Type I Hypersensitivity

Also known as: Immediate hypersensitivity reactions / Immediate hypersensitivity reaction / Immediate Type Hypersensitivity / Hypersensitivity, Immediate / Immediate Hypersensitivity / Allergen-mediated IgE Allergy / Hypersensitivity type I / Hypersensitivity type I NOS / Immunoglobulin E-mediated allergic disorder (disorder)

Drug	Drug Name	Drug Description
DB00668	Epinephrine	A hormone and neurotransmitter used to treat allergic reactions, to restore cardiac rhythm, and to control mucosal congestion, glaucoma, and asthma.
DB00043	Omalizumab	A monoclonal anti-immunoglobulin E (IgE) antibody used to treat asthma, chronic idiopathic urticaria, chronic rhinosinusitis with nasal polyps, and IgE-mediated food allergy.

Drug	Drug Name	Target	Type
DB00668	Epinephrine	Alpha-1A adrenergic receptor	target
DB00668	Epinephrine	Beta-1 adrenergic receptor	target
DB00668	Epinephrine	Beta-2 adrenergic receptor	target
DB00668	Epinephrine	Solute carrier family 22 member 2	transporter
DB00668	Epinephrine	Solute carrier family 22 member 1	transporter
DB00668	Epinephrine	Cytochrome P450 2C9	enzyme
DB00668	Epinephrine	Cytochrome P450 3A4	enzyme
DB00668	Epinephrine	Alpha-1B adrenergic receptor	target
DB00668	Epinephrine	Alpha-1D adrenergic receptor	target
DB00668	Epinephrine	Alpha-2A adrenergic receptor	target
DB00668	Epinephrine	Alpha-2B adrenergic receptor	target
DB00668	Epinephrine	Tumor necrosis factor	target
DB00668	Epinephrine	Catechol O-methyltransferase	enzyme
DB00668	Epinephrine	Monoamine oxidase	enzyme
DB00043	Omalizumab	Immunoglobulin heavy constant epsilon	target

Drug	Drug Name	Phase	Status	Count
DB11980	Carbon black	1	Completed	1
DB19290	Monophosphoryl lipid A	1	Completed	2
DB12023	Benralizumab	2	Completed	1
DB19290	Monophosphoryl lipid A	2	Completed	3
DB15090	Tezepelumab	2	Completed	1
DB14973	Abrocitinib	3	Completed	2
DB12159	Dupilumab	3	Completed	2
DB00135	Tyrosine	3	Completed	1