and Mechanics in Chronic Kidney DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT05715814
meChANisms and sAfety of SGLT2 Inhibition in peRitoneal dialYsistreatment3not_yet_recruiting
NCT01977508
The Vascutek Rapidax™ II Post Market Surveillance RegistryNo drug interventionsNot AvailableNot Availableterminated
NCT02513303
Trial to Evaluate the Sirolimus-Eluting Collagen Implant on AV Fistula Outcomesprevention3completed
NCT00792454
Reduction of Mortality Prior to and During the First 90 Days of Dialysis Through a Renal Rehabilitation ProgramNo drug interventionspreventionNot Availablecompleted
NCT00649298
A Clinical Trial of IntensiVE DialysisNo drug interventionstreatment4completed
NCT06581393
First Evaluation of the Moda-Flx Hemodialysis System™ in Real World Clinical SettingsNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT05241171
The "Step4Life" Randomized Control Trial in HemodialysisNo drug interventionsotherNot Availablecompleted
NCT01859871
Evaluation of a Website on Living Kidney Donation for HispanicsNo drug interventionshealth_services_researchNot Availablecompleted
NCT05525507
Retro-active Immunological Tolerance in Patients With Well-functioning Pre-existing HLA-identical Kidney TransplantsNo drug interventionstreatment1recruiting
NCT04319185
Assisted Peritoneal Dialysis: A Feasibility StudyNo drug interventionsotherNot Availableunknown_status
NCT05806749
Immunological Tolerance in Patients With Mismatched Kidney Transplantstreatment1active_not_recruiting
NCT01679249
Blood Volume Analysis and Related Outcomes in HemodialysisNo drug interventionsNot AvailableNot Availablecompleted
NCT01619449
Continuous Renal Replacement Therapy in the Setting of Orthotopic Liver TransplantNo drug interventionstreatmentNot Availablewithdrawn
NCT04912024
Comparative Outcome Measures of Patients Receiving Acute Renal ThErapy StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT01877863
The Effect of Intradialytic Exercise on the Functional Capacity of Hemodialysis PatientsNo drug interventionstreatmentNot Availablecompleted
NCT06056739
Alio WEAR Study: Long-term Wear of the Alio PlatformNo drug interventionsotherNot Availablerecruiting
NCT02792530
Daily Sodium Intake in Anuric Hemodialysis Patients and Interdialytic Weight GainNo drug interventionstreatmentNot Availableunknown_status
NCT05738330
Symptom Monitoring in HemodialysisNo drug interventionssupportive_careNot Availablerecruiting
NCT01232257
Effect of N-acetylcysteine (NAC) on Hydrogen Sulfide (H2S) in Chronic Kidney Disease (CKD)treatment3completed
NCT04932876
The Response of the Immune System of Patients With End Stage Kidney Disease on Dialysis and Kidney Transplant Recipients Vaccinated for COVID-19No drug interventionsNot AvailableNot Availableunknown_status
NCT05741489
Continuous Glucose Monitoring in Patients With End-Stage Kidney Disease and Burnt-Out DiabetesNo drug interventionssupportive_careNot Availablecompleted
NCT00976846
Investigation of Performance and Compatibility of the Baxter Dialyzer Xenium XPH 210 During On-line HemodiafiltrationNo drug interventionstreatmentNot Availablecompleted
NCT04360408
The Energy Conservation Education InterventionNo drug interventionstreatmentNot Availableunknown_status
NCT03046732
Implementing "Explore Transplant"- A Pilot StudyNo drug interventionsotherNot Availablecompleted
NCT06660277
Dialysis with Expanded Solute RemovalNo drug interventionssupportive_careNot Availablenot_yet_recruiting
NCT06606275
The Safety and Effectiveness of Warfarin Vs Apixaban in Patients with NVAF/ VTE and ESKD on DialysisNot AvailableNot Availableactive_not_recruiting
NCT05832931
Parathyroid Hormone (PTH) Attenuation Trial in Hemodialysis-1No drug interventionstreatment3active_not_recruiting
NCT05769595
Single Dose Study of MK-2060 to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics in Older Japanese Participants on Dialysis (MK-2060-012)No drug interventionstreatment1completed
