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Displaying targets 276 - 300 of 6103 in total
TargetOrganismDescription# of Drugs
Acetylcholine receptor subunit alpha-type unc-38Caenorhabditis elegansAlpha subunit of nicotinic acetylcholine receptor (nAChR). Probably acts in cholinergic motoneurons to regulate presy...  more2Details
Acetylcholine receptor subunit alpha-type unc-63Caenorhabditis elegansAlpha subunit of nicotinic acetylcholine receptor (nAChR). Probably acts in cholinergic motoneurons to regulate presy...  more2Details
Acetylcholine receptor subunit beta-type lev-1Caenorhabditis elegansNon-alpha subunit of nicotinic acetylcholine receptor (nAChR). Involved in nAChR sensitivity to nicotine.1Details
Acetylcholine receptor subunit beta-type unc-29Caenorhabditis elegansNon-alpha subunit of nicotinic acetylcholine receptor (nAChR). Involved in nAChR sensitivity to nicotine and levasimole.2Details
AcetylcholinesteraseHumansHydrolyzes rapidly the acetylcholine neurotransmitter released into the synaptic cleft allowing to terminate the sign...  more162Details
Acetylglutamate kinaseEscherichia coli (strain K12)Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.3Details
Acetylglutamate kinasePseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.1Details
Acetylserotonin O-methyltransferaseHumansCatalyzes the transfer of a methyl group onto N-acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine)2Details
Acid ceramidaseHumansLysosomal ceramidase that hydrolyzes sphingolipid ceramides into sphingosine and free fatty acids at acidic pH. Ceram...  more1Details
Acid-sensing ion channel 1HumansForms voltage-independent, pH-gated trimeric sodium channels that act as postsynaptic excitatory receptors in the ner...  more2Details
Acid-sensing ion channel 2HumansForms pH-gated trimeric sodium channels that act as postsynaptic excitatory sensors in the nervous system. Upon extra...  more1Details
Acid-sensing ion channel 3HumansForms pH-gated heterotrimeric sodium channels that act as postsynaptic excitatory receptors in the nervous system. Up...  more2Details
Acidic amino acid decarboxylase GADL1HumansMay catalyze the decarboxylation of L-aspartate, 3-sulfino-L-alanine (cysteine sulfinic acid), and L-cysteate to beta...  more1Details
Acidic cytochrome c3Desulfovibrio africanusExchanges electrons specifically with the basic cytochrome c3.1Details
Acidic mammalian chitinaseHumansDegrades chitin and chitotriose. May participate in the defense against nematodes, fungi and other pathogens. Plays a...  more1Details
Aclacinomycin 10-hydroxylase RdmBStreptomyces purpurascensInvolved in the biosynthesis of the anthracycline aclacinomycin which is an aromatic polyketide antibiotic that exhib...  more3Details
Aclacinomycin methylesterase RdmCStreptomyces purpurascensInvolved in the biosynthesis of the anthracycline aclacinomycin which is an aromatic polyketide antibiotic that exhib...  more2Details
Aconitate hydratase BEscherichia coli (strain K12)Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation rout...  more1Details
Aconitate hydratase, mitochondrialHumansCatalyzes the isomerization of citrate to isocitrate via cis-aconitate6Details
AcrosinHumansAcrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity,...  more1Details
ActII proteinStreptomyces coelicolorTetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structur...  more1Details
Actin nucleation-promoting factor WASHumansEffector protein for Rho-type GTPases that regulates actin filament reorganization via its interaction with the Arp2/...  more1Details
Actin, alpha skeletal muscleHumansActins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously express...  more13Details
Actin, aortic smooth muscleHumansActins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously express...  more1Details
Actin, cytoplasmic 1HumansActin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cyto...  more4Details
Displaying targets 276 - 300 of 6103 in total