NCT04877041
Exercise and Cardiac Stunning During HDNo drug interventionstreatmentNot Availablerecruiting
NCT06622200
The Effect of Mindfulness on Emotional Regulations Skills and Quality of Life Among Patients on HemodialysisNo drug interventionssupportive_careNot Availablenot_yet_recruiting
NCT05957146
Kinetics of Extracellular Vesicles in HemodialysisNo drug interventionsNot AvailableNot Availablecompleted
NCT02823821
Randomised Evaluation of Sodium Dialysate Levels on Vascular EventsNo drug interventionshealth_services_research4recruiting
NCT05879302
Shared Decision Making for Kidney Transplant Candidates to Plan for an Organ Offer DecisionNo drug interventionshealth_services_researchNot Availablenot_yet_recruiting
NCT02222402
PrEscription of Intra-Dialytic Exercise to Improve quAlity of Life in Patients With Chronic Kidney DiseaseNo drug interventionstreatmentNot Availablecompleted
NCT01859884
Optimizing Kidney Transplant Informed ConsentNo drug interventionshealth_services_researchNot Availablecompleted
NCT05703633
Transplantation of Uncontrolled DCD Kidneys REconditioned by a Novel Ex-VIVo Perfusion MEthodNo drug interventionstreatment1 / 2not_yet_recruiting
NCT01921933
The Optiflow Patency and Maturation StudyNo drug interventionstreatmentNot Availablecompleted
NCT06377293
Effect of Dialysis-specific Therapeutic Diet on Biochemical Parameters in Dialysis PatientsNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT06477978
The Prevalence of Sarcopenia in a Cohort of Haemodialysis Patients and Its Correlation With MortalityNo drug interventionsdiagnosticNot Availablecompleted
NCT05614115
Safety, Tolerability, and Feasibility of Empagliflozin Therapy in Dialysis-dependent ESKDtreatment1recruiting
NCT01528800
Vitamin K to Attenuate Coronary Artery Calcification in Hemodialysis Patientsprevention2completed
NCT00062699
Evaluate the Survival Benefits of Zemplar Versus Calcijex in Subjects w/ Stage V Chronic Kidney Disease on Hemodialysistreatment4terminated
NCT00509236
Sitagliptin Versus Glipizide in Participants With Type 2 Diabetes Mellitus and End-Stage Renal Disease (MK-0431-073 AM1)treatment3completed
NCT05407896
End-Stage Kidney Disease Interactive Decision Aid for the Elderly (myKIDNEY)No drug interventionshealth_services_researchNot Availableunknown_status
NCT01111422
Anti-Oxidant Effect on Peritoneal Membrane in Peritoneal Dialysis (PD) Patientstreatment4unknown_status
NCT02628366
Major Outcomes With Personalized Dialysate TEMPeratureNo drug interventionspreventionNot Availablecompleted
NCT04484220
Ellipsys Vascular Access System Post Market Surveillance (PS) StudyNo drug interventionsotherNot Availableactive_not_recruiting
NCT04079582
Outcomes of a Higher vs. Lower Hemodialysate Magnesium Concentration (Dial-Mag Canada)No drug interventionspreventionNot Availableactive_not_recruiting
NCT05931276
CSP #2026 - Beta Blocker Dialyzability on Cardiovascular Outcomestreatment3recruiting
NCT01103076
Effects of High Cut-off (HCO) Hemodialysis on Central Memory CD4+ T and Treg Cells in Patients With End-stage Kidney DiseaseNo drug interventionstreatment2 / 3unknown_status
NCT05685394
DApagliflozin Cardiovascular Effects on Patients at End-stage REnal Diseasetreatment4recruiting
NCT02964429
Determination In-vivo KUF for Diacap Pro HemodialyserNo drug interventionsbasic_scienceNot Availablecompleted
NCT03142529
Traditional Chinese Medicine (TCM) Colon Dialysis Treats Non-dialysis End-Stage Kidney DiseaseNo drug interventionstreatment1 / 2unknown_status
NCT05656040
A Study of MK-2060 in Participants With Chronic and/or End-Stage Kidney Disease (MK-2060-011)No drug interventionstreatment1completed
NCT02590081
Effect of Sodium Rinsing Fluid on Blood Pressure and Interdialytic Weight Change in Hemodialysis PatientsNo drug interventionsNot Available4unknown_status
NCT01863914
Vascular Protective Effect of Rosuvastatin in Arteriovenous Fistulatreatment2completed
NCT06030050
Animal Assisted Intervention for Hemodialysis OutpatientsNo drug interventionstreatmentNot Availablewithdrawn
NCT05897502
Explore the Effectors of The Transtheoretical Model on Nutritional Education in Patients on HemodialysisNo drug interventionspreventionNot Availablecompleted
NCT06398002
The Effect of Increasing Dialysate Calcium on T50 in Subjects With Secondary Hyperparathyroidism and ESKDNo drug interventionstreatment2not_yet_recruiting
NCT02832505
Applications of MRI in Kidney DiseaseNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT02933697
Compare Apixaban and Vitamin-K Antagonists in Patients With Atrial Fibrillation (AF) and End-Stage Kidney Disease (ESKD)treatment3completed
NCT03149328
Electronic Patient-Reported Outcomes in Clinical Kidney Practice (ePRO Kidney)No drug interventionshealth_services_researchNot Availablecompleted
NCT04610593
Effects of a Mindfulness-based Intervention in Stress, Pain and Quality of Life in People Undergoing HemodialysisNo drug interventionstreatmentNot Availablecompleted
NCT02235571
iChoose Decision Kidney Aid for End-Stage Renal Disease PatientsNo drug interventionstreatmentNot Availablecompleted
NCT03191409
Interaction Research on Cognitive Impairment and Emotional Disorder in End-stage Renal DiseaseNo drug interventionsNot AvailableNot Availableunknown_status
NCT06086470
Evaluating the Use of the Qidni/D Hemodialysis System by Subjects With End-Stage Renal DiseaseNo drug interventionstreatmentNot Availablerecruiting
NCT02342119
Increasing Equity in Transplant Evaluation and Living Donor Kidney TransplantationNo drug interventionshealth_services_researchNot Availablecompleted
NCT00143741
Use of Atorvastatin (Lipitor) to Decrease Panel Reactive Antibody Titerstreatment1completed
NCT04634916
Post-market Surveillance Study of the BD® WavelinQ™ EndoAVF SystemNo drug interventionstreatmentNot Availablerecruiting
NCT02338635
Effect of Ursodeoxycholic Acid on Peritoneal Function in Patients on Peritoneal Dialysistreatment4unknown_status
NCT03683563
The Impact of Different Citrate Concentrations as Locking Solutions on Development of Biofilm and Function of Hemodialysis CathetersNo drug interventionspreventionNot Availableunknown_status
NCT04646226
The Arteriovenous Vascular (AV) ACCESS TrialNo drug interventionstreatmentNot Availablerecruiting
NCT05027074
Global Study of MK-2060 (Anti-Factor XI Monoclonal Antibody) in Participants With End Stage Renal Disease Receiving Hemodialysis (FXI Hemodialysis Study) (MK-2060-007)No drug interventionsprevention2active_not_recruiting
NCT06065982
Percutaneous Peritoneal Dialysis Catheter Insertion (PREDICT)No drug interventionsNot AvailableNot Availablerecruiting
NCT06089473
Virtual Home-based Physical Pre-habilitation in Kidney Transplant CandidatesNo drug interventionsotherNot Availablenot_yet_recruiting
NCT05515991
Symptom Management in Patients on DialysisNo drug interventionsscreeningNot Availableactive_not_recruiting
NCT03582592
Fluid Distribution Timetable on Adherence to Fluid Restriction of Patients With End-Stage Renal Disease on HemodialysisNo drug interventionssupportive_careNot Availablecompleted
NCT02694068
Biological Determinants of Peritoneal DialysisNo drug interventionsNot AvailableNot Availablecompleted
NCT02755610
Check List to Improve Patient Self-care and Product Defect Report in Continuous Ambulatory Peritoneal DialysisNo drug interventionshealth_services_researchNot Availableactive_not_recruiting
NCT04665310
Evaluation of Anti-rejection Drug, Tacrolimus, in African-Americans With Kidney Transplanttreatment4withdrawn
NCT02009514
Glucose Containing and Glucose Free Hemodialysate in Type 2 Diabetic PatientsNo drug interventionstreatment4completed
NCT05828823
Incremental Hemodialysis: The TwoPlus TrialNo drug interventionstreatmentNot Availablerecruiting